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1. 发明申请

US20180304027A1 Injection Device 审中-公开
公开(公告)号：US20180304027A1
公开(公告)日：2018-10-25
申请号：US16017794
申请日：2018-06-25
申请人： Sanofi
发明人： William Marsh , Anthony Paul Morris , Joseph Butler , Matthew Jones
IPC分类号： A61M5/315
CPC分类号： A61M5/31583 , A61M5/20 , A61M5/24 , A61M5/31541 , A61M5/3155 , A61M5/31553 , A61M5/31561 , A61M5/31568 , A61M5/3157 , A61M2005/3125 , A61M2005/3126 , A61M2205/581 , A61M2205/582 , A61M2205/583
摘要： The invention refers to a handheld injection device comprising a housing, a dose indicator positioned within and axially constrained to the housing and rotatable with respect to the housing during dose setting and during dose dispensing, a gauge element, which is at least partly interposed between the housing and the dose indicator, wherein the gauge element is axially guided within the housing and in threaded engagement with the dose indicator such that rotation of the dose indicator causes an axial displacement of the gauge element. A contrast element having a first marking is provided and at least a region of the gauge element is provided with a second marking, with the first marking and/or the second marking being visible through a first window or aperture in the housing depending on the axial position of the gauge element within the housing.

2. 发明申请

US20180147351A1 METHOD AND DEVICE FOR DELIVERING A SUBCUTANEOUS DOSE THROUGH MULTIPLE INJECTIONS 审中-公开
公开(公告)号：US20180147351A1
公开(公告)日：2018-05-31
申请号：US15824056
申请日：2017-11-28
申请人： PORTAL INSTRUMENTS, INC.
发明人： Patrick Anquetil , Ian Hunter
IPC分类号： A61M5/20 , A61M5/315 , A61M5/31
CPC分类号： A61M5/204 , A61M5/1409 , A61M5/24 , A61M5/30 , A61M5/3134 , A61M5/31535 , A61M5/31556 , A61M5/31561 , A61M5/3158 , A61M5/46 , A61M2005/31588 , A61M2205/505 , A61M2205/52 , A61M2205/581 , A61M2205/582 , A61M2205/583 , A61M2205/6063
摘要： A method of administering subcutaneous treatment to a patient is provided. The method includes delivering, by a needle-free injection device, a first volume of a treatment at a first location on a surface of a body of the patient; detecting a movement of the needle-free injection device relative to the first location; determining, from the movement of the needle-free injection device relative to the first location, a second location of the needle-free injection device relative to the first location; determining a second volume of the treatment to deliver at the surface of the body of the patient at the second location; and delivering, by the needle-free injection device, the second volume of the treatment at the second location on the surface of the body of the patient.

3. 发明授权

US09861757B2 Injection device with an end of dose feedback mechanism 有权
公开(公告)号：US09861757B2
公开(公告)日：2018-01-09
申请号：US15241566
申请日：2016-08-19
申请人： Novo Nordisk A/S
发明人： Claus Schmidt Moller , Bo Radmer , Lars Ulrik Nielsen , Christian Peter Enggaard
IPC分类号： A61M5/315 , A61M5/20 , A61M5/24
CPC分类号： A61M5/3157 , A61M5/20 , A61M5/24 , A61M5/31535 , A61M5/3155 , A61M5/31551 , A61M5/31561 , A61M5/31585 , A61M2205/581 , A61M2205/582
摘要： An injection device with a dose delivering mechanism being adapted to provide a non-visual, e.g. audible and/or tactile, feedback signal when a set dose has been at least substantially injected. A first and a second part of the injection device are adapted to perform a relative rotational movement with respect to each other. The relative rotational movement causes at least two parts of the injection device to abut or engage, and this abutment or engagement causes the non-visual feedback signal to be generated. A very distinct and precise feedback is provided as compared to prior art axial solutions because the generation of the feedback signal is initiated by the relative rotational movement.Feedback signal may be generated by a change in a rotational velocity of at least one part, e.g. by changing the pitch of a threaded portion or by engaging a non-rotating part and a rotating part, thereby causing the non-rotating part to start rotating. May alternatively be generated by building up and releasing a tension.The injection device is suitable for injecting insulin.

4. 发明申请

US20170340831A1 MEDICAMENT DELIVERY DEVICE 审中-公开
公开(公告)号：US20170340831A1
公开(公告)日：2017-11-30
申请号：US15673207
申请日：2017-08-09
申请人： SHL GROUP AB
发明人： Lucio Giambattista , Antonio Bendek , Ling-Hsiang Chao
IPC分类号： A61M5/315 , A61M5/31 , A61M5/24
CPC分类号： A61M5/31551 , A61M5/24 , A61M5/31541 , A61M5/31553 , A61M5/31561 , A61M5/3158 , A61M5/31595 , A61M2005/2407 , A61M2005/3126 , A61M2205/581 , A61M2205/582
摘要： A dose setting mechanism for a medicament delivery device is presented having a locking assembly that reliably and consistently unlocks a dose injection button and concurrently a lead screw when the dose setting mechanism is transitioned from a non-activated state to an activated state. This locking assembly uses a rotating plate having a locking protrusion that engages a radial projecting tab on a rotationally fixed plunger rod nut. An alignment member is also presented that prevents rotational drift of a dosing member.

5. 发明授权

US09827373B2 Torsion spring injection device having an end-of-dose mechanism 有权
公开(公告)号：US09827373B2
公开(公告)日：2017-11-28
申请号：US14895302
申请日：2014-06-02
申请人： Novo Nordisk A/S
发明人： Simon Roervig , Steffen Hansen
IPC分类号： A61M5/20 , A61M5/315 , A61M5/24 , A61M5/48 , A61M5/32
CPC分类号： A61M5/20 , A61M5/24 , A61M5/2466 , A61M5/3155 , A61M5/31553 , A61M5/31561 , A61M5/3157 , A61M5/3158 , A61M5/31583 , A61M5/486 , A61M2005/2013 , A61M2005/2407 , A61M2005/3267 , A61M2205/43 , A61M2205/581
摘要： The present invention relates to a torsion spring based automatic injection device for apportioning set doses of a liquid drug and which injection device is provided with an End-of-Dose feedback mechanism providing a user with an audible signal once the set dose has been injected. During injection, the scale drum rotates back to its “zero” position under influence of the torsion spring. This rotation is halted shortly before reaching the “zero” position by stopping means. The scale drum is thereafter only allowed to continue rotation and thus reach the “zero” position once the torque applied to the scale drum by the torsion spring surpasses a threshold value.

6. 发明授权

US09802001B2 Dispensing speed control mechanism and injection device 有权
公开(公告)号：US09802001B2
公开(公告)日：2017-10-31
申请号：US14782745
申请日：2014-04-08
申请人： SANOFI
发明人： Daniel David Higgins , Matthew Jones , Joseph Butler , William Marsh
IPC分类号： A61M5/315 , A61M5/20 , A61M5/24
CPC分类号： A61M5/31551 , A61M5/20 , A61M5/24 , A61M5/31525 , A61M5/31553 , A61M5/31558 , A61M5/31561 , A61M5/31583 , A61M5/31591 , A61M2005/2086
摘要： The present invention relates to a dispensing speed control mechanism for use in an injection device. The injection device may have a housing (10, 30, 40; 40′; 40″; 40′″) and a drive member (70), which is driven by a power reservoir (100, 100′) and axially movable between a dose setting position, in which the drive member (70) is rotationally constrained to the housing (10, 30, 40; 40′; 40″; 40′″), and a dose dispensing position, in which the drive member (70) is rotationally de-coupled from the housing (10, 30, 40; 40′; 40″; 40′″). The speed control mechanism comprises friction means (42) for retarding the drive member (70) during dose dispensing depending on the axial position of the drive member (70). Further, the invention relates to an injection device with such a dispensing speed control mechanism.

7. 发明申请

US20170266390A1 ADMINISTRATION INSTRUMENT FOR MEDICAL USE 审中-公开
公开(公告)号：US20170266390A1
公开(公告)日：2017-09-21
申请号：US15612328
申请日：2017-06-02
申请人： Panasonic Healthcare Holdings Co., Ltd.
发明人： Tokumi BABA , Tokumi ISHIKAWA , Kouichi MATSUDA
IPC分类号： A61M5/315 , A61M5/46 , A61M5/24 , A61M5/31 , A61M5/32
CPC分类号： A61M5/31596 , A61M5/24 , A61M5/2448 , A61M5/3129 , A61M5/3146 , A61M5/31511 , A61M5/31553 , A61M5/31556 , A61M5/31561 , A61M5/31571 , A61M5/31573 , A61M5/3158 , A61M5/31583 , A61M5/31585 , A61M5/3287 , A61M5/46 , A61M2005/2407 , A61M2005/2488 , A61M2005/2496 , A61M2005/3123 , A61M2005/3125 , A61M2005/3132 , A61M2005/3152 , A61M2205/13 , A61M2205/14 , A61M2205/50 , A61M2205/581 , A61M2205/583
摘要： An administration instrument includes an injection button which can be pressed at an angle that is not parallel to a needle with respect to a direction in which the needle is inserted into skin. As a result, it is possible to prevent a force of pressing the injection button from being transmitted in the direction in which the needle is inserted into the skin deeper than initial insertion of the needle, thereby achieving an administration under a stable state.

8. 发明申请

US20170259006A1 MECHANISM FOR SETTING A MAXIMUM DOSE OF A MEDICAMENT FOR A VARIABLE DOSE DRUG DELIVERY DEVICE 审中-公开
公开(公告)号：US20170259006A1
公开(公告)日：2017-09-14
申请号：US15528623
申请日：2015-11-24
申请人： Sanofi
发明人： Richard James Vincent Avery , Matthew Meredith Jones , William Geoffrey Arthur Marsh , Anthony Paul Morris , David Aubrey Plumptre , Samuel Keir Steel , James Alexander Senior , Robert Frederick Veasey
IPC分类号： A61M5/315 , A61M5/32 , A61M5/24
CPC分类号： A61M5/31538 , A61M5/20 , A61M5/24 , A61M5/31541 , A61M5/31553 , A61M5/31561 , A61M5/3157 , A61M5/31583 , A61M5/31585 , A61M5/329 , A61M2005/3126 , A61M2005/3154 , A61M2205/581 , A61M2205/582 , A61M2205/583
摘要： The present disclosure concerns a mechanism for setting a dose of a medicament for a variable dose drug delivery device, comprising: a housing, a sleeve component configured to rotate relative to the housing during a dose setting operation, and a stop member which is configured to limit a total amount of possible rotation of the sleeve component to a maximum and, thereby, to limit a maximum settable dose, wherein the stop member is configured to allow varying the maximum which determines the total amount of possible rotation of the sleeve component.

9. 发明申请

US20170136190A1 Differential gear mechanism for a drug delivery device and drug delivery device 审中-公开
公开(公告)号：US20170136190A1
公开(公告)日：2017-05-18
申请号：US15310208
申请日：2015-05-27
申请人： Sanofi-Aventis Deutschland GmbH
发明人： Matthew Meredith Jones , Samuel Keir Steel , Neal Alexander Blundred , Joseph Butler , Robert Frederick Veasey , David Plumptre , Anthony Paul Morris
IPC分类号： A61M5/315 , A61M5/32 , A61M5/24
CPC分类号： A61M5/31575 , A61M5/19 , A61M5/2448 , A61M5/31515 , A61M5/31528 , A61M5/31538 , A61M5/31551 , A61M5/31561 , A61M5/31585 , A61M5/31591 , A61M5/31593 , A61M5/31596 , A61M5/3295 , A61M2005/1787 , A61M2005/244 , A61M2005/3126
摘要： The invention is directed to a differential gear mechanism (26) for a drug delivery device with a primary drug delivery assembly (3) and a secondary drug delivery assembly (4), wherein the primary drug delivery assembly (3) comprises a primary dose dial sleeve (17) and wherein the secondary drug delivery assembly (4) comprises a secondary drive sleeve (24). The invention is also directed to a respective drug delivery device.

10. 发明授权

US09457154B2 Injection device with an end of dose feedback mechanism 有权
标题翻译：注射装置结束剂量反馈机制
公开(公告)号：US09457154B2
公开(公告)日：2016-10-04
申请号：US11813389
申请日：2006-01-20
申请人： Claus Schmidt Moller , Bo Radmer , Lars Ulrik Nielsen , Christian Peter Engaard
发明人： Claus Schmidt Moller , Bo Radmer , Lars Ulrik Nielsen , Christian Peter Engaard
IPC分类号： A61M5/315 , A61M5/24 , A61M5/20
CPC分类号： A61M5/3157 , A61M5/20 , A61M5/24 , A61M5/31535 , A61M5/3155 , A61M5/31551 , A61M5/31561 , A61M5/31585 , A61M2205/581 , A61M2205/582
摘要： An injection device with a dose delivering mechanism being adapted to provide a non-visual, e.g. audible and/or tactile, feedback signal when a set dose has been at least substantially injected. A first and a second part of the injection device are adapted to perform a relative rotational movement with respect to each other. The relative rotational movement causes at least two parts of the injection device to abut or engage, and this abutment or engagement causes the non-visual feedback signal to be generated. A very distinct and precise feedback is provided as compared to prior art axial solutions because the generation of the feedback signal is initiated by the relative rotational movement. Feedback signal may be generated by a change in a rotational velocity of at least one part, e.g. by changing the pitch of a threaded portion or by engaging a non-rotating part and a rotating part, thereby causing the non-rotating part to start rotating. May alternatively be generated by building up and releasing a tension. The injection device is suitable for injecting insulin.
摘要翻译：具有剂量递送机构的注射装置适于提供非视觉的，例如，当至少基本上注入了设定的剂量时，可听和/或触觉的反馈信号。注射装置的第一和第二部分适于执行相对于彼此的相对旋转运动。相对旋转运动导致注射装置的至少两个部分邻接或接合，并且该邻接或接合导致产生非视觉反馈信号。与现有技术的轴向解决方案相比，提供了非常独特和精确的反馈，因为反馈信号的产生是由相对旋转运动引起的。反馈信号可以通过至少一个部分的旋转速度的变化来产生，例如，通过改变螺纹部分的间距或通过接合非旋转部分和旋转部分，从而使非旋转部分开始旋转。或者可以通过建立和释放紧张而产生。注射装置适用于注射胰岛素。

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