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    • 10. 发明申请
    • Devices, methods, and kits for non-invasive glucose measurement
    • 用于非侵入性葡萄糖测量的装置,方法和试剂盒
    • US20060004271A1
    • 2006-01-05
    • US11159587
    • 2005-06-22
    • Thomas PeyserRussell PottsHerbert BermanJames MoyerMikhail Kouchnir
    • Thomas PeyserRussell PottsHerbert BermanJames MoyerMikhail Kouchnir
    • A61B5/00
    • A61B5/1455A61B5/14521A61B5/14532A61B2562/0295G01N33/66G06F19/00
    • Described are devices, methods, and kits for non-invasively measuring glucose. In general, the devices comprise skin patches for placement on a skin surface and measurement devices for measuring glucose collected in the patches. The patches may include an adhesive material, a collection layer, an interface layer, and a sweat-permeable membrane. The sweat-permeable membrane is configured to act as a barrier to epidermal contaminants and glucose brought to the skin surface via diffusion. In this way, non-correlatable skin surface glucose will not be measured. The patches may further include components to induce a local sweat response. The measurement device typically includes a display, a processor, and a measurement mechanism. The methods typically include the steps of wiping the skin surface with a wipe containing at least one solvent for removing glucose, placing a patch on a skin surface, and measuring glucose collected in the patch. Kits comprising the patch and measurement device are also described.
    • 描述了用于非侵入性测量葡萄糖的装置,方法和试剂盒。 通常,这些装置包括用于放置在皮肤表面上的皮肤贴片和用于测量在贴片中收集的葡萄糖的测量装置。 贴剂可以包括粘合剂材料,收集层,界面层和汗液渗透膜。 透汗膜被配置为作为通过扩散带到皮肤表面的表皮污染物和葡萄糖的屏障。 以这种方式,不能测量不相关的皮肤表面葡萄糖。 补片还可以包括诱发局部汗水反应的组件。 测量装置通常包括显示器,处理器和测量机构。 所述方法通常包括以下步骤:用含有至少一种用于除去葡萄糖的溶剂的擦拭物擦拭皮肤表面,将贴片放置在皮肤表面上,以及测量在贴剂中收集的葡萄糖。 还描述了包括贴剂和测量装置的试剂盒。