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1. 发明公开

US20240173151A1 DEVICES AND METHODS FOR CORONARY SINUS PRESSURE RELIEF 审中-公开
公开(公告)号：US20240173151A1
公开(公告)日：2024-05-30
申请号：US18450284
申请日：2023-08-15
申请人： Corvia Medical, Inc.
发明人： Edward I. MCNAMARA
IPC分类号： A61F2/844 , A61B17/00 , A61B17/22 , A61B17/221 , A61B18/00 , A61B18/14 , A61F2/06 , A61F2/24 , A61F2/82 , A61F2/90 , A61F2/91 , A61F2/954 , A61L31/02 , A61M1/36 , A61M29/02
CPC分类号： A61F2/844 , A61B17/0057 , A61F2/2493 , A61F2/90 , A61B2017/00247 , A61B2017/00252 , A61B2017/00575 , A61B2017/00592 , A61B2017/00597 , A61B2017/00606 , A61B2017/00623 , A61B2017/22035 , A61B17/221 , A61B2017/2215 , A61B2018/00023 , A61B2018/00351 , A61B2018/144 , A61B18/1492 , A61F2002/061 , A61F2/2403 , A61F2/2412 , A61F2/2418 , A61F2/2451 , A61F2/2478 , A61F2/82 , A61F2002/821 , A61F2/91 , A61F2/954 , A61F2210/0014 , A61F2220/0008 , A61F2220/0041 , A61F2220/005 , A61F2220/0058 , A61F2230/0017 , A61F2230/005 , A61F2230/0054 , A61F2230/0067 , A61F2250/0067 , A61F2250/0069 , A61F2250/0098 , A61L31/022 , A61M1/3613 , A61M29/02
摘要： A method and devices for relieving pressure in the left atrium of a patient's heart is disclosed. The method includes using an ablative catheter in a minimally invasive procedure to prepare an opening from the coronary sinus into a left atrium of the patient's heart. Once the opening is prepared, the opening may be enlarged by a technique such as expanding a balloon within the opening. A stent is then placed within the coronary sinus of the patient, with a transverse portion expanding within the opening, allowing blood to flow from the left atrium to the coronary sinus and then to the right atrium. Pressure within the left atrium is thus relieved.

2. 发明公开

US20240148948A1 LOCO-REGIONAL PERFUSION OF AN UNARRESTED BEATING HEART 审中-公开
公开(公告)号：US20240148948A1
公开(公告)日：2024-05-09
申请号：US18277959
申请日：2022-02-22
申请人： DiNAQOR AG
发明人： Johannes HOLZMEISTER , Valeria RICOTTI , Mark DEHDASHTIAN
IPC分类号： A61M1/36 , A61M1/00
CPC分类号： A61M1/3613 , A61M1/3601 , A61M1/3659 , A61M1/3666 , A61M1/71 , A61M2202/0007 , A61M2202/0413 , A61M2205/3334
摘要： Disclosed is a method for treating a heart condition by perfusing a drug through an un-arrested beating heart of a patient. A closed circuit through the patient's coronary arteries and coronary venous system may be formed from a first drug delivery catheter (1822) positioned in the right coronary artery, a second drug delivery catheter (1824) positioned in the left coronary artery, a drug recovery catheter (1826) positioned in a coronary sinus, and an external membrane oxygenation system (1820) fluidly coupled to the various catheters. A drug for treating a heart condition may be perfused through the closed circuit.

3. 发明授权

US11738131B2 Expandable ECMO extension cannula system 有权
公开(公告)号：US11738131B2
公开(公告)日：2023-08-29
申请号：US18151982
申请日：2023-01-09
申请人： Tufts Medical Center, Inc.
发明人： Navin K. Kapur
IPC分类号： A61M1/36 , A61M25/00
CPC分类号： A61M1/3613 , A61M1/3659 , A61M2025/0024 , A61M2210/127
摘要： An extension cannula for use with a conventional ECMO return cannula is provided. The extension cannula includes a flexible conduit transitionable between a collapsed insertion state and an expanded deployed state when in communication with blood flow from an ECMO machine via the ECMO return cannula. The extension cannula may be positioned through a conventional ECMO return cannula such that the proximal end of the flexible conduit is disposed within and proximal to the end of the ECMO return cannula, while the distal end of the flexible conduit is disposed in a patient's thoracic aorta to deliver oxygenated blood directly to the patient's thoracic aorta via one or more pores at the distal region of the flexible conduit to improve cerebral oxygenation, maintain systemic arterial pulsatility, and reduce the potential for end-organ injury.

4. 发明申请

US20170354523A1 Systems And Methods For Treating A Carotid Artery 审中-公开
公开(公告)号：US20170354523A1
公开(公告)日：2017-12-14
申请号：US15601587
申请日：2017-05-22
申请人： Silk Road Medical, Inc.
发明人： Tony M. Chou , Michi E. Garrison , Gregory M. Hyde , Richard Renati , Alan Schaer
IPC分类号： A61F2/954 , A61M1/36 , A61F2/95 , A61F2/915 , A61B17/04 , A61B17/02 , A61B17/00 , A61F2/844 , A61B17/3207 , A61M27/00 , A61M25/10 , A61B17/34 , A61M25/04 , A61F2/01 , A61F2/856 , A61B17/22 , A61F2/06 , A61F2/90 , A61M25/06
CPC分类号： A61F2/954 , A61B17/0057 , A61B17/0218 , A61B17/0469 , A61B17/3207 , A61B2017/0065 , A61B2017/00663 , A61B2017/00668 , A61B2017/00778 , A61B2017/00986 , A61B2017/0472 , A61B2017/22047 , A61B2017/320716 , A61B2017/3482 , A61B2017/3484 , A61F2/013 , A61F2/844 , A61F2/856 , A61F2/90 , A61F2/915 , A61F2/95 , A61F2002/011 , A61F2002/065 , A61F2002/067 , A61F2002/9511 , A61F2002/9517 , A61F2250/0037 , A61M1/3613 , A61M1/3659 , A61M25/04 , A61M25/10 , A61M25/104 , A61M27/00 , A61M27/002 , A61M2025/0681 , A61M2025/1052
摘要： Systems and methods are adapted for treating the carotid artery. The systems include interventional catheters and blood vessel access devices that are adapted for transcervical insertion into the carotid artery. Embodiments of the systems and methods can be used in combination with embolic protection systems including blood flow reversal mechanisms, arterial filters, and arterial occlusion devices.

5. 发明授权

US09504779B2 Method and apparatus for mitigating acute reoxygenation injury during percutaneous coronary intervention 有权
公开(公告)号：US09504779B2
公开(公告)日：2016-11-29
申请号：US14802340
申请日：2015-07-17
申请人： Rheoxtech, LLC
发明人： Neil J. Thomas , Gintaras A. Vaisnys
IPC分类号： A61M31/00 , A61M1/32 , A61M25/10 , A61M1/36 , A61M5/172
CPC分类号： A61M1/3613 , A61M1/1698 , A61M1/32 , A61M1/36 , A61M1/3664 , A61M1/3666 , A61M5/1723 , A61M25/10 , A61M25/104 , A61M2025/1095 , A61M2202/0439 , A61M2205/3306 , A61M2205/3375 , A61M2230/005 , A61M2230/205
摘要： A system and methods are described for improving the management of ischemic cardiac tissue during acute coronary syndromes. The system combines a catheter-based sub-system which allows for simultaneous balloon dilation of a coronary artery and infusion of a carefully controlled perfusate during percutaneous coronary intervention. The system allows for modulation of levels of oxygen at the time of percutaneous intervention. In addition, catheters and systems are provided for administration of fluids with modified oxygen content during an intervention that incorporate upstream flow control members to compartmentalize the perfusion of the target coronary artery and the remainder of the heart.

6. 发明申请

US20160263356A1 Cardiopulmonary Resuscitation Catheter and Related Systems and Methods 审中-公开
标题翻译：心肺复苏导管及相关系统及方法
公开(公告)号：US20160263356A1
公开(公告)日：2016-09-15
申请号：US15066819
申请日：2016-03-10
申请人： Regents of the University of Minnesota
发明人： Ahmed Selim
IPC分类号： A61M25/10 , A61M5/142 , A61M25/00
CPC分类号： A61M25/1011 , A61M1/1698 , A61M1/3613 , A61M1/3666 , A61M1/3667 , A61M2025/1052 , A61M2039/082
摘要： The disclosed device, systems and methods relate to a novel catheter, system and methods. The various catheter implementations are for use in cardiopulmonary resuscitation and other medical or surgical conditions that require emergency restoration of cerebral and cardiac blood supply. The catheter or catheters have one or more lumens and balloons. Two catheters connected to a control unit can be disposed within the body to occlude and perfuse a region of the circulatory system.
摘要翻译：所公开的装置，系统和方法涉及新颖的导管，系统和方法。各种导管实施用于心肺复苏术和需要紧急恢复脑血供和心脏血液供应的其他医疗或手术病症。导管或导管具有一个或多个流明和气球。连接到控制单元的两个导管可以设置在体内以封闭和灌注循环系统的区域。

7. 发明授权

US09132010B2 Devices and methods for controlling blood perfusion pressure 有权
标题翻译：用于控制血液灌注压力的装置和方法
公开(公告)号：US09132010B2
公开(公告)日：2015-09-15
申请号：US13562602
申请日：2012-07-31
申请人： Ghassan S. Kassab , Jose A. Navia, Sr.
发明人： Ghassan S. Kassab , Jose A. Navia, Sr.
IPC分类号： A61M29/00 , A61F2/24 , A61F2/07 , A61M1/36
CPC分类号： A61F2/2493 , A61B17/12036 , A61B17/1204 , A61B17/12109 , A61F2/06 , A61F2/07 , A61F7/12 , A61F2007/0056 , A61F2210/0004 , A61F2250/0003 , A61M1/3613 , A61M25/0075 , A61M25/04 , A61M2025/1052 , A61M2025/1095
摘要： Devices and methods for controlling blood perfusion pressure. In an exemplary device for controlling blood perfusion pressure within a vessel of the present disclosure, the device comprises an elongated body having a lumen, a proximal end configured for placement in a first area having a first blood pressure, and a distal end configured for placement in a second area having a second blood pressure, partial occluder positioned within the lumen of the elongated body between the proximal end and the distal end, the partial occluder configured so not to fully occlude a blood vessel, wherein the partial occluder is configured to equalize the first blood pressure at the first area with the second blood pressure at the second area.
摘要翻译：用于控制血液灌注压力的装置和方法。在用于控制本公开的容器内的血液灌注压力的示例性装置中，该装置包括细长体，其具有内腔，近端被配置用于放置在具有第一血压的第一区域中，远端构造成用于放置在具有第二血压的第二区域中，位于所述细长体的所述内腔中的部分闭塞器位于所述近端和所述远端之间，所述部分闭塞器被构造成不能完全闭塞血管，其中所述部分闭塞器构造成使第一区域的第一血压在第二区域具有第二血压。

8. 发明授权

US08996106B2 Method and device for intermittent occlusion of a vein draining the organ system 有权
标题翻译：间歇性闭塞器官系统的方法和装置
公开(公告)号：US08996106B2
公开(公告)日：2015-03-31
申请号：US13959176
申请日：2013-08-05
申请人： Miracor Medical Systems GmbH
发明人： Werner Mohl
IPC分类号： A61M1/10 , A61B17/12 , A61M25/10 , A61M1/36 , A61B5/0215 , A61B17/00 , A61M25/00
CPC分类号： A61B17/12022 , A61B5/02152 , A61B17/12 , A61B17/1204 , A61B17/12136 , A61B2017/00557 , A61M1/106 , A61M1/1072 , A61M1/1086 , A61M1/125 , A61M1/3613 , A61M25/10181 , A61M2025/0002 , A61M2025/1052 , A61M2205/3344
摘要： In a method for the intermittent occlusion of a vein draining the organ system, in which the vein is occluded by an occlusion device, the fluid pressure in the occluded vein is continuously measured and stored, the behavior of the fluid pressure is determined as a function of time, and the occlusion of the vein is triggered and/or released as a function of at least one characteristic value derived from the pressure measurements, pressure is applied during the occlusion in a pulsating manner. The device for the intermittent occlusion of a vein, including an occlusion device, a pressure measuring device for continuously measuring the fluid pressure in the occluded vein, and a memory for storing the fluid pressure behavior as a function of time, means are provided for applying a pulsating pressure in the occluded vein.
摘要翻译：在间歇性闭塞排出脏器系统的静脉的方法中，其中静脉由闭塞装置吸入，连续测量和储存闭塞静脉中的流体压力，将流体压力的行为确定为功能的时间，并且根据从压力测量得到的至少一个特征值来触发和/或释放静脉的闭塞，并且以脉动方式在闭塞过程中施加压力。用于间歇性闭塞静脉的装置，包括闭塞装置，用于连续测量闭塞静脉中的流体压力的压力测量装置，以及用于存储作为时间的函数的流体压力特性的存储装置，用于施加闭塞静脉中的脉动压力。

9. 发明申请

US20150073329A1 SYSTEMS, DEVICES, AND METHODS FOR AUTORETROPERFUSION 有权
标题翻译：系统，设备和自动化方法
公开(公告)号：US20150073329A1
公开(公告)日：2015-03-12
申请号：US14546233
申请日：2014-11-18
申请人： CVDevices, LLC
发明人： Ghassan S. Kassab
IPC分类号： A61M1/36 , A61M25/04
CPC分类号： A61F2/856 , A61B5/02152 , A61B17/00234 , A61B2017/00243 , A61F2/958 , A61F2250/001 , A61F2250/0013 , A61M1/1008 , A61M1/1018 , A61M1/106 , A61M1/1072 , A61M1/1086 , A61M1/125 , A61M1/3613 , A61M1/3639 , A61M1/3653 , A61M1/3659 , A61M25/007 , A61M25/04 , A61M27/00 , A61M2025/1052 , A61M2025/1097 , A61M2205/3523 , A61M2205/3561 , A61M2205/50
摘要： Devices, systems, and methods for autoretroperfusion. In at least one embodiment of a perfusion system of the present disclosure, the system comprises a first catheter having a proximal end, a distal end, and a first lumen therethrough, the distal end configured for insertion into a luminal organ of a patient, a coupler defining an outlet port and a first port, the coupler configured to engage the proximal end of the first catheter at the outlet port and to receive blood from a blood supply through the first port, a first tube having a proximal end, a distal end, and a lumen therethrough, the distal end of the first tube configured to engage the first port of the coupler and to receive the blood from the blood supply, and a first flow regulator in communication with one or more of the coupler and the first tube, the first flow regulator operable to regulate a flow and/or a pressure of the blood through at least part of the system, wherein the system is configured to permit the blood from the blood supply to flow through the first tube, the coupler, and the first catheter into the patient to treat a patient condition.
摘要翻译：用于自体注射灌注的装置，系统和方法。在本公开的灌注系统的至少一个实施例中，该系统包括具有近端，远端和穿过其中的第一腔的第一导管，该远端构造成用于插入患者的管腔器官，所述联接器限定出口和第一端口，所述联接器构造成在所述出口处接合所述第一导管的近端并且从通过所述第一端口的血液供应器接收血液;第一管，其具有近端，远端以及其中的腔，所述第一管的远端构造成接合所述联接器的所述第一端口并且接收来自所述血液供应的血液;以及第一流量调节器，其与所述耦合器和所述第一管中的一个或多个连通，所述第一流量调节器可操作以通过所述系统的至少一部分来调节血液的流量和/或压力，其中所述系统被配置为允许来自所述血液供应的血液流过所述第一管， e耦合器，并且将第一导管插入患者以治疗患者状况。

10. 发明授权

US08968231B2 Method and device for removal of radiocontrast media from blood 有权
标题翻译：从血液中去除放射性对比介质的方法和装置
公开(公告)号：US08968231B2
公开(公告)日：2015-03-03
申请号：US13947549
申请日：2013-07-22
申请人： CHF Solutions, Inc.
发明人： Steven J. Bernard , John J. O'Mahony , Andrew V. Halpert , Mark Gelfand , Howard R. Levin
IPC分类号： A61M1/34 , A61M1/36 , B01D61/14 , B01D61/22
CPC分类号： A61M1/34 , A61M1/341 , A61M1/342 , A61M1/3431 , A61M1/3441 , A61M1/3451 , A61M1/36 , A61M1/3613 , A61M1/3615 , A61M1/3621 , A61M2205/15 , A61M2205/3331 , B01D61/145 , B01D61/22
摘要： An extracorporeal blood circuit including: a withdrawal conduit connectable to a coronary withdrawal catheter; a withdrawal pump connectable to the withdrawal conduit, wherein a pumping rate of the withdrawal pump determines a blood withdrawal rate from the coronary withdrawal catheter; a filter having an input connected to the withdrawal conduit and a blood output connected to an infusion conduit and a filtrate output connected to a filtrate conduit; a filtrate measurement device to determine an amount of filtrate removed from the blood in the filter; a fluid supplementation conduit providing a blood replacement fluid to at least one of the withdrawal conduit, filter and infusion conduit; a supplementation pump connectable to the fluid supplementation conduit, wherein a pumping rate of the supplementation pump determines a rate at which the blood replacement fluid flows into the blood flowing through the blood circuit, and a controller regulating the pumping rate of the supplementation pump such that the rate of the blood replacement fluid provides an amount of blood replacement fluid to the at least one of the withdrawal conduit, filter and infusion conduit so as to substantially match the amount of filtrate removed.
摘要翻译：一种体外血液回路，包括：可连接到冠状动脉取出导管的取出导管; 一个可连接到取出导管的抽吸泵，其中抽吸泵的泵送速率决定了冠状动脉取出导管的血液抽出速率; 过滤器，其具有连接到所述抽出管道的输入件，以及连接到输注管道的血液输出件和连接到滤液管道的滤液输出件; 滤液测量装置，用于确定从过滤器中的血液中除去的滤液量; 流体补充导管，其向至少一个取出导管，过滤器和输注导管提供血液置换流体; 补充泵可连接到流体补充导管，其中补充泵的泵送速率确定血液置换液体流入血液循环中的血液的速率，以及调节补充泵的泵送速率的控制器，使得血液置换液体的速率向抽出管道，过滤器和输注管道中的至少一个提供一定量的血液置换液体，以便基本上匹配除去的滤液量。

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