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    • 7. 发明申请
    • ANALYTE MANIPULATION AND DETECTION
    • 分析操作和检测
    • US20100233675A1
    • 2010-09-16
    • US12438003
    • 2007-08-17
    • Denise BarraultStuart PolwartDavid ThomsonDavid PritchardErling Sundrehagen
    • Denise BarraultStuart PolwartDavid ThomsonDavid PritchardErling Sundrehagen
    • C12Q1/70C07H21/04C07K1/14C12Q1/68C07H21/02C12M1/34
    • G01N33/54313B01L3/502761B01L2200/0647B01L2300/0864B01L2400/0487G01N33/54326G01N33/54333G01N33/56988G01N33/56994
    • Provided is a method for separating two or more analytes in a fluid, which method comprises: (a) binding each different analyte to a different functional particle in one or more binding zones, to produce two or more bound analytes; (b) allowing the bound analytes to move through a separating conduit to two or more separate functional zones; wherein, each different functional particle has, or can be controlled to have, a different function in the fluid as compared with the other functional particles; and wherein the separating conduit separates into two or more functional conduits, such that the separating conduit serves to separate the bound analytes into the separate functional conduits by means of the different functions of the different functional particles. Also provided is an apparatus for separating two or more analytes in a fluid, which apparatus comprises: (a) a binding zone; (b) two or more functional conduits; (c) a separating conduit connecting the binding zone to the two or more functional conduits; (d) a transporter for transporting the analyte through the separating conduit from the binding zone to the two or more functional conduits; and (e) optionally one or more concentrating zones in connection with at least one of the functional conduits.
    • 提供了一种用于分离流体中的两种或更多种分析物的方法,该方法包括:(a)将每种不同的分析物结合到一个或多个结合区域中的不同功能颗粒,以产生两种或更多种结合的分析物; (b)允许结合的分析物通过分离导管移动到两个或更多个分离的功能区; 其中,与其他功能性颗粒相比,每种不同的功能性颗粒具有或可以控制在流体中具有不同的功能; 并且其中所述分离管道分离成两个或更多个功能导管,使得所述分离管道用于通过所述不同功能颗粒的不同功能将结合的分析物分离成分离的功能导管。 还提供了一种用于在流体中分离两种或更多种分析物的装置,该装置包括:(a)结合区; (b)两个或多个功能导管; (c)将结合区域连接到两个或更多个功能导管的分离导管; (d)用于将分析物通过分离导管从结合区输送到两个或更多个功能导管的运送器; 和(e)可选地与至少一个功能导管连接的一个或多个浓缩区。