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    • 1. 发明授权
    • Chamber for freeze-drying by cryosorption
    • 冷冻干燥冷冻室
    • US5438838A
    • 1995-08-08
    • US232151
    • 1994-06-01
    • Hellmuth SitteKlaus NeumannLudwig EdelmannHelmut HaessigHeinrich Kleber
    • Hellmuth SitteKlaus NeumannLudwig EdelmannHelmut HaessigHeinrich Kleber
    • F17C3/08F25D3/10F26B5/06G01N1/28G01N1/42F04B37/08
    • F17C3/085F25D3/10F26B5/06G01N1/42
    • A chamber system for cryosorption freeze-drying of biological specimens in a Dewar vessel, comprises a chamber having a cylindrical metal wall and fitted within the Dewar vessel, a lower outer edge of which chamber is connected in a vacuum-tight manner to a lower edge of a metallic rotational component, the metallic rotational component having a bottom contact surface, which bottom contact surface corresponds with a complementary top contact surface on top of a cylindrical body around which liquid nitrogen flows and cools the metallic rotational component, the rotational component having a chamber to receive a drying agent for conducting cryosorption, for example a molecular screen, as well as a connection to the drying chamber.The upper edge of the metal wall or a ring connected thereto in a vacuum-tight manner is situated outside the Dewar vessel and is therefore approximately at ambient temperature and has a vacuum connection for the connection of commercially available vacuum components. The opening at the top of the ring is preferably sealable in a vacuum-tight manner by a commercially available O-ring in conjunction with a cover.
    • PCT No.PCT / EP93 / 02409 Sec。 371日期1994年6月1日 102(e)1994年6月1日PCT PCT 1993年9月6日PCT公布。 出版物WO94 / 05996 日期:1994年3月17日。用于杜瓦容器中的生物样品冷冻干燥的室系统包括具有圆柱形金属壁并装配在杜瓦容器内的室,其下外边缘在真空中连接 金属旋转部件具有底部接触表面,该底部接触表面对应于液体氮流动的圆筒体顶部的互补顶部接触表面,并且冷却金属旋转部件 旋转部件具有用于接收用于进行低温吸附的干燥剂的室,例如分子筛,以及到干燥室的连接。 金属壁或与真空密封连接的环的上边缘位于杜瓦容器的外部,因此大致处于环境温度并且具有用于连接市售真空部件的真空连接。 环的顶部的开口优选地通过市售的O形环与盖结合而以真空密封的方式密封。