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1. 发明授权

US06440368B1 Automatic handler for feeding containers into and out of an analytical instrument 有权
标题翻译：用于将容器进出分析仪器的自动处理机
公开(公告)号：US06440368B1
公开(公告)日：2002-08-27
申请号：US09504273
申请日：2000-02-15
申请人： Beri Cohen , Thomas W. DeYoung , Krunoslav Esteban Draganovic , Paul E. Purpura
发明人： Beri Cohen , Thomas W. DeYoung , Krunoslav Esteban Draganovic , Paul E. Purpura
IPC分类号： G01N110
CPC分类号： G01N35/04 , G01N35/026 , G01N2035/00752 , G01N2035/0465 , G01N2035/0493 , G01N2035/1025 , Y10T436/11 , Y10T436/113332 , Y10T436/114165 , Y10T436/2575
摘要： A sample handler moves and positions sample tube racks in an analytical instrument. The sample handler has an in-feed and out-feed that advance sample tube racks using a walking beam mechanism. Sample tube racks are seated within the in-feed and are transported onto a cross-feed. The cross-feed comprises a movable track having a platform mounted thereto. The platform includes spring loaded gripper fingers that engages and secures the sample tube rack to the platform. The cross-feed moves the sample tube racks to a point where they are accessed by the analytical instrument. Thereafter, the cross-feed moves the sample tube racks to a position behind the out-feed where the walking beam mechanism moves the tube racks out of the analytical instrument.
摘要翻译：样品处理器将样品管架移动并放置在分析仪器中。样品处理器具有进料和出料，使用步进梁机构推进样品管架。样品管架位于进料内，并被运送到交叉进料。交叉进给包括具有安装在其上的平台的活动轨道。该平台包括弹簧加载的夹持器手指，其将样品管架接合并固定到平台。交叉进给将样品管架移动到分析仪器访问的位置。此后，交叉进给将样品管架移动到出料口后面的位置，其中步进梁机构将管架移出分析仪器。

2. 发明授权

US06489169B1 Automatic handler for feeding containers into and out of an analytical instrument 有权
标题翻译：用于将容器进出分析仪器的自动处理机
公开(公告)号：US06489169B1
公开(公告)日：2002-12-03
申请号：US09500982
申请日：2000-02-15
申请人： Beri Cohen , Thomas W. DeYoung , Krunoslav Esteban Draganovic , Paul E. Purpura
发明人： Beri Cohen , Thomas W. DeYoung , Krunoslav Esteban Draganovic , Paul E. Purpura
IPC分类号： G01N3502
CPC分类号： G01N35/04 , G01N35/026 , G01N2035/00752 , G01N2035/0465 , G01N2035/0493 , G01N2035/1025 , Y10T436/11 , Y10T436/113332 , Y10T436/114165 , Y10T436/2575
摘要： A method for feeding containers into an analytical instrument whereby a sample handler moves and positions racks, containing sample tubes, into, within and out of the analytical instrument. The sample handler has an in-feed and out-feed that advance sample tube racks using a walking beam mechanism. The racks are seated within the in-feed and are transported onto a cross-feed. The cross-feed moves the racks to a position behind the out-feed where the walking beam mechanism moves the tube racks out of the analytical instrument.
摘要翻译：一种用于将容器送入分析仪器的方法，由此样品处理器将包含样品管的机架移动并放置在分析仪器内，进出分析仪器。样品处理器具有进料和出料，使用步进梁机构推进样品管架。机架位于进料内，并被运送到交叉进给。交叉进给将机架移动到出料口后面的位置，其中步进梁机构将管架移出分析仪器。

3. 发明授权

US06444472B1 Automatic handler for feeding containers into and out of an analytical instrument 有权
标题翻译：用于将容器进出分析仪器的自动处理机
公开(公告)号：US06444472B1
公开(公告)日：2002-09-03
申请号：US09500940
申请日：2000-01-15
申请人： Beri Cohen , Thomas W. DeYoung , Krunoslav Esteban Draganovic , Paul E. Purpura
发明人： Beri Cohen , Thomas W. DeYoung , Krunoslav Esteban Draganovic , Paul E. Purpura
IPC分类号： G01N3502
CPC分类号： G01N35/04 , G01N35/026 , G01N2035/00752 , G01N2035/0465 , G01N2035/0493 , G01N2035/1025 , Y10T436/11 , Y10T436/113332 , Y10T436/114165 , Y10T436/2575
摘要： A method whereby a sample handler moves and positions racks, containing sample tubes, in an analytical instrument. The sample handler has an in-feed and out-feed that advance sample tube racks using a walking beam mechanism. The racks are seated within the in-feed and are transported onto a cross-feed. The racks and tubes contained thereon are moved past detection devices that identify the samples and measure various properties thereof. Thereafter, the cross-feed moves the racks to a position behind the out-feed where the walking beam mechanism moves the tube racks out of the analytical instrument.
摘要翻译：样品处理器在分析仪器中移动并定位包含样品管的机架的方法。样品处理器具有进料和出料，使用步进梁机构推进样品管架。机架位于进料内，并被运送到交叉进给。包含在其上的机架和管被移动通过识别样品并测量其各种性质的检测装置。此后，交叉进给将机架移动到出料口后面的位置，在步行梁机构将管架移出分析仪器。

4. 发明授权

US06426228B1 Method for feeding containers into and out of an analytical instrument 有权
标题翻译：容器进出分析仪器的方法
公开(公告)号：US06426228B1
公开(公告)日：2002-07-30
申请号：US09504272
申请日：2000-02-15
申请人： Beri Cohen , Thomas W. DeYoung , Krunoslav Esteban Draganovic , Paul E. Purpura
发明人： Beri Cohen , Thomas W. DeYoung , Krunoslav Esteban Draganovic , Paul E. Purpura
IPC分类号： G01N3504
CPC分类号： G01N35/04 , G01N35/026 , G01N2035/00752 , G01N2035/0465 , G01N2035/0493 , G01N2035/1025 , Y10T436/11 , Y10T436/113332 , Y10T436/114165 , Y10T436/2575
摘要： A method whereby a sample handler moves and positions racks, containing sample tubes, in an analytical instrument. The sample handler has an in-feed and out-feed that advance sample tube racks using a walking beam mechanism. The racks are seated within the in-feed and are transported onto a cross-feed. The racks and tubes contained thereon are moved past detection devices that identify the samples and measure various properties thereof. Thereafter, the cross-feed moves the racks to a position behind the out-feed where the walking beam mechanism moves the tube racks out of the analytical instrument.
摘要翻译：样品处理器在分析仪器中移动并定位包含样品管的机架的方法。样品处理器具有进料和出料，使用步进梁机构推进样品管架。机架位于进料内，并被运送到交叉进给。包含在其上的机架和管被移动通过识别样品并测量其各种性质的检测装置。此后，交叉进给将机架移动到出料口后面的位置，在步行梁机构将管架移出分析仪器。

5. 发明授权

US06451259B1 Automatic handler for feeding containers into and out of an analytical instrument 有权
标题翻译：用于将容器进出分析仪器的自动处理机
公开(公告)号：US06451259B1
公开(公告)日：2002-09-17
申请号：US09500974
申请日：2000-02-15
申请人： Beri Cohen , Thomas W. DeYoung , Krunoslav Esteban Draganovic , Paul E. Purpura
发明人： Beri Cohen , Thomas W. DeYoung , Krunoslav Esteban Draganovic , Paul E. Purpura
IPC分类号： G01N3502
CPC分类号： G01N35/04 , G01N35/026 , G01N2035/00752 , G01N2035/0465 , G01N2035/0493 , G01N2035/1025 , Y10T436/11 , Y10T436/113332 , Y10T436/114165 , Y10T436/2575
摘要： Racks having sample containers mounted therein are transported within an analytical system so that a robotic arm can remove the sample containers and deliver them to a desired location within the system. The sample handler has an in-feed and out-feed that advance sample tube racks using a walking beam mechanism. Sample tube racks are seated within the in-feed and are transported onto a cross-feed. The cross-feed comprises a movable track having a platform mounted thereto. The cross-feed moves the sample tube racks from a position behind the in-feed to a position behind the out-feed where the walking beam mechanism moves the tube racks out of the analytical instrument.
摘要翻译：安装有样品容器的机架在分析系统内运输，使得机器人手臂可以移除样品容器并将其输送到系统内的期望位置。样品处理器具有进料和出料，使用步进梁机构推进样品管架。样品管架位于进料内，并被运送到交叉进料。交叉进给包括具有安装在其上的平台的活动轨道。交叉进给将样品管架从进料中的位置移动到出料口后面的位置，其中步进梁机构将管架移出分析仪器。

6. 发明授权

US06426044B1 Automatic handler for feeding containers into and out of an analytical instrument 有权
公开(公告)号：US06426044B1
公开(公告)日：2002-07-30
申请号：US09504366
申请日：2000-02-15
申请人： Beri Cohen , Thomas W. DeYoung , Krunoslav Esteban Draganovic , Paul E. Purpura
发明人： Beri Cohen , Thomas W. DeYoung , Krunoslav Esteban Draganovic , Paul E. Purpura
IPC分类号： G01N3504
CPC分类号： G01N35/04 , G01N35/026 , G01N2035/00752 , G01N2035/0465 , G01N2035/0493 , G01N2035/1025 , Y10T436/11 , Y10T436/113332 , Y10T436/114165 , Y10T436/2575
摘要： Racks having sample containers mounted therein are transported within an analytical system so that a robotic arm can remove the sample containers and deliver them to a desired location within the system. The sample handler has an in-feed and out-feed that advance sample tube racks using a walking beam mechanism. Sample tube racks are seated within the in-feed and are transported onto a cross-feed. The cross-feed comprises a movable track having a platform mounted thereto. The cross-feed moves the sample tube racks from a position behind the in-feed to a position behind the out-feed where the walking beam mechanism moves the tube racks out of the analytical instrument.

7. 发明授权

US06426043B1 Automatic handler for feeding containers into and out of an analytical instrument 有权
标题翻译：用于将容器进出分析仪器的自动处理机
公开(公告)号：US06426043B1
公开(公告)日：2002-07-30
申请号：US09503918
申请日：2000-02-15
申请人： Beri Cohen , Thomas W. DeYoung , Krunoslav Esteban Draganovic , Paul E. Purpura
发明人： Beri Cohen , Thomas W. DeYoung , Krunoslav Esteban Draganovic , Paul E. Purpura
IPC分类号： G01N3504
CPC分类号： G01N35/04 , G01N35/026 , G01N2035/00752 , G01N2035/0465 , G01N2035/0493 , G01N2035/1025 , Y10T436/11 , Y10T436/113332 , Y10T436/114165 , Y10T436/2575
摘要： A sample handler moves and positions racks, containing sample tubes, in an analytical instrument. The sample handler has an in-feed and out-feed that advance sample tube racks using a walking beam mechanism. The racks are seated within the in-feed and are transported onto a cross-feed. The racks and tubes contained thereon are moved past detection devices that identify the samples and measure various properties thereof. Thereafter, the cross-feed moves the racks to a position behind the out-feed where the walking beam mechanism moves the tube racks out of the analytical instrument.
摘要翻译：样品处理器将包含样品管的机架移动并放置在分析仪器中。样品处理器具有进料和出料，使用步进梁机构推进样品管架。机架位于进料内，并被运送到交叉进给。包含在其上的机架和管被移动通过识别样品并测量其各种性质的检测装置。此后，交叉进给将机架移动到出料口后面的位置，在步行梁机构将管架移出分析仪器。

8. 发明授权

US06331437B1 Automatic handler for feeding containers into and out of an analytical instrument 失效
标题翻译：用于将容器进出分析仪器的自动处理机
公开(公告)号：US06331437B1
公开(公告)日：2001-12-18
申请号：US09115391
申请日：1998-07-14
申请人： Beri Cohen , Thomas W. DeYoung , Krunoslav Esteban Draganovic , Paul E. Purpura
发明人： Beri Cohen , Thomas W. DeYoung , Krunoslav Esteban Draganovic , Paul E. Purpura
IPC分类号： G01N3502
CPC分类号： G01N35/04 , G01N35/026 , G01N2035/00752 , G01N2035/0465 , G01N2035/0493 , G01N2035/1025 , Y10T436/11 , Y10T436/113332 , Y10T436/114165 , Y10T436/2575
摘要： An analytical instrument has a sample handler for inputting racks of containers, including various types and sizes of test tubes, both capped and uncapped, and inserts, into the instrument. The sample handler has an infeed, an outfeed and a cross-feed between the infeed and outfeed. The infeed and outfeed advance the racks of containers using walking beam mechanisms which lift the racks by tabs on the right and left sides of the rack, which are positioned at a substantially identical height. Racks input into the infeed are transferred by the walking beam mechanism to a track on the cross-feed. They are then pushed, by a transport subassembly having a platform with pivotable pusher fingers to cam the rack and to push it in only one direction, from behind the infeed to a fixed position behind the outfeed.
摘要翻译：分析仪器具有用于输入容器架的样品处理器，包括各种类型和尺寸的试管（封盖和未封盖）以及插入到仪器中。样品处理器在进料和出料之间具有进料，出料和交叉进料。进料和出料使用步进梁机构推进集装箱架，其通过位于基本上相同高度的机架的右侧和左侧的突出部提升机架。输入进料口的机架由步进梁机构传送到交叉进给的轨道上。然后，它们被具有平台的运输子组件推动，该平台具有可枢转的推动器指状物，以便使齿条收缩并将其仅在一个方向上推动，从进料后方移动到出料器后面的固定位置。

9. 发明授权

US06257091B1 Automatic decapper 失效
标题翻译：自动拆包机
公开(公告)号：US06257091B1
公开(公告)日：2001-07-10
申请号：US09115777
申请日：1998-07-14
申请人： Beri Cohen , Thomas W. DeYoung , Paul E. Purpura , Helmut Artus
发明人： Beri Cohen , Thomas W. DeYoung , Paul E. Purpura , Helmut Artus
IPC分类号： B67B700
CPC分类号： B67B7/182 , G01N2035/0405 , G01N2035/1025
摘要： An automatic decapper removes caps from capped test tubes by gripping the cap on a test tube with the upper grippers and holding the cap stationary while the test tube is rotated and translated downward with lower grippers. In a preferred embodiment, the upper grippers comprise three jaws coupled to a cam to be moved, as appropriate, from a first position in which a test tube cap may be inserted between the jaws to a second position in which the jaws grip the inserted cap. The upper grippers are mounted to a decapping arm that is pivotable between a first position above the lower grippers, in which the decapping takes place, to a second position above the exterior of the decapper, where it remains while the test tube is inserted into or removed from the lower grippers and where a removed cap may be released into a container for disposal or reuse. The lower grippers comprise a pair of lever arms for holding the test tube. The lower grippers form part of a rotatable assembly that moves up towards the upper grippers and down away from the upper grippers along a lead screw. A pair of half-gears mounted at a fixed vertical position are used to separate the lever arms for insertion and removal of the test tube when the rotatable assembly is vertically positioned with the lever arms adjacent the half-gears. An ultrasonic sensor may be positioned on the decapping arm above the upper grippers to detect the liquid level of the sample in the test tube after the cap has been removed and the decapping arm is returned to its first position. A liquid sensor comprising a prism and two fiber optic cables is mounted in a reservoir under lower grippers and is used to detect if there has been spillage from a test tube in the lower grippers.
摘要翻译：自动去皮包装机通过用上夹具夹住试管上的盖子，并在试管旋转的同时将盖子固定，同时用下夹具向下平移，从盖上的试管中清除盖子。在优选实施例中，上夹具包括联接到凸轮上的三个钳口，所述凸轮适当地从第一位置移动到第二位置，在该第一位置，试管帽可以插入到夹爪之间到第二位置，在该第二位置，夹爪夹持插入的盖。上夹具安装到开盖臂上，该开盖臂可在下夹具之间的第一位置（在其中进行开盖的位置）之间枢转到脱扣器外部上方的第二位置，其中在试管被插入或从下夹具中移除，并且其中移除的盖可以被释放到容器中用于处理或再利用。下夹具包括一对用于保持试管的杠杆臂。下夹具形成可旋转组件的一部分，其可以沿着导螺杆向上移动朝向上夹具并向上移动远离上夹持器。当可旋转组件在杠杆臂相邻于半齿轮时垂直定位时，使用安装在固定垂直位置的一对半齿轮来分离杠杆臂以插入和移除试管。超声波传感器可以位于上夹具上方的开盖臂上，以在帽被去除并且开盖臂返回到其第一位置之后检测试管中的样品的液面。包括棱镜和两根光纤电缆的液体传感器安装在下夹具下方的容器中，并用于检测下夹具中的试管是否已经溢出。

10. 发明授权

US06227053B1 Dynamic noninvasive detection of analytical container feature using ultrasound 失效
标题翻译：使用超声波动态无创检测分析容器特征
公开(公告)号：US06227053B1
公开(公告)日：2001-05-08
申请号：US09115393
申请日：1998-07-14
申请人： Paul E. Purpura , Ralph Waters , Olivier Landier , Beri Cohen
发明人： Paul E. Purpura , Ralph Waters , Olivier Landier , Beri Cohen
IPC分类号： G01N2900
CPC分类号： G01N29/4427 , G01F23/296 , G01N29/07 , G01N2035/009 , G01N2035/1025 , G01N2291/011 , G01N2291/02836 , G01N2291/02881 , G01N2291/044 , G01N2291/2695
摘要： A profile of a rack, that may have zero, one, or a plurality of containers may be obtained using an ultrasonic sensor. The sensor emits a plurality of ultrasonic bursts and the rack is transported under the sensor at a slew speed that allows the sensor to detect at least first and second echoes from each of the bursts. Data points, corresponding to each of the first and second echoes, are generated and the data points are captured in a memory device. The data points, generally reflecting the levels of the rack and any containers, are processed to dynamically and non-invasively (i.e., without physically contacting the liquid with a probe) determine information about the container types, whether any container is capped, and, if one or more containers are uncapped, the liquid level in the uncapped containers. This profiling may be used in a variety of devices and is particularly useful in a sample handler in an automated analytical instrument, where the ultrasonic sensor may be positioned above a rack transport mechanism.
摘要翻译：可以使用超声波传感器获得可以具有零个，一个或多个容器的齿条的轮廓。传感器发射多个超声波脉冲串，并且机架以传感器在传感器的下方传输，允许传感器从每个脉冲串中检测至少第一和第二回波。生成对应于第一和第二回波中的每一个的数据点，并将数据点捕获在存储器件中。通常反映机架和任何容器的水平的数据点被动态和非侵入性地处理（即，没有物理地将液体与探头接触）确定关于容器类型的信息，无论任何容器是否被盖住，如果一个或多个容器未封盖，则未封盖的容器中的液面。该分析可用于各种设备中，并且在自动分析仪器中的样品处理器中特别有用，其中超声波传感器可以位于机架传送机构上方。

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