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1. 发明授权

US09486581B2 Injector device with force lock-out and injection rate limiting mechanisms 有权
公开(公告)号：US09486581B2
公开(公告)日：2016-11-08
申请号：US11102882
申请日：2005-04-11
申请人： John Lovell , Robert E. West , Todd M. Chelak , William Easterbrook , Mark A. Follman , Edward P. Browka
发明人： John Lovell , Robert E. West , Todd M. Chelak , William Easterbrook , Mark A. Follman , Edward P. Browka
IPC分类号： A61M5/315 , A61M5/20 , A61M5/28 , A61M5/46 , A61M5/32
CPC分类号： A61M5/20 , A61M5/28 , A61M5/315 , A61M5/31551 , A61M5/31561 , A61M5/31571 , A61M5/3158 , A61M5/31593 , A61M5/3202 , A61M5/46 , A61M2005/2013
摘要： An injectable substance delivery device comprising a pen device body, a cartridge, a plunger, a drive mechanism, and at least one of a lock-out mechanism and a rate-limiting mechanism. The lock-out mechanism is provided through a ratchet engagement between the body and the plunger to restrict plunger movement and to ensure that the required needle puncture depth is realized prior to injection by locking out the injection mechanism from advancing until a specified force is applied to the skin. A rate-limiting mechanism is also provided through a user compressed plunger drive spring to ensure that a specific rate of injection is realized during the injection of a medicament.

2. 发明申请

US20130066271A1 NEEDLE ASSEMBLY WITH NEEDLE INJECTION DEPTH ADJUSTMENT 有权
标题翻译：针头装配针头深度调整
公开(公告)号：US20130066271A1
公开(公告)日：2013-03-14
申请号：US13698686
申请日：2010-05-17
申请人： Robert E. West
发明人： Robert E. West
IPC分类号： A61M5/46 , A61M5/32
CPC分类号： A61M5/46 , A61M5/3257 , A61M5/3271
摘要： In one aspect, a needle assembly is provided herein which includes a hub; a needle fixed to the hub, the needle having a proximal end and a distal end, the distal end formed for insertion into a patient; and, a body disposed on the hub so as to be moveable relative thereto, the body having a distal end with an aperture formed therein configured to permit passage therethrough of the needle. The body is releasably retainable in a first position on the hub where the distal end of the needle extends distally a first distance from the distal end of the body. Also, the body is retainable in a second position on the hub where the distal end of the needle extends distally a second distance from the distal end of the body, the second distance being less than the first distance. The hub is displaceable proximally relative to the body to urge the body from the first position to the second position. Advantageously, with the subject invention, a needle assembly is provided which may provide a stop for a needle injection to a first depth, with the stop being adjustable to permit the injection to be conducted at a shallower, second depth.
摘要翻译：在一个方面，本文提供了一种针组件，其包括毂; 固定到所述轮毂的针，所述针具有近端和远端，所述远端形成为用于插入患者体内; 以及设置在所述轮毂上以能够相对于其移动的本体，所述主体具有远端，所述远端形成在其中，所述孔形成为允许针穿过所述针。主体可释放地保持在轮毂上的第一位置，其中针的远端从主体的远端向远侧延伸第一距离。此外，身体可保持在轮毂上的第二位置，其中针的远端从身体的远端向远侧延伸第二距离，第二距离小于第一距离。轮毂相对于主体向近侧移位，以将身体从第一位置推动到第二位置。有利地，在本发明中，提供了一种针组件，其可以提供用于针注射到第一深度的止挡件，其中止动件是可调节的，以允许注射在较浅的第二深度进行。

3. 发明申请

US20120220567A1 BENZO-FUSED OXAZEPINE COMPOUNDS AS STEAROYL-COENZYME A DELTA-9 DESATURASE INHIBITORS 审中-公开
标题翻译：苯并呋喃氧化合物作为硬脂醇聚醚A DELTA-9去饱和酶抑制剂
公开(公告)号：US20120220567A1
公开(公告)日：2012-08-30
申请号：US13386533
申请日：2010-07-21
申请人： Gerald W. Shipps, JR. , Zhiwei Yang , Yongqi Deng , Robert E. West, JR. , Dineshwar P. Sinha
发明人： Gerald W. Shipps, JR. , Zhiwei Yang , Yongqi Deng , Robert E. West, JR. , Dineshwar P. Sinha
IPC分类号： A61K31/553 , A61P3/10 , A61P5/48 , A61P3/00 , A61P7/00 , A61P1/16 , A61P17/00 , A61P3/06 , A61P9/10 , C07D498/10 , A61P3/04
CPC分类号： C07D498/10
摘要： The present invention relates to certain 4,5-dihydro-3H-spiro[benzo[b]-[1,4]oxazepine compounds of the Formula (I) or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R4, R5, m, n, o, and p are as herein described. In addition, the invention relates to compositions comprising at least one such compound, and methods of using the compounds for treating or preventing disorders such as non-insulin dependent (Type 2) diabetes, insulin resistance, hyperglycemia, a lipid disorder, obesity, fatty liver disease, or a skin disorder.
摘要翻译：本发明涉及式（I）的某些4,5-二氢-3H-螺[苯并[b] - [1,4]恶唑烷化合物或其药学上可接受的盐，其中R1，R2，R3，R4， R5，m，n，o和p如本文所述。此外，本发明涉及包含至少一种这样的化合物的组合物，以及使用该化合物治疗或预防诸如非胰岛素依赖型（2型）糖尿病，胰岛素抵抗，高血糖症，脂质障碍，肥胖症，脂肪酸肝脏疾病或皮肤病症。

4. 发明授权

US07192405B2 Integrated lancet and bodily fluid sensor 有权
标题翻译：集成的柳叶刀和体液传感器
公开(公告)号：US07192405B2
公开(公告)日：2007-03-20
申请号：US10259798
申请日：2002-09-30
申请人： John D. DeNuzzio , Steven Keith , Lawrence A. Monahan , Phyllis Palmer , Bill Stewart , Todd M. Chelak , Robert E. West , William Allen , Frederick Karl , Lee Griswold
发明人： John D. DeNuzzio , Steven Keith , Lawrence A. Monahan , Phyllis Palmer , Bill Stewart , Todd M. Chelak , Robert E. West , William Allen , Frederick Karl , Lee Griswold
IPC分类号： A61B5/00
CPC分类号： A61B5/1486 , A61B5/150022 , A61B5/150305 , A61B5/150358 , A61B5/150412 , A61B5/150503 , A61B5/150618 , A61B5/150725 , A61B5/15107 , A61B5/15117 , A61B5/1519 , A61B5/15194 , A61B2562/0295 , Y10T29/49002 , Y10T29/49826
摘要： A lancing device integrated with a sensing strip and method of making and using the same are provided. A lance and analyte sensing strip are combined in a single, preferably disposable, device. In a preferred embodiment, a slot is provided in a support member so the lance can be engaged by a lance driver and driven into the skin producing a bodily fluid sample from a wound. The sensing area of the sensing strip is adjacent to the wound location reducing dexterity requirements for patients.
摘要翻译：提供了与传感带集成的穿刺装置及其制造和使用方法。喷枪和分析物感测带组合在单个，优选一次性的装置中。在优选实施例中，在支撑构件中设置狭槽，使得喷枪能够由喷枪驱动器接合并被驱动到皮肤中，从伤口产生体液样品。传感带的传感区域与伤口位置相邻，可减少对患者的灵活性要求。

5. 发明授权

US06491709B2 Alternate-site lancer 有权
标题翻译：替代现场的舞者
公开(公告)号：US06491709B2
公开(公告)日：2002-12-10
申请号：US09745947
申请日：2000-12-22
申请人： Ashutosh Sharma , Amir A. Sharifi-Mehr , Robert E. West , Robert J. Strowe
发明人： Ashutosh Sharma , Amir A. Sharifi-Mehr , Robert E. West , Robert J. Strowe
IPC分类号： A61B1734
CPC分类号： A61B5/150022 , A61B5/150068 , A61B5/150427 , A61B5/150503 , A61B5/150717 , A61B5/150824 , A61B5/15113 , A61B5/15117 , A61B5/1513 , A61B5/1519 , A61B5/15194
摘要： A new tip for a conventional lancer that provides for improved blood flow from a lancet puncture site not located on a patient's finger. The new lancer tip includes a plurality of crenellations that exert rotational force on the skin surrounding the lancet puncture site when the lancer is rotated to enhance blood flow from the lancet puncture site.
摘要翻译：传统的乳房的新提示，其提供来自不位于患者手指上的刺血针穿刺部位的改善的血流量。新的乳头尖端包括多个扇形，当摇床转动以增加来自刺血针穿刺部位的血液流动时，在刺血针穿刺部位周围的皮肤上施加旋转力。

6. 发明授权

US5873462A Pen needle dispenser 失效
标题翻译：笔针机
公开(公告)号：US5873462A
公开(公告)日：1999-02-23
申请号：US928691
申请日：1997-09-12
申请人： Tuan V. Nguyen , Michael A. DiBiasi , Robert E. West
发明人： Tuan V. Nguyen , Michael A. DiBiasi , Robert E. West
IPC分类号： A61M5/00 , A61M5/32 , B65D83/02
CPC分类号： B65D83/02 , A61M5/002 , A61M5/3205
摘要： A pen needle dispenser having a cover rotatably mounted on a circular shaped container having a plurality of cavities, with each cavity dimensioned to receive a pen needle assembly with or without shields. The cover includes a slot that is rotated into alignment with one of the cavities in the container to provide the user with access to one unused shielded pen needle and thereby permits the pen needle to be mounted on a medication delivery pen. After use the used unshielded pen needle is returned to and locked in the cavity. Then, the cover is rotated until the slot is aligned with another cavity containing the next unused shielded pen needle to be used during the next injection. The pen needle dispenser prevents the cover from rotating the slot back to cavities containing used pen needles.
摘要翻译：一种笔针分配器，其具有可旋转地安装在具有多个空腔的圆形容器上的盖，每个空腔的尺寸被设计成接收具有或不具有屏蔽的笔式针组件。盖子包括与容器中的其中一个空腔旋转成对准的槽，以使使用者能够进入一个未使用的屏蔽笔针，从而允许笔针安装在药物输送笔上。使用后，使用的非屏蔽笔针返回并锁定在空腔中。然后，旋转盖子，直到狭槽与下一次注射期间要使用的下一个未使用的屏蔽笔针的另一个空腔对齐。笔针分配器防止盖将槽旋转回包含用过的笔针的空腔。

7. 发明授权

US4716923A Apparatus for manipulating parallel fluid flow circuits 失效
标题翻译：用于操纵平行流体流动回路的装置
公开(公告)号：US4716923A
公开(公告)日：1988-01-05
申请号：US879411
申请日：1986-06-27
申请人： Robert E. West
发明人： Robert E. West
IPC分类号： F16K11/085 , F16K11/06
CPC分类号： F16K11/0856 , Y10T137/5762 , Y10T137/86566 , Y10T137/86726 , Y10T137/86751 , Y10T137/86871
摘要： Apparatus for manipulating at least two fluid flow circuits comprising a manifold, and a valve stem assembly with at least two stages in series, with each stage comprising a valve relief for communicating with at least two inlet and outlet ports, and a seal for blocking off or isolating a port. The apparatus of the invention allows at least two fluid flow circuits to be connected to the manifold in a parallel configuration to operate in a redundant manner. If the conduit or a fluid control or monitoring device within a circuit fails or requires maintenance, that particular circuit may be isolated from the process flow system by the multiple flow directing capability of the apparatus. Use of the apparatus of the invention enables the removal of valve devices or conduit in a circuit for repair or replacement without interrupting the on-line process fluid flow.
摘要翻译：用于操纵包括歧管的至少两个流体流动回路的装置和具有至少两个级联的阀杆组件，每个级包括用于与至少两个入口和出口连通的阀浮标，以及用于阻断的密封件或隔离端口。本发明的装置允许至少两个流体流动回路以并联结构连接到歧管以以冗余的方式操作。如果电路内的导管或流体控制或监测装置发生故障或需要维护，则该特定电路可以通过装置的多个流动导向能力与过程流系统隔离。使用本发明的装置能够在电路中去除用于修理或更换的电路中的阀装置或导管，而不会中断在线过程流体流动。

8. 发明授权

US4006359A Pipeline crawler 失效
标题翻译：管道履带
公开(公告)号：US4006359A
公开(公告)日：1977-02-01
申请号：US79859
申请日：1970-10-12
申请人： James R. Sullins , Robert E. West
发明人： James R. Sullins , Robert E. West
IPC分类号： G01M3/00 , G01N21/00 , B61B13/10 , G01N23/00
CPC分类号： G01M3/005
摘要： A crawler is disclosed for traveling through a workpiece such as a pipeline and inspecting the same for defects. The crawler is a completely self-contained, self-propelled and self-operated vehicle adapted to travel through a pipeline, stop at particular locations such as a girth weld between adjoining sections of pipe, inspect the weld, for example by X-raying it and then proceed onto the next location to be inspected.
摘要翻译：公开了用于行进通过诸如管道的工件的履带，并检查其是否存在缺陷。履带是一种完全独立的自行车和自行车辆，适用于穿过管道，停在特定位置，例如管道相邻部分之间的环形焊缝，检查焊缝，例如通过X射线然后进入下一个要检查的位置。

9. 发明申请

US20120011705A1 Integrated lancet and bodily fluid sensor 有权
标题翻译：集成的柳叶刀和体液传感器
公开(公告)号：US20120011705A1
公开(公告)日：2012-01-19
申请号：US12929261
申请日：2011-01-11
申请人： John D. DeNuzzio , Steven Keith , Lawrence A. Monahan , Phyllis Palmer , Bill Stewart , Todd M. Chelak , Robert E. West , William Allen , Frederick Karl , Lee Griswold
发明人： John D. DeNuzzio , Steven Keith , Lawrence A. Monahan , Phyllis Palmer , Bill Stewart , Todd M. Chelak , Robert E. West , William Allen , Frederick Karl , Lee Griswold
IPC分类号： H05K13/00 , B23P11/00
CPC分类号： A61B5/1486 , A61B5/150022 , A61B5/150305 , A61B5/150358 , A61B5/150412 , A61B5/150503 , A61B5/150618 , A61B5/150725 , A61B5/15107 , A61B5/15117 , A61B5/1519 , A61B5/15194 , A61B2562/0295 , Y10T29/49002 , Y10T29/49826
摘要： A lancing device integrated with a sensing strip and method of making and using the same are provided. A lance and analyte sensing strip are combined in a single, preferably disposable, device. In a preferred embodiment, a slot is provided in a support member so the lance can be engaged by a lance driver and driven into the skin producing a bodily fluid sample from a wound. The sensing area of the sensing strip is adjacent to the wound location reducing dexterity requirements for patients.
摘要翻译：提供了与传感带集成的穿刺装置及其制造和使用方法。喷枪和分析物感测带组合在单个，优选一次性的装置中。在优选实施例中，在支撑构件中设置狭槽，使得喷枪可以由喷枪驱动器接合并被驱动到皮肤中，从伤口产生体液样品。传感带的传感区域与伤口位置相邻，可减少对患者的灵活性要求。

10. 发明授权

US07926681B2 Method and apparatus for dispensing diagnostic test strips 有权
标题翻译：用于分配诊断测试条的方法和装置
公开(公告)号：US07926681B2
公开(公告)日：2011-04-19
申请号：US12461937
申请日：2009-08-28
申请人： Robert E. West , John Lovell
发明人： Robert E. West , John Lovell
IPC分类号： G06F11/00
CPC分类号： G01N33/48757
摘要： An apparatus for storing and dispensing a test strip includes a container configured to store a radial array of test strips. The container maintains appropriate environmental conditions, such as humidity, for storing the test strips. The container has a plurality of radially extending slots formed by a plurality of dividing walls, and each slot is sized to receive a single test strip. A rotatably positionable cover is carried by the container for covering the plurality of radially extending slots. The cover includes an opening, which, when the cover rotates, aligns with one of the slots at a time to allow removal of a single test strip located within the respective slot. Accordingly, the unused test strips remain free of contaminants such as naturally occurring skin oils on a user's hand.
摘要翻译：用于存储和分配测试条的设备包括被配置为存储测试条的径向阵列的容器。容器保持适当的环境条件，例如湿度，用于存放测试条。容器具有由多个分隔壁形成的多个径向延伸的狭槽，并且每个狭槽的尺寸被设计成容纳单个测试条。可旋转定位的盖由容器承载以覆盖多个径向延伸的槽。盖子包括一个开口，当盖子转动时，一个开口与其中一个插槽对准，以允许移除位于相应插槽内的单个测试条。因此，未使用的测试条在用户的手上保持无污染物，例如天然存在的皮肤油。

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