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1. 发明授权

US5605816A Recombinant DNA encoding PDGF A-chain polypeptides 失效
标题翻译：编码PDGF A链多肽的重组DNA
公开(公告)号：US5605816A
公开(公告)日：1997-02-25
申请号：US454425
申请日：1995-05-30
申请人： Carl-Henrik Heldin , Christer Betsholtz , Bengt Westermark , Timothy J. Knott , James Scott , Graeme I. Bell
发明人： Carl-Henrik Heldin , Christer Betsholtz , Bengt Westermark , Timothy J. Knott , James Scott , Graeme I. Bell
IPC分类号： C07K14/49 , C12N9/02 , C12N15/18 , C12N15/62 , C12N15/81 , C12N15/85 , C12N15/19
CPC分类号： C12N9/0089 , C07K14/49 , C12N15/62 , C12N15/81 , C12N15/85 , C07K2319/00 , C07K2319/02 , C07K2319/50 , C07K2319/75 , C12N2800/108 , C12N2830/002 , C12N2830/005 , C12N2830/15 , C12N2830/36 , C12N2830/55 , C12N2830/702
摘要： DNA encoding two forms of PDGF A-chain polypeptide, the construction of expression vectors for expressing such DNA in yeast and mammalian cells, and the expression of such DNA in yeast and mammalian cells to produce active PDGF A-chain homodimer and active PDGF A-chain/B-chain heterodimer are disclosed.
摘要翻译：编码两种形式的PDGF A链多肽的DNA，构建用于在酵母和哺乳动物细胞中表达这种DNA的表达载体，以及在酵母和哺乳动物细胞中表达这种DNA以产生活性PDGF A链同源二聚体和活性PDGFA- 链/ B链异源二聚体。

2. 发明授权

US06939849B1 Recombinant PDGF A-chain homodimers and methods of use 失效
标题翻译：重组PDGF A链同源二聚体及其使用方法
公开(公告)号：US06939849B1
公开(公告)日：2005-09-06
申请号：US08453350
申请日：1995-05-30
申请人： Carl-Henrik Heldin , Christer Betsholtz , Bengt Westermark , Timothy J. Knott , James Scott , Graeme I. Bell
发明人： Carl-Henrik Heldin , Christer Betsholtz , Bengt Westermark , Timothy J. Knott , James Scott , Graeme I. Bell
IPC分类号： C07K14/49 , C12N9/02 , C12N15/62 , C12N15/81 , C12N15/85 , A61K38/18 , C12N1/21 , C12N15/18 , C12N15/63
CPC分类号： C12N9/0089 , C07K14/49 , C07K2319/00 , C07K2319/02 , C07K2319/50 , C07K2319/75 , C12N15/62 , C12N15/81 , C12N15/85 , C12N2800/108 , C12N2830/002 , C12N2830/005 , C12N2830/15 , C12N2830/36 , C12N2830/55 , C12N2830/702
摘要： DNA encoding two forms of PDGF A-chain polypeptide, the construction of expression vectors for expressing such DNA in yeast and mammalian cells, and the expression of such DNA in yeast and mammalian cells to produce active PDGF A-chain homodimer and active PDGF A-chain/B-chain heterodimer are disclosed.
摘要翻译：编码两种形式的PDGF A链多肽的DNA，构建用于在酵母和哺乳动物细胞中表达这种DNA的表达载体，以及在酵母和哺乳动物细胞中表达这种DNA以产生活性PDGF A链同源二聚体和活性PDGFA- 链/ B链异源二聚体。

3. 发明授权

US5219759A Recombinant DNA encoding PDGF A-chain polypeptide and expression vectors 失效
标题翻译：编码PDGF A链多肽和表达载体的重组DNA
公开(公告)号：US5219759A
公开(公告)日：1993-06-15
申请号：US574540
申请日：1990-08-27
申请人： Carl-Henrik Heldin , Christer Betsholtz , Bengt Westermark , Timothy J. Knott , James Scott , Graeme I. Bell
发明人： Carl-Henrik Heldin , Christer Betsholtz , Bengt Westermark , Timothy J. Knott , James Scott , Graeme I. Bell
IPC分类号： C07K14/49 , C12N9/02 , C12N15/18 , C12N15/62 , C12N15/81 , C12N15/85
CPC分类号： C12N9/0089 , C07K14/49 , C12N15/62 , C12N15/81 , C12N15/85 , C07K2319/00 , C07K2319/02 , C07K2319/50 , C07K2319/75 , C12N2800/108 , C12N2830/002 , C12N2830/005 , C12N2830/15 , C12N2830/36 , C12N2830/55 , C12N2830/702
摘要： DNA encoding two forms of PDGF A-chain polypeptide, the construction of expression vectors for expressing such DNA in yeast and mammalian cells, and the expression of such DNA in yeast and mammalian cells to produce active PDGF A-chain homodimer and active PDGF A-chain/B-chain heterodimer are disclosed.
摘要翻译：编码两种形式的PDGF A链多肽的DNA，构建用于在酵母和哺乳动物细胞中表达这种DNA的表达载体，以及在酵母和哺乳动物细胞中表达这种DNA以产生活性PDGF A链同源二聚体和活性PDGFA- 链/ B链异源二聚体。

4. 发明申请

US20090277425A1 V-TYPE ENGINE WITH VALLEY-MOUNTED FUEL PUMP 有权
标题翻译： V型发动机与谷壳式燃油泵
公开(公告)号：US20090277425A1
公开(公告)日：2009-11-12
申请号：US12116722
申请日：2008-05-07
申请人： Peter M. Chisholm , Timothy J. Knott
发明人： Peter M. Chisholm , Timothy J. Knott
IPC分类号： F02F7/00 , B23P11/00
CPC分类号： F02M39/00 , F02B75/22 , F02M59/48 , Y10T29/49963
摘要： A V-type engine with an engine block face extending upward on at least one end of the valley includes a plurality of fasteners having a first threaded portion engaging the face of the engine block and a second threaded portion extending through the face into the valley and through corresponding apertures in a fuel pump housing mounting flange of a fuel pump disposed within the valley to secure the fuel pump directly to the engine block face without an adapter plate. The second threaded portion of each fastener engages a complementarily threaded spacer with a proximate end securing the flange of the fuel pump housing to the back of the engine block face and extending into the valley along substantially the entire length of the fuel pump housing to a distal end shaped to facilitate engagement with a fastening tool.
摘要翻译：具有在谷的至少一端向上延伸的发动机块面的V型发动机包括多个紧固件，所述多个紧固件具有接合发动机缸体表面的第一螺纹部分和穿过所述面部延伸到所述谷部中的第二螺纹部分，通过设置在谷内的燃料泵的燃料泵壳体安装凸缘中的相应的孔，以将燃料泵直接固定到发动机缸体面，而无需适配器板。每个紧固件的第二螺纹部分接合互补螺纹的间隔件，近端将燃料泵壳体的凸缘固定到发动机缸体表面的后部，并且沿燃料泵壳体的大致整个长度延伸到谷部中，端部成形以便于与紧固工具接合。

5. 发明授权

US08943670B2 Composite engine part and fastener assembly and method of securing a composite part to an engine 有权
标题翻译：复合发动机部件和紧固件组件以及将复合部件固定到发动机的方法
公开(公告)号：US08943670B2
公开(公告)日：2015-02-03
申请号：US13588244
申请日：2012-08-17
申请人： John Carl Lohr , Christopher William Newman , Timothy J. Knott
发明人： John Carl Lohr , Christopher William Newman , Timothy J. Knott
IPC分类号： B23P11/00 , F16B39/282
CPC分类号： F16B39/24 , F16B39/282 , Y10T29/49948 , Y10T29/49964
摘要： A method of securing a composite plastic part to an engine with a bolt or a bolt and washer. The bolt has a head including teeth that are adapted to engage either the part or the washer. The bolt is tightened to cause the teeth to compress the surface of the part to resist rotation that may become loosened as a result of vibration of the engine. The part may be an intake manifold, a cam cover or an oil pan. Locking features, such as teeth, may be provided on the clamping surface of the bolt and on both surfaces of the washer. Alternatively, a knurled or serrated surface may be provided instead of the teeth.
摘要翻译：用螺栓或螺栓和垫圈将复合塑料部件固定到发动机的方法。螺栓具有包括适于接合零件或垫圈的齿的头部。螺栓被拧紧，导致齿压缩零件的表面以抵抗由于发动机的振动而可能松动的旋转。该部件可以是进气歧管，凸轮盖或油盘。可以在螺栓的夹紧表面和垫圈的两个表面上提供锁定特征，例如齿。或者，可以提供滚花或锯齿状表面而不是齿。

6. 发明申请

US20140047700A1 Composite Engine Part and Fastener Assembly and Method of Securing a Composite Part to an Engine 有权
标题翻译：复合发动机部件和紧固件组件以及将复合部件固定到发动机的方法
公开(公告)号：US20140047700A1
公开(公告)日：2014-02-20
申请号：US13588244
申请日：2012-08-17
申请人： John Carl Lohr , Christopher William Newman , Timothy J. Knott
发明人： John Carl Lohr , Christopher William Newman , Timothy J. Knott
IPC分类号： F16B39/24 , F16B39/282 , B23P11/00
CPC分类号： F16B39/24 , F16B39/282 , Y10T29/49948 , Y10T29/49964
摘要： A method of securing a composite plastic part to an engine with a bolt or a bolt and washer. The bolt has a head including teeth that are adapted to engage either the part or the washer. The bolt is tightened to cause the teeth to compress the surface of the part to resist rotation that may become loosened as a result of vibration of the engine. The part may be an intake manifold, a cam cover or an oil pan. Locking features, such as teeth, may be provided on the clamping surface of the bolt and on both surfaces of the washer. Alternatively, a knurled or serrated surface may be provided instead of the teeth.
摘要翻译：使用螺栓或螺栓和垫圈将复合塑料部件固定到发动机的方法。螺栓具有包括适于接合零件或垫圈的齿的头部。螺栓被拧紧，导致齿压缩零件的表面以抵抗由于发动机的振动而可能松动的旋转。该部件可以是进气歧管，凸轮盖或油盘。可以在螺栓的夹紧表面和垫圈的两个表面上提供锁定特征，例如齿。或者，可以提供滚花或锯齿状表面而不是齿。

7. 发明授权

US07762239B2 V-type engine with valley-mounted fuel pump 有权
标题翻译： V型发动机带谷式燃油泵
公开(公告)号：US07762239B2
公开(公告)日：2010-07-27
申请号：US12116722
申请日：2008-05-07
申请人： Peter M. Chisholm , Timothy J. Knott
发明人： Peter M. Chisholm , Timothy J. Knott
IPC分类号： F02M37/04 , F02B75/22
CPC分类号： F02M39/00 , F02B75/22 , F02M59/48 , Y10T29/49963
摘要： A V-type engine with an engine block face extending upward on at least one end of the valley includes a plurality of fasteners having a first threaded portion engaging the face of the engine block and a second threaded portion extending through the face into the valley and through corresponding apertures in a fuel pump housing mounting flange of a fuel pump disposed within the valley to secure the fuel pump directly to the engine block face without an adapter plate. The second threaded portion of each fastener engages a complementarily threaded spacer with a proximate end securing the flange of the fuel pump housing to the back of the engine block face and extending into the valley along substantially the entire length of the fuel pump housing to a distal end shaped to facilitate engagement with a fastening tool.
摘要翻译：具有在谷的至少一端向上延伸的发动机块面的V型发动机包括多个紧固件，所述多个紧固件具有接合发动机缸体表面的第一螺纹部分和穿过所述面部延伸到所述谷部中的第二螺纹部分，通过设置在谷内的燃料泵的燃料泵壳体安装凸缘中的相应的孔，以将燃料泵直接固定到发动机缸体面，而无需适配器板。每个紧固件的第二螺纹部分接合互补螺纹的间隔件，近端将燃料泵壳体的凸缘固定到发动机缸体表面的后部，并且沿燃料泵壳体的大致整个长度延伸到谷部中，端部成形以便于与紧固工具接合。

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