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1. 发明授权

US5842994A Multifunction intraluminal ultrasound catheter having a removable core with maximized transducer aperture 失效
标题翻译：多功能腔内超声导管具有最大化的换能器孔径的可移除的核心
公开(公告)号：US5842994A
公开(公告)日：1998-12-01
申请号：US886882
申请日：1997-07-02
申请人： Harm TenHoff , Isaac Ostrovsky , James D. Koger
发明人： Harm TenHoff , Isaac Ostrovsky , James D. Koger
IPC分类号： A61B8/12 , A61B8/00
CPC分类号： A61B8/12 , A61B8/445 , A61B8/4461
摘要： A multi-function intraluminal ultrasound catheter assembly includes an axially disposed lumen having at least a first portion with a flat inner wall forming a "D-shaped" cross-section. An acoustic imaging window having a circular cross-section is connected to a distal end of the catheter assembly, wherein the cross-sectional dimension of the D-shaped portion of the lumen that extends from the flat inner wall is less that the available inner diameter of the imaging window. A flexible drive-shaft extends through the lumen and is connected to a transducer housing disposed in the acoustic imaging window area, the transducer housing having a substantially "D-shaped" outer perimeter, wherein the drive-shaft and connected transducer housing may thereby be retracted from the catheter assembly by first rotating the transducer housing until its D-shaped outer perimeter is substantially oriented with the D-shaped cross-section of the lumen. In a preferred embodiment, the transducer housing also includes a longitudinally disposed transducer mounting section configured such that the active surface of a transducer mounted therein is generally aligned across the maximal inner diameter of the acoustic imaging window.
摘要翻译：多功能腔内超声导管组件包括轴向设置的腔，其具有至少第一部分，其具有形成“D”形横截面的平坦内壁。具有圆形横截面的声学成像窗口连接到导管组件的远端，其中从平坦内壁延伸的内腔的D形部分的横截面尺寸小于可用内径的成像窗口。灵活的驱动轴延伸穿过内腔并且连接到设置在声学成像窗口区域中的换能器壳体，换能器壳体具有基本上“D”形的外周边，其中驱动轴和连接的换能器壳体可以由此通过首先旋转换能器壳体直到其D形外周边基本上与内腔的D形横截面取向而从导管组件缩回。在优选实施例中，换能器壳体还包括纵向设置的换能器安装部分，其配置成使得安装在其中的换能器的主动表面大致对准在声学成像窗口的最大内径之间。

2. 发明授权

US5984871A Ultrasound transducer with extended focus 失效
标题翻译：超声波换能器具有延长的焦距
公开(公告)号：US5984871A
公开(公告)日：1999-11-16
申请号：US909577
申请日：1997-08-12
申请人： Harm TenHoff , James D. Koger
发明人： Harm TenHoff , James D. Koger
IPC分类号： A61B8/12 , G10K11/30
CPC分类号： A61B8/445 , G10K11/30 , A61B8/12
摘要： An ultrasound transducer having an extended focus for enabling an ultrasound imaging catheter to image features at a distance from the transducer with a high resolution and a high penetration depth. The ultrasound transducer is configured such that the acoustic path-length from the periphery of the transducer is increased relative to the acoustic path-length from the center of the transducer thereby increasing the transition length and focal length of the transducer. The ultrasound transducer may include an acoustic element having a convex surface on a side which transmits and receives ultrasound waves. An acoustic backing material may be attached to the acoustic element opposite the side where ultrasound waves are transmitted and received, and an acoustic matching layer may be provided on the convex surface of the acoustic element. The acoustic matching layer may have a substantially uniform thickness such that it also has a convex outer surface. The radius of curvature of the convex surface of the acoustic transducer element will determine the focal length for a given size and frequency of operation of the ultrasound transducer.
摘要翻译：具有扩展焦点的超声换能器，其能够使超声成像导管以与高分辨率和高穿透深度的换能器一定距离的特征成像。超声波换能器被配置为使得来自换能器周边的声路长度相对于从换能器中心的声路长度增加，从而增加换能器的转换长度和焦距。超声波换能器可以包括在发送和接收超声波的一侧具有凸表面的声学元件。声学衬垫材料可以附接到声学元件，该声学元件与超声波被传送和接收的一侧相反，并且声学匹配层可以设置在声学元件的凸形表面上。声匹配层可以具有基本均匀的厚度，使得它也具有凸的外表面。声换能器元件的凸表面的曲率半径将确定超声换能器的给定尺寸和操作频率的焦距。

3. 发明授权

US6106474A Aerogel backed ultrasound transducer 失效
公开(公告)号：US6106474A
公开(公告)日：2000-08-22
申请号：US972962
申请日：1997-11-19
申请人： James D. Koger , Isaac Ostrovsky
发明人： James D. Koger , Isaac Ostrovsky
IPC分类号： B06B1/06 , A61B8/14
CPC分类号： B06B1/0674
摘要： An ultrasound transducer having an acoustic backing layer made of an aerogel material is disclosed. The ultrasound transducer comprises an acoustic element for transmitting and receiving ultrasound waves. An aerogel acoustic backing layer is bonded to the back side of the acoustic element. A matching layer may be attached to the front side of the acoustic element. The ultrasound transducer may be electrically connected using electrodes directly connected to the acoustic element. Alternatively, the aerogel acoustic backing may be coated with a metalized layer or doped so that it is electrically conductive. Then, the electrodes may be connected directly to the aerogel acoustic backing.

4. 发明授权

US06475151B2 Aerogel backed ultrasound transducer 失效
标题翻译：气凝胶支持超声波传感器
公开(公告)号：US06475151B2
公开(公告)日：2002-11-05
申请号：US09835145
申请日：2001-04-13
申请人： James D. Koger , Isaac Ostrovsky
发明人： James D. Koger , Isaac Ostrovsky
IPC分类号： A61B814
CPC分类号： B06B1/0674
摘要： An ultrasound transducer having an acoustic backing layer made of an aerogel material is disclosed. The ultrasound transducer comprises an acoustic element for transmitting and receiving ultrasound waves. An aerogel acoustic backing layer is bonded to the back side of the acoustic element. A matching layer may be attached to the front side of the acoustic element. The ultrasound transducer may be electrically connected using electrodes directly connected to the acoustic element. Alternatively, the aerogel acoustic backing may be coated with a metalized layer or doped so that it is electrically conductive. Then, the electrodes may be connected directly to the aerogel acoustic backing.
摘要翻译：公开了一种具有由气凝胶材料制成的声学背衬层的超声换能器。超声波换能器包括用于发射和接收超声波的声学元件。气凝胶背衬层结合到声学元件的背面。匹配层可以附接到声学元件的前侧。可以使用直接连接到声学元件的电极来电连接超声换能器。或者，气凝胶声学背衬可以涂覆有金属化层或掺杂以使其具有导电性。然后，电极可以直接连接到气凝胶声学背衬。

5. 发明授权

US06280388B1 Aerogel backed ultrasound transducer 失效
标题翻译：气凝胶支持超声波传感器
公开(公告)号：US06280388B1
公开(公告)日：2001-08-28
申请号：US09050543
申请日：1998-03-30
申请人： James D. Koger , Isaac Ostrovsky
发明人： James D. Koger , Isaac Ostrovsky
IPC分类号： A61B814
CPC分类号： B06B1/0674
摘要： An ultrasound transducer having an acoustic backing layer made of an aerogel material is disclosed. The ultrasound transducer comprises an acoustic element for transmitting and receiving ultrasound waves. An aerogel acoustic backing layer is bonded to the back side of the acoustic element. A matching layer may be attached to the front side of the acoustic element. The ultrasound transducer may be electrically connected using electrodes directly connected to the acoustic element. Alternatively, the aerogel acoustic backing may be coated with a metalized layer or doped so that it is electrically conductive. Then, the electrodes may be connected directly to the aerogel acoustic backing.
摘要翻译：公开了一种具有由气凝胶材料制成的声学背衬层的超声换能器。超声波换能器包括用于发射和接收超声波的声学元件。气凝胶背衬层结合到声学元件的背面。匹配层可以附接到声学元件的前侧。可以使用直接连接到声学元件的电极来电连接超声换能器。或者，气凝胶声学背衬可以涂覆有金属化层或掺杂以使其具有导电性。然后，电极可以直接连接到气凝胶声学背衬。

6. 发明授权

US08005529B2 Systems and methods for internal tissue penetration 有权
标题翻译：内部组织穿透的系统和方法
公开(公告)号：US08005529B2
公开(公告)日：2011-08-23
申请号：US12749234
申请日：2010-03-29
申请人： Kamal Ramzipoor , James D. Koger , Gopal Chopra
发明人： Kamal Ramzipoor , James D. Koger , Gopal Chopra
IPC分类号： A61B5/05
CPC分类号： A61B1/00087 , A61B1/00082 , A61B1/00135 , A61B1/3132 , A61B5/0066 , A61B5/0084 , A61B8/12 , A61B8/445 , A61B17/32002 , A61B17/3478 , A61B2017/00247 , A61B2017/22075 , A61B2017/22077 , A61B2017/22078 , A61B2017/320004 , A61B2018/00392 , A61B2090/378 , A61B2090/3782
摘要： A medical system includes an inner core and an imager located at the distal end of the inner core, wherein the imager is extendable from within an elongated tubular member and configured to penetrate a body tissue within a living body. The elongated tubular member is configured to slideably receive the inner core. The inner core is configured to rotate radially around a longitudinal axis of the elongated member, and the imager can be configured to image a body tissue and output an image signal to an imaging system communicatively coupled with the imager. The imaging system is configured to generate an image of the body tissue from the image signal of the imager when the imager is rotated and placed into contact with the body tissue.
摘要翻译：医疗系统包括内芯和位于内芯的远端的成像器，其中成像器可从细长的管状构件中延伸并构造成穿透活体内的身体组织。细长管状构件构造成可滑动地容纳内芯。内芯构造成围绕细长构件的纵向轴线径向旋转，并且成像器可以被配置为对身体组织成像并将图像信号输出到与成像器通信地耦合的成像系统。成像系统被配置为当成像器旋转并与身体组织接触时从成像器的图像信号生成身体组织的图像。

7. 发明授权

US06529760B2 Intravascular imaging guidewire 有权
标题翻译：血管内成像导丝
公开(公告)号：US06529760B2
公开(公告)日：2003-03-04
申请号：US09876717
申请日：2001-06-06
申请人： Anthony J. Pantages , William Martin Belef , Lawrence D. Wasicek , Donald S. Mamayek , James D. Koger , Steven Nelson Roe
发明人： Anthony J. Pantages , William Martin Belef , Lawrence D. Wasicek , Donald S. Mamayek , James D. Koger , Steven Nelson Roe
IPC分类号： A61B500
CPC分类号： A61B8/12 , A61B8/445 , A61B8/4461 , A61B8/4488 , A61M25/09
摘要： An intravascular imaging guidewire which can accomplish longitudinal translation of an imaging plane allowing imaging, by acoustic other high quality imaging energy, of an axial length of a region of interest without moving the guidewire. The imaging guidewire comprises a body in the form of a flexible elongate tubular member. An elongate flexible imaging core is slidably received within the body. The imaging core includes a shaft having an imaging device mounted on its distal end. The body and the imaging core are cooperatively constructed to enable axial translation of the imaging core and imaging device relative to the body. The body has a transparent distal portion extending an axial length over which axially translatable imaging may be performed. The imaging guidewire has a maximum diameter over its entire length sized to be received within a guidewire lumen of an intravascular catheter.
摘要翻译：可以实现成像平面的纵向平移的血管内成像导丝，允许感兴趣区域的轴向长度的声学其他高质量成像能量，而不移动导丝。成像导丝包括柔性细长管状构件形式的主体。细长的柔性成像芯可滑动地容纳在体内。成像芯包括具有安装在其远端上的成像装置的轴。协同构造身体和成像芯，以使得成像芯和成像装置相对于身体能够轴向平移。主体具有延伸轴向长度的透明远端部分，可在其上执行可轴向平移的成像。成像导丝在其整个长度上具有最大直径，其尺寸被设计成容纳在血管内导管的导丝管腔内。

8. 发明授权

US08187194B2 Method of mounting a transducer to a driveshaft 有权
标题翻译：将传感器安装到驱动轴上的方法
公开(公告)号：US08187194B2
公开(公告)日：2012-05-29
申请号：US12793115
申请日：2010-06-03
申请人： Manuel Serrano , James D. Koger
发明人： Manuel Serrano , James D. Koger
IPC分类号： A61B8/00
CPC分类号： A61B8/12 , A61B8/445 , A61B8/4461
摘要： A method of mounting a transducer to a driveshaft which eliminates the need for a transducer housing, the improved method directly attaches the transducer to a rigid distal tip of a driveshaft which is part of a rotatable imaging core of a catheter assembly. The method contemplates heat treating the distal tip of the driveshaft to make it rigid, machining the distal tip to be dimensioned to hold the transducer, and attaching the transducer to the distal tip by clamping, crimping, or an adhesive.
摘要翻译：一种将换能器安装到驱动轴上的方法，其消除了对换能器壳体的需要，该改进的方法直接将换能器附接到作为导管组件的可旋转成像芯的一部分的驱动轴的刚性远端。该方法考虑热处理驱动轴的远端以使其刚性，加工远侧末端以确定尺寸以保持换能器，并且通过夹紧，压接或粘合剂将换能器附接到远侧末端。

9. 发明授权

US06261246B1 Intravascular imaging guidewire 有权
标题翻译：血管内成像导丝
公开(公告)号：US06261246B1
公开(公告)日：2001-07-17
申请号：US09162090
申请日：1998-09-28
申请人： Anthony J. Pantages , William Martin Belef , Lawrence D. Wasicek , Donald S. Mamayek , James D. Koger , Steven Nelson Roe
发明人： Anthony J. Pantages , William Martin Belef , Lawrence D. Wasicek , Donald S. Mamayek , James D. Koger , Steven Nelson Roe
IPC分类号： A61B812
CPC分类号： A61B8/12 , A61B8/445 , A61B8/4461 , A61B8/4488 , A61M25/09
摘要： An intravascular imaging guidewire which can accomplish longitudinal translation of an imaging plane allowing imaging of an axial length of a region of interest without moving the guidewire. The imaging guidewire comprises a body in the form of a flexible elongate tubular member. An elongate flexible imaging core is slidably received within the body. The imaging core includes a shaft having an imaging device mounted on its distal end. The body and the imaging core are cooperatively constructed to enable axial translation of the imaging core and imaging device relative to the body. The body has a transparent distal portion extending an axial length over which axially translatable imaging may be performed. The imaging guidewire has a maximum diameter over its entire length sized to be received within a guidewire lumen of an intravascular catheter.
摘要翻译：血管内成像导丝，其可以实现成像平面的纵向平移，允许在不移动导丝的情况下成像感兴趣区域的轴向长度。成像导丝包括柔性细长管状构件形式的主体。细长的柔性成像芯可滑动地容纳在体内。成像芯包括具有安装在其远端上的成像装置的轴。协同构造身体和成像芯，以使得成像芯和成像装置相对于身体能够轴向平移。主体具有延伸轴向长度的透明远端部分，可在其上执行可轴向平移的成像。成像导丝在其整个长度上具有最大直径，其尺寸被设计成容纳在血管内导管的导丝管腔内。

10. 发明授权

US06371915B1 One-twelfth wavelength impedence matching transformer 失效
标题翻译：第十二波长阻抗匹配变压器
公开(公告)号：US06371915B1
公开(公告)日：2002-04-16
申请号：US09432914
申请日：1999-11-02
申请人： James D. Koger , Robert W. Crowley
发明人： James D. Koger , Robert W. Crowley
IPC分类号： A61B800
CPC分类号： G10K11/02 , Y10T29/42
摘要： An ultrasound transducer including a one-twelfth wavelength impedance matching transformer and methods of manufacturing and using the same. The transducer comprises a transducer element for transmitting and receiving ultrasound waves, a first impedance matching layer, and a second impedance matching layer. The transducer element has a transmitting/receiving surface, an impedance, and a thickness of substantially one-half wavelength of an ultrasound wave generated thereby. The first impedance matching layer is formed on the transmitting/receiving surface of the transducer element and has a thickness of substantially one-twelfth wavelength of the ultrasound wave travelling therein. The second impedance matching layer is formed on a selected surface of the first impedance matching layer and has a thickness of substantially one-twelfth wavelength of the ultrasound passing therethrough. An impedance of the first impedance matching layer is substantially equal to an impedance of an operating medium; whereas, an impedance of the second impedance matching layer is substantially equal to the impedance of the transducer element.
摘要翻译：包括第十二波长阻抗匹配变压器的超声波换能器及其制造和使用方法。换能器包括用于发射和接收超声波的换能器元件，第一阻抗匹配层和第二阻抗匹配层。换能器元件具有由其产生的超声波的发射/接收表面，阻抗和基本上为二分之一波长的厚度。第一阻抗匹配层形成在换能器元件的发送/接收表面上，并且具有在其中传播的超声波的基本上十二分之一波长的厚度。第二阻抗匹配层形成在第一阻抗匹配层的选定表面上，并且具有通过其的超声波的基本上第十二分之一波长的厚度。第一阻抗匹配层的阻抗基本上等于操作介质的阻抗; 而第二阻抗匹配层的阻抗基本上等于换能器元件的阻抗。

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