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1. 发明申请

US20080312726A1 Implantable Hermetically Sealed Structures 有权
标题翻译：植入式密封结构
公开(公告)号：US20080312726A1
公开(公告)日：2008-12-18
申请号：US11794016
申请日：2005-12-22
申请人： Jeremy Frank , Vladimir Gelfandbein , Marc Jensen , Mark Zdeblick , Benedict J. Costello
发明人： Jeremy Frank , Vladimir Gelfandbein , Marc Jensen , Mark Zdeblick , Benedict J. Costello
IPC分类号： A61N1/05
CPC分类号： A61N1/375 , A61N1/05 , A61N1/37205 , A61N1/3756
摘要： Implantable hermetically sealed structures and methods for making the same are provided. Also provided are devices, systems and kits including the hermetically sealed structures, as well as methods of using such devices and systems.
摘要翻译：提供了可植入密封结构及其制造方法。还提供了包括密封结构的装置，系统和试剂盒以及使用这种装置和系统的方法。

2. 发明申请

US20080255647A1 Implantable Addressable Segmented Electrodes 审中-公开
标题翻译：可植入可寻址分段电极
公开(公告)号：US20080255647A1
公开(公告)日：2008-10-16
申请号：US11793904
申请日：2005-12-22
申请人： Marc Jensen , Benedict J. Costello , Todd Thompson , Mark Zdeblick , Jeremy Frank , Dino Lei , Olivier Colliou , George M. Savage
发明人： Marc Jensen , Benedict J. Costello , Todd Thompson , Mark Zdeblick , Jeremy Frank , Dino Lei , Olivier Colliou , George M. Savage
IPC分类号： A61N1/05
CPC分类号： A61N1/05 , A61N1/375
摘要： Implantable addressable segmented electrode devices, as well as methods for making and using the same, are provided. The subject devices include segmented electrode structures made up of an integrated circuit electrically coupled to two or more electrodes, where each electrode can be individually activated. Also provided are implantable devices and systems, as well as kits containing such devices and systems or components thereof, which include the segmented electrode structures.
摘要翻译：提供了可植入可寻址的分段电极装置，以及制造和使用它们的方法。主题装置包括由电耦合到两个或更多个电极的集成电路构成的分段电极结构，其中每个电极可以被单独激活。还提供了可植入装置和系统，以及包含这种装置和系统或其组件的试剂盒，其包括分段的电极结构。

3. 发明申请

US20120011699A1 HIGH-THROUGHPUT PRODUCTION OF INGESTIBLE EVENT MARKERS 审中-公开
标题翻译：高效率生产不可思议的事件标记
公开(公告)号：US20120011699A1
公开(公告)日：2012-01-19
申请号：US12741583
申请日：2010-01-05
申请人： Hooman Hafezi , Mark Zdeblick , Kityee Au-Yeung , Gregory Moon , Robert Duck , Maria Casillas Holen , Timothy Robertson , Eric Snyder , Mauro Folena , Benedict J. Costello , Pratish Rao
发明人： Hooman Hafezi , Mark Zdeblick , Kityee Au-Yeung , Gregory Moon , Robert Duck , Maria Casillas Holen , Timothy Robertson , Eric Snyder , Mauro Folena , Benedict J. Costello , Pratish Rao
IPC分类号： B23P25/00 , B23P21/00
CPC分类号： A61B5/073 , A61B5/0031 , A61B5/4238 , A61B5/4255 , A61B2560/0406 , A61B2562/12 , A61B2562/162 , B01L3/545 , B30B11/34 , Y10T29/49885 , Y10T29/5191
摘要： High-throughput ingestible event marker manufacturing systems are provided. The systems include an assembly unit configured to stably associate an ingestible event marker with a carrier to produce a product. Also provided are manufacturing methods to produce such products which include assembling an ingestible event marker with an assembly unit configured to stably associate an ingestible event marker with a carrier.
摘要翻译：提供高通量可摄入事件标记制造系统。系统包括组装单元，其被配置为稳定地将可摄入事件标记与载体相关联以产生产物。还提供了制造这样的产品的制造方法，其包括将可摄取事件标记与组装单元组合，其被配置为将可摄取事件标记与载体稳定相关联。

4. 发明申请

US20110022113A1 Analyzer Compatible Communication Protocol 审中-公开
标题翻译：分析仪兼容通讯协议
公开(公告)号：US20110022113A1
公开(公告)日：2011-01-27
申请号：US12669031
申请日：2009-11-30
申请人： Mark Zdeblick , Lawrence Arne , Nilay Jani , Haifeng Li , Jonathan Withrington , Benedict J. Costello , Alexander Gilman , Adam Whitworth
发明人： Mark Zdeblick , Lawrence Arne , Nilay Jani , Haifeng Li , Jonathan Withrington , Benedict J. Costello , Alexander Gilman , Adam Whitworth
IPC分类号： A61N1/08
CPC分类号： A61N1/368 , A61B5/0031 , A61B5/0402 , A61B5/4519 , A61N1/025 , A61N1/36185 , A61N1/3684 , A61N1/3686 , A61N1/37241 , A61N1/37252
摘要： Methods and systems for programming a plurality of leads under at least two distinct modalities are provided. The leads may be grouped within satellites and multiple satellites may be configured within a single lead. Each lead includes a power and communications bus providing commands, and information and pulses to the satellites. The leads may be connected to at least two different command and pulse sources, optionally a cardiac pacemaker and/or a cardiac pulse analyzer system. A command may include or be preceded by a wake-up pulse that facilitates identification of a modality applicable to the associated command and data. A command may further optionally include a reference pulse or series of reference pulses, whereby the satellite references data pulses in relation to one or more aspects of the associated reference pulse. A data pulse may deliver two bits of information.
摘要翻译：提供了用于在至少两个不同模态下编程多个引线的方法和系统。引线可以分组在卫星内，并且可以在单个引线内配置多个卫星。每个引线包括一个电源和通信总线，它们向卫星提供命令，以及信息和脉冲。引线可以连接到至少两个不同的命令和脉冲源，可选地连接到心脏起搏器和/或心脏脉搏分析器系统。命令可以包括唤醒脉冲之前或之前，唤醒脉冲便于识别适用于相关命令和数据的模态。命令还可以可选地包括参考脉冲或一系列参考脉冲，由此卫星相对于相关参考脉冲的一个或多个方面引用数据脉冲。数据脉冲可以传送两位信息。

5. 发明授权

US06628856B1 Optical switch 有权
标题翻译：光开关
公开(公告)号：US06628856B1
公开(公告)日：2003-09-30
申请号：US09671377
申请日：2000-09-27
申请人： Benedict J. Costello , Peter T. Jones , Ho-Shang Lee
发明人： Benedict J. Costello , Peter T. Jones , Ho-Shang Lee
IPC分类号： G02B626
CPC分类号： G02B6/3518 , G02B6/3556 , G02B6/357 , G02B6/3582
摘要： The optical switch includes input optical fibers, output optical fibers, a lens, a movable mirror, and an actuator operative to move the mirror. Depending on a voltage applied to the actuator, the actuator selectively set the mirror to a first position corresponding to a first combination of optical paths, through which the light beam travels from the first set of the input optical fibers to the second set of the output optical fibers; and to a second position corresponding to a second combination of optical paths, through which the light beam travels from the first set to the second set. The first combination is different from the second combination, and a number of optical fibers of the first set and the second set is more than two.
摘要翻译：光开关包括输入光纤，输出光纤，透镜，可移动反射镜和可操作以移动反射镜的致动器。根据施加到致动器的电压，致动器选择性地将镜子设置为对应于光路的第一组合的第一位置，光束从第一组输入光纤传播到第二组输出光纤; 以及对应于光路的第二组合的第二位置，光束通过该光路从第一组传播到第二组。第一组合与第二组合不同，并且第一组和第二组的多个光纤多于两个。

6. 发明授权

US5212988A Plate-mode ultrasonic structure including a gel 失效
标题翻译：板状超声波结构包括凝胶
公开(公告)号：US5212988A
公开(公告)日：1993-05-25
申请号：US775631
申请日：1991-10-10
申请人： Richard M. White , Stuart W. Wenzel , Benedict J. Costello
发明人： Richard M. White , Stuart W. Wenzel , Benedict J. Costello
IPC分类号： B01L3/00 , G01H13/00 , G01H17/00 , G01L9/00 , G01N29/02 , G01P15/08 , G10K11/36 , H03H9/42
CPC分类号： G01N29/2437 , B01L3/5027 , G01H13/00 , G01H17/00 , G01L9/0025 , G01N29/022 , G01P15/08 , G10K11/36 , H03H9/42 , B01L2300/0663 , B01L2300/1827 , B01L2400/0421 , G01N2291/014 , G01N2291/0255 , G01N2291/0256 , G01N2291/02818 , G01N2291/02827 , G01N2291/02854 , G01N2291/0427
摘要： An ultrasonic structure which has a thin planar sheet of material forming a Lamb wave propagation medium The propagation medium is coated with a gel. The structure may also include a Lamb wave generator for generating Lamb waves in the propagation medium and an output device for producing an electrical signal representative of the propagation characteristics of the Lamb waves propagating along the propagation medium. A measuring device can be included to measure selected characteristics of the output electrical signal. The propagation medium has some physical characteristics that are determined by the value of a measurand acting on the medium and the determined physical characteristics determine the propagation characteristics of the Lamb waves which are propagated along the medium. When the sensor is acted on by a measurand to determine the physical characteristics of the propagation medium, the characteristics of the electrical signal are also determined. The measuring device measures the electrical signal and provides an indication of the measurand value.
摘要翻译：具有形成兰姆波传播介质的薄平板材料的超声波结构传播介质用凝胶涂覆。该结构还可以包括用于在传播介质中产生兰姆波的兰姆波发生器和用于产生表示沿着传播介质传播的兰姆波传播特性的电信号的输出装置。可以包括测量装置来测量输出电信号的选定特性。传播介质具有由作用在介质上的被测量的值确定的一些物理特性，并且所确定的物理特性确定沿着介质传播的兰姆波的传播特性。当传感器被被测量作用以确定传播介质的物理特性时，也确定电信号的特性。测量设备测量电信号并提供被测量值的指示。

7. 发明申请

US20080183072A1 Continuous field tomography 审中-公开
标题翻译：连续场断层扫描
公开(公告)号：US20080183072A1
公开(公告)日：2008-07-31
申请号：US11664340
申请日：2007-03-30
申请人： Timothy L. Robertson , George M. Savage , Todd Thompson , Mark J. Zdeblick , Olivier Colliou , Benedict J. Costello
发明人： Timothy L. Robertson , George M. Savage , Todd Thompson , Mark J. Zdeblick , Olivier Colliou , Benedict J. Costello
IPC分类号： A61B5/05
CPC分类号： A61B5/1107 , A61B5/0031 , A61B5/686 , A61B8/12 , A61B8/488 , A61B8/56 , A61B2562/046 , A61N1/3627 , A61N1/365
摘要： Methods for evaluating motion of a tissue, such as of a cardiac location, e.g., heart wall, via continuous field tomography are provided. In the subject methods, a continuous field (e.g., an electrical, mechanical, electro-mechanical, or other field) sensing element is stably associated with the tissue location. A property of the applied continuous field is detected with the sensing element to evaluate movement of the tissue location. Also provided are systems, devices and related compositions for practicing the subject methods. The subject methods and devices find use in a variety of different applications, including cardiac resynchronization therapy.
摘要翻译：提供了通过连续场断层摄影评估诸如心脏位置（例如心脏壁）的组织运动的方法。在主题方法中，连续场（例如，电，机械，机电或其他场）感测元件与组织位置稳定地相关联。使用感测元件检测所施加的连续场的属性，以评估组织位置的运动。还提供了用于实践主题方法的系统，装置和相关组合物。主题方法和设备可用于各种不同的应用，包括心脏再同步治疗。

8. 发明申请

US20080242976A1 Electric field tomography 审中-公开
标题翻译：电场断层扫描
公开(公告)号：US20080242976A1
公开(公告)日：2008-10-02
申请号：US11664468
申请日：2007-03-30
申请人： Timothy L. Robertson , Olivier Colliou , Benedict J. Costello , George M. Savage , Todd Thompson , Mark J. Zdeblick
发明人： Timothy L. Robertson , Olivier Colliou , Benedict J. Costello , George M. Savage , Todd Thompson , Mark J. Zdeblick
IPC分类号： A61B5/04
CPC分类号： A61B5/1107 , A61B5/686 , A61B2562/046 , A61N1/056 , A61N1/3627 , A61N1/36514 , A61N1/36578 , A61N1/368 , A61N1/3684 , A61N1/375 , A61N1/3752 , A61N1/3756 , A61N2001/0585
摘要： Methods for evaluating motion of a tissue, such as of a cardiac location, e.g., heart wall, via continuous field tomography are provided. In the subject methods, a continuous field (e.g., an electrical, mechanical, electromechanical, or other field) sensing element is stably associated with the tissue location. A property of the applied continuous field is detected with the sensing element to evaluate movement of the tissue location. Also provided are systems, devices and related compositions for practicing the subject methods. The subject methods and devices find use in a variety of different applications, including cardiac resynchronization therapy.
摘要翻译：提供了通过连续场断层摄影评估诸如心脏位置（例如心脏壁）的组织运动的方法。在主题方法中，连续场（例如，电，机械，机电或其他场）感测元件与组织位置稳定地相关联。使用感测元件检测所施加的连续场的属性，以评估组织位置的运动。还提供了用于实践主题方法的系统，装置和相关组合物。主题方法和设备可用于各种不同的应用，包括心脏再同步治疗。

9. 发明授权

US06720710B1 Micropump 失效
标题翻译：微型泵
公开(公告)号：US06720710B1
公开(公告)日：2004-04-13
申请号：US08779545
申请日：1997-01-06
申请人： Stuart W. Wenzel , Benedict J. Costello
发明人： Stuart W. Wenzel , Benedict J. Costello
IPC分类号： H01L4108
CPC分类号： G01N30/6095 , B01J2219/00891 , B01J2219/00916 , B01J2219/00932 , B01J2219/00952 , B01L3/50273 , B01L5/02 , B01L2200/10 , B01L2300/0816 , B01L2300/087 , B01L2300/088 , B01L2300/0883 , B01L2400/0439 , B01L2400/0496 , B82Y30/00 , F04B17/00 , F04B43/043 , F04B43/046 , G01N30/32 , G01N30/44 , G01N2030/122 , G01N2030/123 , G01N2030/326 , G01N2030/623 , G01N2030/77 , B01D2015/389 , G01N2030/285
摘要： A microsized pump is set forth. It comprises a substrate which at least partially defines one or more walls of a longitudinally extending tunnel. The tunnel has a vibratable wall portion. A sonic energy generator is positioned in sonic energy transmitting relation to the vibratable wall portion. The sonic energy generator is adapted to generate elastic waves which travel along the longitudinal extension of the tunnel. The pump is useful for moving material along the tunnel whereby chemical and biological analysis and reactions can be carried out on a micro scale.
摘要翻译：阐述了微型泵。其包括至少部分地限定纵向延伸的隧道的一个或多个壁的基底。隧道具有可振动的壁部分。声能量发生器位于与可振动壁部分的声能传递关系中。声能量发生器适于产生沿着隧道的纵向延伸行进的弹性波。泵可用于沿着隧道移动材料，从而可以在微观尺度上进行化学和生物学分析和反应。

10. 发明授权

US06838738B1 Electrostatic control of micro-optical components 有权
标题翻译：微光元件的静电控制
公开(公告)号：US06838738B1
公开(公告)日：2005-01-04
申请号：US10081496
申请日：2002-02-20
申请人： Benedict J. Costello , Peter T. Jones , Ho-Shang Lee
发明人： Benedict J. Costello , Peter T. Jones , Ho-Shang Lee
IPC分类号： G02B6/26 , G02B6/35 , H02N1/00 , H01L27/14 , H01L29/82 , H01L29/84
CPC分类号： G02B6/357 , G01J3/26 , G02B6/266 , G02B6/3518 , G02B6/3548 , G02B6/3582 , G02B6/3584 , G02B6/3594 , H02N1/008
摘要： An electrostatic actuator with inter-digital rotor and stator fingers formed in a the insulating and conductive layers of a wafer. The actuator is used to drive MicroElectroMechanical (MEMS) components, specifically micro-optical components such as mirrors, attenuators, switches, and tunable filters.
摘要翻译：具有数字转子和定子指状物的静电致动器，其形成在晶片的绝缘和导电层中。致动器用于驱动MicroElectroMechanical（MEMS）组件，特别是微光学组件，如镜子，衰减器，开关和可调谐滤波器。

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