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1. 发明申请

US20170232163A1 BLOOD BAG SYSTEM AND PROCESS FOR THE INACTIVATION OF PATHOGENS IN PLATELET CONCENTRATES BY USE OF THE BLOOD BAG SYSTEM 审中-公开
公开(公告)号：US20170232163A1
公开(公告)日：2017-08-17
申请号：US15450375
申请日：2017-03-06
申请人： MACO PHARMA S.A.
发明人： Wolfram Hubert Walker , Frank Tolksdorf , Thierry Verpoort , Francis Goudaliez
IPC分类号： A61M1/02 , A61L2/00 , B65B55/16 , B65B55/08 , A61M1/36 , B65B7/02
CPC分类号： A61M1/0272 , A61J1/10 , A61J1/12 , A61K41/0019 , A61L2/0011 , A61L2/0047 , A61L2202/22 , A61L2202/23 , A61M1/0209 , A61M1/0222 , A61M1/0231 , A61M1/3681 , A61M2205/053 , A61M2205/75 , A61M2207/00 , B65B7/02 , B65B55/08 , B65B55/16
摘要： The present invention relates to a blood bag system, a method for its manufacture, and a process for reducing pathogens and leucocytes in biological fluids in particular in therapeutic quantities of platelet concentrates (PC) contained in the blood bag system, using UV-light and agitation, wherein part of the plasma of the PC is optionally exchanged against a platelet additive solution.

2. 发明授权

US08875893B2 Medical containers for use in blood collection and processing and medical systems, methods and apparatus for use in blood collection and processing 有权
标题翻译：用于血液收集和处理的医疗容器和医疗系统，用于采血和加工的方法和装置
公开(公告)号：US08875893B2
公开(公告)日：2014-11-04
申请号：US13021310
申请日：2011-02-04
申请人： Kyungyoon Min
发明人： Kyungyoon Min
IPC分类号： B65D69/00 , B65D71/00 , A61J1/10 , A61M1/02 , A61M1/36
CPC分类号： A61J1/10 , A61M1/0209 , A61M1/0222 , A61M1/3693 , A61M2205/6072
摘要： Medical containers for use in blood collection and processing and medical systems, methods and apparatus for use in blood collection and processing are described. An example medical container to be used during blood collection and processing, the medical container includes an elongated body defining a compartment and a base coupled at a first end of the elongated body. Additionally, the medical container includes a divider extending through the compartment to separate the compartment into a first subcompartment and a second subcompartment, the divider comprising a first material and the elongated body comprising a second material, the first material being relatively more rigid than the second material, the first subcompartment and the subsecond compartment each to accommodate blood pack components.
摘要翻译：描述了用于血液收集和处理的医疗容器以及用于采血和处理的医疗系统，方法和装置。在血液收集和处理期间使用的示例性医疗容器，医疗容器包括限定隔室的细长主体和在细长主体的第一端处联接的基部。另外，医疗容器包括延伸穿过隔室的分隔件，以将隔室分隔成第一子隔室和第二子隔室，分隔件包括第一材料，细长主体包括第二材料，第一材料比第二材料相对更刚性材料，第一个子舱和第二个舱室，每个舱室适合血液包装组件。

3. 发明授权

US08057670B2 Biological fluid filtration system and biological filter used therein 失效
标题翻译：生物流体过滤系统及其中使用的生物过滤器
公开(公告)号：US08057670B2
公开(公告)日：2011-11-15
申请号：US13048126
申请日：2011-03-15
申请人： Majid Zia , Chaouki A. Khamis
发明人： Majid Zia , Chaouki A. Khamis
IPC分类号： B01D36/00
CPC分类号： A61M1/0209 , A61M1/0218 , A61M1/0222 , A61M1/0231 , A61M1/3633
摘要： A biological fluid processing or fluid filtration system is provided having novel open and closed loop processing systems wherein the gases transferred into and out of the system during processing pass through a porous medium in upstream and/or downstream gas inlet or outlet housings or vents in a manner which precludes the fluid being processed or filtered from ever contacting the housings or vents. Each housing or vent is separated from the fluid by a column of gas in its respective transfer line. The upstream gas inlet housing or vent is in communication with the unfiltered biological fluid, and the downstream gas inlet housing or vent is in communication with the filtered biological fluid.
摘要翻译：提供了具有新颖的开放和闭环处理系统的生物流体处理或流体过滤系统，其中在处理过程中传入和输出系统的气体通过上游和/或下游气体入口或出口壳体或通风口中的多孔介质排除流体被处理或过滤的方式不断接触壳体或通风口。每个壳体或通风孔在其各自传输线中通过一列气体与流体分离。上游气体入口壳体或通气口与未过滤的生物流体连通，并且下游气体入口壳体或通气口与经过滤的生物流体连通。

4. 发明授权

US07993531B2 Biological fluid filtration systems and methods 有权
标题翻译：生物流体过滤系统及方法
公开(公告)号：US07993531B2
公开(公告)日：2011-08-09
申请号：US12098876
申请日：2008-04-07
申请人： Anthony Oleszkiewicz , Bryan Blickhan , Mark B. Jones
发明人： Anthony Oleszkiewicz , Bryan Blickhan , Mark B. Jones
IPC分类号： B01D37/00 , B01D29/00
CPC分类号： A61M1/3633 , A61M1/0209 , A61M1/0222 , A61M1/0231
摘要： Biological fluid filtration methods are provided for the treatment of gas within a biological fluid filtration system. A quantity of biological fluid is flowed under the force of gravity through a leukocyte removal filter and into a post-filter container. The post-filter container has a maximum vented volume that is approximately the same as the quantity of biological fluid flowed through the filter and into the post-filter container. At least a substantial portion of the gas in the post-filter container is vented therefrom without separately restricting expansion of the post-filter container and without manually manipulating the post-filter container to expel gas.
摘要翻译：提供生物流体过滤方法用于在生物流体过滤系统内处理气体。一定数量的生物流体在重力作用下通过白细胞去除过滤器流入后过滤容器中。后过滤容器具有与流过过滤器并进入后过滤容器的生物流体的量大致相同的最大排气量。后过滤容器中的至少大部分气体从其排放而不分开限制后过滤容器的膨胀，而不需要手动操作后过滤容器排出气体。

5. 发明申请

US20100222702A1 METHOD OF USING A PACKAGING MATERIAL FOR A MEDICAL INSTRUMENT SET 审中-公开
标题翻译：使用包装材料用于医用仪器的方法
公开(公告)号：US20100222702A1
公开(公告)日：2010-09-02
申请号：US12779714
申请日：2010-05-13
申请人： Tadashi IMAI
发明人： Tadashi IMAI
IPC分类号： B67B7/00 , A61B5/15
CPC分类号： A61M1/0218 , A61J1/16 , A61M1/0222 , A61M2209/06
摘要： A method for using a packaging material for a medical instrument set, the medical instrument set being housed in said packaging material and assembled from a plurality of medical instruments. The packaging material includes a packaging material body having an opening therein and a lid that closes the opening and holds or fastens, on an inside portion thereof, a blood collecting needle. The method includes an opening operation for peeling off the lid to expose the opening to an outside environment while letting the blood collecting needle through the opening, and then taking the blood collecting needle out from the packaging material body; a preparation operation for removing the blood collecting needle from the lid; and a blood collecting operation for collecting blood by using the blood collecting needle in a stage where the blood-processing part is housed in the packaging material body.
摘要翻译：一种用于医疗器械组的包装材料的方法，所述医疗器械组被容纳在所述包装材料中并由多个医疗器械组装。包装材料包括其中具有开口的包装材料主体和封闭开口并在其内侧部分收集或紧固血液收集针的盖。该方法包括打开操作，用于剥离盖子，使开口暴露于外部环境，同时使采血针通过开口，然后将采集针从包装材料体中取出; 用于从所述盖移除所述采集针的准备操作; 以及采血操作，用于在血液处理部被容纳在包装材料体中的阶段中通过使用采血针收集血液。

6. 发明授权

US07686797B2 Biological fluid filtration system utilizing by-pass line and tube support device 有权
标题翻译：生物流体过滤系统利用旁路线管支撑装置
公开(公告)号：US07686797B2
公开(公告)日：2010-03-30
申请号：US11395662
申请日：2006-03-31
申请人： Majid Zia , Anthony J. Angelo , Craig M. Wilson
发明人： Majid Zia , Anthony J. Angelo , Craig M. Wilson
IPC分类号： A61B19/00
CPC分类号： A61M5/1418 , A61M1/0222 , A61M39/08 , A61M2202/0439 , A61M2209/08 , A61M2202/005
摘要： An improved biological fluid filtration system is shown having, seriatim, a blood container, a biological fluid filtration device downstream of the blood container, and a blood receiving container downstream of the biological fluid filtration device; a bypass line is provided to allow fluid communication between the blood container and the blood receiving container, the bypass line includes a loop, the loop of the bypass line being configured to be disposed above the blood container at a sufficient height to prevent the passage of fluid around the leukocyte depletion device; the loop of the bypass line being disposed in a tube support device, the tube support device being configured to support substantially the entire weight of the biological fluid filtration system without substantially crimping said bypass line.
摘要翻译：显示了一种改进的生物流体过滤系统，其在血液容器的下游具有血管容器，生物流体过滤装置和生物流体过滤装置下游的血液接收容器，提供旁通管线以允许血液容器和血液接收容器之间的流体连通，旁路管线包括环路，旁路管线的环路被配置为以足够的高度设置在血液容器上方，以防止通过白细胞耗尽装置周围的液体; 旁路管路的环路设置在管支撑装置中，管支撑装置被配置为基本上支撑生物流体过滤系统的整个重量，而基本上不压缩所述旁路管线。

7. 发明授权

US07571744B2 Multi-purpose tubing apparatus 失效
公开(公告)号：US07571744B2
公开(公告)日：2009-08-11
申请号：US10066515
申请日：2002-01-31
申请人： Majid Zia , Anthony J. Angelo , Craig M. Wilson
发明人： Majid Zia , Anthony J. Angelo , Craig M. Wilson
IPC分类号： F16L3/00
CPC分类号： A61M5/1418 , A61M1/0222 , A61M39/08 , A61M2202/0439 , A61M2209/08 , A61M2202/005
摘要： An improved tubing device, preferably for use in the medical industry is provided. The tubing device provides a seamless transport path by using the tubing itself as the transport means without any other internally wetted parts, or connections, to provide a substantial reduction in the number of fluid contact components, and eliminate the need for cutting tubes into segments to be later bonded via tubing connectors. This can reduce the risk of contamination of the transported materials and can also reduce the use of chemicals such as adhesives and bonding agents.

8. 发明授权

US07569026B2 Method of producing blood processing circuits and filter unit 有权
标题翻译：生产血液处理电路和过滤器的方法
公开(公告)号：US07569026B2
公开(公告)日：2009-08-04
申请号：US10574201
申请日：2004-09-29
申请人： Hiroyuki Sugawara
发明人： Hiroyuki Sugawara
IPC分类号： A61M37/00 , A61M1/00 , A61B19/00
CPC分类号： A61M1/3633 , A61M1/0222 , A61M1/0231 , A61M39/16
摘要： A bag connection comprises a first bag, a tube having a blood-drawing needle at the front end, a plurality of second bags, tubes for connecting the first and second bags, and tubes and branch connectors for connecting the second bags to each other. On the other hand, a filter unit includes a filter, and a tube connected at opposite ends thereof to the inlet and outlet of the filter. The tubes of the bag concatenation and the tube of the filter unit have respective markers attached thereto. With these markers used as marks, both tubes are aseptically connected by a tube aseptic connection device, thereby incorporating the filter unit into an intermediate portion of a tube of the bag concatenation.
摘要翻译：袋连接包括第一袋，在前端具有抽血针的管，多个第二袋，用于连接第一袋和第二袋的管，以及用于将第二袋彼此连接的管和分支连接器。另一方面，过滤器单元包括过滤器和在其相对端连接到过滤器的入口和出口的管。袋子级联的管和过滤器单元的管具有附接到其上的各自的标记。使用这些标记作为标记，两个管通过管无菌连接装置无菌连接，从而将过滤器单元并入袋连接管的中间部分。

9. 发明申请

US20090173685A1 BLOOD TREATMENT FILTER AND BLOOD TREATMENT CIRCUIT 审中-公开
标题翻译：血液处理过滤器和血液治疗电路
公开(公告)号：US20090173685A1
公开(公告)日：2009-07-09
申请号：US12305076
申请日：2007-06-15
申请人： Tadashi Imai , Junichi Ohkawara , Masahide Murakoshi
发明人： Tadashi Imai , Junichi Ohkawara , Masahide Murakoshi
IPC分类号： B01D35/30 , B01D35/06 , B01D35/02
CPC分类号： A61M1/0222 , A61M1/0231 , A61M1/0236 , A61M1/3633
摘要： A blood treatment filter which comprises a housing including an inlet and an outlet, and a filter unit for filtering blood containing erythrocytes, platelets and leukocytes as blood cell components is provided.The filter unit comprises a main filter unit which virtually removes predetermined cell components from blood and passes the remaining blood cell components, and a pre-filter unit which is arranged at the up-stream side of the main filter and virtually does not remove blood cell components.The pre-filter unit has a permeability rate of 70 to 90% for micro particles having an average particle size of 6 μm which are contained in a suspension and passed by gravity.
摘要翻译：一种血液处理过滤器，其特征在于，具备包括入口和出口的壳体，以及用于过滤血液的过滤器单元，所述过滤器单元用于过滤含血红细胞，血小板和白细胞的血液作为血细胞成分。过滤器单元包括主过滤器单元，其主要从血液中去除预定的细胞成分并使剩余的血细胞成分通过;以及预过滤器单元，其布置在主过滤器的上游侧并且实质上不除血细胞组件。预过滤器单元对悬浮液中含有的平均粒径为6μm的微粒子的重力渗透率为70〜90％。

10. 发明申请

US20080156728A1 BIOLOGICAL FLUID FILTRATION SYSTEMS AND METHODS 审中-公开
标题翻译：生物流体过滤系统和方法
公开(公告)号：US20080156728A1
公开(公告)日：2008-07-03
申请号：US11618286
申请日：2006-12-29
申请人： Bryan Blickhan , Anthony Oleszkiewicz
发明人： Bryan Blickhan , Anthony Oleszkiewicz
IPC分类号： A61M1/34 , B01D61/14
CPC分类号： A61M1/3633 , A61M1/0209 , A61M1/0222 , A61M1/0231
摘要： Biological fluid filtration systems and methods are provided for the treatment of air within the system. A filtration system includes a pre-filter container joined to an expandable post-filter container by a filter line having a filter. The post-filter container includes a volume restriction that limits its expansion upon receipt of a filtered fluid. In use, a fluid is transferred from the pre-filter container, through the filter line and the filter, to the post-filter container. The volume restriction limits the expansion of the post-filter container during filtration, which increases the pressure within the post-filter container, thereby improving removal of air from the post-filter container.
摘要翻译：提供生物流体过滤系统和方法来处理系统内的空气。过滤系统包括通过具有过滤器的过滤管线连接到可膨胀后过滤容器的预过滤器容器。后过滤容器包括限制其在接收过滤流体时的膨胀的体积限制。在使用中，流体从预过滤器容器通过过滤器管线和过滤器传送到后过滤容器。容积限制限制过滤器过滤容器的膨胀，这增加了后过滤容器内的压力，从而改善了从后过滤容器中除去空气。

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