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1. 发明授权

US11852625B1 Systems and methods for analyzing exhaled breath 有权
公开(公告)号：US11852625B1
公开(公告)日：2023-12-26
申请号：US16849733
申请日：2020-04-15
申请人： Verily Life Sciences LLC
发明人： Benjamin Krasnow , Eric Peeters
IPC分类号： G01N33/497 , A61B5/097 , A61B5/08 , G01N31/22
CPC分类号： G01N33/497 , A61B5/082 , A61B5/097 , G01N31/223
摘要： Described herein are systems and methods of collecting, processing, and analyzing breath exhaled from a subject. Specifically, described herein are systems and methods for minimizing the amount of breath needed for analysis. Further disclosed herein are systems and methods to analyze compounds contained in a subject's breath that are indicative of certain ailments and/or present in a low concentration in the subject's breath. The systems can include a reaction chamber, a breath inlet, a reactant inlet, a fluid atomizer, and a receiving substrate for analyzing the process subject's breath. The methods can include reacting a subject's breath with a reactant to analyze the contents of the subject's breath.

2. 发明授权

US10845265B2 Gas indicator 有权
公开(公告)号：US10845265B2
公开(公告)日：2020-11-24
申请号：US16188628
申请日：2018-11-13
申请人： Thanner A/S
发明人： Peter Jensen
IPC分类号： G08B23/00 , G01M3/22 , G01N33/00 , B63C9/04 , G01N31/22 , G01N21/78
CPC分类号： G01M3/227 , B63C9/04 , G01N31/223 , G01N33/004 , B63C2009/042 , G01N21/783
摘要： The object of the invention is to provide means and method of monitoring target gas content in gas tight membrane enclosing a volume containing an object. The visible gas indicator comprises means for being fastened to a gas tight membrane enclosing a volume containing an object, where the gas indicator comprises a chamber having a transparent window. The chamber is in gas communication with the interior of the volume. The window is arranged outside said volume, and a substrate is arranged inside said chamber and visible from outside said volume, where said substrate changes colours when exposed to a target gas.

3. 发明申请

US20180164263A1 OPTOCHEMICAL SENSOR 审中-公开
公开(公告)号：US20180164263A1
公开(公告)日：2018-06-14
申请号：US15834359
申请日：2017-12-07
申请人： Mettler-Toledo GmbH
发明人： Milan Fischer , Lilya Ulmer , Francesca Venturini
IPC分类号： G01N31/22 , G01N21/64 , G01K11/12
CPC分类号： G01N31/223 , G01K11/12 , G01K11/20 , G01N21/6428 , G01N21/643 , G01N21/77 , G01N21/8507 , G01N31/221 , G01N31/225 , G01N2021/6432 , G01N2021/6434 , G01N2021/6441 , G01N2021/7786
摘要： A sensor (202) uses an optical-sensing technique for determining more than one parameter in a measurement medium (204). The sensor has an optochemical sensitive element (208) with a first sensing layer (228) and a second sensing layer (230). Each of the sensing layers is arranged on a substrate (222). The first sensing layer has a first indicator (236) that determines a first parameter and the second sensing layer has a second indicator (238) that determines a second parameter in the measurement medium.

4. 发明申请

US20170330777A1 PLASMA-PROCESSING DETECTION INDICATOR IN WHICH METAL OXIDE FINE PARTICLES ARE USED AS COLOR-CHANGE LAYER 审中-公开
公开(公告)号：US20170330777A1
公开(公告)日：2017-11-16
申请号：US15529404
申请日：2015-11-24
申请人： SAKURA COLOR PRODUCTS CORPORATION
发明人： Keita Hishikawa , Kazuhiro Uneyama
IPC分类号： H01L21/67 , H01J37/244 , G01N21/78
CPC分类号： H01L21/67253 , C01G29/00 , C01G31/02 , C01G39/02 , C01G41/02 , C09D11/037 , C09D11/50 , C23C14/52 , C23C16/50 , C23C16/52 , C23C24/085 , C23C28/04 , C23C28/042 , C23C28/322 , C23C28/345 , C23C28/3455 , C23C28/40 , G01N21/75 , G01N21/78 , G01N21/783 , G01N31/223 , G01N31/226 , G01N2021/751 , H01J37/244 , H01J37/32917 , H01J37/32935 , H01L21/3065 , H01L21/31 , H01L21/32136 , H05H1/00
摘要： The present invention provides a plasma treatment detection indicator including a color-changing layer that changes color by plasma treatment, exhibiting excellent heat resistance, with the gasification of the color-changing layer or the scattering of the fine debris of the color-changing layer caused by the plasma treatment being suppressed to the extent that electronic device properties are not affected. Specifically, the present invention provides a plasma treatment detection indicator comprising a color-changing layer that changes color by plasma treatment, the color-changing layer comprising metal oxide fine particles containing at least one element selected from the group consisting of Mo, W, Sn, V, Ce, Te, and Bi, the metal oxide fine particles having a mean particle size of 50 μm or less.

5. 发明申请

US20170212048A1 ANALYTE SENSING SYSTEM AND METHOD UTILIZING SEPARATE EQUILIBRIUM AND MEASUREMENT CHAMBERS 审中-公开
公开(公告)号：US20170212048A1
公开(公告)日：2017-07-27
申请号：US13823897
申请日：2011-09-30
申请人： Govind RAO , Yordan KOSTOV , Xudong GE , Leah TOLOSA , Hung LAM , Robert HENDERSON
发明人： Govind RAO , Yordan KOSTOV , Xudong GE , Leah TOLOSA , Hung LAM , Robert HENDERSON
IPC分类号： G01N21/64 , G01N33/18 , G01N31/22 , G01N21/78
CPC分类号： G01N21/643 , G01N21/77 , G01N21/78 , G01N31/223 , G01N33/1886 , G01N2021/7733 , G01N2021/7786 , G01N2201/0612 , G01N2201/062
摘要： An analyte sensing system is provided that utilizes separate and decoupled equilibrium and measurement chambers for improved sensitivity and stability. The system and method are particularly suited for monitoring of CO2 levels in oceans or other bodies of water.

6. 发明授权

US09677980B2 Method of entrapping chlorine dioxide gas, method of determining concentration of chlorine dioxide and entrapping agent for chlorine dioxide 有权
公开(公告)号：US09677980B2
公开(公告)日：2017-06-13
申请号：US14765739
申请日：2014-01-21
申请人： TAIKO PHARMACEUTICAL CO., LTD.
发明人： Shigeo Asada , Koichi Nakahara , Kazuhiko Taguchi
IPC分类号： G01N1/40 , G01N31/22 , B01D53/14 , C01B11/02 , G01N1/22
CPC分类号： G01N1/4044 , B01D53/1493 , B01D2252/50 , C01B11/022 , G01N1/2202 , G01N1/2273 , G01N31/223 , Y10T436/19
摘要： A method of entrapping chlorine dioxide gas, including the steps of using an aqueous solution containing an alkaline substance and an iodide and bringing air containing the chlorine dioxide gas into contact with the aqueous solution.

7. 发明申请

US20170074847A1 Fresh Check Monitoring System 审中-公开
标题翻译：新鲜检查监控系统
公开(公告)号：US20170074847A1
公开(公告)日：2017-03-16
申请号：US14854337
申请日：2015-09-15
申请人： Krysten Nyckole Smith , Clarence Neal Stidham
发明人： Krysten Nyckole Smith , Clarence Neal Stidham
IPC分类号： G01N33/02 , C12Q1/04
CPC分类号： G01N33/02 , C12Q1/22 , G01N31/223
摘要： A device for monitoring the freshness of food items is provided; made up of plastic and thermos-measuring product. It detects mold or bad gases from the stored food when it reacts with the gasses released by microorganisms during food spoilage or mold. It provides visual indication to the user about the freshness of food items by changing colors. When it stays green the food is safe to eat and when food becomes unsafe it shows red indication to the user. It can be placed in a redesigned Tupperware lid, cup, plates, zip lock bag, or directly built into all prepackaged organic food products; such as prepackaged meat, milk jugs, juices, animal feed, plant seed or anything with an expiration date. It is designed for one time use only.
摘要翻译：提供了一种用于监测食品新鲜度的装置; 由塑料和热量测量产品组成。当食物腐败或模具中与微生物释放的气体发生反应时，可以从存储的食物中检测霉菌或坏气体。它通过改变颜色向用户提供关于食物的新鲜度的视觉指示。当它保持绿色时，食物是安全的食物，当食物变得不安全时，向用户显示红色指示。它可以放置在重新设计的Tupperware盖子，杯子，板子，拉链锁袋中，或直接内置到所有预先包装的有机食品中; 例如预包装的肉，牛奶壶，果汁，动物饲料，植物种子或任何有效期的物品。它是专为一次性使用而设计的。

8. 发明授权

US09518964B2 Method for identifying electrophiles and nucleophiles in a sample 有权
标题翻译：识别样品中亲电子和亲核试剂的方法
公开(公告)号：US09518964B2
公开(公告)日：2016-12-13
申请号：US13086486
申请日：2011-04-14
申请人： Yoav Eichen , Shay Tal , Yael Abraham , Husein Salman , Elana Borzin , Carmit Hertzog-Ronen
发明人： Yoav Eichen , Shay Tal , Yael Abraham , Husein Salman , Elana Borzin , Carmit Hertzog-Ronen
IPC分类号： C40B30/00 , C40B40/00 , G01N31/22 , G01N33/00 , G01N21/77 , G01N21/64
CPC分类号： G01N31/22 , G01N31/223 , G01N31/224 , G01N33/0036 , G01N33/0057 , G01N2021/6439 , G01N2021/773 , Y10T436/23
摘要： A method and device for identifying a molecule in a sample, the molecule comprising an electrophilic or nucleophilic moiety. The method comprises contacting the sample with a plurality of chemosensors, each of the chemosensors comprising a π-conjugated system and a moiety having a nucleophilic property or an electrophilic property; and measuring an electromagnetic property of each of the chemosensors in the sample; whereby the pattern of changes in the electromagnetic properties of the plurality of chemosensors after chemically reacting with the electrophile or nucleophile of the molecule identifies the molecule in said sample. The device comprises a substrate carrying a plurality of chemosensor molecules having at least one predetermined electromagnetic property, the at least one electromagnetic property being changeable by subjecting the chemosensor molecules to a sample containing at least one electrophile or nucleophile, wherein the pattern of change of the electromagnetic property of the plurality of chemosensor molecules allows the device to identify the electrophile or nucleophile in the sample.
摘要翻译：用于鉴定样品中分子的方法和装置，所述分子包含亲电子部分或亲核部分。该方法包括使样品与多种化学传感器接触，每种化学传感器包含π共轭体系和具有亲核性质或亲电性质的部分; 并测量样品中每种化学传感器的电磁特性; 由此在与分子的亲电子试剂或亲核试剂发生化学反应之后，多种化学传感器的电磁特性的变化模式识别所述样品中的分子。该装置包括承载多个具有至少一个预定电磁特性的化学传感器分子的基底，所述至少一个电磁特性可通过使化学传感器分子经受含有至少一种亲电子试剂或亲核试剂的样品而变化，其中，多个化学传感器分子的电磁特性允许该装置鉴定样品中的亲电试剂或亲核试剂。

9. 发明授权

US09410941B2 Composition for the detection of alcohol vapors in an air sample 有权
标题翻译：用于检测空气样品中酒精蒸汽的组成
公开(公告)号：US09410941B2
公开(公告)日：2016-08-09
申请号：US14782680
申请日：2013-04-08
申请人： Pietro Caimmi
发明人： Pietro Caimmi , Marco Marchetti , Norberto Roveri , Rocco Mercuri , Eros D'Amen
IPC分类号： G01N33/497 , G01N33/00 , G01N31/22 , G01N33/98 , A61B5/087 , G01N21/78 , G01N33/52 , G01N21/77 , A61B5/08 , A61B5/097 , G01N27/404 , A61K31/205 , A61B5/0452 , A61B5/00
CPC分类号： G01N33/4972 , A61B5/0452 , A61B5/082 , A61B5/097 , A61B5/4845 , A61K31/205 , G01N21/77 , G01N21/783 , G01N27/4045 , G01N31/22 , G01N31/223 , G01N33/0047 , G01N33/52 , G01N33/98 , G01N2800/307
摘要： The present invention relates to a silica gel-based composition capable of changing color when placed in contact with alcohol vapors. Said composition is particularly useful for preparing devices for the detection of alcohol, for example devices for carrying out an alcohol test on samples of air exhaled by individuals when subjected to checks by the police or competent authorities.
摘要翻译：本发明涉及当与醇蒸气接触时能够改变颜色的基于硅胶的组合物。所述组合物特别可用于制备用于检测酒精的装置，例如用于对受到警察或主管当局检查的个人呼出的空气样品进行酒精测试的装置。

10. 发明申请

US20160139049A1 OPTICAL SENSOR AND MEASURING APPARATUS FOR QUANTITATIVELY DETECTING AN ANALYTE IN A SAMPLE 审中-公开
标题翻译：用于定量检测样品中的分析仪的光学传感器和测量装置
公开(公告)号：US20160139049A1
公开(公告)日：2016-05-19
申请号：US15005664
申请日：2016-01-25
申请人： PreSens Precision Sensing GmbH
发明人： Daniel Riechers , Athanasios Apostolidis
IPC分类号： G01N21/64 , G01N33/00
CPC分类号： G01N21/643 , G01N21/78 , G01N31/223 , G01N33/0062 , G01N33/0073 , G01N2021/6439
摘要： A sensor for quantitatively detecting an analyte in a sample, wherein an optical behavior of at least one dye depending on the analyte is used for the quantitative detection is provided. The at least one dye is contained in a medium. A restrictor is provided in order to mechanically limit volume changes of the medium. Furthermore, an osmolality in the medium is set in such a way that the osmolality is higher than the highest sample osmolality for which the sensor is to be used. The cooperation of the restrictor with the specified high osmolality results in a greatly reduced osmolality cross-sensitivity of the sensor. The restrictor can be embedded into the medium as a membrane, mat, braided material, woven fabric, or mesh. Alternatively, the restrictor can also include a carrier plate having a plurality of recesses, in which the medium is arranged. A corresponding measuring apparatus is also provided.
摘要翻译：提供了用于定量检测样品中的分析物的传感器，其中使用至少一种依赖于分析物的染料的光学行为进行定量检测。将至少一种染料包含在培养基中。提供限制器以便机械地限制介质的体积变化。此外，培养基中的重量摩尔渗透压浓度设定为使得重量摩尔渗透压浓度高于要使用传感器的最高样品渗透压浓度。限制器与指定的高重量摩尔渗透压浓度的合作导致传感器的重复摩尔渗透压浓度交叉敏感性大大降低。限流器可以作为膜，垫，编织材料，机织织物或网状物嵌入介质中。或者，限流器还可以包括具有多个凹部的载体板，其中布置介质。还提供了相应的测量装置。

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