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1. 发明授权

US06419827B1 Purification apparatus and method 失效
标题翻译：净化装置及方法
公开(公告)号：US06419827B1
公开(公告)日：2002-07-16
申请号：US09552301
申请日：2000-04-18
申请人： Donald R. Sandell , Kevin S. Bodner , Mark Borodkin , Mark Oldham , Jon Hoshizaki
发明人： Donald R. Sandell , Kevin S. Bodner , Mark Borodkin , Mark Oldham , Jon Hoshizaki
IPC分类号： B01D6300
CPC分类号： B01L3/50255 , B01D61/18 , B01L3/5025 , B01L2400/049 , G01N35/0099 , G01N35/028 , G01N35/1074 , G01N2035/00485 , G01N2035/102
摘要： The invention includes a filtration apparatus for processing a plurality of fluid samples into sample wells is provided. In one embodiment, the filtration apparatus includes a purification tray and a sample well tray with a plurality of sample wells. The purification tray includes a filter plate having a plurality of columns with discharge openings at the bottom thereof, at least one filter positioned in the columns of the filter plate for filtering the fluid samples as they pass therethrough, a heat plate positioned adjacent the columns of the filter plate, and a vent plate positioned below the heat plate. The heat plate is configured for transferring heat to the columns of the filter plate. The vent plate includes vents for permitting aerosols from the sample wells of the sample well tray to escape. A sample well tray with a plurality of the sample wells is positioned so that the sample wells align with the discharge openings of the filter plate columns to receive the liquid sample therein.
摘要翻译：本发明提供了一种用于将多个流体样品加工成样品孔的过滤装置。在一个实施例中，过滤装置包括净化盘和具有多个样品孔的样品井托盘。净化盘包括一个过滤板，该过滤板具有多个在其底部具有排放口的柱，至少一个过滤器，定位在过滤板的列中，用于在流体样品通过过滤器时对其进行过滤，过滤板和位于加热板下方的通风板。加热板被配置为将热量传递到过滤板的列。通风板包括用于允许来自样品井托盘的样品井的气溶胶逸出的通风口。定位具有多个样品孔的样品孔盘，使得样品孔与过滤板柱的排出口对准以在其中接收液体样品。

2. 发明授权

US07019267B2 Sample tray heater module 失效
标题翻译：样品盘加热器模块
公开(公告)号：US07019267B2
公开(公告)日：2006-03-28
申请号：US11120797
申请日：2005-05-03
申请人： Todd A. Weinfield , Gary Lim , Donald R. Sandell , Kevin S. Bodner , Mark Borodkin , Mark Oldham , Jon Hoshizaki
发明人： Todd A. Weinfield , Gary Lim , Donald R. Sandell , Kevin S. Bodner , Mark Borodkin , Mark Oldham , Jon Hoshizaki
IPC分类号： H05B3/22 , C12M1/38 , B01L7/00
CPC分类号： B01L3/50255 , B01D61/18 , B01J2219/00288 , B01J2219/00313 , B01J2219/00319 , B01J2219/00335 , B01J2219/00416 , B01J2219/00418 , B01J2219/00423 , B01L7/52 , B01L2200/025 , B01L2200/0631 , B01L2200/0689 , B01L2200/141 , B01L2300/0829 , B01L2300/1805 , B01L2400/049 , G01N1/4077 , G01N35/0099 , G01N35/028 , G01N35/1074 , G01N2035/00485 , G01N2035/102 , Y10T436/25375
摘要： A heater module is described that includes a heat distribution plate including a bottom portion having first and second sides and a plurality of projections extending away from one of the sides. A heat source is provided for heating the heat distribution plate, and, optionally, a heating tray can be used to receive the heat source and heat distribution plate. The heater module is adapted to engage a sample purification tray having a plurality of purification and/or discharge columns which can extend through openings in the heater module and direct a sample into a sample receiving tray. Methods of heating samples using the heater module are also described.
摘要翻译：描述了一种加热器模块，其包括配热板，该散热板包括具有第一和第二侧面的底部以及远离其中一个侧面延伸的多个突起。提供了用于加热分布板的热源，并且可选地，加热盘可以用于接收热源和散热板。加热器模块适于接合具有多个净化和/或排出柱的样品净化盘，其可以延伸穿过加热器模块中的开口并将样品引导到样品接收托盘中。还描述了使用加热器模块加热样品的方法。

3. 发明授权

US07452510B2 Manually-operable multi-well microfiltration apparatus and method 有权
标题翻译：手动操作的多孔微滤装置及方法
公开(公告)号：US07452510B2
公开(公告)日：2008-11-18
申请号：US11338254
申请日：2006-01-24
申请人： Todd A. Weinfield , Gary Lim , Donald R. Sandell , Kevin S. Bodner , Mark Borodkin , Mark Oldham , Jon Hoshizaki
发明人： Todd A. Weinfield , Gary Lim , Donald R. Sandell , Kevin S. Bodner , Mark Borodkin , Mark Oldham , Jon Hoshizaki
IPC分类号： B01L11/00 , B01L3/00 , B01D63/00 , B65B43/42
CPC分类号： B01L3/50255 , B01D61/18 , B01J2219/00288 , B01J2219/00313 , B01J2219/00319 , B01J2219/00335 , B01J2219/00416 , B01J2219/00418 , B01J2219/00423 , B01L7/52 , B01L2200/025 , B01L2200/0631 , B01L2200/0689 , B01L2200/141 , B01L2300/0829 , B01L2300/1805 , B01L2400/049 , G01N1/4077 , G01N35/0099 , G01N35/028 , G01N35/1074 , G01N2035/00485 , G01N2035/102 , Y10T436/25375
摘要： A multi-well microfiltration apparatus and method are provided and feature a manual touch-off system for transferring pendent drops hanging from discharge-conduits of a discharge-conduit array to respective receiving wells or receiving holes of a corresponding receiving array, with minimum or no cross-contamination between the discharge conduits, or the receiving wells or receiving holes. The manual touch-off is achieved by manually shifting a carriage that supports one of the arrays, into a position whereat pendent drops of fluid hanging from the distal ends of the discharge conduits contact the inner sidewalls of the corresponding receiving wells or receiving holes of the receiving array.
摘要翻译：提供了一种多孔微滤装置和方法，其特征在于一种手动触发系统，用于将从排放管阵列的排放管道悬挂的悬挂液滴转移到相应接收孔的相应接收孔或接收孔的最小或不排放管道或接收井或接收孔之间的交叉污染。手动触发是通过将支撑其中一个阵列的托架手动地移动到从排出管道的远端悬挂的悬挂液滴与相应的接收井的内侧壁接触的位置或接收孔的接收孔接收阵列。

4. 发明授权

US06906292B2 Sample tray heater module 有权
标题翻译：样品盘加热器模块
公开(公告)号：US06906292B2
公开(公告)日：2005-06-14
申请号：US10359665
申请日：2003-02-06
申请人： Todd A. Weinfield , Gary Lim , Donald R. Sandell , Kevin S. Bodner , Mark Borodkin , Mark Oldham , Jon Hoshizaki
发明人： Todd A. Weinfield , Gary Lim , Donald R. Sandell , Kevin S. Bodner , Mark Borodkin , Mark Oldham , Jon Hoshizaki
IPC分类号： B01L99/00 , B01D61/18 , B01L3/00 , B01L7/00 , G01N35/00 , G01N35/02 , G01N35/10 , C12M1/38 , H05B3/22
CPC分类号： B01L3/50255 , B01D61/18 , B01J2219/00288 , B01J2219/00313 , B01J2219/00319 , B01J2219/00335 , B01J2219/00416 , B01J2219/00418 , B01J2219/00423 , B01L7/52 , B01L2200/025 , B01L2200/0631 , B01L2200/0689 , B01L2200/141 , B01L2300/0829 , B01L2300/1805 , B01L2400/049 , G01N1/4077 , G01N35/0099 , G01N35/028 , G01N35/1074 , G01N2035/00485 , G01N2035/102 , Y10T436/25375
摘要： A heater module is described that includes a heat distribution plate including a bottom portion having first and second sides and a plurality of projections extending away from one of the sides. A heat source is provided for heating the heat distribution plate, and, optionally, a heating tray can be used to receive the heat source and heat distribution plate. The heater module is adapted to engage a sample purification tray having a plurality of purification and/or discharge columns which can extend through openings in the heater module and direct a sample into a sample receiving tray. Methods of heating samples using the heater module are also described.
摘要翻译：描述了一种加热器模块，其包括配热板，该散热板包括具有第一和第二侧面的底部以及远离其中一个侧面延伸的多个突起。提供了用于加热分布板的热源，并且可选地，加热盘可以用于接收热源和散热板。加热器模块适于接合具有多个净化和/或排出柱的样品净化盘，其可以延伸穿过加热器模块中的开口并将样品引导到样品接收托盘中。还描述了使用加热器模块加热样品的方法。

5. 发明授权

US08373854B2 Luminescence reference standards 有权
标题翻译：发光参考标准
公开(公告)号：US08373854B2
公开(公告)日：2013-02-12
申请号：US12813389
申请日：2010-06-10
申请人： J. Michael Phillips , Kevin S. Bodner , Aldrich N. K. Lau , Steven J. Boege , Mark F. Oldham , Donald R. Sandell , David H. Tracy
发明人： J. Michael Phillips , Kevin S. Bodner , Aldrich N. K. Lau , Steven J. Boege , Mark F. Oldham , Donald R. Sandell , David H. Tracy
IPC分类号： G01N1/10
CPC分类号： G01N21/278 , B82Y15/00 , G01J1/10 , G01N21/01 , G01N21/4785 , G01N21/6452 , G01N21/76 , G01N2201/06113 , G01N2201/0612 , G01N2201/062 , G01N2201/0691 , G01N2201/0697 , Y10S977/943 , Y10S977/949
摘要： The present teachings provide for systems, and components thereof, for detecting and/or analyzing light. These systems can include, among others, optical reference standards utilizing luminophores, such as nanocrystals, for calibrating, validating, and/or monitoring light-detection systems, before, during, and/or after sample analysis.
摘要翻译：本教导提供了用于检测和/或分析光的系统及其组件。这些系统尤其可以包括在样品分析之前，期间和/或之后利用发光体（例如纳米晶体）用于校准，验证和/或监测光检测系统的光学参考标准。

6. 发明授权

US07480042B1 Luminescence reference standards 有权
标题翻译：发光参考标准
公开(公告)号：US07480042B1
公开(公告)日：2009-01-20
申请号：US11173609
申请日：2005-06-30
申请人： J. Michael Phillips , Aldrich N. K. Lau , Mark F. Oldham , Kevin S. Bodner , Steven J. Boege , Donald R. Sandell , David H. Tracy
发明人： J. Michael Phillips , Aldrich N. K. Lau , Mark F. Oldham , Kevin S. Bodner , Steven J. Boege , Donald R. Sandell , David H. Tracy
IPC分类号： G01J1/10
CPC分类号： G01N21/278 , B82Y15/00 , G01J1/10 , G01N21/01 , G01N21/4785 , G01N21/6452 , G01N21/76 , G01N2201/06113 , G01N2201/0612 , G01N2201/062 , G01N2201/0691 , G01N2201/0697 , Y10S977/943 , Y10S977/949
摘要： Systems, and components thereof, for detecting and/or analyzing light. These systems can include, among others, optical reference standards for calibrating, validating, and/or monitoring light-detection systems, before, during, and/or after sample analysis.
摘要翻译：系统及其组件，用于检测和/或分析光。样品分析之前，期间和/或之后，这些系统可以包括用于校准，验证和/或监测光检测系统的光学参考标准。

7. 发明申请

US20110085168A1 Luminescence Reference Standards 有权
标题翻译：发光参考标准
公开(公告)号：US20110085168A1
公开(公告)日：2011-04-14
申请号：US12813389
申请日：2010-06-10
申请人： J. Michael Phillips , Aldrich N.K. Lau , Mark F. Oldham , Kevin S. Bodner , Steven J. Boege , Donald R. Sandell , David H. Tracy
发明人： J. Michael Phillips , Aldrich N.K. Lau , Mark F. Oldham , Kevin S. Bodner , Steven J. Boege , Donald R. Sandell , David H. Tracy
IPC分类号： G01J1/10 , G01B11/00 , B82Y99/00
CPC分类号： G01N21/278 , B82Y15/00 , G01J1/10 , G01N21/01 , G01N21/4785 , G01N21/6452 , G01N21/76 , G01N2201/06113 , G01N2201/0612 , G01N2201/062 , G01N2201/0691 , G01N2201/0697 , Y10S977/943 , Y10S977/949
摘要： The present teachings provide for systems, and components thereof, for detecting and/or analyzing light. These systems can include, among others, optical reference standards utilizing luminophores, such as nanocrystals, for calibrating, validating, and/or monitoring light-detection systems, before, during, and/or after sample analysis.
摘要翻译：本教导提供了用于检测和/或分析光的系统及其组件。这些系统尤其可以包括在样品分析之前，期间和/或之后利用发光体（例如纳米晶体）用于校准，验证和/或监测光检测系统的光学参考标准。

8. 发明授权

US07742164B1 Luminescence reference standards 失效
标题翻译：发光参考标准
公开(公告)号：US07742164B1
公开(公告)日：2010-06-22
申请号：US12338778
申请日：2008-12-18
申请人： J. Michael Phillips , Aldrich N. K. Lau , Mark F. Oldham , Kevin S. Bodner , Steven J. Boege , Donald R. Sandell , David H. Tracy
发明人： J. Michael Phillips , Aldrich N. K. Lau , Mark F. Oldham , Kevin S. Bodner , Steven J. Boege , Donald R. Sandell , David H. Tracy
IPC分类号： G01J1/10
CPC分类号： G01N21/278 , B82Y15/00 , G01J1/10 , G01N21/01 , G01N21/4785 , G01N21/6452 , G01N21/76 , G01N2201/06113 , G01N2201/0612 , G01N2201/062 , G01N2201/0691 , G01N2201/0697 , Y10S977/943 , Y10S977/949
摘要： The present teachings provide for systems, and components thereof, for detecting and/or analyzing light. These systems can include, among others, optical reference standards utilizing luminophores, such as nanocrystals, for calibrating, validating, and/or monitoring light-detection systems, before, during, and/or after sample analysis.
摘要翻译：本教导提供了用于检测和/或分析光的系统及其组件。这些系统尤其可以包括在样品分析之前，期间和/或之后利用发光体（例如纳米晶体）用于校准，验证和/或监测光检测系统的光学参考标准。

9. 发明授权

US08641987B2 Sample chamber array and method for processing a biological sample 有权
标题翻译：样品室阵列和处理生物样品的方法
公开(公告)号：US08641987B2
公开(公告)日：2014-02-04
申请号：US10351633
申请日：2003-01-24
申请人： Donald R. Sandell
发明人： Donald R. Sandell
IPC分类号： B01L3/00
CPC分类号： C12Q1/6806 , B01L3/502707 , B01L3/50273 , B01L3/502738 , B01L3/505 , B01L7/52 , B01L2200/0689 , B01L2300/0812 , B01L2300/0816 , B01L2300/0864 , B01L2300/0887 , B01L2400/0406 , B01L2400/0481 , B01L2400/049 , B01L2400/0655 , G01N35/00009 , Y10T156/10
摘要： A sample chamber array is provided. The sample chamber array may comprise at least one reservoir in fluid communication with at least one sample chamber, and a movable portion defining the sample chamber. The reservoir is fillable with a liquid biological sample. The movable portion may be movable with respect to the remainder of the sample chamber from a first position to a second position. In the first position the movable portion is concave and the sample chamber is without biological sample. In the second position the movable portion is convex and the sample chamber comprises biological sample. The movement of the movable portion to the second position causes a pressure drop to transport the biological sample into the sample chamber from the at least one reservoir. Methods for processing a biological sample and methods of making a sample chamber array are also provided.
摘要翻译：提供样品室阵列。样品室阵列可以包括与至少一个样品室流体连通的至少一个储存器和限定样品室的可移动部分。储存器可用液体生物样品填充。可移动部分可以相对于样品室的其余部分从第一位置移动到第二位置。在第一位置，可移动部分是凹的，样品室没有生物样品。在第二位置，可移动部分是凸的，并且样品室包括生物样品。可移动部分到第二位置的运动导致压力下降，以将生物样品从至少一个储存器输送到样品室中。还提供了处理生物样品的方法和制备样品室阵列的方法。

10. 发明授权

US07938570B2 Quick-release worklight mounting 有权
标题翻译：快速安装工作灯
公开(公告)号：US07938570B2
公开(公告)日：2011-05-10
申请号：US10874144
申请日：2004-06-21
申请人： Wade Lee , Donald R. Sandell
发明人： Wade Lee , Donald R. Sandell
IPC分类号： H01R33/00
CPC分类号： F16M11/041 , F16B21/16 , F16M11/08 , F16M11/32 , F21V21/116 , F21W2131/1005
摘要： A quick-release mounting mechanism for a worklight enabling the worklight to be quickly and easily mounted on and demounted from a tripod support stand and enabling an individual worklight head to be quickly and easily mounted on and demounted from a base stand or other support member such as the handle of a spring clamp or other clamp member. The mounting mechanism includes a latch member on the worklight base or on an individual worklight head that cooperates with an actuator mounted in the support stand or other support member. The latch member is received in a hole in the support and the actuator is formed to engage a catch on the latch member when the worklight or individual worklight head is in position on the support. In particular, the actuator is mounted in the support for movement between a latching position and a release position, and the latch member and actuator are formed to engage one another when the actuator is in its latching position so as to hold the worklight or individual worklight head on the support. A spring arrangement in the support urges the actuator into its latching position, and the actuator is provided with an engagement member by which a user can urge the actuator into its release position for quick release of the worklight or the head from the support.
摘要翻译：一种用于工作灯的快速释放安装机构，使得工作灯能够快速且容易地安装在三脚架支撑架上并从三脚架支撑架上卸下，并使单个工作灯头能够快速方便地安装在基座或其他支撑构件上或从基座或其他支撑构件作为弹簧夹或其它夹具的手柄。安装机构包括在工作灯基座上的单独的工作灯头上的闩锁构件，其与安装在支撑架或其他支撑构件中的致动器配合。闩锁构件被容纳在支撑件中的孔中，并且致动器形成为当工作灯或单独的工作灯头在支撑件上就位时接合闩锁构件上的卡扣。特别地，致动器安装在支撑件中以在闩锁位置和释放位置之间移动，并且当致动器处于其闩锁位置时，闩锁构件和致动器形成为彼此接合，以便保持工作灯或单独的工作灯在支持上。支撑件中的弹簧布置促使致动器进入其闩锁位置，并且致动器设置有接合构件，用户可以通过该接合构件将致动器推动到其释放位置，以将工作灯或头部从支撑件快速释放。

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