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    • 1. 发明授权
    • Methods and compositions for controlling biofouling using
fluorosurfactants
    • 使用含氟表面活性剂控制生物污垢的方法和组合物
    • US5879623A
    • 1999-03-09
    • US579365
    • 1995-12-27
    • Daniel E. GloverJoe C. SteelhammerStephen D. Bryant
    • Daniel E. GloverJoe C. SteelhammerStephen D. Bryant
    • A61K8/00A61K8/21A61K8/46A61Q11/00C02F1/50C02F5/14C11D1/00C11D1/02C23F11/00B01D17/04B01J13/00
    • A61K8/21A61Q11/00C02F1/50C02F5/14C11D1/004Y10S516/917Y10S516/92
    • The present invention relates to a method to inhibit bacteria from adhering to a submergible surface. The method contacts the submergible surface with an effective amount of at least one fluorosurfactant to inhibit bacterial adhesion to the submergible surface. The present invention also relates to a method for controlling biofouling of an aqueous system. This method adds an effective amount of at least one fluorosurfactant to inhibit bacteria from adhering to a submerged surface within the aqueous system. This method effectively controls biofouling without substantially killing the bacteria fouling organisms. The fluorosurfactant used in the method of the invention is an anionic or nonionic fluorosurfactant selected from: R.sub.f CH.sub.2 CH.sub.2 SCH.sub.2 CH.sub.2 CO.sub.2 Li, (R.sub.f CH.sub.2 CH.sub.2 O)P(O) (ONH.sub.4).sub.2, (R.sub.f CH.sub.2 CH.sub.2 O).sub.2 P(O) (ONH.sub.4), (R.sub.f CH.sub.2 CH.sub.2 O)P(O) (OH).sub.2, (R.sub.f CH.sub.2 CH.sub.2 O).sub.2 P(O) (OH), R.sub.f CH.sub.2 CH.sub.2 O (CH.sub.2 CH.sub.2 O).sub.x H, R.sub.f CH.sub.2 CH.sub.2 O(CH.sub.2 CH.sub.2 O).sub.y H, R.sub.f CH.sub.2 CH.sub.2 SO.sub.3 H, or mixtures thereof. The group R.sub.f is F(CF.sub.2 CF.sub.2).sub.3-8, x varies from 2-20, and y varies from 2-20. The present invention also relates to a compositions containing a fluorosurfactant and useable in the above methods. The compositions comprise at least one fluorosurfactant in an amount effective to inhibit bacteria from adhering to submergible or submerged surfaces.
    • 本发明涉及一种抑制细菌粘附在潜水表面上的方法。 该方法与有效量的至少一种含氟表面活性剂接触该潜水表面以抑制细菌粘附到潜水表面。 本发明还涉及一种用于控制水系统的生物污垢的方法。 该方法添加有效量的至少一种含氟表面活性剂以抑制细菌粘附到水系统内的浸没表面。 该方法有效地控制生物污染,而不会基本上杀死细菌污染生物体。 用于本发明方法的含氟表面活性剂是选自以下的阴离子或非离子氟表面活性剂:RfCH 2 CH 2 SCH 2 CH 2 CO 2 Li,(R f CH 2 CH 2 O)P(O)(ONH 4)2,(R f CH 2 CH 2 O)2 P(O)(ONH 4),(R f CH 2 CH 2 O) (OH)2,(RfCH 2 CH 2 O)2 P(O)(OH),RfCH 2 CH 2 O(CH 2 CH 2 O)x H,RfCH 2 CH 2 O(CH 2 CH 2 O)y H,RfCH 2 CH 2 SO 3 H或其混合物。 基团Rf是F(CF 2 CF 2)3-8,x从2-20变化,y从2-20变化。 本发明还涉及包含含氟表面活性剂并可在上述方法中使用的组合物。 组合物包含至少一种含氟表面活性剂,其含量有效地抑制细菌粘附到潜水或浸没的表面。
    • 2. 发明授权
    • Methods and compositions for controlling biofouling using N-alkyl
heterocyclic compounds
    • 使用N-烷基杂环化合物控制生物污损的方法和组合物
    • US5902808A
    • 1999-05-11
    • US536841
    • 1995-09-29
    • Marilyn S. WhittemoreDaniel E. GloverJoe C. SteelhammerStephen D. Bryant
    • Marilyn S. WhittemoreDaniel E. GloverJoe C. SteelhammerStephen D. Bryant
    • C02F1/00A01N43/40A01N43/84C02F1/50C09D5/14A61K31/535A01N43/00A01N43/36
    • C02F1/50C09D5/14
    • The present invention relates to a method to inhibit bacteria from adhering to a submergible surface. The method contacts the submergible surface with an effective amount of at least one N-alkyl heterocyclic compound to inhibit bacterial adhesion to the submergible surface. The present invention also relates to a method for controlling biofouling of an aqueous system. This method adds an effective amount of at least one N-alkyl heterocyclic compound to inhibit bacteria from adhering to a submerged surface within the aqueous system. This method effectively controls biofouling without substantially killing the fouling organisms. The N-alkyl heterocyclic compound used in the method of the invention has the following formula: ##STR1## The substituent R.sup.1 is a C.sub.8 -C.sub.20 alkyl group. The heterocyclic ring is a 5-8 membered heterocyclic ring where X is O, NH, or CH.sub.2. R.sup.2 is methyl, hydroxymethyl, or hydroxyethyl. The integer n ranges from 0 to 3. The present invention also relates to a composition containing N-alkyl heterocyclic compounds and useable in the above methods. The compositions comprise at least one N-alkyl heterocyclic compound in an amount effective to inhibit bacteria from adhering to submergible or submerged surfaces.
    • 本发明涉及一种抑制细菌粘附在潜水表面上的方法。 该方法用有效量的至少一种N-烷基杂环化合物接触潜表面以抑制细菌粘附到潜水表面。 本发明还涉及一种用于控制水系统的生物污垢的方法。 该方法添加有效量的至少一种N-烷基杂环化合物以抑制细菌粘附到水系统内的浸没表面。 该方法有效地控制生物污染,而不会基本上杀死污染的生物体。 用于本发明方法的N-烷基杂环化合物具有下式:取代基R 1为C 8 -C 20烷基。 杂环是5-8元杂环,其中X是O,NH或CH2。 R2是甲基,羟甲基或羟乙基。 整数n的范围为0-3。本发明还涉及含有N-烷基杂环化合物并可用于上述方法的组合物。 组合物包含至少一种有效抑制细菌粘附到潜水或浸没表面的N-烷基杂环化合物。