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1. 发明授权

US06422397B1 Blood collection systems including an integral, flexible filter 失效
标题翻译：采血系统包括一体化的柔性过滤器
公开(公告)号：US06422397B1
公开(公告)日：2002-07-23
申请号：US09593782
申请日：2000-06-14
申请人： Daniel R Lynn , Julian P Breillatt, Jr. , John C Burnham
发明人： Daniel R Lynn , Julian P Breillatt, Jr. , John C Burnham
IPC分类号： B01D2900
CPC分类号： B01D29/01 , A61M1/0209 , A61M1/0218 , A61M1/0222 , A61M1/0231 , A61M1/3633 , A61M1/3636 , A61M1/3652 , A61M2202/0439 , B01D29/012 , B01D29/58 , B01D29/908 , B01D39/1623 , B01D39/18 , B01D39/2017 , B01D2239/0622 , B01D2239/0627 , B01D2239/065 , B01D2239/0668 , B01D2239/1216 , B29C65/04 , B29C66/1122 , B29C66/53262 , B29C66/71 , B29C66/723 , B29C66/8322 , B29C66/83221 , B29C66/92651 , B29C66/929 , B29C66/949 , B29K2023/06 , B29K2027/06 , B29L2009/00 , B29L2031/14 , B29L2031/7148 , A61M2202/0057 , B29K2077/00 , B29K2067/00 , B29K2023/12 , B29K2023/00
摘要： Blood collection systems include an integral flexible filter to remove leukocytes from blood components.
摘要翻译：血液收集系统包括一个整体的柔性过滤器，以从血液成分中除去白细胞。

2. 发明授权

US5167656A Blood container having lay-flat sample reservoir 失效
标题翻译：具有平板样品储存器的血液容器
公开(公告)号：US5167656A
公开(公告)日：1992-12-01
申请号：US644177
申请日：1991-01-22
申请人： Daniel R. Lynn
发明人： Daniel R. Lynn
IPC分类号： A61J1/05 , A61J1/10 , A61J1/12 , A61J1/14 , A61M1/02 , A61M5/168 , A61M39/22
CPC分类号： A61M1/0209 , A61J1/12 , A61M2039/222 , Y10T137/4673
摘要： The method is provided of collecting blood with a donor needle inserted into the vein, which comprises an improvement of: after drawing a desired amount of blood into the blood storage container connected to one end of flexible tubing, occluding flow through said flexible tubing at a point adjacent a flexible, transversely enlarged tubing portion positioned at a location on the tubing spaced from the ends. The flow occluding point is located between the enlarged tubing portion and the container, and the tubing portion is initially of lay-flat type, prior to passing blood through it. One then draws more blood through the needle to enter and fill the enlarged tubing portion. One then occludes flexible tubing between the enlarged tubing portion and the needle prior to withdrawing the needle from the vein of the blood donor.
摘要翻译：提供了用插入静脉中的供体针收集血液的方法，其包括以下改进：在将所需量的血液抽吸到连接到柔性管的一端的血液存储容器中之后，阻止通过所述柔性管的流动点位于位于管道上与位于端部间隔开的位置处的柔性的，横向扩大的管部分。流动阻塞点位于扩大的管道部分和容器之间，并且在将血液通过之前，管道部分最初是平面型的。然后，通过针吸入更多的血液以进入和填充扩大的管部分。然后在从供血者的静脉取出针之前，在扩大的管部分和针之间封闭柔性管。

3. 发明授权

US06032807A Methods for correlating average fiber diameter with performance in complex filtration media 失效
标题翻译：将平均纤维直径与复杂过滤介质性能相关联的方法
公开(公告)号：US06032807A
公开(公告)日：2000-03-07
申请号：US697270
申请日：1996-08-21
申请人： Shmuel Sternberg , Daniel R. Lynn
发明人： Shmuel Sternberg , Daniel R. Lynn
IPC分类号： A61M1/34 , A61K35/14 , A61K35/18 , A61M1/02 , A61M1/36 , B01D29/01 , B01D35/02 , B01D39/08 , B01D39/16 , B01D39/18 , B01D39/20 , B01D24/10
CPC分类号： B01D39/2017 , A61M1/0222 , A61M1/3636 , A61M1/3652 , B01D29/012 , B01D39/083 , B01D39/1623 , B01D39/18 , A61M2202/0439 , B01D2239/0471 , B01D2239/0618 , B01D2239/065 , B01D2239/0654 , B01D2239/1233 , Y10S264/26 , Y10S264/48
摘要： A method correlates average fiber diameter with performance for a complex filtration media comprising a matrix of fibers having a fibrillated component with a diameter so small (e.g., less than 0.01 microns), that cannot be physically measured with accuracy. The method manufactures a selected matrix, derives the number average diameter of the fibers according to prescribed steps, some of which do not require actual physical measurements, and observes a performance characteristic. The method repeats the foregoing steps for different matrixes, yielding different number average diameters. The method expresses change in the selected performance characteristic as a function of change in number average diameter of the matrices.
摘要翻译：一种方法将平均纤维直径与复合过滤介质的性能相关联，所述复合过滤介质包含具有直径如此小（例如小于0.01微米）的原纤化组分的纤维基质，其不能精确地物理测量。该方法制造所选择的矩阵，根据规定的步骤导出纤维的数均直径，其中一些不需要实际物理测量，并观察性能特征。该方法针对不同的矩阵重复上述步骤，产生不同的数目平均直径。该方法表示所选择的性能特征的变化作为矩阵的数均直径变化的函数。

4. 发明授权

US5772880A Container with a tangential port 失效
标题翻译：带切向端口的集装箱
公开(公告)号：US5772880A
公开(公告)日：1998-06-30
申请号：US700239
申请日：1996-08-20
申请人： Daniel R. Lynn , Billy W. Minshall , Allen R. Wons , David P. Fisher
发明人： Daniel R. Lynn , Billy W. Minshall , Allen R. Wons , David P. Fisher
IPC分类号： A61M1/34 , A61J1/05 , A61J1/10 , A61K35/14 , A61M1/02 , A61M1/36 , B01D29/00 , B01D29/01 , B01D39/08 , B01D39/16 , B29C65/00 , B29C65/04 , B29C69/00 , B29D22/00 , B29L22/00 , B01D27/08
CPC分类号： B29C66/63 , A61J1/10 , A61M1/0222 , A61M1/3636 , B01D29/012 , B01D39/083 , B01D39/1623 , B29C65/04 , B29C65/08 , B29C66/53246 , B29C66/53262 , B29C66/54 , B29C66/73921 , B29C66/8322 , B29C66/83221 , A61J1/1475 , A61M2202/0439 , B01D2239/0471 , B01D2239/0478 , B01D2239/065 , B01D2239/0654 , B01D2239/0659 , B01D2239/0668 , B01D2239/1216 , B01D2239/1233 , B29C66/541 , B29L2031/7148 , B29L2031/753
摘要： A container has first and second walls, each formed of a thermoplastic sheet having a peripheral edge. A peripheral seal joins the peripheral edges together to form an interior chamber enclosed by the first and second walls. A port communicates with the interior chamber. The port is spaced from and does not extend through the peripheral seal. The port comprises a hollow thermoplastic tube, which extends through a slit in one of the first and second sheets and is oriented tangentially thereto. The slit is fused by heat about the tube, forming a heat fused junction. A medical product or a blood filter material can be housed in the interior chamber.
摘要翻译：容器具有第一和第二壁，每个壁由具有周缘的热塑性片形成。周边密封件将周边边缘连接在一起以形成由第一和第二壁围成的内部腔室。一个端口与内部室连通。端口与周边密封件间隔开并且不延伸通过外围密封件。该端口包括中空热塑管，其延伸穿过第一和第二片中的一个中的狭缝并且与其切向定向。狭缝通过围绕管的热量熔合，形成热熔合连接。医疗产品或血液过滤器材料可以容纳在内部室中。

5. 发明授权

US5591337A Apparatus for filtering leukocytes from blood cells 失效
标题翻译：用于从血细胞中过滤白细胞的装置
公开(公告)号：US5591337A
公开(公告)日：1997-01-07
申请号：US178383
申请日：1993-12-22
申请人： Daniel R. Lynn , Billy W. Minshall , Allen R. Wons , David P. Fisher
发明人： Daniel R. Lynn , Billy W. Minshall , Allen R. Wons , David P. Fisher
IPC分类号： A61M1/34 , A61J1/05 , A61J1/10 , A61K35/14 , A61M1/02 , A61M1/36 , B01D29/00 , B01D29/01 , B01D39/08 , B01D39/16 , B29C65/00 , B29C65/04 , B29C69/00 , B29D22/00 , B29L22/00 , B01D29/56 , B01D29/58 , B32B31/20
CPC分类号： B29C66/63 , A61J1/10 , A61M1/0222 , A61M1/3636 , B01D29/012 , B01D39/083 , B01D39/1623 , B29C65/04 , B29C65/08 , B29C66/53246 , B29C66/53262 , B29C66/54 , B29C66/73921 , B29C66/8322 , B29C66/83221 , A61J1/1475 , A61M2202/0439 , B01D2239/0471 , B01D2239/0478 , B01D2239/065 , B01D2239/0654 , B01D2239/0659 , B01D2239/0668 , B01D2239/1216 , B01D2239/1233 , B29C66/541 , B29L2031/7148 , B29L2031/753
摘要： A blood filtration device encapsulates a filter pad assembly Within a flexible housing. The filter pad assembly includes first and second filter media layers. A first heat and pressure sealed region integrally bonds the peripheries of the first and second media layers together. The flexible housing comprises a peripheral rim aligned with the first heat and pressure sealed region of the first media layer. A second heat and pressure sealed region, formed after the first heat and pressure sealed region, joins the rim of the flexible housing to the first heat and pressure sealed region, thereby forming a composite seal that encapsulates the filter pad assembly within the housing.
摘要翻译：血液过滤装置将过滤垫组件封装在柔性壳体内。过滤垫组件包括第一和第二过滤介质层。第一加热和压力密封区域将第一和第二介质层的周边整体地结合在一起。柔性壳体包括与第一介质层的第一加热和密封区域对准的外围边缘。在第一加热和压力密封区域之后形成的第二加热和加压密封区域将柔性壳体的边缘连接到第一加热和加压密封区域，由此形成将过滤垫组件封装在壳体内的复合密封件。

6. 发明申请

US20090198196A1 PHLEBOTOMY NEEDLE ASSEMBLY AND FRANGIBLE COVER 有权
标题翻译： PHLEBOTOMY针组件和可变盖
公开(公告)号：US20090198196A1
公开(公告)日：2009-08-06
申请号：US12013844
申请日：2008-01-14
申请人： Richard L. West , Daniel R. Lynn , Mark B. Jones , Daniel F. Bischof
发明人： Richard L. West , Daniel R. Lynn , Mark B. Jones , Daniel F. Bischof
IPC分类号： A61M5/00
CPC分类号： A61B5/150541 , A61B5/1405 , A61B5/15003 , A61B5/150259 , A61B5/150366 , A61B5/150389 , A61B5/150519 , A61B5/150549 , A61B5/150587 , A61B5/150595 , A61B5/150618 , A61B5/150717 , A61B5/153 , A61M5/3202 , A61M2005/312
摘要： Medical needle assemblies incorporating a needle cover are provided. According to one aspect, the needle cover is integrally formed from a material that: (1) is sufficiently rigid to prevent bending of an underlying cannula, (2) is suitable for allowing a frangible portion thereof to be broken under pre-selected conditions, and/or (3) has a moisture vapor transmission rate sufficient for steam sterilization of a needle tip enclosed by the needle cover. According to another aspect, at least part of a cap portion and a hub portion of the needle cover are translucent. According to yet another aspect, the needle cover is provided with a wing having an enlarged rib suitable for gripping during separation of a cap portion from the remainder of the needle cover.
摘要翻译：提供了包括针盖的医用针组件。根据一个方面，针盖由以下材料整体形成：（1）足够刚性以防止下面的套管弯曲，（2）适合于允许其易碎部分在预先选定的条件下破裂，和/或（3）具有足够用于由针盖包围的针尖的蒸汽灭菌的水蒸汽透过率。根据另一方面，针罩的帽部和轮毂部的至少一部分是半透明的。根据另一方面，针盖设置有翼，其具有适于在帽部分与针盖的其余部分分离期间抓握的扩大的肋。

7. 发明授权

US07353956B2 Blood collection systems including a flexible filter 失效
标题翻译：采血系统包括一个灵活的过滤器
公开(公告)号：US07353956B2
公开(公告)日：2008-04-08
申请号：US10761850
申请日：2004-01-21
申请人： Daniel R Lynn , Julian P Breillatt, Jr. , John C Burnham , David B. Howard , Allen R Wons
发明人： Daniel R Lynn , Julian P Breillatt, Jr. , John C Burnham , David B. Howard , Allen R Wons
IPC分类号： B01D29/56 , B01D29/58
CPC分类号： B01D29/01 , A61M1/0209 , A61M1/0218 , A61M1/0222 , A61M1/0231 , A61M1/3633 , A61M1/3636 , A61M1/3652 , A61M2202/0439 , B01D29/012 , B01D29/58 , B01D29/908 , B01D39/1623 , B01D39/18 , B01D39/2017 , B01D2239/0622 , B01D2239/0627 , B01D2239/065 , B01D2239/0668 , B01D2239/1216 , B29C65/04 , B29C66/1122 , B29C66/53262 , B29C66/71 , B29C66/723 , B29C66/8322 , B29C66/83221 , B29C66/92651 , B29C66/929 , B29C66/949 , B29K2023/06 , B29K2027/06 , B29L2009/00 , B29L2031/14 , B29L2031/7148 , A61M2202/0057 , B29K2077/00 , B29K2067/00 , B29K2023/12 , B29K2023/00
摘要： Blood collection systems include an integral flexible filter to remove leukocytes from blood components.
摘要翻译：血液收集系统包括一个整体的柔性过滤器，以从血液成分中除去白细胞。

8. 发明授权

US06688476B2 Filter assembly having a flexible housing and method of making same 失效
标题翻译：具有柔性外壳的过滤器组件及其制造方法
公开(公告)号：US06688476B2
公开(公告)日：2004-02-10
申请号：US10084605
申请日：2002-02-27
申请人： Julian P Breillatt, Jr. , John C Burnham , Allen R Wons , Randy Murphy , Daryl R Calhoun , Daniel R Lynn
发明人： Julian P Breillatt, Jr. , John C Burnham , Allen R Wons , Randy Murphy , Daryl R Calhoun , Daniel R Lynn
IPC分类号： B01D2708
CPC分类号： A61M1/3652 , A61M1/0222 , A61M1/0231 , A61M1/3633 , A61M1/3636 , A61M2202/0439 , B01D29/012 , B01D29/58 , B01D29/908 , B01D39/1623 , B01D39/18 , B01D39/2017 , B01D2239/065 , B01D2239/0654 , B01D2239/0668 , B01D2239/10 , B29C45/00 , B29C65/04 , B29C66/1312 , B29C66/30341 , B29C66/5412 , B29C66/71 , B29C66/729 , B29C2793/0009 , B29K2027/06 , B29K2313/00 , B29L2031/14 , B29L2031/753 , A61M2202/0057 , B29K2033/08 , B29K2023/12 , B29K2023/00
摘要： A fluid filter assembly for filtering fluids such as blood is described. The assembly includes first and second filter housing elements formed by an injection molding process. Each element is flexible and includes a peripheral flange formed thereabout and a fluid communicating port formed therein. Filter media, such as a filter membrane, is sealed between the mating flanges of two elements. The fluid filter assembly is capable of collapsing and expanding during the filtration process depending upon the composition of the fluid passed there through. A method for making the filter assembly and systems for using the filter assembly are also disclosed.
摘要翻译：描述了用于过滤诸如血液的流体的流体过滤器组件。组件包括通过注射成型工艺形成的第一和第二过滤器壳体元件。每个元件是柔性的，并且包括在其周围形成的周边凸缘和形成在其中的流体连通口。诸如滤膜之类的过滤介质被密封在两个元件的配合凸缘之间。流体过滤器组件能够在过滤过程中根据通过的流体的组成而塌缩和膨胀。还公开了用于制造过滤器组件的方法和用于使用过滤器组件的系统。

9. 发明授权

US06367634B1 Blood collection systems including an integral, flexible filter 有权
公开(公告)号：US06367634B1
公开(公告)日：2002-04-09
申请号：US09498085
申请日：2000-02-04
申请人： Daniel R. Lynn , Julian P. Breillatt, Jr. , John Burnham
发明人： Daniel R. Lynn , Julian P. Breillatt, Jr. , John Burnham
IPC分类号： B01D2956
CPC分类号： B01D29/012 , A61M1/0222 , A61M1/0231 , A61M1/3636 , A61M1/3652 , A61M2202/0439 , B01D29/58 , B01D29/908 , B01D39/1623 , B01D39/18 , B01D39/2017 , B01D2239/0622 , B01D2239/0627 , B01D2239/065 , B01D2239/0668 , B01D2239/1216 , B29C65/04 , B29C66/1122 , B29C66/53262 , B29C66/71 , B29C66/723 , B29C66/72341 , B29C66/8322 , B29C66/83221 , B29C66/92651 , B29C66/929 , B29C66/949 , B29L2009/00 , B29L2031/14 , B29L2031/7148 , A61M2202/0057 , B29K2023/12 , B29K2027/06 , B29K2067/00 , B29K2077/00
摘要： Blood collection systems include an integral flexible filter to remove leukocytes from blood components.

10. 发明授权

US08323251B2 Phlebotomy needle assembly and frangible cover 有权
标题翻译：断针针组装和易碎盖
公开(公告)号：US08323251B2
公开(公告)日：2012-12-04
申请号：US12013844
申请日：2008-01-14
申请人： Richard L. West , Daniel R. Lynn , Mark B. Jones , Daniel F. Bischof
发明人： Richard L. West , Daniel R. Lynn , Mark B. Jones , Daniel F. Bischof
IPC分类号： A61M5/32 , B65D85/46
CPC分类号： A61B5/150541 , A61B5/1405 , A61B5/15003 , A61B5/150259 , A61B5/150366 , A61B5/150389 , A61B5/150519 , A61B5/150549 , A61B5/150587 , A61B5/150595 , A61B5/150618 , A61B5/150717 , A61B5/153 , A61M5/3202 , A61M2005/312
摘要： Needle covers are provided for medical needle assemblies having a base and a cannula. The needle cover includes hub and cap portions. The hub portion is adapted to be secured to the base. The cap portion is adapted to substantially enclose at least a distal end of the cannula when the hub portion is secured to the base. The cap portion includes at least one generally outwardly extending wing having an outer edge and an enlarged rib extending along only a portion of the outer edge of the wing and only in a direction substantially parallel to a central axis defined by the cap portion. The cap portion is separable from the hub portion upon application of a torsional force, with the rib of the wing being thicker than the portion of the wing radially inward of the outer edge to assist gripping during application of such force.
摘要翻译：为具有底座和插管的医疗针组件提供针盖。针盖包括轮毂和盖部分。轮毂部分适于固定在基座上。当毂部分固定到基座时，帽部分适于基本上包围套管的至少远端。盖部分包括至少一个大致向外延伸的翼，其具有外缘和仅沿着翼的外边缘的一部分延伸的扩大肋，并且仅在基本上平行于由帽部限定的中心轴线的方向上。当施加扭转力时，帽部分可以与轮毂部分分离，翼的肋比外缘的径向内侧的翼的部分更厚，以在施加这种力的同时辅助夹持。

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