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1. 发明申请

US20120003626A1 SAMPLING DEVICES AND METHODS FOR CONCENTRATING MICROORGANISMS 有权
标题翻译：采样装置和浓缩微生物的方法
公开(公告)号：US20120003626A1
公开(公告)日：2012-01-05
申请号：US13142288
申请日：2009-12-30
申请人： Manjiri T. Kshirsagar , Kurt J. Halverson , Neil Percy , James E. Aysta
发明人： Manjiri T. Kshirsagar , Kurt J. Halverson , Neil Percy , James E. Aysta
IPC分类号： C12Q1/04 , C12N1/20 , C12N1/14 , C12N1/10 , C12M1/26 , C12M1/34 , C12Q1/70 , C12N7/02 , C12N1/16 , B82Y15/00
CPC分类号： C12Q1/24 , C12M47/02 , C12M47/04 , G01N1/40 , G01N1/405 , G01N2001/4088
摘要： The present disclosure describes methods for concentrating microorganisms with concentration agents in a sampling device and the sampling device described herein. More specifically, methods for concentrating microorganisms from large volume samples with concentration agents in a sampling device can provide for rapid, low cost, simple (involving no complex equipment or procedures), and/or effective processes under a variety of conditions.
摘要翻译：本公开描述了将浓缩剂浓缩在采样装置中的微生物和本文所述的采样装置的方法。更具体地说，用于将来自大容量样品的微生物浓缩在采样装置中的浓缩剂的方法可以在各种条件下提供快速，低成本，简单（不涉及复杂的设备或程序）和/或有效过程。

2. 发明授权

US5464541A Device and a method for separating liquid samples 失效
标题翻译：装置和分离液体样品的方法
公开(公告)号：US5464541A
公开(公告)日：1995-11-07
申请号：US153463
申请日：1993-11-17
申请人： James E. Aysta , Metin Colpan
发明人： James E. Aysta , Metin Colpan
IPC分类号： B01D15/00 , B01D24/00 , B01D29/01 , B01D61/18 , B01L3/00 , B01L99/00 , C12M1/00 , C12Q1/68 , B01D29/00
CPC分类号： B01L3/5025 , B01D61/18 , B01L3/50255 , B01L3/50855 , Y10T436/25375 , Y10T436/255
摘要： A device (10) for separating liquid samples has a sample container (12), bottom wall (20) of which has an outlet opening (22) provided therein. The outlet opening (22) is joined by an outlet spout (24) extending in the axial direction of the sample container (12). On bottom wall (20) there is a separation layer (28). Below sample container (12), a collecting container (32) is arranged abutting sample container (12) such that an exchange of air between the interior of the collecting chamber (32) and the environment is possible, yet an escape of liquid is largely inhibited. The contact surface between collecting chamber (32) and sample container (12) and end (26) of the outlet spout (24) through which the liquid is discharged, are axially spaced apart.
摘要翻译：用于分离液体样品的装置（10）具有样品容器（12），其底壁（20）具有设置在其中的出口（22）。出口开口（22）通过在样品容器（12）的轴向方向上延伸的出口喷口（24）连接。在底壁（20）上有分离层（28）。在样本容器（12）的下面，收集容器（32）设置成邻接样本容器（12），使得可以在收集室（32）的内部和环境之间交换空气，但是液体逸出很大程度上抑制。收集室（32）和样品容器（12）之间的接触表面以及排出液体的出口喷口（24）的端部（26）轴向间隔开。

3. 发明授权

US5283039A Multi-well filtration apparatus 失效
标题翻译：多孔过滤装置
公开(公告)号：US5283039A
公开(公告)日：1994-02-01
申请号：US985
申请日：1993-01-06
申请人： James E. Aysta
发明人： James E. Aysta
IPC分类号： B01D29/05 , B01L9/00
CPC分类号： B01L3/50255 , B01L2200/04 , B01L2400/049 , B01L9/523
摘要： A multi-well filtration apparatus is provided that has a housing, a multi-well filtration plate, and a pivotable member. The pivotable member secures the multi-well filtration plate to the housing and is associated with a resilient member. When the multi-well filtration plate is pressed against the pivotable member, it pivots, and the resilient member compresses to allow the pivotable member to instantaneously engage the multi-well filtration plate to secure it to the housing. The pivotable member can quickly release the multi-well filtration plate by simply exerting a force on a surface of the pivotable member.
摘要翻译：提供了具有壳体，多孔过滤板和可枢转构件的多孔过滤装置。可枢转构件将多孔过滤板固定到壳体并且与弹性构件相关联。当多孔过滤板被压靠在可枢转的构件上时，其枢转，并且弹性构件压缩以允许可枢转构件瞬时接合多孔过滤板以将其固定到壳体。可枢转构件可以通过简单地在可枢转构件的表面上施加力来快速地释放多孔过滤板。

4. 发明授权

US4936849A Intraocular lens 失效
标题翻译：人工晶状体
公开(公告)号：US4936849A
公开(公告)日：1990-06-26
申请号：US168394
申请日：1988-03-15
申请人： Randall L. Knoll , James E. Aysta , Wilhelm Lewon
发明人： Randall L. Knoll , James E. Aysta , Wilhelm Lewon
IPC分类号： A61F2/16
CPC分类号： A61F2/1613 , A61F2002/1686 , Y10T29/49945
摘要： Disclosed is an intraocular lens comprising a lens element and a plurality of haptics extending therefrom, at least one of the haptics having an anchoring filament with an enlarged complete or partial mushroom-shaped end fixedly disposed inside a passage in the lens element. Also disclosed is a method for fixing a haptic having an anchoring filament to a lens element in a soft intraocular lens comprising the steps of (a) forming in the lens element a passage having a width that is less than the greatest width of the anchoring filament, (b) lubricating the anchoring filament of the haptic, the passage in the lens element, or both, (c) inserting the anchoring filament end-first into the passage, and (d) washing the intraocular lens to remove the lubricant.

5. 发明授权

US4444449A Electrical connector 失效
标题翻译：电连接器
公开(公告)号：US4444449A
公开(公告)日：1984-04-24
申请号：US346486
申请日：1982-02-08
申请人： James E. Aysta , Geoffrey Gibson , Rainer A. Tuukkanen
发明人： James E. Aysta , Geoffrey Gibson , Rainer A. Tuukkanen
IPC分类号： H01R4/24 , H01R13/38
CPC分类号： H01R4/2429
摘要： An electrical connector for non-prestripped wires has a lower housing part (1) with wire guides, each comprising a double channel consisting of an upper introduction channel (47) having a cross-section suited for the introduction of a wire (7) and therebelow a parallel clamping channel (49) connected to the introduction channel by a constricted transition slit (51). A projection provided at an upper housing forces the wire at least partly into and through the transition slit (51) and into a recess (37) in the lower housing part (1) upon telescoping of the upper housing part into the lower housing part, thereby clamping the wire to strain relieve it.
摘要翻译：用于非预绞线的电连接器具有带导线器的下壳体部分（1），每个包括一个双通道，该双通道由上导入通道（47）组成，上引导通道（47）具有适于引入导线（7）的横截面，在下面的平行夹持通道（49）通过收缩的过渡狭缝（51）连接到引入通道。设置在上壳体处的突起在将上壳体部件伸缩到下壳体部分中时迫使线材至少部分地进入并穿过过渡狭缝（51）并进入下壳体部分（1）中的凹部（37）从而将电线夹紧以减轻其损伤。

6. 发明授权

US4010994A Connector encapsulating housing 失效
标题翻译：连接器封装外壳
公开(公告)号：US4010994A
公开(公告)日：1977-03-08
申请号：US586502
申请日：1975-06-12
申请人： James E. Aysta
发明人： James E. Aysta
IPC分类号： H02G15/00 , H02G15/10 , H01R13/44
CPC分类号： H02G15/10 , H02G15/003
摘要： A housing used for encapsulating an electrical connector having internal passageways extending between opposite ends. A socket in the housing which conforms to the connector is filled with a quantity of viscous electrically insulating water restricting encapsulating material, and the connector is pressed endways into the socket via levers on the housing so that the encapsulating material is forced into and extruded through the passageways to completely fill the interstices in the connector.

7. 发明授权

US08609330B2 Live Bioload detection using microparticles 有权
标题翻译：使用微粒进行活体生物负载检测
公开(公告)号：US08609330B2
公开(公告)日：2013-12-17
申请号：US13142290
申请日：2009-12-31
申请人： Raj Rajagopal , Kurt J. Halverson , Manjiri T. Kshirsagar , James E. Aysta
发明人： Raj Rajagopal , Kurt J. Halverson , Manjiri T. Kshirsagar , James E. Aysta
IPC分类号： C12Q1/00 , C12Q1/02 , C12Q1/04
CPC分类号： C12Q1/04 , A61B10/0045 , A61B10/02 , B01L3/5082 , B01L2200/026 , B01L2200/10 , C12M23/08 , C12M23/32 , C12M23/34 , C12M33/02 , G01N33/56916 , G01N2333/245
摘要： The present invention provides methods to concentrate cells onto microparticles, to concentrate the microparticles, and to detect the cells. The present invention also includes unitary sample preparation and detection devices to be used in accordance with the methods.
摘要翻译：本发明提供了将细胞浓缩到微粒上，浓缩微粒并检测细胞的方法。本发明还包括根据该方法使用的单一样品制备和检测装置。

8. 发明申请

US20110053785A1 SAMPLE PROCESSING DEVICES 有权
标题翻译：样品加工装置
公开(公告)号：US20110053785A1
公开(公告)日：2011-03-03
申请号：US12943389
申请日：2010-11-10
申请人： WILLIAM BEDINGHAM , James E. Aysta , Barry W. Robole , Kenneth B. Wood
发明人： WILLIAM BEDINGHAM , James E. Aysta , Barry W. Robole , Kenneth B. Wood
IPC分类号： C40B30/00
CPC分类号： B01L3/502738 , B01L7/52 , B01L2300/0816 , B01L2300/0864 , B01L2400/0655 , Y10T436/25 , Y10T436/2575
摘要： Methods and devices for thermal processing of multiple samples at the same time are disclosed. The sample processing devices provide process arrays that include conduits useful in distributing sample materials to a group of process chambers located in fluid communication with the main conduits. The sample processing devices may include one or more of the following features in various combinations: deformable seals, process chambers connected to the main conduit by feeder conduits exiting the main conduit at offset locations, U-shaped loading chambers, and a combination of melt bonded and adhesively bonded areas.
摘要翻译：同时公开了多个样品的热处理方法和装置。样品处理装置提供处理阵列，其包括用于将样品材料分配到与主管道流体连通的一组处理室的管道。样品处理装置可以包括以下各种组合中的一个或多个以下特征：可变形密封件，通过在偏移位置处离开主管道的进料管道连接到主管道的处理室，U形加载室和熔融粘合的组合和粘合区域。

9. 发明申请

US20090263280A1 SYSTEMS FOR USING SAMPLE PROCESSING DEVICES 有权
标题翻译：使用样品加工装置的系统
公开(公告)号：US20090263280A1
公开(公告)日：2009-10-22
申请号：US12491959
申请日：2009-06-25
申请人： William Bedingham , James E. Aysta , Barry W. Robole
发明人： William Bedingham , James E. Aysta , Barry W. Robole
IPC分类号： G01N35/00
CPC分类号： B01L3/50851 , B01L7/52 , B01L7/54 , B01L9/523 , B01L2300/0803 , B01L2300/1861 , G01N35/025 , G01N2035/00326 , Y10T436/111666
摘要： Sample processing systems for processing sample materials located in sample processing devices that are separate from the system are disclosed. The sample processing systems include a rotating base plate with raised and/or non-planar thermal structures on which the sample processing devices are located during operation of the systems. The systems may also include structure to urge the sample processing devices against the base plate and thermal structures.
摘要翻译：公开了用于处理位于与系统分开的样品处理装置中的样品的样品处理系统。样品处理系统包括具有凸起和/或非平面热结构的旋转底板，其中样品处理装置在系统的操作期间位于其上。该系统还可以包括将样品处理装置推靠在基板和热结构上的结构。

10. 发明授权

US4163596A Electrical connector 失效
标题翻译：电连接器
公开(公告)号：US4163596A
公开(公告)日：1979-08-07
申请号：US872825
申请日：1978-01-27
申请人： James E. Aysta , Dewain R. Goff
发明人： James E. Aysta , Dewain R. Goff
IPC分类号： H01R4/24 , H01R24/00 , H01R9/08
CPC分类号： H01R4/2429
摘要： A connector for insulated electrical wires in which a body of insulating material has a wire connection well formed into one surface and receives a slotted, flat plate, electrical contact element. A wire retention well is formed adjacent the wire connection well and is joined to the wire connection well by a passageway aligned with the slot in the contact element. The passageway is constricted to engage the insulation of a wire forced into the slot of the contact element in the wire connection well through the passageway and out of the wire retention well to electrically connect the wire to the contact element while providing strain relief for the wire in the passageway.
摘要翻译：一种用于绝缘电线的连接器，其中绝缘材料体具有良好地形成在一个表面中并且接收开槽的平板，电接触元件的导线连接。电线保持孔邻近电线连接井形成，并且通过与接触元件中的狭槽对准的通道连接到电线连接井。通道被收缩以将被迫进入导线连接孔中的接触元件的槽中的电线的绝缘通过通道和电线保持孔接合，以将电线电连接到接触元件，同时为电线提供应变消除在通道。

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