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1. 发明申请

US20080183072A1 Continuous field tomography 审中-公开
标题翻译：连续场断层扫描
公开(公告)号：US20080183072A1
公开(公告)日：2008-07-31
申请号：US11664340
申请日：2007-03-30
申请人： Timothy L. Robertson , George M. Savage , Todd Thompson , Mark J. Zdeblick , Olivier Colliou , Benedict J. Costello
发明人： Timothy L. Robertson , George M. Savage , Todd Thompson , Mark J. Zdeblick , Olivier Colliou , Benedict J. Costello
IPC分类号： A61B5/05
CPC分类号： A61B5/1107 , A61B5/0031 , A61B5/686 , A61B8/12 , A61B8/488 , A61B8/56 , A61B2562/046 , A61N1/3627 , A61N1/365
摘要： Methods for evaluating motion of a tissue, such as of a cardiac location, e.g., heart wall, via continuous field tomography are provided. In the subject methods, a continuous field (e.g., an electrical, mechanical, electro-mechanical, or other field) sensing element is stably associated with the tissue location. A property of the applied continuous field is detected with the sensing element to evaluate movement of the tissue location. Also provided are systems, devices and related compositions for practicing the subject methods. The subject methods and devices find use in a variety of different applications, including cardiac resynchronization therapy.
摘要翻译：提供了通过连续场断层摄影评估诸如心脏位置（例如心脏壁）的组织运动的方法。在主题方法中，连续场（例如，电，机械，机电或其他场）感测元件与组织位置稳定地相关联。使用感测元件检测所施加的连续场的属性，以评估组织位置的运动。还提供了用于实践主题方法的系统，装置和相关组合物。主题方法和设备可用于各种不同的应用，包括心脏再同步治疗。

2. 发明申请

US20080242976A1 Electric field tomography 审中-公开
标题翻译：电场断层扫描
公开(公告)号：US20080242976A1
公开(公告)日：2008-10-02
申请号：US11664468
申请日：2007-03-30
申请人： Timothy L. Robertson , Olivier Colliou , Benedict J. Costello , George M. Savage , Todd Thompson , Mark J. Zdeblick
发明人： Timothy L. Robertson , Olivier Colliou , Benedict J. Costello , George M. Savage , Todd Thompson , Mark J. Zdeblick
IPC分类号： A61B5/04
CPC分类号： A61B5/1107 , A61B5/686 , A61B2562/046 , A61N1/056 , A61N1/3627 , A61N1/36514 , A61N1/36578 , A61N1/368 , A61N1/3684 , A61N1/375 , A61N1/3752 , A61N1/3756 , A61N2001/0585
摘要： Methods for evaluating motion of a tissue, such as of a cardiac location, e.g., heart wall, via continuous field tomography are provided. In the subject methods, a continuous field (e.g., an electrical, mechanical, electromechanical, or other field) sensing element is stably associated with the tissue location. A property of the applied continuous field is detected with the sensing element to evaluate movement of the tissue location. Also provided are systems, devices and related compositions for practicing the subject methods. The subject methods and devices find use in a variety of different applications, including cardiac resynchronization therapy.
摘要翻译：提供了通过连续场断层摄影评估诸如心脏位置（例如心脏壁）的组织运动的方法。在主题方法中，连续场（例如，电，机械，机电或其他场）感测元件与组织位置稳定地相关联。使用感测元件检测所施加的连续场的属性，以评估组织位置的运动。还提供了用于实践主题方法的系统，装置和相关组合物。主题方法和设备可用于各种不同的应用，包括心脏再同步治疗。

3. 发明授权

US08540632B2 Low profile antenna for in body device 有权
标题翻译：用于体内器件的低调天线
公开(公告)号：US08540632B2
公开(公告)日：2013-09-24
申请号：US12126792
申请日：2008-05-23
申请人： Timothy L. Robertson , Olivier Colliou , Eric Snyder , Mark J. Zdeblick
发明人： Timothy L. Robertson , Olivier Colliou , Eric Snyder , Mark J. Zdeblick
IPC分类号： A61B5/07
CPC分类号： A61B5/07 , A61B1/00016 , A61B1/041 , H01Q1/2208 , H01Q1/36
摘要： Low profile antennas for ingestible devices, such as ingestible event markers, are provided. Aspects of the ingestible devices of the invention include low profile signal transmission antennas configured such that they are flexible or degrade after use, allowing the antenna and attached components to pass easily through the body. Embodiments of the low profile antennas are configured to emit a detectable signal upon contact with a target physiological site. Also provided are methods of making and using the devices of the invention.
摘要翻译：提供用于可摄取装置的低轮廓天线，例如可摄取事件标记。本发明的可摄取装置的方面包括配置成在使用后它们是柔性的或降级的低轮廓信号传输天线，允许天线和附接的部件容易地穿过身体。低轮廓天线的实施例被配置为在与目标生理部位接触时发出可检测信号。还提供了制造和使用本发明的装置的方法。

4. 发明申请

US20130002423A1 RFID Antenna for In-Body Device 审中-公开
标题翻译：用于体内装置的RFID天线
公开(公告)号：US20130002423A1
公开(公告)日：2013-01-03
申请号：US13345518
申请日：2012-01-06
申请人： Timothy L. Robertson , Olivier Colliou , Eric J. Snyder , Mark J. Zdeblick
发明人： Timothy L. Robertson , Olivier Colliou , Eric J. Snyder , Mark J. Zdeblick
IPC分类号： G06K7/01
CPC分类号： A61B5/07 , A61B1/00016 , A61B1/041 , H01Q1/2208 , H01Q1/36
摘要： RFID antennas for ingestible devices, such as ingestible event markers, are provided. Aspects of the ingestible devices of the invention include RFID signal transmission antennas with a battery that is activated upon being exposed to fluid in the body. Embodiments of the RFID antennas are configured to emit a detectable signal upon contact with a target physiological site. Also provided are methods of making and using the devices of the invention.
摘要翻译：提供了可摄取装置的RFID天线，例如可摄取事件标记。本发明的可摄取装置的方面包括具有电池的RFID信号传输天线，其在暴露于身体中的流体时被激活。 RFID天线的实施例被配置为在与目标生理部位接触时发出可检测信号。还提供了制造和使用本发明的装置的方法。

5. 发明授权

US08115618B2 RFID antenna for in-body device 有权
标题翻译：用于体内装置的RFID天线
公开(公告)号：US08115618B2
公开(公告)日：2012-02-14
申请号：US12126798
申请日：2008-05-23
申请人： Timothy L. Robertson , Olivier Colliou , Eric J. Snyder , Mark J. Zdeblick
发明人： Timothy L. Robertson , Olivier Colliou , Eric J. Snyder , Mark J. Zdeblick
IPC分类号： G08B1/08
CPC分类号： A61B5/07 , A61B1/00016 , A61B1/041 , H01Q1/2208 , H01Q1/36
摘要： RFID antennas for ingestible devices, such as ingestible event markers, are provided. Aspects of the ingestible devices of the invention include RFID signal transmission antennas with a battery that is activated upon being exposed to fluid in the body. Embodiments of the RFID antennas are configured to emit a detectable signal upon contact with a target physiological site. Also provided are methods of making and using the devices of the invention.
摘要翻译：提供了可摄取装置的RFID天线，例如可摄取事件标记。本发明的可摄取装置的方面包括具有电池的RFID信号传输天线，其在暴露于身体中的流体时被激活。 RFID天线的实施例被配置为在与目标生理部位接触时发出可检测信号。还提供了制造和使用本发明的装置的方法。

6. 发明申请

US20080306360A1 LOW PROFILE ANTENNA FOR IN BODY DEVICE 有权
标题翻译：用于身体装置的低剖面天线
公开(公告)号：US20080306360A1
公开(公告)日：2008-12-11
申请号：US12126792
申请日：2008-05-23
申请人： Timothy L. Robertson , Olivier Colliou , Eric J. Snyder , Mark J. Zdeblick
发明人： Timothy L. Robertson , Olivier Colliou , Eric J. Snyder , Mark J. Zdeblick
IPC分类号： A61B5/07 , H01Q1/36
CPC分类号： A61B5/07 , A61B1/00016 , A61B1/041 , H01Q1/2208 , H01Q1/36
摘要： Low profile antennas for ingestible devices, such as ingestible event markers, are provided. Aspects of the ingestible devices of the invention include low profile signal transmission antennas configured such that they are flexible or degrade after use, allowing the antenna and attached components to pass easily through the body. Embodiments of the low profile antennas are configured to emit a detectable signal upon contact with a target physiological site. Also provided are methods of making and using the devices of the invention.
摘要翻译：提供用于可摄取装置的低轮廓天线，例如可摄取事件标记。本发明的可摄取装置的方面包括配置成在使用后它们是柔性的或降级的低轮廓信号传输天线，允许天线和附接的部件容易地穿过身体。低轮廓天线的实施例被配置为在与目标生理部位接触时发出可检测信号。还提供了制造和使用本发明的装置的方法。

7. 发明授权

US08961412B2 In-body device with virtual dipole signal amplification 有权
标题翻译：具有虚拟偶极子信号放大的体内器件
公开(公告)号：US08961412B2
公开(公告)日：2015-02-24
申请号：US12238345
申请日：2008-09-25
申请人： Hooman Hafezi , Benedict James Costello , Timothy L. Robertson , Maria Casillas Holen
发明人： Hooman Hafezi , Benedict James Costello , Timothy L. Robertson , Maria Casillas Holen
IPC分类号： A61B5/07 , A61B5/00 , H04B13/00 , A61B5/145 , H01Q1/22 , H01Q1/27 , H01Q9/16 , H01B1/00 , H04B3/00 , H01Q1/00
CPC分类号： A61B5/073 , A61B5/0002 , A61B5/0028 , A61B5/028 , A61B5/14539 , A61B5/14546 , A61B2562/02 , A61B2562/162 , A61B2562/182 , H01Q1/2208 , H01Q1/273 , H01Q9/16 , H04B13/005 , Y10S128/902
摘要： Virtual dipole signal amplification for in-body devices, such as implantable and ingestible devices, is provided. Aspects of the in-body deployable antennas of the invention include antennas configured to go from a first configuration to a second configuration following placement in a living body, e.g., via ingestion or implantation. Embodiments of the in-body devices are configured to emit a detectable signal upon contact with a target physiological site. Also provided are methods of making and using the devices of the invention.
摘要翻译：提供了诸如可植入和可摄取装置的体内装置的虚拟偶极子信号放大。本发明的体内可展开天线的方面包括配置成在放置在生物体中（例如通过摄取或植入）之后从第一配置转变为第二配置的天线。身体内装置的实施例被配置为在与目标生理部位接触时发出可检测信号。还提供了制造和使用本发明的装置的方法。

8. 发明授权

US06798800B2 Method and apparatus to sense temperature of thermal tuning elements in tunable optical devices 有权
公开(公告)号：US06798800B2
公开(公告)日：2004-09-28
申请号：US10334509
申请日：2002-12-30
申请人： Douglas A. Sprock , Robert A. Carney , Timothy L. Robertson
发明人： Douglas A. Sprock , Robert A. Carney , Timothy L. Robertson
IPC分类号： H01S304
CPC分类号： G01K7/206 , G01K7/20
摘要： A tunable optical unit includes a resistive temperature device (RTD), a thermal tuning device and a measurement circuit. The RTD has a resistance dependent on a temperature of the thermal tuning device. The measurement circuit outputs a signal that is dependent on the resistance of the RTD. The signal is used to control the temperature of the thermal tuning device in tuning the tunable optical unit. A reference resistance can be connected in series with the RTD to make ratio-metric measurements to determine the RTD's resistance (and hence the temperature of the tuning elements) without having to know the value of the current conducted through the RTD and to reduce sensitivity to fluctuations in the excitation signal.

9. 发明授权

US08172762B2 Simultaneous blood flow and hematocrit sensor 有权
标题翻译：同时血流量和血细胞比容传感器
公开(公告)号：US08172762B2
公开(公告)日：2012-05-08
申请号：US11897942
申请日：2007-08-31
申请人： Timothy L. Robertson
发明人： Timothy L. Robertson
IPC分类号： A61B5/02
CPC分类号： A61B5/026 , A61B5/0031 , A61B5/14535 , G06F19/00
摘要： Embodiments of the present invention provide blood flow sensors that can be used for measurement of various physiological parameters under a wide array of conditions. In some embodiments, the blood flow sensor can be implanted into a blood vessel and left in place indefinitely and will unobtrusively measure and record data as the patient engages in regular daily activities. The data can later be read out by a clinician using a suitable interface. In other embodiments, the data is collected and analyzed within a data collection device implanted in or attached to the patient's body, and the collection device can report to the patient on an ongoing basis or in the form of alerts issued when conditions requiring medical intervention are detected.
摘要翻译：本发明的实施例提供可用于在广泛条件下测量各种生理参数的血液流量传感器。在一些实施例中，血液流量传感器可以被植入血管并且无限期地保持在适当的位置，并且将随着患者进行常规的日常活动而不经意地地测量和记录数据。数据随后可以由临床医生使用合适的界面读出。在其他实施例中，在植入或附接到患者身体的数据收集装置内收集和分析数据，并且收集装置可以持续基础或以需要医疗干预的条件发出的警报的形式向患者报告检测到。

10. 发明申请

US20110150014A1 ANALOG TEMPERATURE CONTROL FOR TUNABLE LASERS 审中-公开
标题翻译：模拟温度控制用于激光激光
公开(公告)号：US20110150014A1
公开(公告)日：2011-06-23
申请号：US12540946
申请日：2009-08-13
申请人： Andrew Daiber , Mark Stephen Rice , Timothy L. Robertson
发明人： Andrew Daiber , Mark Stephen Rice , Timothy L. Robertson
IPC分类号： H01S3/10 , H01S3/00
CPC分类号： H01S5/06804
摘要： An analog circuit including a voltage divider for providing a first voltage corresponding to an actual temperature of said thermal tuning element of the laser; an analog comparator generating an analog output current for comparing the first voltage with a reference voltage, the reference voltage being representative of a temperature of said thermal tuning element of the laser corresponding to a desired wavelength of the laser; and a heating element thermally coupled to said thermal tuning element, wherein the analog comparator increases said analog current to the heating element, when the first voltage is less than the reference voltage; and decreases said analog current to the heating element, when the first voltage is larger than the second reference voltage.
摘要翻译：一种包括分压器的模拟电路，用于提供对应于所述激光器的所述热调谐元件的实际温度的第一电压; 模拟比较器产生用于将第一电压与参考电压进行比较的模拟输出电流，所述参考电压代表对应于所述激光器的期望波长的所述激光器的所述热调谐元件的温度; 以及加热元件，其热耦合到所述热调谐元件，其中当所述第一电压小于所述参考电压时，所述模拟比较器将所述模拟电流增加到所述加热元件; 并且当所述第一电压大于所述第二参考电压时，将所述模拟电流减小到所述加热元件。

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