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1. 发明申请

US20090225543A1 Optical system for batwing distribution 有权
标题翻译：蝙蝠分配光学系统
公开(公告)号：US20090225543A1
公开(公告)日：2009-09-10
申请号：US12074762
申请日：2008-03-05
申请人： Benjamin A. Jacobson , Robert D. Gengelbach , Nicholas W. Medendorp, JR. , Lawrence Roberts , John Perry
发明人： Benjamin A. Jacobson , Robert D. Gengelbach , Nicholas W. Medendorp, JR. , Lawrence Roberts , John Perry
IPC分类号： F21V7/00 , G02B17/00 , G21G4/00 , A61N5/06
CPC分类号： F21V13/04 , F21S4/28 , F21V5/007 , F21V5/04 , F21V29/004 , F21V29/505 , F21V29/71 , F21V29/763 , F21W2131/103 , F21Y2101/00 , F21Y2103/10 , F21Y2105/10 , F21Y2115/10 , G02B27/095 , H01L33/54
摘要： A radiation distribution system designed to produce a batwing distribution. The system may be used with radiative sources emitting in the visible spectrum or in other spectra. The system comprises a specially shaped lens disposed over a radiative source, such as an LED, for example. The lens and source are arranged between two reflector bodies, both of which have an elongated reflective surface that faces the source. The reflector bodies each have two different reflective surfaces that face outward and away from each other. The lens and both reflective surfaces work in concert to redirect a portion of the emitted radiation to create the desired batwing distribution. Several sources may be arranged linearly between a single pair of reflector bodies on a common surface to create a linear array of sources. Likewise, multiple linear arrays may be combined to form a two-dimensional array. In the two-dimensional configuration, linear arrays of sources are disposed on both sides of a reflector body, so that both of the reflective surfaces are utilized.
摘要翻译：设计用于产生蝙蝠分布的辐射分布系统。该系统可以与在可见光谱或其它光谱中发射的辐射源一起使用。该系统包括例如设置在辐射源（例如LED）上的特殊形状的透镜。透镜和光源布置在两个反射体之间，两个反射体具有面向光源的细长反射表面。反射体各自具有面向外且彼此远离的两个不同的反射表面。透镜和两个反射表面一起工作以重定向发射的辐射的一部分以产生所需的蝙蝠分布。可以在公共表面上的单对反射体之间线性布置若干源，以产生线阵列的源。同样，可以组合多个线性阵列以形成二维阵列。在二维构造中，源极的线性阵列设置在反射体的两侧，从而利用两个反射表面。

2. 发明授权

US09557033B2 Optical system for batwing distribution 有权
标题翻译：蝙蝠分配光学系统
公开(公告)号：US09557033B2
公开(公告)日：2017-01-31
申请号：US12074762
申请日：2008-03-05
申请人： Benjamin A. Jacobson , Robert D. Gengelbach , Nicholas W. Medendorp, Jr. , Lawrence Roberts , John Perry
发明人： Benjamin A. Jacobson , Robert D. Gengelbach , Nicholas W. Medendorp, Jr. , Lawrence Roberts , John Perry
IPC分类号： F21V3/00 , F21V5/00 , F21V13/04 , F21V5/04 , G02B27/09 , F21V29/71 , F21V29/76 , F21V29/00 , F21W131/103 , H01L33/54 , F21V29/505 , F21Y101/00
CPC分类号： F21V13/04 , F21S4/28 , F21V5/007 , F21V5/04 , F21V29/004 , F21V29/505 , F21V29/71 , F21V29/763 , F21W2131/103 , F21Y2101/00 , F21Y2103/10 , F21Y2105/10 , F21Y2115/10 , G02B27/095 , H01L33/54
摘要： A radiation distribution system designed to produce a batwing distribution. The system may be used with radiative sources emitting in the visible spectrum or in other spectra. The system comprises a specially shaped lens disposed over a radiative source, such as an LED, for example. The lens and source are arranged between two reflector bodies, both of which have an elongated reflective surface that faces the source. The reflector bodies each have two different reflective surfaces that face outward and away from each other. The lens and both reflective surfaces work in concert to redirect a portion of the emitted radiation to create the desired batwing distribution. Several sources may be arranged linearly between a single pair of reflector bodies on a common surface to create a linear array of sources. Likewise, multiple linear arrays may be combined to form a two-dimensional array. In the two-dimensional configuration, linear arrays of sources are disposed on both sides of a reflector body, so that both of the reflective surfaces are utilized.
摘要翻译：设计用于产生蝙蝠分布的辐射分布系统。该系统可以与在可见光谱或其它光谱中发射的辐射源一起使用。该系统包括例如设置在辐射源（例如LED）上的特殊形状的透镜。透镜和光源布置在两个反射体之间，两个反射体具有面向光源的细长反射表面。反射体各自具有面向外且彼此远离的两个不同的反射表面。透镜和两个反射表面一起工作以重定向发射的辐射的一部分以产生所需的蝙蝠分布。可以在公共表面上的单对反射体之间线性布置若干源，以产生线阵列的源。同样，可以组合多个线性阵列以形成二维阵列。在二维构造中，源极的线性阵列设置在反射体的两侧，从而利用两个反射表面。

3. 发明申请

US20120122137A1 Novel Nitroreductase Enzymatic Substrates 有权
标题翻译：新型硝基还原酶酶底物
公开(公告)号：US20120122137A1
公开(公告)日：2012-05-17
申请号：US13387295
申请日：2010-07-29
申请人： Olivier Fabrega , Arthur James , Sylvain Orenga , John Perry , Vindhya Salwatura , Stephen Stanforth
发明人： Olivier Fabrega , Arthur James , Sylvain Orenga , John Perry , Vindhya Salwatura , Stephen Stanforth
IPC分类号： C12Q1/26 , C07D209/20 , C07D263/56 , C07D209/12 , C07D235/06 , C07D277/64
CPC分类号： C12Q1/26 , C12Q1/04
摘要： The invention relates to the use of a compound having formula (I) as an enzymatic substrate for the detection of a nitroreductase activity, wherein: W1, W2, W3 and W4 are independently H, Br, Cl, F, I, alkyl, alkoxy, thiomethyl, perfluoroalkyl, nitro, cyano, carboxyl (including the esters or amides thereof) or any combination of same; n=0, 1 or 2; X is NR, CZ5Z6, S or O, R being H, alkyl, aralkyl, aryl, alkanoic or alkylsulphonie, Z5 and Z6 being an alkyl; Y is N or N+R, R being alkyl, aralkyl, aryl, alkanoic or alkylsulphonic; Z1, Z2, Z3 and Z4 are independently H, Br, Cl, F, I, alkyl, aryl, alkoxy, perfluoroalkyl, nitro, cyano, carboxyl, sulphonyl, including the sulphonyl or carboxyl amides or esters thereof, and the salts of same.
摘要翻译：本发明涉及式（I）化合物作为酶底物用于检测硝基还原酶活性的用途，其中：W1，W2，W3和W4独立地为H，Br，Cl，F，I，烷基，烷氧基，硫代甲基，全氟烷基，硝基，氰基，羧基（包括其酯或酰胺）或其任何组合; n = 0,1或2; X是NR，CZ5Z6，S或O，R是H，烷基，芳烷基，芳基，链烷酸或烷基磺酸，Z5和Z6是烷基; Y是N或N + R，R是烷基，芳烷基，芳基，链烷酸或烷基磺酸; Z 1，Z 2，Z 3和Z 4独立地是H，Br，Cl，F，I，烷基，芳基，烷氧基，全氟烷基，硝基，氰基，羧基，磺酰基，包括磺酰基或羧基酰胺或其酯。

4. 发明申请

US20100297692A1 REACTION MEDIUM FOR DETECTING AND/OR IDENTTIFYING STAPHYLOCCOUS AUREUS 审中-公开
标题翻译：用于检测和/或鉴定印刷油墨的反应介质
公开(公告)号：US20100297692A1
公开(公告)日：2010-11-25
申请号：US12734454
申请日：2008-11-25
申请人： Diane Halimi , Sylvain Orenga , John Perry
发明人： Diane Halimi , Sylvain Orenga , John Perry
IPC分类号： C12Q1/14
CPC分类号： C12Q1/04 , C12Q1/045 , G01N33/56938 , G01N2333/31
摘要： A reaction medium for characterizing Staphylococcus aureus, that includes a metabolic indicator which is a beta-ribosidase substrate in combination with at least one other metabolic indicator and/or at least one metabolic regulator. A method for detecting and/or identifying Staphylococcus aureus, including: providing a reaction medium that comprises a metabolic indicator which is a beta-ribosidase substrate in combination with at least one other metabolic indicator and/or at least one metabolic regulator; inoculating the medium with a biological sample to be tested; allowing for incubation; and characterizing the presence of Staphylococcus aureus.
摘要翻译：用于表征金黄色葡萄球菌的反应介质，其包括与至少一种其它代谢指示剂组合的β-核糖酶底物和/或至少一种代谢调节剂的代谢指示剂。一种用于检测和/或鉴定金黄色葡萄球菌的方法，包括：提供包含与至少一种其它代谢指示剂组合的β-核糖酶底物的代谢指示剂和/或至少一种代谢调节剂的反应介质; 用待测试的生物样品接种培养基; 允许孵化; 并表征金黄色葡萄球菌的存在。

5. 发明申请

US20100069814A1 SYSTEM AND METHOD FOR UTILIZING MICROBUBBLES AND LIPOSOMES AS VIRAL SEQUESTERING AGENTS 审中-公开
标题翻译：用作病毒序列代理的微生物和脂质体的系统和方法
公开(公告)号：US20100069814A1
公开(公告)日：2010-03-18
申请号：US12211748
申请日：2008-09-16
申请人： Anthony V. Borgia , John Perry
发明人： Anthony V. Borgia , John Perry
IPC分类号： A61M37/00 , A61K9/12 , A61K9/127
CPC分类号： A61K9/127 , A61K47/6911 , A61K47/6925
摘要： A system and method of utilizing microbubbles and liposomes as viral sequestering agents. Microbubbles and liposomes having polyanions and conjugation systems are injected into the bloodstream of a subject human or animal. The microbubbles and/or liposomes attract virus particles including envelope viruses. After the microbubbles and/or liposomes have circulated in the blood for a pre-established time period, the microbubbles and/or liposomes along with attached virus particles are separated from the blood of the subject by passing the blood over or through a substrate or using a centrifuge. The substrate includes a conjugation system which has an affinity for the polyanions of the microbubbles and/or liposomes. As the microbubbles and/or liposomes and attached virus particles are removed from the blood, the viral titer of the subject is lowered. The microbubbles and/or liposomes may also be mixed with blood and filtered outside of the subject such that the microbubbles and/or liposomes are never in the bloodstream of the subject.
摘要翻译：利用微泡和脂质体作为病毒螯合剂的系统和方法。具有聚阴离子和缀合系统的微泡和脂质体被注射到受试者人或动物的血流中。微泡和/或脂质体吸引病毒颗粒，包括包膜病毒。在微泡和/或脂质体在血液中循环预先确定的时间段之后，将微泡和/或脂质体连同附着的病毒颗粒通过使血液通过或通过底物或使用离心机底物包括对微泡和/或脂质体的聚阴离子具有亲和力的共轭体系。当从血液中除去微泡和/或脂质体和附着的病毒颗粒时，受试者的病毒滴度降低。微泡和/或脂质体也可以与血液混合并在受试者之外过滤，使得微泡和/或脂质体永远不在受试者的血液中。

6. 发明申请

US20100062467A1 Medium For Detecting And/Or Identifying Bacteria 有权
标题翻译：用于检测和/或识别细菌的培养基
公开(公告)号：US20100062467A1
公开(公告)日：2010-03-11
申请号：US12448895
申请日：2008-02-07
申请人： Daniel Monget , Sylvain Orenga , John Perry , Michel Peyret , Celine Roger-Dalbert
发明人： Daniel Monget , Sylvain Orenga , John Perry , Michel Peyret , Celine Roger-Dalbert
IPC分类号： C12Q1/34 , C12Q1/44 , C12Q1/37 , C12Q1/04
CPC分类号： C12Q1/10
摘要： The invention relates to a method for detecting and/or identifying Escherichia coli (E. coli) in a biological sample, that comprises inoculating the biological sample liable to contain E. coli on a detection medium that comprises tryptophan and a substrate for an enzyme A, expressed by the majority of E. coli, in order to obtain bacterial colonies; detecting the colonies expressing the activity of the enzyme A and identifying them as being E. coli; and detecting the colonies that do not express the activity of the enzyme A, carrying out an indole test, and identifying the colonies having a positive indole test as being E. coli.
摘要翻译：本发明涉及用于在生物样品中检测和/或鉴定大肠杆菌（E.coli）的方法，其包括在包含色氨酸和酶A底物的检测培养基上接种容易含有大肠杆菌的生物样品，由大多数大肠杆菌表达，以获得细菌菌落; 检测表达酶A活性的菌落，并将其鉴定为大肠杆菌; 并检测不表达酶A的活性的菌落，进行吲哚试验，并鉴定具有阳性吲哚试验的菌落为大肠杆菌。

7. 发明申请

US20070167729A1 Highly constrained magnetic resonance spectroscopy image reconstruction method 有权
标题翻译：高度约束的磁共振光谱图像重建方法
公开(公告)号：US20070167729A1
公开(公告)日：2007-07-19
申请号：US11524838
申请日：2006-09-21
申请人： Charles Mistretta , Scott Reeder , John Perry , Oliver Wieben
发明人： Charles Mistretta , Scott Reeder , John Perry , Oliver Wieben
IPC分类号： A61B5/05
CPC分类号： G01R33/485 , G01R33/4824 , G01R33/5608 , G01R33/561
摘要： A series of image frames are acquired in which an MR parameter such as echo time (TE) is changed and the resulting image frames are employed to produce an MRS image of a metabolite. Scan time is reduced without sacrificing image quality by reconstructing a composite image from data acquired for a plurality of the image frames and using a highly constrained image reconstruction method with the composite image to produce each image frame.
摘要翻译：获取一系列图像帧，其中诸如回波时间（TE）的MR参数改变，并且使用所得到的图像帧来产生代谢物的MRS图像。通过从针对多个图像帧获取的数据重建合成图像并且使用具有合成图像的高度约束的图像重建方法来产生每个图像帧，从而降低了扫描时间，而不牺牲图像质量。

8. 发明申请

US20060257966A1 Medium for detection and identification of micro-organisms 有权
标题翻译：用于微生物检测和鉴定的培养基
公开(公告)号：US20060257966A1
公开(公告)日：2006-11-16
申请号：US10552508
申请日：2004-04-02
申请人： Sylvain Orenga , Celine Roger-Dalbert , John Perry , Arthur James
发明人： Sylvain Orenga , Celine Roger-Dalbert , John Perry , Arthur James
IPC分类号： C12Q1/04
CPC分类号： C12Q1/045 , C12Q1/10
摘要： The invention relates to a medium for detecting and/or identifying microorganisms present in a sample, comprising a culture medium and at least one substrate that can be hydrolysed to a labelled product by at least a first enzyme not free in the sample, and specific for the microorganisms, characterized in that it also comprises at least one inhibitor of at least a second enzyme, different from the first enzyme or identical to it, but free in said sample and not originating from a microorganism. The present invention also finds a preferred application in the field of biomedical diagnosis or in food microbiology, and more particularly in bacteriology and mycology.
摘要翻译：本发明涉及一种用于检测和/或鉴定样品中存在的微生物的培养基，其包含培养基和至少一种可通过样品中不含游离的至少第一种酶水解成标记产物的底物，并且特异于所述微生物的特征在于，其还包含至少一种与第一种酶不同的第二种酶的至少一种抑制剂，或与之相同，但在所述样品中游离并且不来自微生物。本发明还发现在生物医学诊断或食品微生物学领域中的优选应用，更特别地在细菌学和真菌学领域。

9. 发明申请

US20060059830A1 Roof and wall covering with improved corner construction 有权
标题翻译：屋顶和墙壁覆盖物，改善角落结构
公开(公告)号：US20060059830A1
公开(公告)日：2006-03-23
申请号：US10912707
申请日：2004-08-05
申请人： John Perry
发明人： John Perry
IPC分类号： E04D1/00
CPC分类号： E04D1/3402 , E04D1/30 , E04D2001/305 , E04F13/0864
摘要： A wall covering for a pair of wall surfaces that form a corner. The wall covering includes (1) plurality of wall panels each having a plurality of horizontal tiers of simulated building elements and (2) a plurality of corner moldings each having a single tier of building elements. The corner moldings each have mounting flanges and an interlock and alignment pin that facilitate adjustable positioning of the corner molding with a selected tier of building elements of an adjacent wall panel. The corner molding mounting flanges and building elements further define relatively deep wall panel receiving pockets for positively retaining the side of an adjacent wall panel and forming a water barrier.
摘要翻译：用于形成角落的一对墙壁的墙壁。墙壁覆盖物包括（1）多个墙板，每个壁板具有多个水平层的模拟建筑构件，以及（2）多个角落模制件，每个具有单层建筑构件。角落模具各自具有安装凸缘和互锁和对准销，其有助于角部模具与相邻壁板的选定层的构建元件的可调定位。角落模制安装法兰和建筑元件进一步限定相对较深的壁板接收袋，用于积极地保持相邻壁板的侧面并形成防水屏障。

10. 发明申请

US20050003899A1 Leg positioning and training device for golfers 失效
标题翻译：高尔夫球手的腿部定位和训练装置
公开(公告)号：US20050003899A1
公开(公告)日：2005-01-06
申请号：US10601367
申请日：2003-06-23
申请人： John Perry
发明人： John Perry
IPC分类号： A63B69/36
CPC分类号： A63B69/3667 , A63B2069/367
摘要： A leg positioning and training device for a golfer is disclosed. The device is characterized by the structure including platform having a foot base plate rotatably mounted thereon for the golfer's rear foot, wherein the foot base plate is adjustable in two planes. The foot base plate includes a segment that extends upwardly from the base plate in receiving relation to the user's foot and ankle, and this segment is angularly adjustable with respect to a plane that is substantially normal to the foot base plate. A strain gauge is operatively attached to that segment for receiving and measuring force applied by the user, and a display indicator is provided in operative connection to the strain gauge, whereby the user may see a representation of the force applied thereto during a golf swing.
摘要翻译：公开了一种用于高尔夫球手的腿部定位和训练装置。该装置的特征在于包括平台，该平台具有用于高尔夫球手的后脚可旋转地安装在其上的脚底板，其中脚底板可在两个平面中调节。脚底板包括从基板向上延伸的部分，其以与使用者的脚和脚踝接收的关系延伸，并且该部分相对于基本上垂直于脚底板的平面成角度地调节。应变计可操作地附接到该段用于接收和测量由用户施加的力，并且显示指示器被提供为与应变计可操作地连接，由此用户可以在高尔夫挥杆期间看到施加到其上的力的表示。

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