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1. 发明申请

US20110286652A1 SYSTEM FOR PROVIDING LUNG VENTILATION INFORMATION 有权
标题翻译：提供肺通气信息的系统
公开(公告)号：US20110286652A1
公开(公告)日：2011-11-24
申请号：US13146885
申请日：2010-01-25
申请人： Sven Kabus , Cristian Lorenz , Nicole Schadewaldt , Roland Opfer , Ingwer Curt Carlsen , Steffen Renisch , Joerg Sabczynski , Hans Barschdorf , Jens Von Berg , Thomas Blaffert , Tobias Klinder
发明人： Sven Kabus , Cristian Lorenz , Nicole Schadewaldt , Roland Opfer , Ingwer Curt Carlsen , Steffen Renisch , Joerg Sabczynski , Hans Barschdorf , Jens Von Berg , Thomas Blaffert , Tobias Klinder
IPC分类号： G06K9/00
CPC分类号： A61B6/5235 , A61B5/08 , A61B6/541 , G06T7/33 , G06T2207/10081 , G06T2207/30061
摘要： A system for displaying lung ventilation information, the system comprising an input (12) and a processing unit (15). The input being provided for receiving multiple CT images (71) of a lung, each CT image (71) corresponding to one phase of at least two different phases in a respiratory cycle. The processing unit (15) being configured to compare CT images (71) corresponding to different phases in the respiratory cycle for determining a deformation vector field for each phase, to generate for each phase a ventilation image (72) based on the corresponding deformation vector field, to spatially align the ventilation images (72), and to generate for at least one common position (62) in each one of the aligned ventilation images (72), a function (81) of a time course of a ventilation value for said common position (62), each ventilation value in the function (81) being based on the deformation vector fields corresponding to the aligned ventilation images (73).
摘要翻译：一种用于显示肺通气信息的系统，所述系统包括输入（12）和处理单元（15）。所述输入被提供用于接收肺的多个CT图像（71），每个CT图像（71）对应于呼吸周期中的至少两个不同相的一个相。所述处理单元（15）被配置为比较对应于呼吸周期中的不同相位的CT图像（71），以确定每个相位的变形矢量场，以根据相应的变形矢量为每个阶段生成通气图像（72）在空间上对准通气图像（72），并且为每个对齐的通气图像（72）中的至少一个公共位置（62）产生一个通风值的时间过程的功能（81），用于所述公共位置（62）中，所述功能（81）中的每个换气值基于对应于对齐的通气图像（73）的变形矢量场。

2. 发明授权

US08798343B2 System for providing lung ventilation information 有权
标题翻译：提供肺通气信息的系统
公开(公告)号：US08798343B2
公开(公告)日：2014-08-05
申请号：US13146885
申请日：2010-01-25
申请人： Sven Kabus , Cristian Lorenz , Nicole Schadewaldt , Roland Opfer , Ingwer Curt Carlsen , Steffen Renisch , Joerg Sabczynski , Hans Barschdorf , Jens Von Berg , Thomas Blaffert , Tobias Klinder
发明人： Sven Kabus , Cristian Lorenz , Nicole Schadewaldt , Roland Opfer , Ingwer Curt Carlsen , Steffen Renisch , Joerg Sabczynski , Hans Barschdorf , Jens Von Berg , Thomas Blaffert , Tobias Klinder
IPC分类号： G06K9/00
CPC分类号： A61B6/5235 , A61B5/08 , A61B6/541 , G06T7/33 , G06T2207/10081 , G06T2207/30061
摘要： A system for displaying lung ventilation information, the system comprising an input (12) and a processing unit (15). The input being provided for receiving multiple CT images (71) of a lung, each CT image (71) corresponding to one phase of at least two different phases in a respiratory cycle. The processing unit (15) being configured to compare CT images (71) corresponding to different phases in the respiratory cycle for determining a deformation vector field for each phase, to generate for each phase a ventilation image (72) based on the corresponding deformation vector field, to spatially align the ventilation images (72), and to generate for at least one common position (62) in each one of the aligned ventilation images (72), a function (81) of a time course of a ventilation value for said common position (62), each ventilation value in the function (81) being based on the deformation vector fields corresponding to the aligned ventilation images (73).
摘要翻译：一种用于显示肺通气信息的系统，所述系统包括输入（12）和处理单元（15）。所述输入被提供用于接收肺的多个CT图像（71），每个CT图像（71）对应于呼吸周期中的至少两个不同相的一个相。所述处理单元（15）被配置为比较对应于呼吸周期中的不同相位的CT图像（71），以确定每个相位的变形矢量场，以根据相应的变形矢量为每个阶段生成通气图像（72）在空间上对准通气图像（72），并且为每个对齐的通气图像（72）中的至少一个公共位置（62）产生功能（81），其中通风值的时间过程为所述公共位置（62）中，所述功能（81）中的每个换气值基于对应于对齐的通气图像（73）的变形矢量场。

3. 发明授权

US08526697B2 Apparatus for segmenting an object comprising sub-objects 有权
标题翻译：用于分割包括子对象的对象的装置
公开(公告)号：US08526697B2
公开(公告)日：2013-09-03
申请号：US12867522
申请日：2009-02-06
申请人： Thomas Blaffert , Hans Barschdorf , Jens Von Berg , Sebastian Peter Michael Dries , Cristian Lorenz , Rafael Wiemker , Tobias Klinder , Astrid Ruth Franz , Steffen Renisch
发明人： Thomas Blaffert , Hans Barschdorf , Jens Von Berg , Sebastian Peter Michael Dries , Cristian Lorenz , Rafael Wiemker , Tobias Klinder , Astrid Ruth Franz , Steffen Renisch
IPC分类号： G06K9/00
CPC分类号： G06T5/003 , G06T7/11 , G06T7/149 , G06T2207/10081 , G06T2207/20041 , G06T2207/20081 , G06T2207/20124 , G06T2207/20192 , G06T2207/30061
摘要： The present invention relates to an apparatus (1) for segmenting an object comprising sub-objects shown in an object image. The apparatus comprises a feature image generation unit (2) for generating a feature image showing features related to intermediate regions between the sub-objects and a segmentation unit (3) for segmenting the sub-objects by using the object image and the feature image. Preferentially, the feature image generation unit (2) is adapted for generating a feature image from the object image. In a further embodiment, the feature image generation unit (2) comprises a feature enhancing unit for enhancing features related to intermediate regions between the sub-objects in the object image.
摘要翻译：本发明涉及一种用于分割包含物体图像中所示的子对象的物体的装置（1）。该装置包括：特征图像生成单元，用于生成显示与子对象之间的中间区域相关的特征的特征图像和用于通过使用对象图像和特征图像来分割子对象的分割单元（3）。优选地，特征图像生成单元（2）适于从对象图像生成特征图像。在另一实施例中，特征图像生成单元（2）包括特征增强单元，用于增强与对象图像中的子对象之间的中间区域相关的特征。

4. 发明申请

US20110052018A1 APPARATUS FOR SEGMENTING AN OBJECT COMPRISING SUB-OBJECTS 有权
标题翻译：用于分配包含子对象的对象的设备
公开(公告)号：US20110052018A1
公开(公告)日：2011-03-03
申请号：US12867522
申请日：2009-02-06
申请人： Thomas Blaffert , Hans Barschdorf , Jans Von Berg , Sebastian Peter Michael Dries , Cristian Lorenz , Rafael Wiemker , Tobias Klinder , Astrid Ruth Franz , Steffen Renisch
发明人： Thomas Blaffert , Hans Barschdorf , Jans Von Berg , Sebastian Peter Michael Dries , Cristian Lorenz , Rafael Wiemker , Tobias Klinder , Astrid Ruth Franz , Steffen Renisch
IPC分类号： G06K9/00 , G06K9/34
CPC分类号： G06T5/003 , G06T7/11 , G06T7/149 , G06T2207/10081 , G06T2207/20041 , G06T2207/20081 , G06T2207/20124 , G06T2207/20192 , G06T2207/30061
摘要： The present invention relates to an apparatus (1) for segmenting an object comprising sub-objects shown in an object image. The apparatus comprises a feature image generation unit (2) for generating a feature image showing features related to intermediate regions between the sub-objects and a segmentation unit (3) for segmenting the sub-objects by using the object image and the feature image. Preferentially, the feature image generation unit (2) is adapted for generating a feature image from the object image. In a further embodiment, the feature image generation unit (2) comprises a feature enhancing unit for enhancing features related to intermediate regions between the sub-objects in the object image.
摘要翻译：本发明涉及一种用于分割包含物体图像中所示的子对象的物体的装置（1）。该装置包括：特征图像生成单元，用于生成显示与子对象之间的中间区域相关的特征的特征图像和用于通过使用对象图像和特征图像来分割子对象的分割单元（3）。优选地，特征图像生成单元（2）适于从对象图像生成特征图像。在另一实施例中，特征图像生成单元（2）包括特征增强单元，用于增强与对象图像中的子对象之间的中间区域相关的特征。

5. 发明授权

US08233691B2 Reduction of heart motion artifacts in thoracic CT imaging 有权
标题翻译：减少胸部CT成像中的心脏运动伪影
公开(公告)号：US08233691B2
公开(公告)日：2012-07-31
申请号：US12438952
申请日：2007-08-27
申请人： Hans Barschdorf , Jens Von Berg , Michael Harald Kuhn , Cristian Lorenz , Thomas Blaffert
发明人： Hans Barschdorf , Jens Von Berg , Michael Harald Kuhn , Cristian Lorenz , Thomas Blaffert
IPC分类号： G06K9/00
CPC分类号： G06T7/251 , G06T7/149 , G06T7/33 , G06T2200/04 , G06T2207/10081 , G06T2207/30048 , G06T2207/30061 , G06T2211/412
摘要： The invention relates to a system for adapting a plurality of model meshes to a plurality of image data. The system has a registration unit for registering the plurality of model meshes with the plurality of image data on the basis of a computation of a registration transformation for transforming the plurality of model meshes, and an adaptation unit for adapting the plurality of registered model meshes to the plurality of image data on the basis of a computation of locations of mesh vertices of the plurality of model meshes. The described system is capable of reducing motion artifacts in tomographic images computed from data acquired at a plurality of different cardiac cycle phases.
摘要翻译：本发明涉及一种用于将多个模型网格适配成多个图像数据的系统。该系统具有注册单元，用于基于用于变换多个模型网格的注册变换的计算，将多个模型网格注册到多个图像数据;以及适配单元，用于将多个注册模型网格适配到基于多个模型网格的网格顶点的位置的计算来生成多个图像数据。所描述的系统能够减少从在多个不同的心动周期阶段获取的数据计算的断层图像中的运动伪像。

6. 发明申请

US20100014736A1 REDUCTION OF HEART MOTION ARTIFACTS IN THORACIC CT IMAGING 有权
标题翻译：减少心脏CT成像中心脏运动的影响
公开(公告)号：US20100014736A1
公开(公告)日：2010-01-21
申请号：US12438952
申请日：2007-08-27
申请人： Hans Barschdorf , Jens Von Berg , Michael Harald Kuhn , Cristian Lorenz , Thomas Blaffert
发明人： Hans Barschdorf , Jens Von Berg , Michael Harald Kuhn , Cristian Lorenz , Thomas Blaffert
IPC分类号： G06K9/32 , G06K9/00
CPC分类号： G06T7/251 , G06T7/149 , G06T7/33 , G06T2200/04 , G06T2207/10081 , G06T2207/30048 , G06T2207/30061 , G06T2211/412
摘要： The invention relates to a system (100) for adapting a plurality of model meshes to a plurality of image data, the system comprising a registration unit (110) for registering the plurality of model meshes with the plurality of image data on the basis of a computation of a registration transformation for transforming the plurality of model meshes, and an adaptation unit (120) for adapting the plurality of registered model meshes to the plurality of image data on the basis of a computation of locations of mesh vertices of the plurality of model meshes. The system (100) may further comprise a computing unit (130) for computing sparse vector fields comprising vectors of displacements of vertices of the adapted model meshes, an approximation unit (140) for computing dense vector fields on the basis of the sparse vector fields, a merge unit (150) for merging image data sets by means of the computed dense vector fields, and a reconstruction unit (155) for reconstructing a motion-compensated image data from the computed dense vector fields. The described system (100) is capable of reducing motion artifacts in tomographic images computed from data acquired at a plurality of different cardiac cycle phases.
摘要翻译：本发明涉及一种用于将多个模型网格适配到多个图像数据的系统（100），该系统包括：注册单元（110），用于基于多个图像数据登记多个模型网格与多个图像数据用于变换多个模型网格的注册变换的计算;以及适应单元，用于根据多个模型的网格顶点的位置的计算来将多个注册模型网格适配到多个图像数据网格系统（100）还可以包括计算单元（130），用于计算包括适应模型网格的顶点位移矢量的稀疏矢量场，用于基于稀疏矢量场计算密集矢量场的近似单元（140），用于通过所计算的密集矢量场合并图像数据组的合并单元（150），以及用于从所计算的密集矢量场重构运动补偿图像数据的重建单元（155）。所描述的系统（100）能够减少从在多个不同的心动周期阶段获取的数据计算的断层图像中的运动伪影。

7. 发明申请

US20110169864A1 PATIENT SPECIFIC ANATIOMICAL SKETCHES FOR MEDICAL REPORTS 审中-公开
标题翻译：患者特殊用途医疗报告草图
公开(公告)号：US20110169864A1
公开(公告)日：2011-07-14
申请号：US13120181
申请日：2009-09-17
申请人： Cristian Lorenz , Sebastian Peter Michael Dries , Steffen Renisch , Jens Von Berg
发明人： Cristian Lorenz , Sebastian Peter Michael Dries , Steffen Renisch , Jens Von Berg
IPC分类号： G09G5/00
CPC分类号： G06F19/3487 , G06F19/00 , G06F19/321 , G06T7/0012 , G06T7/12 , G06T7/149 , G06T19/20 , G06T2207/10072 , G06T2207/10116 , G06T2207/30012 , G06T2219/2021 , G16H15/00
摘要： The invention relates to a system (100) for producing a representation of an object in image data, based on a template coupled to a model of the object, the system comprising a model unit for adapting the model to the object in the image data, and a template unit for adapting the template to the adapted model on the basis of the coupling between the template and the model. The template defines a representation of the object which is simpler to interpret than the model. The template may be arranged to emphasize useful features of the object. The template comprises substantially fewer degrees of freedom and thus can be efficiently adapted to the model. Because the template of the invention is coupled to the model, the position, orientation and/or shape of the template is determined by the model adapted to the object in the image data. Hence, the template is adapted to the image data. The adapted template is capable of representing the object and its individual characteristics, e.g., the shape of the object as well as the position and/or orientation of the object with respect to an external reference system defined, e.g., based on the image data.
摘要翻译：本发明涉及一种用于基于耦合到对象的模型的模板来产生图像数据中的对象的表示的系统（100），该系统包括用于将模型适配到图像数据中的对象的模型单元，以及模板单元，用于基于模板和模型之间的耦合来将模板适配到适配模型。模板定义了比模型更简单的对象的表示。模板可以被布置为强调对象的有用特征。该模板包括基本上更少的自由度，因此可以有效地适应于该模型。因为本发明的模板耦合到模型，所以模板的位置，取向和/或形状由适于图像数据中的对象的模型确定。因此，该模板适合图像数据。适应的模板能够表示对象及其各自的特征，例如对象的形状以及对象相对于例如基于图像数据定义的外部参考系统的位置和/或取向。

8. 发明授权

US10102347B2 Patient specific anatiomical sketches for medical reports 有权
公开(公告)号：US10102347B2
公开(公告)日：2018-10-16
申请号：US13120181
申请日：2009-09-17
申请人： Cristian Lorenz , Sebastian Peter Michael Dries , Steffen Renisch , Jens Von Berg
发明人： Cristian Lorenz , Sebastian Peter Michael Dries , Steffen Renisch , Jens Von Berg
IPC分类号： G06F19/00 , G06T7/00 , G06T19/20 , G06T7/12 , G06T7/149 , G16H15/00
摘要： The invention relates to a system for producing a representation of an object in image data, based on a template coupled to a model of the object, the system comprising a model unit for adapting the model to the object in the image data, and a template unit for adapting the template to the adapted model on the basis of the coupling between the template and the model. The template defines a representation of the object which is simpler to interpret than the model. Because the template of the invention is coupled to the model, the position, orientation and/or shape of the template is determined by the model adapted to the object in the image data. Hence, the template is adapted to the image data. The adapted template is capable of representing the object and its individual characteristics.

9. 发明授权

US09171377B2 Automatic point-wise validation of respiratory motion estimation 有权
标题翻译：自动点对点呼吸运动估计
公开(公告)号：US09171377B2
公开(公告)日：2015-10-27
申请号：US13808607
申请日：2011-07-05
申请人： Sven Kabus , Tobias Klinder , Cristian Lorenz
发明人： Sven Kabus , Tobias Klinder , Cristian Lorenz
IPC分类号： G06K9/00 , G06T7/20 , G06T3/00 , G06T7/00
CPC分类号： G06T7/20 , G06T3/0081 , G06T7/0016 , G06T7/30 , G06T2207/10081 , G06T2207/30061
摘要： A system for validating motion estimation comprising a field unit (110) for obtaining a deformation vector field (DVF) estimating the motion by transforming a first image at a first phase of the motion into a second image at a second phase of the motion, a metric unit (120) for computing a metric of a local volume change at a plurality of locations, and a conformity unit (130) for computing a conformity measure based on the computed metric of the local volume change at the plurality of locations and a local property of the first or second image defined at the plurality of locations. Based on the value of the conformity measure, the DFV estimating the motion is validated. Experiments show that the conformity measure based on the computed metric of a local volume change at a plurality of locations and the local property of the first or second image, defined at the plurality of locations, does not necessarily favor a large weight for the outer force to provide a more accurate registration. One reason for this observation may be that large deformations providing more accurate alignment often lead to deformations resulting in unreasonably large volume changes. DVFs comprising such deformations thus are more likely to be discarded by the system of the invention.
摘要翻译：一种用于验证运动估计的系统，包括：场单元（110），用于通过在运动的第二阶段将运动的第一阶段的第一图像变换为第二图像来获得估计运动的变形矢量场（DVF）; 用于计算多个位置处的本地卷变化的度量的度量单位（120），以及用于基于所计算的所述多个位置处的本地卷变化的度量的度量单位（130）以及局部在多个位置定义的第一或第二图像的属性。根据合格度的值，对运动的DFV进行了验证。实验表明，基于多个位置处的局部体积变化的计算度量和在多个位置处限定的第一或第二图像的局部属性的一致性度量不一定有利于外力的大重量提供更准确的注册。这种观察的一个原因可能是提供更精确对准的大变形通常导致变形，导致不合理地大的体积变化。包括这种变形的DVF因此更可能被本发明的系统丢弃。

10. 发明申请

US20130108117A1 AUTOMATIC POINT-WISE VALIDATION OF RESPIRATORY MOTION ESTIMATION 有权
标题翻译：呼吸运动估计的自动点智慧验证
公开(公告)号：US20130108117A1
公开(公告)日：2013-05-02
申请号：US13808607
申请日：2011-07-05
申请人： Sven Kabus , Tobias Klinder , Cristian Lorenz
发明人： Sven Kabus , Tobias Klinder , Cristian Lorenz
IPC分类号： G06T7/20
CPC分类号： G06T7/20 , G06T3/0081 , G06T7/0016 , G06T7/30 , G06T2207/10081 , G06T2207/30061
摘要： A system for validating motion estimation comprising a field unit (110) for obtaining a deformation vector field (DVF) estimating the motion by transforming a first image at a first phase of the motion into a second image at a second phase of the motion, a metric unit (120) for computing a metric of a local volume change at a plurality of locations, and a conformity unit (130) for computing a conformity measure based on the computed metric of the local volume change at the plurality of locations and a local property of the first or second image defined at the plurality of locations. Based on the value of the conformity measure, the DFV estimating the motion is validated. Experiments show that the conformity measure based on the computed metric of a local volume change at a plurality of locations and the local property of the first or second image, defined at the plurality of locations, does not necessarily favor a large weight for the outer force to provide a more accurate registration. One reason for this observation may be that large deformations providing more accurate alignment often lead to deformations resulting in unreasonably large volume changes. DVFs comprising such deformations thus are more likely to be discarded by the system of the invention.
摘要翻译：一种用于验证运动估计的系统，包括：场单元（110），用于通过在运动的第二阶段将运动的第一阶段的第一图像变换为第二图像来获得估计运动的变形矢量场（DVF）; 用于计算多个位置处的本地卷变化的度量的度量单位（120），以及用于基于所计算的所述多个位置处的本地卷变化的度量的度量单位（130）以及局部在多个位置定义的第一或第二图像的属性。根据合格度的值，对运动的DFV进行了验证。实验表明，基于多个位置处的局部体积变化的计算度量和在多个位置处限定的第一或第二图像的局部属性的一致性度量不一定有利于外力的大重量提供更准确的注册。这种观察的一个原因可能是提供更精确对准的大变形通常导致变形，导致不合理地大的体积变化。包括这种变形的DVF因此更可能被本发明的系统丢弃。

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