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    • 4. 发明申请
    • Dynamic generation of wrapper classes to implement call-by-value semantics
    • 动态生成包装类来实现逐个值语义
    • US20060107222A1
    • 2006-05-18
    • US10938963
    • 2004-09-10
    • William Gallagher
    • William Gallagher
    • G06F3/00G06F9/44
    • G06F9/548G06F9/541
    • A system and method for dynamically generating proxy classes in order to enforce call-by-value semantics between clients and EJBs collocated with a virtual machine. The virtual machine can be a Java virtual machine (JVM) or some other type of virtual machine. The proxy classes are dynamically generated at runtime using dynamic byte code generation. Generated proxies are then interposed between a client and an EJB. The interposition of the generated proxies allows the proxies to intercept communication between the client and the EJB. The dynamically generated wrapper classes may be used in any system wherein a first entity invokes a second entity, wherein the second entity has an interface that can be retrieved or introspected and utilizes call-by-value semantics.
    • 一种用于动态生成代理类的系统和方法,以便在与虚拟机并置的客户机和EJB之间强制使用逐个值的语义。 虚拟机可以是Java虚拟机(JVM)或其他类型的虚拟机。 代理类在运行时使用动态字节码生成动态生成。 然后将生成的代理插入到客户端和EJB之间。 生成的代理的插入允许代理拦截客户端和EJB之间的通信。 动态生成的包装器类可以在其中第一实体调用第二实体的任何系统中使用,其中第二实体具有可被检索或内省的接口,并且利用逐个值语义。
    • 5. 发明申请
    • Compounds useful as photodynamic therapeutic agents
    • 可用作光动力治疗剂的化合物
    • US20050107335A1
    • 2005-05-19
    • US10508754
    • 2003-03-24
    • Donal O'SheaJohn KilloranWilliam Gallagher
    • Donal O'SheaJohn KilloranWilliam Gallagher
    • C07F5/02A61K31/69
    • C07F5/022
    • The present invention relates to compounds of the formula or a salt, metal complex or hydrate or other solvate thereof, wherein: M is a chelating agent; R1, R2, R3, R4, R5 and R6 are independently selected from the group consisting of: H; a substituted or unsubstituted, saturated or unsaturated, cyclic, moiety; a substituted or unsubstituted, saturated or unsaturated, heterocyclic moiety; or a substituted or unsubstituted, saturated or unsaturated, straight or branched chain alkyl or acyl moiety; and R2 and R5 may also be independently a heavy atom or a water-solubilizing group. The present invention also relates to use of these compounds in the therapy in vivo or in vitro of a photosensitive target biological cell by irradiation, as well as methods of treating a photosensitive target biological cell in vivo or in vitro. Finally, the present invention relates to pharmaceutical compositions, comprising these compounds, in association with a pharmaceutically acceptable diluent or carrier.
    • 本发明涉及下式的化合物或其盐,金属配合物或水合物或其它溶剂化物,其中:M为螯合剂; R 1,R 2,R 3,R 4,R 5和R 5, R 6独立地选自:H; 取代或未取代的饱和或不饱和的环状部分; 取代或未取代的饱和或不饱和的杂环部分; 或取代或未取代的饱和或不饱和的直链或支链烷基或酰基部分; R 2和R 5也可以独立地是重原子或水溶性基团。 本发明还涉及这些化合物在体内或体外通过照射进行光敏靶生物细胞治疗的用途,以及在体内或体外治疗感光性靶生物细胞的方法。 最后,本发明涉及与药学上可接受的稀释剂或载体结合的包含这些化合物的药物组合物。
    • 9. 发明授权
    • Tuna chunking apparatus
    • 金枪鱼块装置
    • US5562533A
    • 1996-10-08
    • US546823
    • 1995-10-23
    • William Gallagher
    • William Gallagher
    • B26D1/553A22C25/18
    • B26D1/553
    • A tuna chunking apparatus including a base portion that has a base front end and a base back end with a handle. The base front end has a pair of hinged extensions. The base portion has a base top and a base bottom with an opening. The base bottom is positioned on a chum bucket. The opening of the base portion has a front wall, a back wall, with a pair of side walls that have six rigid blades with a space between each blade. Included is a plate that has a plate front end and a plate back end with a handle. The plate front end has three hinged extensions that are capable of interlocking with a pair of hinged extensions of the base portion. The plate has a plate top with five rectangular projections and a front projection, with each projection proportionally spaced from another projection. Lastly, the handle of the plate is capable of rotating the plate toward the base portion along the hinges to force a fish positioned on the base top to be chunked by the blades.
    • 一种金枪鱼块块装置,其包括具有基部前端的基部和具有手柄的基部后端。 基座前端有一对铰链延长部分。 基部具有基部顶部和具有开口的底部底部。 底部底部位于槽桶上。 基部的开口具有前壁,后壁,具有一对侧壁,其具有六个刚性叶片,每个叶片之间具有空间。 包括板,其具有板前端和具有手柄的板后端。 板前端具有三个铰链延伸部,其能够与基部的一对铰链延伸部互锁。 板具有板顶,其具有五个矩形突起和前突起,每个突起与另一突起成比例地间隔开。 最后,板的手柄能够沿着铰链将板旋转到基部,以迫使位于基座顶部的鱼被叶片分块。
    • 10. 发明授权
    • Trailer for carrying large vehicles
    • 拖车运载大型车辆
    • US4494766A
    • 1985-01-22
    • US456272
    • 1983-01-06
    • Edward L. McHughJames C. McHughGerard J. McHughWilliam GallagherDavid Schmidt
    • Edward L. McHughJames C. McHughGerard J. McHughWilliam GallagherDavid Schmidt
    • B60G17/052B60P3/07B62D13/04B62D61/10B62D63/06
    • B62D63/068B60G17/0523B60P3/07B62D13/04B62D61/10
    • A drawbar trailer for transporting very long, very heavy, substantially rigid loads, the trailer having a load support platform carried by at least one front and at least one rear axle and separable wheel assembly, the trailer comprising: an adjustable suspension system having inflatable members disposed between the platform and the front and rear axles for selectively raising and lowering the front and rear of the platform and for selectively raising and lowering the sides of the platform; the drawbar being pivotably mounted to the platform about a substantially vertical axis; a mechanism, preferably hydraulic, for turning the wheels of at least one of the front and rear axle and wheel assemblies; an automatic control system for activating the turning mechanism in response to pivotal movements of the drawbar; and, members for securing the load to the platform, whereby the tilt axes of the load support platform can be adjusted with respect to the axle and wheel assemblies, and in turn, with respect to terrain features. In the presently preferred embodiment, the drawbar trailer is particularly adapted for transporting rapid transit subway cars, railcars and like vehicles having internal suspension systems. Such a specially adapted drawbar trailer further comprises support members for holding and immobilizing the bodies of the carried vehicles with respect to the platform, preventing movement of the vehicle bodies on their internal suspension systems. The load support platform may be inclined about its tilt axes to facilitate loading, carrying and unloading the carried vehicle.
    • 一种牵引车拖车,用于运输非常长而非常重的,基本上刚性的载荷,所述拖车具有由至少一个前部和至少一个后桥和可分离轮组件承载的负载支撑平台,所述拖车包括:可调节的悬挂系统,其具有可充气构件 设置在平台与前轴和后轴之间,用于选择性地升高和降低平台的前后,并且用于选择性地升高和降低平台的侧面; 所述牵引杆围绕基本垂直的轴线可枢转地安装到所述平台; 用于转动前轴和后轴与车轮组件中的至少一个的车轮的优选液压的机构; 用于响应于牵引杆的枢转运动来启动转动机构的自动控制系统; 以及用于将负载固定到平台的构件,由此可以相对于车轴和车轮组件而调节负载支撑平台的倾斜轴线,并且还可以相对于地形特征来调节负载支撑平台的倾斜轴。 在目前优选的实施例中,牵引车拖车特别适于运输具有内部悬挂系统的快速过境地铁车厢,轨道车辆等。 这种特别适应的牵引车拖车还包括用于相对于平台保持和固定携带车辆的车身的支撑构件,防止车体在其内部悬架系统上的运动。 负载支撑平台可以围绕其倾斜轴线倾斜,以便于装载,携带和卸载所携带的车辆。