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1. 发明授权

US5290449A Blood filter material 失效
标题翻译：血液过滤材料
公开(公告)号：US5290449A
公开(公告)日：1994-03-01
申请号：US22642
申请日：1993-02-25
申请人： David G. Heagle , John J. Hiers
发明人： David G. Heagle , John J. Hiers
IPC分类号： A61M1/16 , A61M5/165 , B01D39/08 , B01D39/14 , B01D39/16 , D04H1/54 , D04H1/58 , B01D39/02 , B01D39/04 , B01D39/06
CPC分类号： B01D39/083 , B01D39/163 , D04H1/54 , D04H1/587 , D04H1/64 , A61M2202/0439 , B01D2239/0225 , B01D2239/0407 , B01D2239/0654 , B01D2239/086 , B01D2239/1225 , B01D2239/1233 , B01D2239/1291 , Y10T428/25 , Y10T428/254 , Y10T442/619
摘要： A filter material for filtering leucocytes from a fraction of or whole human blood, comprises a textile web having a thickness of between about 2 millimeters to about 12 millimeters and a bulk density of about 0.05 to 0.4 g/cm.sup.3. The web has a plurality of interlocked textile fibers with average deniers between about 0.05 and 0.75 and average lengths between about 3 millimeters and 15 millimeters. The textile fibers are distributed in the web to form a matrix thereof with spaces between adjacent interstices of interlocked fibers. A plurality of fibrillated particles of textile fiber material, having a surface area of between 5 and 100 square meters per gram are disposed within the spaces of the matrix. The weight ratio of the fibrillated particles to the textile fibers is between about 1:99 and 40:60. A plurality of glass fibers, having an average diameter of between 0.1 and 5 microns and being about 2% to 85% of the web, also form part of the matrix. A thermoplastic binder is disposed at least at cross-over portions of the matrix textile fibers and matrix glass fibers, with the amount of the binder being about 0.1% to 20% by weight of the web.
摘要翻译：用于从一部分或全部人血液中过滤白细胞的过滤材料包括厚度在约2毫米至约12毫米之间且体积密度为约0.05至0.4克/厘米3的织物网。幅材具有多个互锁纺织纤维，平均旦数在约0.05至0.75之间，平均长度在约3毫米至15毫米之间。纺织纤维分布在网状物中以形成其具有在互锁纤维的相邻间隙之间的间隔的基体。纺织纤维材料的多个原纤化颗粒，其表面积为5至100平方米/克，设置在基质的空间内。原纤化颗粒与纺织纤维的重量比为约1:99至40:60。多个玻璃纤维，其平均直径为0.1至5微米，为纤维网的约2％至85％，也形成基体的一部分。至少在基质纺织纤维和基质玻璃纤维的交叉部分处设置热塑性粘合剂，粘合剂的量为纤维网的约0.1重量％至20重量％。

2. 发明授权

US5454946A Filter material for filtering leucocytes from blood 失效
标题翻译：用于从血液中过滤白细胞的过滤材料
公开(公告)号：US5454946A
公开(公告)日：1995-10-03
申请号：US199662
申请日：1994-02-22
申请人： David G. Heagle , John J. Hiers
发明人： David G. Heagle , John J. Hiers
IPC分类号： B01D39/08 , B01D39/16 , D04H1/54 , D04H1/58 , B01D39/02 , B01D39/04 , B01D39/06
CPC分类号： B01D39/083 , B01D39/163 , D04H1/54 , D04H1/587 , D04H1/64 , A61M2202/0439 , B01D2239/0225 , B01D2239/0407 , B01D2239/0654 , B01D2239/086 , B01D2239/1225 , B01D2239/1233 , B01D2239/1291 , Y10T428/25 , Y10T428/254 , Y10T442/699
摘要： A filter material for filtering leucocytes from a fraction of or whole human blood, comprises a web having a thickness of at least about 1 millimeter and a bulk density of about 0.05 to 0.4 g/cm.sup.3. The web has a plurality of interlocked matrix fibers distributed in the web to form a matrix thereof with spaces between adjacent interstices of interlocked fibers. The matrix fibers are composed mainly of about 1 to 3 micron diameter glass fibers, i.e. at least 75% of the weight of the web being the glass fibers. A plurality of fibrillated particles of textile fiber material, having a surface area of between 5 and 100 square meters per gram are disposed within the spaces of the matrix. The weight ratio of the fibrillated particles to the matrix fibers is between about 1:99 and 40:60. A thermoplastic binder is disposed at least at cross-over portions of the matrix fibers, with the amount of the binder being about 0.1% to 10% by weight of the web.
摘要翻译：用于从一部分或全部人血液中过滤白细胞的过滤材料包括具有至少约1毫米厚度和约0.05至0.4g / cm 3的堆积密度的网。纤维网具有分布在纤维网中的多个互锁的基质纤维，以形成具有在互锁纤维的相邻间隙之间的空间的基体。基质纤维主要由约1至3微米直径的玻璃纤维组成，即幅材重量的至少75％是玻璃纤维。纺织纤维材料的多个原纤化颗粒，其表面积为5至100平方米/克，设置在基质的空间内。原纤化颗粒与基质纤维的重量比为约1:99至40:60。至少在基质纤维的交叉部分处设置热塑性粘合剂，粘合剂的量为纤维网的约0.1重量％至10重量％。

3. 发明授权

US5190657A Blood filter and method of filtration 失效
标题翻译：血液过滤器和过滤方法
公开(公告)号：US5190657A
公开(公告)日：1993-03-02
申请号：US733613
申请日：1991-07-22
申请人： David G. Heagle , John J. Hiers
发明人： David G. Heagle , John J. Hiers
IPC分类号： A61M1/16 , A61K35/14 , A61M1/02 , B01D37/00 , B01D39/08 , B01D39/16
CPC分类号： B01D39/083 , B01D39/086 , B01D39/163 , A61M2202/0439 , B01D2239/064 , B01D2239/1225 , B01D2239/1233 , B01D2239/1291 , Y10T428/25 , Y10T428/254 , Y10T442/641 , Y10T442/699
摘要： A filter material for filtering leucocytes from a fraction of or whole human blood, comprises a shape-sustaining laid textile web having a thickness of between about 2 millimeters to about 12 millimeters and a bulk density of about 0.05 to 0.4 g/cm.sup.3. The web has a plurality of interlocked, staple, textile fibers with average deniers between about 0.05 and 0.75 and average lengths between about 3 millimeters and 15 millimeters. The textile fibers are substantially uniformly distributed in the web so as to form a matrix of the textile fibers with spaces between adjacent interstices of interlocked fibers. A plurality of fibrillated particles of a polymeric material, e.g. a textile fiber material, having a surface area of between 5 and 60 square meters per gram are substantially disposed within the spaces of the matrix. The fibrillated particles have a plurality of fine fibrils which are interlocked with adjacent textile fibers of the spaces such that the fibrillated particles are not substantially displaced from the web during filtration of the blood. The weight ratio of the fibrillated particles to the textile fibers is between about 1:99 and 40:60.
摘要翻译：用于从一部分或全部人血液中过滤白细胞的过滤材料包括具有约2毫米至约12毫米厚度和约0.05至0.4克/厘米3的堆积密度的形状维持铺设的织物网。纤维网具有多个互锁的缝合纤维，平均旦数在约0.05至0.75之间，平均长度在约3毫米至15毫米之间。纺织纤维基本上均匀地分布在纤维网中，以便形成纺织纤维的基质，在互锁纤维的相邻间隙之间具有空隙。多个原纤化的聚合物材料颗粒，例如聚合物材料。表面积为5至60平方米/克的织物纤维材料基本上设置在基质的空间内。原纤化颗粒具有多个细纤维，其与空间的相邻织物纤维互锁，使得在过滤血液期间原纤化颗粒基本上不从纸幅移位。原纤化颗粒与纺织纤维的重量比为约1:99至40:60。

4. 发明授权

US07799965B2 Wound dressings with anti-microbial and zinc-containing agents 有权
标题翻译：伤口敷料用抗微生物剂和含锌剂
公开(公告)号：US07799965B2
公开(公告)日：2010-09-21
申请号：US11783668
申请日：2007-04-11
申请人： Harish A. Patel , Hansen P. Swaniker , David G. Heagle , Kate Ward , Alain Tranchemontagne , E. David Fink , Ronald F. Vitaris , Chirag B. Shah , Sharon A. Mulligan , Brian Dowd , Scott Orr
发明人： Harish A. Patel , Hansen P. Swaniker , David G. Heagle , Kate Ward , Alain Tranchemontagne , E. David Fink , Ronald F. Vitaris , Chirag B. Shah , Sharon A. Mulligan , Brian Dowd , Scott Orr
IPC分类号： A61F13/00 , A61L15/16
CPC分类号： A61L15/44 , A61F13/00029 , A61F13/00063 , A61F2013/00463 , A61F2013/00727 , A61F2013/0091 , A61L15/18 , A61L15/46 , A61L2300/102 , A61L2300/104 , A61L2300/206 , A61L2300/404 , A61L2300/61
摘要： A wound dressing includes one or more layers containing a first anti-microbial agent and/or at least one zinc-containing agent.
摘要翻译：伤口敷料包括含有第一抗微生物剂和/或至少一种含锌剂的一层或多层。

5. 发明申请

US20100191196A1 Fibrous Wound Filler Material for Negative Pressure Wound Therapy 审中-公开
标题翻译：用于负压伤口治疗的纤维缠绕填充材料
公开(公告)号：US20100191196A1
公开(公告)日：2010-07-29
申请号：US12359718
申请日：2009-01-26
申请人： David G. Heagle
发明人： David G. Heagle
IPC分类号： A61F13/00 , A61M1/00 , B32B37/00
CPC分类号： A61F13/00995 , A61F13/00068 , A61F13/0203 , A61M1/0088 , B29C65/086 , B29C65/7437 , B29C65/7443 , B29C66/1122 , B29C66/21 , B29C66/232 , B29C66/43 , B29C66/71 , B29C66/7294 , B29C66/73921 , B29C66/81433 , B29C66/83411 , B29K2023/06 , B29K2023/12 , B29K2027/12 , B29K2027/18 , B29K2067/00 , B29K2077/00 , B29K2083/00 , B29K2105/0854 , B29K2423/00 , B29L2031/753 , B32B37/00 , B32B38/04 , B32B2305/10 , B32B2305/20 , B32B2309/10 , B32B2535/00 , D04H3/14 , B29K2067/003 , B29K2023/00
摘要： An apparatus for promoting the healing of an exuding wound includes a wound cover for defining a reservoir over a wound in which a negative pressure may be maintained. The cover may form a substantially fluid-tight seal around the wound and permit fluid communication between the reservoir and a vacuum source suitable for providing an appropriate negative pressure to the reservoir to stimulate healing of the wound. A wound filler positioned between the wound and the wound cover includes a nonwoven material at least partially perforated by sonic welding.
摘要翻译：用于促进渗出伤口愈合的装置包括用于在可以维持负压的伤口上限定储存器的伤口盖。盖可围绕伤口形成基本上流体密封的密封，并允许储存器和真空源之间的流体连通，适合于向贮存器提供适当的负压以刺激伤口的愈合。定位在伤口和伤口盖之间的伤口填充物包括至少部分通过声波焊接穿孔的非织造材料。

6. 发明申请

US20100185163A1 Method and Apparatus for Bridging From a Dressing in Negative Pressure Wound Therapy 有权
标题翻译：从负压伤口治疗敷料中桥接的方法和装置
公开(公告)号：US20100185163A1
公开(公告)日：2010-07-22
申请号：US12356246
申请日：2009-01-20
申请人： David G. Heagle
发明人： David G. Heagle
IPC分类号： A61M1/00
CPC分类号： A61M1/0088 , A61F13/00068 , A61F13/0203 , A61F2013/00174 , A61F2013/00412 , A61F2013/00536 , A61F2013/0054 , A61F2013/00553 , A61M1/0086 , A61M27/00
摘要： A method of bridging from a wound dressing to a wound port for negative pressure wound therapy includes positioning an elongate wick between a wound and a remote location with respect to the wound. The elongate wick includes a three-dimensional spacer fabric having an upper fabric layer spaced from a lower fabric layer by an intermediate layer of pile threads. The elongate wick is covered with a flexible wick cover such that an enclosure is formed around the elongate wick. A substantially fluid-tight seal is established between a first end of the elongate wick cover and the wound dressing such that a reservoir is defined over the wound in which a negative pressure may be maintained. A substantially fluid-tight seal is established between a second end of the elongate wick cover and a fluid port configured for connection to a source of negative pressure.
摘要翻译：从伤口敷料桥接到用于负压伤口治疗的伤口的方法包括将细长的芯线相对于伤口定位在伤口和远程位置之间。细长芯包括三维间隔织物，其具有通过中间层绒线与下织物层隔开的上织物层。细长的灯芯覆盖有柔性灯芯盖，使得围绕细长灯芯形成外壳。在细长的吸油芯盖的第一端和伤口敷料之间建立基本上流体密封的密封，使得储存器被限定在可以保持负压的伤口上。在细长的灯芯盖的第二端和被配置为连接到负压源的流体端口之间建立基本上流体密封的密封。

7. 发明申请

US20100036334A1 Wound Dressing of Continuous Fibers 审中-公开
标题翻译：连续纤维的伤口敷料
公开(公告)号：US20100036334A1
公开(公告)日：2010-02-11
申请号：US12537284
申请日：2009-08-07
申请人： David G. Heagle , Kevin Corley , Kristin L. Watson
发明人： David G. Heagle , Kevin Corley , Kristin L. Watson
IPC分类号： A61F13/15 , A61M1/00
CPC分类号： A61F13/00068 , A61F13/00042 , A61F13/00063 , A61F13/00995 , A61F13/02 , A61F13/0216 , A61F2013/00174 , A61F2013/00238 , A61F2013/00348 , A61F2013/00357 , A61F2013/00412 , A61F2013/00519 , A61F2013/00536 , A61F2013/0054 , A61F2013/00557 , A61F2013/00565 , A61F2013/0057 , A61F2013/00842 , A61M1/0023 , A61M1/0088
摘要： A method for treating a wound that includes incorporating a wound dressing comprising a plurality of fibers, each fiber having a length of at least two (2) inches, into a wound to cause the walls of the wound to remain apart and allow the wound to heal from the inside to the outside, and removing the wound exudate.
摘要翻译：一种用于治疗伤口的方法，其包括将包含多根纤维的伤口敷料（每种纤维具有至少两（2）英寸的长度）并入伤口中，以使伤口的壁保持分开并使伤口从内到外愈合，并清除伤口渗出物。

8. 发明申请

US20130172834A1 Fibrous Wound Filler Material for Negative Pressure Wound Therapy 审中-公开
标题翻译：用于负压伤口治疗的纤维缠绕填充材料
公开(公告)号：US20130172834A1
公开(公告)日：2013-07-04
申请号：US13551963
申请日：2012-07-18
申请人： David G. Heagle
发明人： David G. Heagle
IPC分类号： A61F13/00
CPC分类号： A61F13/00995 , A61F13/00068 , A61F13/0203 , A61M1/0088 , B29C65/086 , B29C65/7437 , B29C65/7443 , B29C66/1122 , B29C66/21 , B29C66/232 , B29C66/43 , B29C66/71 , B29C66/7294 , B29C66/73921 , B29C66/81433 , B29C66/83411 , B29K2023/06 , B29K2023/12 , B29K2027/12 , B29K2027/18 , B29K2067/00 , B29K2077/00 , B29K2083/00 , B29K2105/0854 , B29K2423/00 , B29L2031/753 , B32B37/00 , B32B38/04 , B32B2305/10 , B32B2305/20 , B32B2309/10 , B32B2535/00 , D04H3/14 , B29K2067/003 , B29K2023/00
摘要： An apparatus for promoting the healing of an exuding wound includes a wound cover for defining a reservoir over a wound in which a negative pressure may be maintained. The cover may form a substantially fluid-tight seal around the wound and permit fluid communication between the reservoir and a vacuum source suitable for providing an appropriate negative pressure to the reservoir to stimulate healing of the wound. A wound filler positioned between the wound and the wound cover includes a nonwoven material at least partially perforated by sonic welding.
摘要翻译：用于促进渗出伤口愈合的装置包括用于在可以维持负压的伤口上限定储存器的伤口盖。盖可围绕伤口形成基本上流体密封的密封，并允许储存器和真空源之间的流体连通，适合于向贮存器提供适当的负压以刺激伤口的愈合。定位在伤口和伤口盖之间的伤口填充物包括至少部分通过声波焊接穿孔的非织造材料。

9. 发明授权

US08162907B2 Method and apparatus for bridging from a dressing in negative pressure wound therapy 有权
标题翻译：用于从负压伤口治疗中的敷料桥接的方法和装置
公开(公告)号：US08162907B2
公开(公告)日：2012-04-24
申请号：US12356246
申请日：2009-01-20
申请人： David G. Heagle
发明人： David G. Heagle
IPC分类号： A61M1/00
CPC分类号： A61M1/0088 , A61F13/00068 , A61F13/0203 , A61F2013/00174 , A61F2013/00412 , A61F2013/00536 , A61F2013/0054 , A61F2013/00553 , A61M1/0086 , A61M27/00
摘要： A method of bridging from a wound dressing to a wound port for negative pressure wound therapy includes positioning an elongate wick between a wound and a remote location with respect to the wound. The elongate wick includes a three-dimensional spacer fabric having an upper fabric layer spaced from a lower fabric layer by an intermediate layer of pile threads. The elongate wick is covered with a flexible wick cover such that an enclosure is formed around the elongate wick. A substantially fluid-tight seal is established between a first end of the elongate wick cover and the wound dressing such that a reservoir is defined over the wound in which a negative pressure may be maintained. A substantially fluid-tight seal is established between a second end of the elongate wick cover and a fluid port configured for connection to a source of negative pressure.
摘要翻译：从伤口敷料桥接到用于负压伤口治疗的伤口的方法包括将细长的芯线相对于伤口定位在伤口和远程位置之间。细长芯包括三维间隔织物，其具有通过中间层绒线与下织物层隔开的上织物层。细长的灯芯覆盖有柔性灯芯盖，使得围绕细长灯芯形成外壳。在细长的吸油芯盖的第一端和伤口敷料之间建立基本上流体密封的密封，使得储存器被限定在可以保持负压的伤口上。在细长的灯芯盖的第二端和被配置为连接到负压源的流体端口之间建立基本上流体密封的密封。

10. 发明授权

US07750201B2 Wound dressings with anti-microbial and chelating agents 有权
标题翻译：伤口敷料用抗微生物剂和螯合剂
公开(公告)号：US07750201B2
公开(公告)日：2010-07-06
申请号：US11783667
申请日：2007-04-11
申请人： Harish A. Patel , Hansen P. Swaniker , David G. Heagle , Kate Ward , Alain Tranchemontagne , E. David Fink , Ronald F. Vitaris , Chirag B. Shah , Sharon A. Mulligan , Brian Dowd , Scott Orr
发明人： Harish A. Patel , Hansen P. Swaniker , David G. Heagle , Kate Ward , Alain Tranchemontagne , E. David Fink , Ronald F. Vitaris , Chirag B. Shah , Sharon A. Mulligan , Brian Dowd , Scott Orr
IPC分类号： A61F13/00 , A61L15/16
CPC分类号： A61L15/46 , A61F13/00029 , A61F13/00063 , A61F2013/00463 , A61F2013/00472 , A61F2013/00608 , A61F2013/0091 , A61F2013/00927 , A61F2013/00936 , A61L15/18 , A61L15/20 , A61L2300/102 , A61L2300/206 , A61L2300/404 , A61L2300/61
摘要： A wound dressing includes one or more layers containing a first anti-microbial agent and at least one of: a chelating agent, and a second anti-microbial agent.
摘要翻译：伤口敷料包括含有第一抗微生物剂和至少一种螯合剂和第二抗微生物剂的一层或多层。

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