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1. 发明授权

US07799282B2 Sample chamber for a liquid 有权
标题翻译：用于液体的样品室
公开(公告)号：US07799282B2
公开(公告)日：2010-09-21
申请号：US10542455
申请日：2004-01-13
申请人： Johan-Valentin Kahl , Roman Zantl
发明人： Johan-Valentin Kahl , Roman Zantl
IPC分类号： B01D53/04 , B01D19/00 , B01L3/00
CPC分类号： B01L3/502723 , B01D19/0031 , B01L3/5027 , B01L3/502746 , B01L2200/0684 , B01L2300/069 , B01L2300/0822 , B01L2300/10 , B01L2400/0487
摘要： The present invention relates to a sample chamber for a liquid, wherein at least one part in the interior of the sample chamber comprises a fluid-absorbent and/or fluid-permeable plastic, which is essentially degasified in at least one area and/or in which a predetermined fluid and/or predetermined solid is stored in soluble form in at least one area.
摘要翻译：本发明涉及一种用于液体的样品室，其中样品室内部的至少一部分包括流体吸收和/或流体可渗透的塑料，其在至少一个区域和/或其中预定流体和/或预定固体以可溶形式存储在至少一个区域中。

2. 发明授权

US07582264B2 Device for microfluid analyses 有权
标题翻译：微流体分析装置
公开(公告)号：US07582264B2
公开(公告)日：2009-09-01
申请号：US10589307
申请日：2004-10-04
申请人： Johan-Valentin Kahl , Roman Zantl
发明人： Johan-Valentin Kahl , Roman Zantl
IPC分类号： B01L11/00
CPC分类号： G02B21/34 , B01L3/502753 , B01L2300/047 , B01L2300/0681 , B01L2300/0822 , G01N2001/4016 , G01N2013/003
摘要： The invention relates to a device for microfluid analyses for a substrate with plane base surface and cover surface, wherein a chamber is integrated in the substrate for receiving liquid with at least two admissions and a semipermeable or permeable membrane is arranged in the chamber, wherein the chamber is subdivided by the membrane into two sectional chambers with at least one admission each.
摘要翻译：本发明涉及一种用于具有平面基面和盖表面的基底的微流体分析装置，其中腔室集成在基底中，用于接收具有至少两次注入的液体，并且半透膜或渗透膜布置在腔室中，其中腔室被膜细分为两个分区室，每个腔室至少有一个入口。

3. 发明申请

US20060239865A1 Sample chamber for a liquid 有权
标题翻译：用于液体的样品室
公开(公告)号：US20060239865A1
公开(公告)日：2006-10-26
申请号：US10542455
申请日：2004-01-13
申请人： Johan-Valentin Kahl , Roman Zantl
发明人： Johan-Valentin Kahl , Roman Zantl
IPC分类号： B01L9/00
CPC分类号： B01L3/502723 , B01D19/0031 , B01L3/5027 , B01L3/502746 , B01L2200/0684 , B01L2300/069 , B01L2300/0822 , B01L2300/10 , B01L2400/0487
摘要： The present invention relates to a sample chamber for a liquid, wherein at least one part in the interior of the sample chamber comprises a fluid-absorbent and/or fluid-permeable plastic, which is essentially degasified in at least one area and/or in which a predetermined fluid and/or predetermined solid is stored in soluble form in at least one area.
摘要翻译：本发明涉及一种用于液体的样品室，其中样品室内部的至少一部分包括流体吸收和/或流体可渗透的塑料，其在至少一个区域和/或其中预定流体和/或预定固体以可溶形式存储在至少一个区域中。

4. 发明申请

US20100175488A1 Sample Chamber and Method for the Production Thereof 有权
标题翻译：样品室及其生产方法
公开(公告)号：US20100175488A1
公开(公告)日：2010-07-15
申请号：US11996546
申请日：2006-07-31
申请人： Johan-Valentin Kahl , Roman Zantl
发明人： Johan-Valentin Kahl , Roman Zantl
IPC分类号： B01L9/00 , B32B37/00 , H05H1/24
CPC分类号： B29C65/02 , B01J2219/00317 , B01J2219/00527 , B01J2219/00605 , B01J2219/0061 , B01J2219/00621 , B01J2219/0063 , B01J2219/00635 , B01L3/502707 , B01L3/5085 , B01L2200/0668 , B01L2200/12 , B01L2300/0636 , B01L2300/0681 , B01L2300/0822 , B01L2300/0877 , B01L2300/0887 , B01L2300/161 , B01L2300/165 , B01L2400/0406 , B01L2400/086 , B29C59/142 , B29C65/16 , B29C65/48 , B29C65/4895 , B29C66/02 , B29C66/1122 , B29C66/345 , B29C66/5342 , B29C66/53421 , B29C66/53461 , B29C66/71 , B29C66/7352 , B29C66/8322 , B29K2023/06 , B29K2023/12 , B29K2025/00 , B29K2033/12 , B29K2067/00 , B29K2069/00 , B29K2071/00 , B29K2077/00 , B29K2995/0026 , Y10T156/10 , B29K2067/003 , B29K2027/18 , B29K2023/38
摘要： The invention relates to a sample chamber with a cover plate and a bottom plate which is joined thereto in a fixed manner, wherein a recess is provided in the cover plate so that a reservoir is formed by the bottom plate, wherein a planar element with holes is provided in the reservoir, wherein the holes have a predetermined arrangement and/or size.
摘要翻译：本发明涉及具有盖板和底板的样品室，其以固定的方式连接到其上，其中在盖板中设置有凹槽，使得由底板形成储存器，其中具有孔的平面元件设置在储存器中，其中孔具有预定的布置和/或尺寸。

5. 发明授权

US08470110B2 Sample chamber and method for the production thereof 有权
标题翻译：样品室及其制备方法
公开(公告)号：US08470110B2
公开(公告)日：2013-06-25
申请号：US11996546
申请日：2006-07-31
申请人： Johan-Valentin Kahl , Roman Zantl
发明人： Johan-Valentin Kahl , Roman Zantl
IPC分类号： B01L3/00 , B29D23/00 , B29L23/00
CPC分类号： B29C65/02 , B01J2219/00317 , B01J2219/00527 , B01J2219/00605 , B01J2219/0061 , B01J2219/00621 , B01J2219/0063 , B01J2219/00635 , B01L3/502707 , B01L3/5085 , B01L2200/0668 , B01L2200/12 , B01L2300/0636 , B01L2300/0681 , B01L2300/0822 , B01L2300/0877 , B01L2300/0887 , B01L2300/161 , B01L2300/165 , B01L2400/0406 , B01L2400/086 , B29C59/142 , B29C65/16 , B29C65/48 , B29C65/4895 , B29C66/02 , B29C66/1122 , B29C66/345 , B29C66/5342 , B29C66/53421 , B29C66/53461 , B29C66/71 , B29C66/7352 , B29C66/8322 , B29K2023/06 , B29K2023/12 , B29K2025/00 , B29K2033/12 , B29K2067/00 , B29K2069/00 , B29K2071/00 , B29K2077/00 , B29K2995/0026 , Y10T156/10 , B29K2067/003 , B29K2027/18 , B29K2023/38
摘要： The invention relates to a sample chamber with a cover plate and a bottom plate which is joined thereto in a fixed manner, wherein a recess is provided in the cover plate so that a reservoir is formed by the bottom plate, wherein a planar element with holes is provided in the reservoir, wherein the holes have a predetermined arrangement and/or size.
摘要翻译：本发明涉及具有盖板和底板的样品室，其以固定的方式连接到其上，其中在盖板中设置有凹槽，使得由底板形成储存器，其中具有孔的平面元件设置在储存器中，其中孔具有预定的布置和/或尺寸。

6. 发明授权

US07204922B1 Method and device for the electrophoretic separation of particles, especially of macromolecules, by electrophoresis 失效
标题翻译：通过电泳电泳分离颗粒，特别是大分子的方法和装置
公开(公告)号：US07204922B1
公开(公告)日：2007-04-17
申请号：US10049245
申请日：1999-07-26
申请人： Johan-Valentin Kahl , Julia Nissen , Joachim Rädler , Roman Zantl , Berenike Maier , Ulf Rädler , Andres Hohner , Reinhard Galneder
发明人： Johan-Valentin Kahl , Julia Nissen , Joachim Rädler , Roman Zantl , Berenike Maier , Ulf Rädler , Andres Hohner , Reinhard Galneder
IPC分类号： G01N27/26
CPC分类号： G01N27/44773 , B01D57/02 , G01N27/44747
摘要： The present invention provides a method for the electrophoretic separation of particles, especially of macromolecules, comprising the steps of applying the particles to be separated on a substrate supported membrane, such that the particles are mobile across the surface of the substrate supported membrane; providing an electrical field such that electrical fields are formed along the surface across which the particles are mobile; and temporarily modifying the electrical field and/or adding a substrate supported membrane having a structured surface, wherein the direction and/or the strength of the electrical field are temporarily modified and/or wherein the substrate supported membrane is structured so that a force is acting on the particles that leads to a movement depending on the length of the particles. Moreover, a substrate is provided, in particular, for supporting a membrane during the performing of the inventive methods, that comprises an optically transparent material. Moreover, the invention provides a substrate supported membrane for carrying out the inventive methods including an inventive substrate as defined in the claims and a fluid lipid membrane. Moreover, the present invention provides a microchannel electrophoresis chamber having at least one channel with a bottom surface including an inventive substrate, and an electrode assembly.
摘要翻译：本发明提供了一种用于电泳分离颗粒，特别是大分子的方法，包括以下步骤：将待分离的颗粒施加在基板支撑的膜上，使得颗粒在基底支撑的膜的表面上是可移动的; 提供电场，使得沿着颗粒可移动的表面形成电场; 并临时修改电场和/或添加具有结构化表面的基底支撑膜，其中电场的方向和/或强度被暂时改变和/或其中基底支撑膜被构造成使得力作用在导致根据颗粒长度的运动的颗粒上。此外，提供了一种衬底，特别是用于在执行本发明的方法期间支撑膜，其包括光学透明材料。此外，本发明提供了一种用于实施本发明方法的底物负载膜，包括如权利要求中所定义的本发明基质和流体脂质膜。此外，本发明提供一种具有至少一个通道的微通道电泳室，底部表面包括本发明的基底和电极组件。

7. 发明授权

US10350603B2 Cover device for sample carrier 有权
公开(公告)号：US10350603B2
公开(公告)日：2019-07-16
申请号：US12352084
申请日：2009-01-12
申请人： Roman Zantl , Elias Horn
发明人： Roman Zantl , Elias Horn
IPC分类号： C12M1/22 , C12M3/00 , B01L3/00
摘要： The present invention relates to a cover device for a sample carrier, comprising a sticky surface area for connection to the sample carrier, wherein the sticky surface area is configured such that the sample carrier is covered in liquid-tight fashion after connection of the cover device to the sample carrier in the sticky surface area.

8. 发明申请

US20140141464A1 Microfluid Device and Method of Producing Diffusively Built Gradients 有权
标题翻译：微流体装置和生成扩散式梯度的方法
公开(公告)号：US20140141464A1
公开(公告)日：2014-05-22
申请号：US14101928
申请日：2013-12-10
申请人： Roman Zantl
发明人： Roman Zantl
IPC分类号： G01N1/30
CPC分类号： G01N1/30 , B01F13/0059 , B01F13/0093 , B01F15/0404 , B01L3/5025 , B01L3/502707 , B01L3/502746 , B01L3/502769 , B01L2300/0816 , B01L2300/0867 , B01L2400/0406 , B01L2400/0472 , C12Q1/34
摘要： A microfluid device for producing diffusively built gradients comprising a bottom plate and a cover plate, wherein the cover plate has recesses and is connected to the bottom plate in a liquid-tight manner so that the recesses form at least two reservoirs and one observation chamber, which connects the reservoir, a reservoir can be filled particularly through an inlet/outlet through the cover plate, and the cross-sectional surface of the observation chamber is at least 5 times, preferably at least 200 times smaller at the aperture of the observation chamber into one of the reservoirs than the maximum cross-sectional surface of the reservoir in parallel to this cross-sectional surface of the observation chamber.
摘要翻译：一种用于制造包括底板和盖板的扩散构造的梯度的微流体装置，其中所述盖板具有凹部并以液密方式连接到所述底板，使得所述凹部形成至少两个储存器和一个观察室，其连接储存器，储存器可以特别地通过盖板的入口/出口填充，并且观察室的横截面在观察室的孔口处至少是5倍，优选地至少小200倍进入与储存器的最大截面表面平行的观察室的该横截面的一个储存器。

9. 发明授权

US07934519B2 Valve unit for a microfluid system 有权
标题翻译：用于微流体系统的阀单元
公开(公告)号：US07934519B2
公开(公告)日：2011-05-03
申请号：US11943723
申请日：2007-11-21
申请人： Roman Zantl
发明人： Roman Zantl
IPC分类号： F16K11/22
CPC分类号： F16K99/0023 , B01L3/502738 , B01L2400/0622 , F16K99/0001 , F16K99/0057 , F16K2099/0084 , Y10T137/85954 , Y10T137/86067 , Y10T137/87249 , Y10T137/8741
摘要： The present invention relates to a valve unit for a microfluid system comprising a first and a second fluid reservoir, a flow chamber, a fluid channel array and a conveying means, said first fluid reservoir being, via the flow chamber, in fluidic communication with the second fluid reservoir through the fluid channel array,wherein the valve unit can be brought from a first state to a second state so that, in said first state, a fluid can be conveyed by the conveying means from said first fluid reservoir through the flow chamber in a predetermined direction of flow into the second fluid reservoir, and so that, in said second state, a fluid can be conveyed by the conveying means from said second fluid reservoir through the flow chamber in a predetermined direction of flow into the first fluid reservoir.
摘要翻译：本发明涉及一种用于微流体系统的阀单元，其包括第一和第二流体储存器，流动室，流体通道阵列和输送装置，所述第一流体储存器经由流动室与流体连通通过所述流体通道阵列的第二流体储存器，其中所述阀单元可以从第一状态转到第二状态，使得在所述第一状态下，流体可以由所述输送装置从所述第一流体储存器通过所述流动室输送在流入第二流体储存器的预定方向上，并且使得在所述第二状态下，流体可以通过输送装置从所述第二流体储存器通过流动室以预定的流动方向输送到第一流体储存器。

10. 发明授权

US09915593B2 Method of positioning an organic, biological and/or medical specimen 有权
公开(公告)号：US09915593B2
公开(公告)日：2018-03-13
申请号：US12777558
申请日：2010-05-11
申请人： Roman Zantl , Elias Horn
发明人： Roman Zantl , Elias Horn
IPC分类号： G01N1/36
CPC分类号： G01N1/36
摘要： The invention relates to a method of positioning an organic, biological and/or medical specimen in a desired partial region of a specimen carrier, comprising the steps arrangement of a gel in a partial region of the specimen carrier, polymerization or gelification of the gel, by means of which a polymerized gel is obtained, whereby the polymerized gel at least partially, in particular horizontally, delimits the desired partial region and introduction of the specimen into the specimen carrier, in particular into the desired partial region of the specimen carrier.

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