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1. 发明授权

US06956202B2 Method and device for calibrating an image pick-up device sensitive to magnetic fields and for imaging by means of such an image pick-up device 失效
标题翻译：用于校准对磁场敏感并通过这种图像拾取装置进行成像的图像拾取装置的方法和装置
公开(公告)号：US06956202B2
公开(公告)日：2005-10-18
申请号：US10294351
申请日：2002-11-13
申请人： Joerg Sabczynski , Waldemar Zylka
发明人： Joerg Sabczynski , Waldemar Zylka
IPC分类号： G01T1/00 , A61B6/00 , G01T1/17 , G01T7/00 , G06T5/00 , H04N5/32 , H04N5/335 , G01D18/00
CPC分类号： A61B6/583 , A61B6/4441
摘要： A description is given of a method and a device for the calibration of an image pick-up device which is sensitive to magnetic fields and for the imaging by means of such an image pick-up device. The image pick-up device is notably an image intensifier in X-ray systems such as, for example, systems provided with a C-arm. Calibration is performed essentially by forming and storing a look-up table whereby a plurality of magnetic field data acting on the image pick-up device is associated with calibration data required for correcting the distortions caused thereby. During imaging, the magnetic field data acting on the image pick-up device during the formation of an image is measured and the calibration data associated with this magnetic field data in the table is read out and used for the correction of the acquired image.
摘要翻译：给出了对磁场敏感的图像拾取装置的校准方法和装置以及借助于这种图像拾取装置进行成像的装置。图像拾取装置尤其是X射线系统中的图像增强器，例如具有C形臂的系统。基本上通过形成和存储查找表来执行校准，由此，作用在图像拾取装置上的多个磁场数据与校正由此引起的失真所需的校准数据相关联。在成像期间，测量在形成图像期间作用在图像拾取装置上的磁场数据，并且读出与该表中的该磁场数据相关联的校准数据，并用于校正所获取的图像。

2. 发明授权

US06739752B2 Method and device for calibrating a gravity-sensitive image pick-up device and for imaging by means of such an image pick-up device 失效
标题翻译：用于校准重力敏感图像拾取装置并通过这种图像拾取装置进行成像的方法和装置
公开(公告)号：US06739752B2
公开(公告)日：2004-05-25
申请号：US10294293
申请日：2002-11-14
申请人： Joerg Sabczynski , Waldemar Zylka
发明人： Joerg Sabczynski , Waldemar Zylka
IPC分类号： G01D1800
CPC分类号： A61B6/583 , A61B6/4441 , G06T5/006
摘要： A description is given of a method and a device for the calibration of an image pick-up device which is sensitive to gravity. Also described are a method and a device for imaging by means of such an image pick-up device; they are used in particular in X-ray systems, for example, systems provided with a C-arm. Calibration is performed essentially by forming and storing a look-up table whereby the calibration data required for the correction of distortions due to the supporting construction is associated with a plurality of position data of the supporting construction. During imaging the direction of the force of gravity relative to the supporting construction is measured; therefrom the position data is calculated and the calibration data associated with this data in the table is read out and used for the correction of the acquired image.
摘要翻译：给出了对重力敏感的图像拾取装置的校准方法和装置的描述。还描述了通过这种图像拾取装置进行成像的方法和装置; 它们特别用于X射线系统，例如具有C臂的系统。基本上通过形成和存储查找表来执行校准，由此由于支撑结构而校正失真所需的校准数据与支撑结构的多个位置数据相关联。在成像期间测量重力相对于支撑结构的方向; 从而计算位置数据，并且读出与表中的该数据相关联的校准数据，并用于校正所获取的图像。

3. 发明授权

US08983575B2 Device and method for the determination of the position of a catheter in a vascular system 有权
标题翻译：用于确定导管在血管系统中的位置的装置和方法
公开(公告)号：US08983575B2
公开(公告)日：2015-03-17
申请号：US10597984
申请日：2005-02-18
申请人： Sascha Krueger , Holger Timinger , Joerg Sabczynski , Joern Borgert
发明人： Sascha Krueger , Holger Timinger , Joerg Sabczynski , Joern Borgert
IPC分类号： A61B5/05 , A61B5/06 , A61B19/00 , A61B6/12
CPC分类号： A61B5/06 , A61B5/062 , A61B6/12 , A61B34/20 , A61B90/36 , A61B2034/2051 , A61B2090/3958
摘要： The invention relates to a device and a method for the determination of the position of a catheter in a vascular system (8). In this, the measured positions (r1, r2) of two magnetic localizers at the tip of a catheter are displaced by correction vectors (k1, k2) while optimizing a quality dimension. The quality dimension includes a component taking account both of the deviation of the measured positions (r1, r2) from the vascular layout and of the deviation of the associated orientation (r2−r1) from the orientation of the vascular layout according to a vascular map. In addition, the quality dimension may include components which evaluate the measured shape of the catheter compared to the vascular map. An additional correction step can further ensure that the corrected positions (r1′, r2″) correspond to the preset fixed distance (d) of the localizers (4, 5).
摘要翻译：本发明涉及一种用于确定导管在血管系统（8）中的位置的装置和方法。在此，在优化质量维度的同时，通过校正矢量（k1，k2）使导管尖端处的两个定位器的测量位置（r1，r2）移位。质量维度包括考虑到血管布局的测量位置（r1，r2）的偏差和相关联取向（r2-r1）与血管布局的取向（根据血管图）的偏差的分量。此外，质量维度可以包括与血管图相比评估导管的测量形状的组件。附加的校正步骤还可以确保校正位置（r1'，r2“）对应于定位器（4,5）的预设固定距离（d）。

4. 发明申请

US20110124976A1 MODEL ENHANCED IMAGING 审中-公开
标题翻译：模型增强成像
公开(公告)号：US20110124976A1
公开(公告)日：2011-05-26
申请号：US13055792
申请日：2009-07-22
申请人： Joerg Sabczynski , Steffen Renisch , Ingwer-Curt Carlsen , Sven Kabus , Roland Opfer , Michael Kaus , Karl Antonin Bzdusek , Juergen Weese , Vladimir Pekar
发明人： Joerg Sabczynski , Steffen Renisch , Ingwer-Curt Carlsen , Sven Kabus , Roland Opfer , Michael Kaus , Karl Antonin Bzdusek , Juergen Weese , Vladimir Pekar
IPC分类号： A61B5/00 , G06G7/60
CPC分类号： G06F19/3481 , A61B2034/105 , A61B2090/374 , A61B2090/3762 , A61N5/103 , A61N7/02 , A61N2005/1041 , G06F19/321 , G06F19/324 , G16H10/60 , G16H50/20 , G16H50/50
摘要： A therapy treatment response simulator includes a modeler (202) that generates a model of a structure of an object or subject based on information about the object or subject and a predictor (204) that generates a prediction indicative of how the structure is likely to respond to treatment based on the model and a therapy treatment plan. In another aspect, a system includes performing a patient state determining in silico simulation for a patient using a candidate set of parameters corresponding to another patient and producing a first signal indicative of a predicted state of the patient, and generating a second signal indicative of whether the candidate set of parameters are suitable for the patient based on a known state of the patient.
摘要翻译：治疗治疗反应模拟器包括基于关于对象或对象的信息生成对象或对象的结构的模型的建模器（202），以及生成表示结构如何响应的预测的预测器（204）基于模型治疗和治疗方案。在另一方面，一种系统包括使用与另一患者相对应的参数的候选组来执行患者状态的计算机模拟，并产生指示患者的预测状态的第一信号，以及产生指示是否基于患者的已知状态，候选参数组合适合于患者。

5. 发明申请

US20120123801A1 PET/CT BASED MONITORING SYSTEM SUPPORTED BY A CLINICAL GUIDELINE NAVIGATOR 审中-公开
标题翻译：基于PET / CT的监测系统由临床导向导管支持
公开(公告)号：US20120123801A1
公开(公告)日：2012-05-17
申请号：US13260533
申请日：2010-02-11
申请人： Roland Opfer , Lilla Boroczky , Ingwer Curt Carlsen , Pradyumna Dutta , Steffen Renisch , Joerg Sabczynski , Paola Karina Tulipano
发明人： Roland Opfer , Lilla Boroczky , Ingwer Curt Carlsen , Pradyumna Dutta , Steffen Renisch , Joerg Sabczynski , Paola Karina Tulipano
IPC分类号： G06Q50/24
CPC分类号： G16H10/60 , A61B6/037 , A61B6/508 , G06F19/00 , G06F19/321 , G06Q50/24
摘要： An oncology monitoring system comprises: an image analysis module (42, 44) configured to perform an oncological monitoring operation based on images of a subject, for example acquired by positron emission tomography (PET) and computed tomography (CT); and a clinical guideline support module (10). The clinical guideline support module is configured to: display a graphical flow diagram (GFD) of a clinical therapy protocol for treating the subject comprising graphical blocks (B0, B1 B2, B3, B4, B5, B21, B211, B22, B221, B222, B223, B23, B231, B232) representing therapeutic or monitoring operations of the clinical therapy protocol including at least one monitoring operation performed by the image analysis module; annotate a graphical block of the graphical flow diagram with subject-specific information pertaining to a therapeutic or monitoring operation represented by the graphical block; and display an annotation (POP) of a graphical block (B211) responsive to selection of the graphical block by a user.
摘要翻译：肿瘤监测系统包括：图像分析模块（42,44），其被配置为基于例如通过正电子发射断层摄影（PET）和计算机断层摄影（CT）获取的对象的图像执行肿瘤监测操作; 和临床指南支持模块（10）。临床指南支持模块被配置为：显示用于治疗受试者的临床治疗方案的图形流程图（GFD），包括图形块（B0，B1B2，B3，B4，B5，B21，B211，B22，B221，B222 ，B223，B23，B231，B232），其代表包括图像分析模块执行的至少一个监视操作的临床治疗方案的治疗或监视操作; 注释图形流程图的图形块，其具有与由图形块表示的治疗或监视操作有关的主题特定信息; 以及响应于用户对所述图形块的选择来显示图形块（B211）的注释（POP）。

6. 发明申请

US20230133142A1 PATIENT STRATIFICATION AND CLINICAL DECISION SUPPORT ON MECHANICAL VENTILATION SETTINGS FROM SONAR RESPONSES THROUGH AN ENDOTRACHEAL TUBE (ETT) 有权
公开(公告)号：US20230133142A1
公开(公告)日：2023-05-04
申请号：US17960167
申请日：2022-10-05
申请人： Rafael Wiemker , Joerg Sabczynski , Thomas Koehler , Cornelis Petrus Hendriks , Roberto Buizza , Jaap Roger Haartsen , Stefan Winter , Michael Polkey , Rita Priori , Nataly Wieberneit , Kiran Hamilton J. Dellimore
发明人： Rafael Wiemker , Joerg Sabczynski , Thomas Koehler , Cornelis Petrus Hendriks , Roberto Buizza , Jaap Roger Haartsen , Stefan Winter , Michael Polkey , Rita Priori , Nataly Wieberneit , Kiran Hamilton J. Dellimore
IPC分类号： A61M16/00 , A61M16/04
摘要： A respiration monitoring device comprises an electronic controller configured to: receive an audio signal that is acoustically coupled with an airway of a patient receiving mechanical ventilation therapy from a mechanical ventilator; map the audio signal to one or more lung disease or injury condition categories; and at least one of: display the mapped one or more lung disease or injury condition categories on a display device; and determine a recommended adjustment to one or more parameters of the mechanical ventilation therapy delivered to the patient based at least on the mapped lung disease or injury condition categories and displaying the recommended adjustment on the display device.

7. 发明申请

US20120089014A1 METHOD AND APPARATUS FOR TRACKING IN A MEDICAL PROCEDURE 审中-公开
标题翻译：用于跟踪医疗程序的方法和装置
公开(公告)号：US20120089014A1
公开(公告)日：2012-04-12
申请号：US13378175
申请日：2010-05-17
申请人： Joerg Sabczynski , Heinrich Schulz
发明人： Joerg Sabczynski , Heinrich Schulz
IPC分类号： A61B5/05
CPC分类号： A61B1/05 , A61B1/2676 , A61B5/0013 , A61B5/055 , A61B5/06 , A61B5/067 , A61B6/4441 , A61B6/5247 , A61B8/12 , A61B34/20 , A61B90/36 , A61B90/37 , A61B2034/2048 , A61B2090/364 , A61B2562/0219
摘要： A tracking system for a target anatomy of a patient can include a medical device having a body (281) having a distal end (290) and at least one channel (292) formed therein, where the body is adapted for insertion through an anatomy (105) to reach a target area (430); an accelerometer (185) connected to the body and positioned in proximity to the distal end; an imaging device (295) operably coupled with the body; and a light source (297) operably coupled with the body, where the accelerometer is in communication with a remote processor (120) for transmitting acceleration data thereto, where the imaging device is in communication with the remote processor for transmitting real-time images thereto, and where an orientation of the medical device with respect to the anatomy is determined by the processor based on the acceleration data.
摘要翻译：用于患者的目标解剖结构的跟踪系统可以包括具有主体（281）的医疗装置，所述主体具有远端（290）和形成在其中的至少一个通道（292），其中身体适于插入解剖结构 105）到达目标区域（430）; 加速度计（185），其连接到所述主体并且定位在所述远端附近; 与主体可操作地联接的成像装置（295）; 以及与所述主体可操作地耦合的光源（297），其中所述加速度计与用于向其传送加速度数据的远程处理器（120）通信，其中所述成像设备与所述远程处理器通信，用于向其发送实时图像并且其中医疗装置相对于解剖结构的取向由处理器基于加速度数据确定。

8. 发明申请

US20110286652A1 SYSTEM FOR PROVIDING LUNG VENTILATION INFORMATION 有权
标题翻译：提供肺通气信息的系统
公开(公告)号：US20110286652A1
公开(公告)日：2011-11-24
申请号：US13146885
申请日：2010-01-25
申请人： Sven Kabus , Cristian Lorenz , Nicole Schadewaldt , Roland Opfer , Ingwer Curt Carlsen , Steffen Renisch , Joerg Sabczynski , Hans Barschdorf , Jens Von Berg , Thomas Blaffert , Tobias Klinder
发明人： Sven Kabus , Cristian Lorenz , Nicole Schadewaldt , Roland Opfer , Ingwer Curt Carlsen , Steffen Renisch , Joerg Sabczynski , Hans Barschdorf , Jens Von Berg , Thomas Blaffert , Tobias Klinder
IPC分类号： G06K9/00
CPC分类号： A61B6/5235 , A61B5/08 , A61B6/541 , G06T7/33 , G06T2207/10081 , G06T2207/30061
摘要： A system for displaying lung ventilation information, the system comprising an input (12) and a processing unit (15). The input being provided for receiving multiple CT images (71) of a lung, each CT image (71) corresponding to one phase of at least two different phases in a respiratory cycle. The processing unit (15) being configured to compare CT images (71) corresponding to different phases in the respiratory cycle for determining a deformation vector field for each phase, to generate for each phase a ventilation image (72) based on the corresponding deformation vector field, to spatially align the ventilation images (72), and to generate for at least one common position (62) in each one of the aligned ventilation images (72), a function (81) of a time course of a ventilation value for said common position (62), each ventilation value in the function (81) being based on the deformation vector fields corresponding to the aligned ventilation images (73).
摘要翻译：一种用于显示肺通气信息的系统，所述系统包括输入（12）和处理单元（15）。所述输入被提供用于接收肺的多个CT图像（71），每个CT图像（71）对应于呼吸周期中的至少两个不同相的一个相。所述处理单元（15）被配置为比较对应于呼吸周期中的不同相位的CT图像（71），以确定每个相位的变形矢量场，以根据相应的变形矢量为每个阶段生成通气图像（72）在空间上对准通气图像（72），并且为每个对齐的通气图像（72）中的至少一个公共位置（62）产生一个通风值的时间过程的功能（81），用于所述公共位置（62）中，所述功能（81）中的每个换气值基于对应于对齐的通气图像（73）的变形矢量场。

9. 发明授权

US10311971B2 PET/CT based monitoring system supported by a clinical guideline navigator 有权
公开(公告)号：US10311971B2
公开(公告)日：2019-06-04
申请号：US13260533
申请日：2010-02-11
申请人： Roland Johannes Opfer , Lilla Boroczky , Ingwer Curt Carlsen , Pradyumna Dutta , Steffen Renisch , Joerg Sabczynski , Paola Karina Tulipano
发明人： Roland Johannes Opfer , Lilla Boroczky , Ingwer Curt Carlsen , Pradyumna Dutta , Steffen Renisch , Joerg Sabczynski , Paola Karina Tulipano
IPC分类号： G16H30/20 , G16H20/40 , A61B6/03 , G06F19/00 , G06Q50/24 , G16H10/60 , A61B6/00
摘要： An oncology monitoring system comprises: an image analysis module (42, 44) configured to perform an oncological monitoring operation based on images of a subject, for example acquired by positron emission tomography (PET) and computed tomography (CT); and a clinical guideline support module (10). The clinical guideline support module is configured to: display a graphical flow diagram (GFD) of a clinical therapy protocol for treating the subject comprising graphical blocks (B0, B1, B2, B3, B4, B5, B21, B211, B22, B221, B222, B223, B23, B231, B232) representing therapeutic or monitoring operations of the clinical therapy protocol including at least one monitoring operation performed by the image analysis module; annotate a graphical block of the graphical flow diagram with subject-specific information pertaining to a therapeutic or monitoring operation represented by the graphical block; and display an annotation (POP) of a graphical block (B211) responsive to selection of the graphical block by a user.

10. 发明授权

US08798343B2 System for providing lung ventilation information 有权
标题翻译：提供肺通气信息的系统
公开(公告)号：US08798343B2
公开(公告)日：2014-08-05
申请号：US13146885
申请日：2010-01-25
申请人： Sven Kabus , Cristian Lorenz , Nicole Schadewaldt , Roland Opfer , Ingwer Curt Carlsen , Steffen Renisch , Joerg Sabczynski , Hans Barschdorf , Jens Von Berg , Thomas Blaffert , Tobias Klinder
发明人： Sven Kabus , Cristian Lorenz , Nicole Schadewaldt , Roland Opfer , Ingwer Curt Carlsen , Steffen Renisch , Joerg Sabczynski , Hans Barschdorf , Jens Von Berg , Thomas Blaffert , Tobias Klinder
IPC分类号： G06K9/00
CPC分类号： A61B6/5235 , A61B5/08 , A61B6/541 , G06T7/33 , G06T2207/10081 , G06T2207/30061
摘要： A system for displaying lung ventilation information, the system comprising an input (12) and a processing unit (15). The input being provided for receiving multiple CT images (71) of a lung, each CT image (71) corresponding to one phase of at least two different phases in a respiratory cycle. The processing unit (15) being configured to compare CT images (71) corresponding to different phases in the respiratory cycle for determining a deformation vector field for each phase, to generate for each phase a ventilation image (72) based on the corresponding deformation vector field, to spatially align the ventilation images (72), and to generate for at least one common position (62) in each one of the aligned ventilation images (72), a function (81) of a time course of a ventilation value for said common position (62), each ventilation value in the function (81) being based on the deformation vector fields corresponding to the aligned ventilation images (73).
摘要翻译：一种用于显示肺通气信息的系统，所述系统包括输入（12）和处理单元（15）。所述输入被提供用于接收肺的多个CT图像（71），每个CT图像（71）对应于呼吸周期中的至少两个不同相的一个相。所述处理单元（15）被配置为比较对应于呼吸周期中的不同相位的CT图像（71），以确定每个相位的变形矢量场，以根据相应的变形矢量为每个阶段生成通气图像（72）在空间上对准通气图像（72），并且为每个对齐的通气图像（72）中的至少一个公共位置（62）产生功能（81），其中通风值的时间过程为所述公共位置（62）中，所述功能（81）中的每个换气值基于对应于对齐的通气图像（73）的变形矢量场。

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