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1. 发明授权

US5407424A Angioplasty perfusion pump 失效
标题翻译：血管成形术灌注泵
公开(公告)号：US5407424A
公开(公告)日：1995-04-18
申请号：US22048
申请日：1993-02-24
申请人： Daniel M. LaFontaine , Thomas J. Holman , Daniel O. Adams
发明人： Daniel M. LaFontaine , Thomas J. Holman , Daniel O. Adams
IPC分类号： A61M1/00 , A61M1/36 , A61M37/00
CPC分类号： A61M1/0005 , A61M1/3613 , A61M1/0062
摘要： A double acting piston blood pump having distal and proximal manifolds that are connected by a cylinder having a piston reciprocating therein and dividing the cylinder into a proximal and distal chambers. The manifolds have chambers that are in fluid communication with the distal and proximal chambers of the cylinder and one way valves for controlling fluid flow from and to the cylinder chambers.
摘要翻译：具有远端和近端歧管的双作用活塞血泵，其通过具有往复运动的活塞的气缸连接并将气缸分成近端和远端腔室。歧管具有与气缸的远端和近端腔室流体连通的腔室，以及用于控制流体流向气缸室的单向阀。

2. 发明授权

US5554119A Drug delivery catheter with manifold 失效
标题翻译：药物输送导管与歧管
公开(公告)号：US5554119A
公开(公告)日：1996-09-10
申请号：US187614
申请日：1994-01-27
申请人： Kent D. Harrison , Gary L. Hendrickson , Thomas J. Holman , Daniel M. Lafontaine , Matthew J. Miller , David B. Robinson
发明人： Kent D. Harrison , Gary L. Hendrickson , Thomas J. Holman , Daniel M. Lafontaine , Matthew J. Miller , David B. Robinson
IPC分类号： A61M25/00 , A61F2/958 , A61M16/04 , A61M29/02 , A61M5/32
CPC分类号： A61M25/1002 , A61M16/0481 , A61M2025/105 , A61M2025/1052 , A61M2025/1072 , A61M2025/1097
摘要： A drug delivery catheter which may be inserted into a vessel, such as a blood vessel is disclosed. The drug delivery catheter comprises any elongated tubular member which has a proximal end and a distal end. A drug lumen which provides a communication path for fluid is provided in the elongated tubular member for delivering a fluid, such as the drug to be administered. An inflatable balloon assembly is provided at the distal end of the elongated tubular member. The balloon assembly includes apertures which communicate with the drug lumen. The balloon assembly comprises a tubular balloon which is helically wound through the elongated tubular member and a sheath. The sheath is attached to the helically wound tubular balloon such that when the balloon member is uninflated, the first fluid in the vessel flows around the balloon assembly and such that when the balloon member is inflated, sections of the helically wound balloon contact the vessel wall to form a containment pocket between the vessel wall, the contacting sections of the balloon and the sheath. The apertures are provided in the containment pocket. An inflatable lumen is defined through the interior of the helically wound balloon and the sheath to allow perfusion of the first fluid.
摘要翻译：公开了一种可插入容器（如血管）中的药物输送导管。药物递送导管包括具有近端和远端的任何细长管状构件。提供用于流体的连通路径的药物腔室设置在细长管状构件中，用于输送流体，例如待施用的药物。在细长管状构件的远端处设置可充气气囊组件。气囊组件包括与药物腔连通的孔。球囊组件包括通过细长管状构件和护套螺旋缠绕的管状球囊。护套附接到螺旋形缠绕的管状气囊，使得当球囊构件未膨胀时，容器中的第一流体围绕球囊组件流动，使得当球囊构件膨胀时，螺旋形卷绕的球囊的部分接触血管壁以在容器壁，球囊和护套的接触部分之间形成容纳袋。孔口设置在容纳口袋中。通过螺旋缠绕气囊和护套的内部限定可充气腔，以允许第一流体的灌注。

3. 发明授权

US5318533A Balloon catheter inflation device including apparatus for monitoring and wireless transmission of inflation data, and system 失效
标题翻译：球囊导管充气装置，包括用于监测和无线传输通气数据的装置，以及系统
公开(公告)号：US5318533A
公开(公告)日：1994-06-07
申请号：US839628
申请日：1992-02-21
申请人： Daniel O. Adams , David J. Haskvitz , Thomas J. Holman , William H. Penny , David J. Serdar , John M. Yates
发明人： Daniel O. Adams , David J. Haskvitz , Thomas J. Holman , William H. Penny , David J. Serdar , John M. Yates
IPC分类号： A61F2/958 , A61M29/00 , A61M5/00
CPC分类号： A61M25/10184 , A61M25/1018 , A61M25/10182 , A61M25/104 , A61M2205/50 , Y10S128/903
摘要： An inflation device includes a syringe forming a cylindrical chamber containing a plunger carrying a stopper or piston arrangement. The chamber is designed to contain an inflation fluid and is in fluid communication with the lumen of a balloon catheter. Movement of the plunger within the chamber will increase or decrease the pressure of the fluid within the chamber and lumen, thereby inflating or deflating the balloon at the distal end of the catheter. A pressure sensor is mounted to the housing in fluid communication with the lumen and is electrically connected to a battery-operated transmitter. The transmitter broadcasts signals representing pressure within the lumen and balloon to a remote receiver. The receiver includes a microprocessor containing a clock and operable to display time and pressure data. A flexible insulator strip is interposed between the battery and the transmitter circuit to prevent operation of the transmitter until desired by the cardiologist. The housing of the inflation device may be opened to remove the batteries for separate disposal and to render the circuit inoperative to prevent reuse. A look-up table associated with the microprocessor permits display of balloon diameter during the procedure.
摘要翻译：膨胀装置包括一个注射器，该注射器形成一个圆筒形腔室，该圆柱形腔室包含一个承载塞子或腔室被设计成容纳充气流体并且与球囊导管的内腔流体连通。柱塞在腔室内的运动将增加或减小腔室和腔内的流体的压力，从而在导管的远端处膨胀或放气气囊。压力传感器安装到外壳上，与腔体流体连通，并与电池供电的变送器电连接。发射机将表示内腔和气球内的压力的信号广播到远程接收器。接收机包括一个包含时钟并可操作以显示时间和压力数据的微处理器。在电池和发射器电路之间插入柔性绝缘体条，以防止发射器的操作，直到心脏病专家期望。可以打开充气装置的壳体以移除电池以进行单独处理，并使电路不起作用以防再次使用。与微处理器相关联的查找表允许在该过程期间显示气球直径。

4. 发明授权

US08795348B2 Medical devices and related methods 有权
标题翻译：医疗器械及相关方法
公开(公告)号：US08795348B2
公开(公告)日：2014-08-05
申请号：US11152555
申请日：2005-06-14
申请人： Jan Weber , Thomas J. Holman , Scott Schewe
发明人： Jan Weber , Thomas J. Holman , Scott Schewe
IPC分类号： A61F2/06 , A61M29/00
CPC分类号： A61F2/95 , A61F2/91 , A61F2/958 , A61F2210/0033 , A61F2220/005 , A61F2220/0058 , A61F2250/0018 , A61F2250/0068 , A61M25/09 , A61M25/1006 , A61M25/10186 , A61M2025/1015 , A61M2025/105 , A61M2025/1056 , A61M2025/1068 , A61M2025/1086 , A61M2025/1093
摘要： A medical system including an elongate member and an elongate element associated with the elongate member so that a shape of the elongate member can be altered upon applying energy to the element.
摘要翻译：一种医疗系统，包括细长构件和与细长构件相关联的细长元件，使得在向元件施加能量时可以改变细长构件的形状。

5. 发明申请

US20120197380A1 Medical Devices and Related Methods 有权
标题翻译：医疗器械及相关方法
公开(公告)号：US20120197380A1
公开(公告)日：2012-08-02
申请号：US13441664
申请日：2012-04-06
申请人： Thomas J. Holman , James Lee Shippy, III , Afsar Ali
发明人： Thomas J. Holman , James Lee Shippy, III , Afsar Ali
IPC分类号： A61F2/84 , A61L29/16 , A61M25/10
CPC分类号： A61M25/1002 , A61F2/958 , A61L29/16 , A61M25/1038 , A61M2025/1004 , A61M2025/1031 , A61M2025/1088
摘要： This disclosure relates to medical devices and related methods. In some embodiments, the methods include applying a material to the balloon and then removing the material from one or more regions of the balloon.
摘要翻译：本公开涉及医疗装置和相关方法。在一些实施例中，所述方法包括将材料施加到球囊，然后从气囊的一个或多个区域移除材料。

6. 发明申请

US20110054394A1 BONDING SLEEVE FOR A MEDICAL DEVICE 有权
标题翻译：用于医疗设备的连接套管
公开(公告)号：US20110054394A1
公开(公告)日：2011-03-03
申请号：US12872882
申请日：2010-08-31
申请人： Matthew C. Heidner , Thomas J. Holman
发明人： Matthew C. Heidner , Thomas J. Holman
IPC分类号： A61M29/00 , B29C65/02
CPC分类号： A61F2/958 , A61F2002/9583
摘要： A medical device delivery system comprises an inner tube, a medical device disposed about a portion of the distal region of the inner tube, a medical device sheath disposed about the medical device, a medical device sheath retraction device extending proximally from the medical device sheath and an outer sheath disposed about a portion of the medical device sheath retraction device. The distal end of the outer sheath terminates at least one medical device length proximal of the medical device. The medical device sheath is movable relative to the outer sheath and relative to the inner tube.
摘要翻译：医疗装置输送系统包括内管，围绕内管的远端区域的一部分设置的医疗装置，围绕医疗装置设置的医疗装置护套，从医疗装置护套向近侧延伸的医疗装置护套收回装置，设置在所述医疗装置鞘缩回装置的一部分周围的外护套。外护套的远端终止医疗装置近端的至少一个医疗装置长度。医疗器械护套可相对于外护套和相对于内管移动。

7. 发明授权

US07691082B2 Medical devices 有权
标题翻译：医疗设备
公开(公告)号：US07691082B2
公开(公告)日：2010-04-06
申请号：US11174258
申请日：2005-07-01
申请人： James Lee Shippy, III , Thomas J. Holman
发明人： James Lee Shippy, III , Thomas J. Holman
IPC分类号： A61M31/00
CPC分类号： A61M25/1002 , A61M25/1029 , A61M25/1038 , A61M2025/1004 , A61M2025/1031 , A61M2025/1075 , A61M2025/1086 , Y10T428/139
摘要： Medical devices, for example, those that have balloons, and methods of making the devices are described. For example, in some embodiments, a medical device includes an elongated shaft, and an inflatable balloon carried by the shaft. The balloon includes a first recessed channel, a second recessed channel, a third recessed channel, and a fourth recessed channel, wherein the first recessed channel is spaced from the second recessed channel by a first distance, the third recessed channel is spaced from the fourth recessed channel by the first distance, and the second recessed channel is spaced from the third recessed channel by a second distance different than the first distance.
摘要翻译：描述了医疗设备，例如具有气球的设备，以及制造设备的方法。例如，在一些实施例中，医疗装置包括细长轴和由轴承载的可膨胀气囊。气球包括第一凹槽，第二凹槽，第三凹槽和第四凹槽，其中第一凹槽与第二凹槽相隔第一距离，第三凹槽与第四凹槽相隔，并且所述第二凹陷通道与所述第三凹陷通道间隔不同于所述第一距离的第二距离。

8. 发明申请

US20090125786A1 Mechanism for Adjacent-Symbol Error Correction and Detection 有权
标题翻译：相邻符号误差校正和检测机制
公开(公告)号：US20090125786A1
公开(公告)日：2009-05-14
申请号：US12354037
申请日：2009-01-15
申请人： James W. Alexander , Thomas J. Holman , Mark A. Heap , Stanley S. Kulick
发明人： James W. Alexander , Thomas J. Holman , Mark A. Heap , Stanley S. Kulick
IPC分类号： G11C29/04 , G06F11/07 , G06F11/22
CPC分类号： G11C29/42 , G11C11/401 , G11C2029/0409
摘要： According to one embodiment a computer system is disclosed. The computer system includes memory. The memory includes two or more rows, where each row has a plurality of memory devices. The computer system also includes a chipset. The chipset includes a detection/correction circuit to detect single and double symbol errors and correct single symbol errors for each memory row, and markers to maintain a log of errors within each memory row.
摘要翻译：根据一个实施例，公开了一种计算机系统。计算机系统包括内存。存储器包括两行或更多行，其中每行具有多个存储器件。计算机系统还包括芯片组。该芯片组包括一个检测/校正电路，用于检测单个和双重符号错误，并纠正每个存储器行的单个符号错误，以及标记以维护每个存储器行内的错误日志。

9. 发明授权

US07491188B2 Reinforced and drug-eluting balloon catheters and methods for making same 有权
标题翻译：加强和药物洗脱球囊导管及其制作方法
公开(公告)号：US07491188B2
公开(公告)日：2009-02-17
申请号：US10963272
申请日：2004-10-12
申请人： Thomas J. Holman , Jan Weber , Scott Schewe
发明人： Thomas J. Holman , Jan Weber , Scott Schewe
IPC分类号： A61M29/00
CPC分类号： A61M25/1029 , A61M25/10 , A61M25/1002 , A61M25/1034 , A61M25/1038 , A61M2025/0058 , A61M2025/1031 , A61M2025/105 , A61M2025/1084
摘要： The present invention generally relates to the field of intravascular medical devices, and more specifically to the field of balloon catheters and other similar diagnostic or therapeutic catheters within the body for treatment and diagnosis of diseases. In particular, the present invention relates to reinforced balloon catheters and drug-eluting balloon catheters and corresponding methods for producing same.
摘要翻译：本发明一般涉及血管内医疗装置的领域，更具体地涉及用于治疗和诊断疾病的体内气囊导管和其它类似的诊断或治疗导管领域。特别地，本发明涉及增强气囊导管和药物洗脱球囊导管及其相应的制造方法。

10. 发明申请

US20080114331A1 Medical devices and related methods 有权
标题翻译：医疗器械及相关方法
公开(公告)号：US20080114331A1
公开(公告)日：2008-05-15
申请号：US11599052
申请日：2006-11-14
申请人： Thomas J. Holman , James Lee Shippy , Afsar Ali
发明人： Thomas J. Holman , James Lee Shippy , Afsar Ali
IPC分类号： A61M25/10
CPC分类号： A61M25/1002 , A61F2/958 , A61L29/16 , A61M25/1038 , A61M2025/1004 , A61M2025/1031 , A61M2025/1088
摘要： This disclosure relates to medical devices and related methods. In some embodiments, the methods include applying a material to the balloon and then removing the material from one or more regions of the balloon.
摘要翻译：本公开涉及医疗装置和相关方法。在一些实施例中，所述方法包括将材料施加到球囊，然后从气囊的一个或多个区域移除材料。

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