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1. 发明授权

US5409956A Indan derivative and thromboxane antagonist containing the same 失效
标题翻译： Indan衍生物和含有相同的血栓素拮抗剂
公开(公告)号：US5409956A
公开(公告)日：1995-04-25
申请号：US107823
申请日：1993-08-30
申请人： Kiyoshi Yoshida , Yoshiaki Yamaji , Tadashi Kurimoto , Ryuichi Sato , Motoki Torizuka
发明人： Kiyoshi Yoshida , Yoshiaki Yamaji , Tadashi Kurimoto , Ryuichi Sato , Motoki Torizuka
IPC分类号： A61K31/19 , A61K31/195 , A61K31/22 , A61K31/38 , A61K31/50 , A61K38/22 , A61K38/55 , A61P9/00 , A61P43/00 , C07C311/13 , C07C311/17 , C07C311/19 , C07C311/29 , C07C311/42 , C07D231/20 , C07D237/04 , C07D333/34 , A01N37/12 , C07C311/00
CPC分类号： A61K38/2242 , A61K38/55 , A61K38/556 , C07C311/13 , C07C311/17 , C07C311/19 , C07C311/29 , C07C311/42 , C07D231/20 , C07D237/04 , C07D333/34 , C07C2102/08
摘要： The present invention relates to indan derivatives represented by the formula (1) or pharmaceutically acceptable salts thereof: ##STR1## [wherein R.sup.1 represents C1 to C12 alkyl, benzyl, styryl, naphthyl, optionally substituted phenyl or optionally substituted thienyl; R.sup.2 represents carboxyl, C1 to C4 alkoxycarbonyl, ##STR2## Y represents --(CH.sub.2).sub.p -- (wherein p represents an integer of 0 to 5), --CO--(CH.sub.2).sub.q .about., --CH(OH)--(CH.sub.2).sub.q .about., (wherein q represents an integer of 1 to 4, and the symbol .about. represents a linkage to R.sup.2), oxymethylene or ethylene; and n represents an integer of 1 to 4]. The compounds according to the present invention potently antagonize the action of thromboxane A.sub.2, and therefore useful for the treatment and prevention of diseases caused by thromboxane A.sub.2 such as angiosis, vasospasm, asthma and the like.
摘要翻译： PCT No.PCT / JP92 / 00236 Sec。 371日期：1993年8月30日 102（e）日期1993年8月30日PCT提交1992年2月28日PCT公布。出版物WO92 / 15558 本发明涉及由式（1）表示的茚满衍生物或其药学上可接受的盐：其中R1表示C1〜C12烷基，苄基，苯乙烯基，萘基，任意取代苯基或任选取代的噻吩基; R 2表示羧基，C 1〜C 4烷氧基羰基，Y表示 - （CH 2）p - （其中p表示0〜5的整数），-CO-（CH 2）q DIFFERENCE，-CH（OH） - （CH 2）q DIFFERENCE，（其中q表示1至4的整数，符号DIFFERENCE表示与R 2的连接），甲醛或亚乙基; n表示1〜4的整数]。根据本发明的化合物有效地拮抗血栓素A2的作用，因此可用于治疗和预防由血栓素A2引起的疾病，例如血管紧张素，血管痉挛，哮喘等。

2. 发明授权

US08514407B2 Surface shape measurement apparatus 失效
标题翻译：表面形状测量装置
公开(公告)号：US08514407B2
公开(公告)日：2013-08-20
申请号：US12891648
申请日：2010-09-27
申请人： Ryuichi Sato
发明人： Ryuichi Sato
IPC分类号： G01B11/02
CPC分类号： G01B11/24
摘要： An apparatus for measuring a shape of a surface, comprises a measurement head which measures a distance between a reference point and the surface by detecting interference between test light obtained when light that passes through the reference point is emitted, is reflected by the surface, and returns to the reference point, and reference light, a scanning mechanism which scans the measurement head, and a processor which calculates the shape of the surface based on the distance measured using the measurement head and coordinates of the reference point.
摘要翻译：一种用于测量表面形状的装置，包括：测量头，其通过检测通过所述参考点的光发射时获得的测试光之间的干涉来测量参考点与所述表面之间的距离，所述测量头被所述表面反射;以及返回到参考点，参考光，扫描测量头的扫描机构，以及基于使用测量头测量的距离和参考点的坐标来计算表面的形状的处理器。

3. 发明授权

US08411280B2 Surface shape measurement apparatus 有权
标题翻译：表面形状测量装置
公开(公告)号：US08411280B2
公开(公告)日：2013-04-02
申请号：US12891736
申请日：2010-09-27
申请人： Ryuichi Sato
发明人： Ryuichi Sato
IPC分类号： G01B11/02 , G01B11/30
CPC分类号： G01B11/24 , G01B21/042
摘要： An apparatus for measuring a shape of a surface, comprises a measurement head which measures at least one of a distance between a reference point and the surface and a direction of a normal from the surface to the reference point, a scanning mechanism which scans the measurement head, and a processor which calculates the shape of the surface based on a measurement result measured using the measurement head and coordinates of the reference point, wherein the coordinates of the reference point are calibrated using a measurement result measured by scanning the measurement head along a scanning path in association with a first surface to be measured, and a shape of a second surface to be measured is calculated based on a measurement result measured by scanning the measurement head along the same scanning path in association with the second surface, and the calibrated coordinates of the reference point.
摘要翻译：一种用于测量表面形状的装置，包括：测量头，其测量参考点和表面之间的距离和从表面到参考点的法线方向中的至少一个;扫描机构，其扫描测量头部和处理器，其基于使用测量头和参考点的坐标测量的测量结果来计算表面的形状，其中使用通过沿着测量头扫描测量头测量的测量结果来校准参考点的坐标基于通过沿着与第二表面相关联的相同扫描路径扫描测量头而测量的测量结果来计算待测量的第二表面的形状，并且校准的第二表面与待测量的第一表面相关联的扫描路径参考点的坐标。

4. 发明申请

US20070029724A1 Sheet processing apparatus and sheet bundle alignment method 有权
公开(公告)号：US20070029724A1
公开(公告)日：2007-02-08
申请号：US11545474
申请日：2006-10-11
申请人： Ryuichi Sato
发明人： Ryuichi Sato
IPC分类号： B65H31/26
CPC分类号： B65H29/001 , B65H31/26 , B65H31/36 , B65H2404/1114 , B65H2404/1521 , B65H2701/176 , B65H2801/27
摘要： When a new paper sheet is supplied onto a compiling tray, a sub-paddle holds down paper sheets having already been stacked on the compiling tray until a leading edge of the new paper sheet S touches the stacked paper sheets. Thereafter, the sub-paddle gets apart from the sheets stacked on the compiling tray with timing, with which the rear edge of the new paper sheet falls on the compiling tray.

5. 发明授权

US5774205A Exposure and method which tests optical characteristics of optical elements in a projection lens system prior to exposure 失效
标题翻译：在曝光之前测试投影透镜系统中的光学元件的光学特性的曝光装置和方法
公开(公告)号：US5774205A
公开(公告)日：1998-06-30
申请号：US682959
申请日：1996-07-18
申请人： Ryuichi Sato
发明人： Ryuichi Sato
IPC分类号： G03F7/20 , G03F9/00 , H01L21/027 , G03B27/54 , G01B11/00 , G03B27/42 , G03B27/52
CPC分类号： G03F7/70575 , G03F7/706 , G03F9/70
摘要： An exposure apparatus for and a method of producing devices, in which an original pattern such as a reticle is projected onto an object such as a wafer to be exposed, through a projection optical system. The projection optical system includes at least one optical element, optical characteristics thereof having been tested using a measuring beam having a first wavelength region. An exposure light source emits a light beam having a second wavelength region, selected independently from the first wavelength region, to irradiate the original pattern with the beam from the exposure light source, so that an image of the pattern is projected onto the object through the projection optical system, thereby exposing the object to produce the device.
摘要翻译：一种用于制造装置的曝光装置及其制造方法，其中通过投影光学系统将诸如掩模版之类的原始图案投影到待暴露的晶片等物体上。投影光学系统包括至少一个光学元件，其光学特性已经使用具有第一波长区域的测量光束进行了测试。曝光光源发射具有独立于第一波长区域选择的第二波长区域的光束，以从来自曝光光源的光束照射原始图案，使得图案的图像通过投影光学系统，从而暴露物体以产生该装置。

6. 发明授权

US4328216A Novel organosilicon compounds and anti-tumor agents containing the same 失效
标题翻译：新型有机硅化合物和含有相同的抗肿瘤剂
公开(公告)号：US4328216A
公开(公告)日：1982-05-04
申请号：US102225
申请日：1979-12-10
申请人： Shigeshi Toyoshima , Ryuichi Sato , Koichi Ito , Toshio Shinohara , Yasushi Yamamoto , Shoji Ichinohe
发明人： Shigeshi Toyoshima , Ryuichi Sato , Koichi Ito , Toshio Shinohara , Yasushi Yamamoto , Shoji Ichinohe
IPC分类号： A61K31/695 , A61P35/00 , C07F7/08 , C07F7/10
CPC分类号： C07F7/0818
摘要： The invention provides a novel anti-tumor agent highly effective for inhibiting growth of several tumor or cancer cells with low toxicity. The active ingredient contained in the anti-tumor agent is an .omega.-triorganosilyl-substituted linear alkanoic acid anilide which is a hitherto unknown novel compound prepared by the reaction of corresponding acid chloride and aniline.
摘要翻译：本发明提供了用于抑制几种具有低毒性的肿瘤或癌细胞生长的新型抗肿瘤剂。包含在抗肿瘤剂中的活性成分是ω-三有机甲硅烷基取代的直链烷酸酰苯胺，它是迄今未知的通过相应的酰氯和苯胺反应制备的新化合物。

7. 发明授权

US4278666A Novel organosilicon compounds and anti-transplanted tumor agents containing the same 失效
标题翻译：新型有机硅化合物和含有其的抗移植肿瘤剂
公开(公告)号：US4278666A
公开(公告)日：1981-07-14
申请号：US124957
申请日：1980-02-26
申请人： Shigeshi Toyoshima , Ryuichi Sato , Koichi Ito , Toshio Shinohara , Yasushi Yamamoto
发明人： Shigeshi Toyoshima , Ryuichi Sato , Koichi Ito , Toshio Shinohara , Yasushi Yamamoto
IPC分类号： A61K31/695 , A61P35/00 , C07F7/08 , C07F7/10 , A61K31/725 , A01N55/00
CPC分类号： C07F7/0818
摘要： The invention provides a novel class of organosilicon compounds and a method for the preparation thereof as well as an anti-tumor agent containing the compound having very remarkable anti-tumor activity but with very low toxicity. The inventive compound is a (trihydrocarbylsilylmethyloxyimino)alkane, which is a silicon-containing oxime compound hitherto not described in any prior art literatures, represented by the general formula R.sup.1.sub.3 Si--CH.sub.2 --O--N.dbd.Y, R.sup.1 is a substituted or unsubstituted monovalent hydrocarbon group having from 1 to 10 carbon atoms and Y is a divalent hydrocarbon group denoted by .dbd.CR.sup.2 R.sup.3 or .dbd.CR.sup.4, R.sup.2 and R.sup.3, which may be identical or different, having the same meaning as R.sup.1 defined above and R.sup.4 being an alkylene group to form a ring structure jointly with the carbon atom directly bonded to the nitrogen atom. Typical examples of the compounds are: 2-(trimethylsilylmethyloxyimino) butane, 2-(trimethylsilylmethyloxyimino)propane, 2-(dimethylphenylsilylmethyloxyimino) butane and trimethylsilylmethyloxyiminocyclohexane.
摘要翻译：本发明提供了一类新颖的有机硅化合物及其制备方法以及含有非常显着的抗肿瘤活性但毒性非常低的化合物的抗肿瘤剂。本发明化合物是一种（三烃基甲硅烷基甲氧基亚氨基）烷烃，其是迄今尚未在任何现有技术文献中描述的含硅肟化合物，由通式R 13 Si-CH 2 -ON A = Y表示，R 1是取代或未取代的单价烃基， 1至10个碳原子，Y是由= CR 2 R 3或= CR 4，R 2和R 3表示的二价烃基，其可以相同或不同，具有与上述R 1相同的含义，R 4为形成环的亚烷基与与氮原子直接键合的碳原子结合。化合物的典型实例是：2-（三甲基甲硅烷基甲氧基亚氨基）丁烷，2-（三甲基甲硅烷基甲氧基亚氨基）丙烷，2-（二甲基苯基甲硅烷基甲氧基亚氨基）丁烷和三甲基甲硅烷基甲氧基亚氨基环己烷。

8. 发明授权

US4267172A Bis(triorganosilylalkyl) phosphites 失效
标题翻译：双（三有机甲硅烷基烷基）亚磷酸酯
公开(公告)号：US4267172A
公开(公告)日：1981-05-12
申请号：US78772
申请日：1979-09-25
申请人： Shigeshi Toyoshima , Ryuichi Sato , Koichi Ito , Toshio Shinohara , Masatoshi Arai
发明人： Shigeshi Toyoshima , Ryuichi Sato , Koichi Ito , Toshio Shinohara , Masatoshi Arai
IPC分类号： C08K5/00 , A01N55/10 , A61K31/695 , A61P9/12 , A61P35/00 , C07F9/02 , C07F9/141 , C08K5/5419 , A01N55/00 , C07F7/08
CPC分类号： A61K31/695 , C07F9/1415
摘要： The present invention presents a novel class of compounds bis(triorganosilylalkyl) phosphites, e.g. bis(trimethylsilylmethyl) phosphite. The compound is readily prepared by the reaction of a corresponding triorganosilyl alkanol with phosphorus trichloride or by the partial hydrolysis of a corresponding tris(triorganosilylalkyl) phosphite with an equimolar amount of water followed by distillation of the reaction mixture.The compound has a remarkable anti-transplanted tumor effectiveness as established by the test with mice as the test animals for preventing the growth of Ehrlich's cancer cells and Sarcoma 180 cells. The compound has very low toxicity when orally administrated.
摘要翻译：本发明提供了一类新颖的化合物双（三有机甲硅烷基）亚磷酸酯，例如双（三甲基甲硅烷基甲基）亚磷酸酯。通过相应的三有机甲硅烷基链烷醇与三氯化磷的反应或通过相应的三（三有机甲硅烷基烷基）亚磷酸酯与等摩尔量的水部分水解然后蒸馏反应混合物来容易地制备该化合物。该化合物具有显着的抗移植肿瘤效力，其通过用小鼠作为用于预防Ehrlich癌细胞和肉瘤180细胞生长的试验动物的试验建立。该化合物在口服时具有非常低的毒性。

9. 发明授权

US4041800A Stroke length adjusting devices 失效
标题翻译：行程长度调节装置
公开(公告)号：US4041800A
公开(公告)日：1977-08-16
申请号：US608223
申请日：1975-08-27
申请人： Ryuichi Sato , Teruo Oikawa , Masahiro Nakata
发明人： Ryuichi Sato , Teruo Oikawa , Masahiro Nakata
IPC分类号： F04B49/12 , F16C3/28 , F16H21/20 , G05G1/00
CPC分类号： F04B49/125 , F16C3/28 , F16H21/20 , Y10T74/2114
摘要： A stroke length adjusting device which can be applied to a mechanism for converting a rotary motion into a reciprocating motion is disclosed. The device comprises two oil pressure chambers communicated through a bore with each other and a crank arranged between these two oil pressure chambers. A pressure balance between the two oil pressure chambers permits the crank to displace in its axial direction so as to adjust a stroke length of the reciprocating motion.
摘要翻译：公开了一种可应用于将旋转运动转换为往复运动的机构的行程长度调节装置。该装置包括通过孔相互连通的两个油压室和布置在这两个油压室之间的曲柄。两个油压室之间的压力平衡允许曲柄在其轴向方向上移动，以便调整往复运动的行程长度。

10. 发明授权

US08657219B2 Sheet waste processing device, image forming apparatus, and sheet waste processing method 有权
标题翻译：片材废料处理装置，成像装置和片材废料处理方法
公开(公告)号：US08657219B2
公开(公告)日：2014-02-25
申请号：US11938826
申请日：2007-11-13
申请人： Ryuichi Sato
发明人： Ryuichi Sato
IPC分类号： B02C23/00 , B26D7/06
CPC分类号： B65H35/00 , B26D7/18 , B65H2301/543 , B65H2407/10 , Y10T83/2196
摘要： A sheet waste processing device includes: a sheet processing tool that generates piece-like sheet wastes by processing for sheets; a waste receiver that is provided freely movably under the sheet processing tool between a setting position where the sheet wastes generated by the sheet processing tool are housed and a non-setting position where the sheet wastes housed are disposed of; and a transporting/guarding member that is provided between the sheet processing tool and the waste receiver, transports the sheet wastes into the waste receiver located at the setting position, and blocks direct touching the sheet processing tool from a waste receiver space generated by movement of the waste receiver under the condition that the waste receiver is moved to the non-setting position.
摘要翻译：片材废料处理装置包括：片材处理工具，其通过加工片材生成片状废料; 处理在纸张处理工具之下可自由移动地设置在由片材加工工具生成的片材废弃物的设定位置和容纳片材废弃物的非固定位置之间的废弃物接收器; 以及设置在片材处理工具和废物接收器之间的运送/防护构件，将片材废物运送到位于设定位置的废物接收器中，并且阻止片材处理工具从由在废物接收器移动到非设定位置的条件下，废物接收器。

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