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1. 发明授权

US08577460B2 Acoustically powered implantable stimulating device 有权
公开(公告)号：US08577460B2
公开(公告)日：2013-11-05
申请号：US13046083
申请日：2011-03-11
申请人： Avi Penner
发明人： Avi Penner
IPC分类号： A61N1/00
CPC分类号： A61N1/08 , A61B5/0031 , A61B2017/00026 , A61B2560/0219 , A61B2562/028 , A61N1/362 , A61N1/3718 , A61N1/37217 , A61N1/3787 , A61N7/00
摘要： An implantable stimulation system comprises an implantable stimulator and a control device. The control device is configured to transmit acoustic waves to the implantable stimulator, and the implantable stimulator is configured to transform the acoustic waves into electrical current, and generate stimulation energy based on the electrical current. For example, the electrical current can be transformed into electrical energy that can be used to generate the stimulation energy. Or the electrical current can contain signals used to directly or indirectly control the generation of the stimulation energy.

2. 再颁专利

USRE42378E1 Implantable pressure sensors and methods for making and using them 有权
标题翻译：可植入压力传感器及其制造和使用的方法
公开(公告)号：USRE42378E1
公开(公告)日：2011-05-17
申请号：US11491533
申请日：2006-07-20
申请人： Lone Wolinsky , Eyal Doron , Alon Ben-Yoseph , Avi Penner
发明人： Lone Wolinsky , Eyal Doron , Alon Ben-Yoseph , Avi Penner
IPC分类号： A61B5/04
CPC分类号： A61B5/0028 , A61B5/0031 , A61B5/01 , A61B5/0215 , A61B5/031 , A61B5/053 , A61B5/076 , A61B5/14539 , A61B2560/0219 , A61B2562/0247 , A61B2562/028 , A61N1/37217 , A61N1/3787 , A61N5/0601 , A61N5/062 , A61N2005/0651
摘要： An implant includes a pressure sensor, a controller for acquiring pressure data from the sensor, and an acoustic transducer for converting energy between electrical energy and acoustic energy. A capacitor is coupled to the acoustic transducer for storing electrical energy converted by the transducer and/or for providing electrical energy to operate the implant. The acoustic transducer may operate alternatively or simultaneously as an energy exchanger or an acoustic transmitter. During use, the implant is implanted within a patient's body, and an external transducer transmits a first acoustic signal into the patient's body, to energize the capacitor. The implant then obtains pressure data, and transmits a second acoustic signal to the external transducer, the second acoustic signal including the pressure data.
摘要翻译：植入物包括压力传感器，用于从传感器获取压力数据的控制器和用于在电能和声能之间转换能量的声换能器。电容器耦合到声换能器，用于存储由换能器转换的电能和/或用于提供电能以操作植入物。声换能器可以作为能量交换器或声发射器交替地或同时地操作。在使用期间，将植入物植入患者体内，并且外部换能器将第一声信号传送到患者体内，以激励电容器。然后，植入物获得压力数据，并将第二声学信号发送到外部换能器，第二声学信号包括压力数据。

3. 发明授权

US07641619B2 Barometric pressure correction based on remote sources of information 有权
标题翻译：基于远程信息源的气压校正
公开(公告)号：US07641619B2
公开(公告)日：2010-01-05
申请号：US11858085
申请日：2007-09-19
申请人： Avi Penner
发明人： Avi Penner
IPC分类号： A61B5/00
CPC分类号： A61N1/37217 , A61B5/00 , A61B5/0031 , A61B5/02 , A61B5/0215 , A61B5/076 , A61B5/1112 , A61B5/14539 , A61B5/4839 , A61B8/4281 , A61B8/4472 , A61B8/56 , A61B2560/0209 , A61B2560/0214 , A61B2560/0219 , A61B2560/0242 , A61B2560/0257 , A61B2560/0412 , A61B2562/028 , A61N1/08 , A61N1/37235 , A61N1/37252 , A61N1/3787 , Y10S128/903
摘要： The invention includes systems and methods for converting absolute pressure data acquired in anatomical environments to gauge pressure data using an implant configured to monitor pressure. The implant is configured to communicate with an external controller, which is configured to communicate with a remote microprocessor that includes real-time barometric pressure data for one or more geographic locations.
摘要翻译：本发明包括用于将在解剖学环境中获取的绝对压力数据转换为使用构造成监测压力的植入物来测量压力数据的系统和方法。植入物被配置为与外部控制器进行通信，其被配置为与包括用于一个或多个地理位置的实时气压数据的远程微处理器进行通信。

4. 发明申请

US20080103553A1 SYSTEMS AND METHODS FOR COMMUNICATING WITH IMPLANTABLE DEVICES 有权
标题翻译：用于与可移植设备通信的系统和方法
公开(公告)号：US20080103553A1
公开(公告)日：2008-05-01
申请号：US11876620
申请日：2007-10-22
申请人： Avi Penner , Eyal Doron
发明人： Avi Penner , Eyal Doron
IPC分类号： A61N1/08
CPC分类号： A61N1/37217 , A61B5/00 , A61B5/0031 , A61B5/02 , A61B5/0215 , A61B5/076 , A61B5/1112 , A61B5/14539 , A61B5/4839 , A61B8/4281 , A61B8/4472 , A61B8/56 , A61B2560/0209 , A61B2560/0214 , A61B2560/0219 , A61B2560/0242 , A61B2560/0257 , A61B2560/0412 , A61B2562/028 , A61N1/08 , A61N1/37235 , A61N1/37252 , A61N1/3787 , Y10S128/903
摘要： Systems and methods for communicating with an implant within a patient's body using acoustic telemetry includes an external communications device attachable to the patient's skin. The device includes an acoustic transducer for transmitting acoustic signals into the patient's body and/or for receiving acoustic signals from the implant. The device includes a battery for providing electrical energy to operate the device, a processor for extracting data from acoustic signals received from the implant, and memory for storing the data. The device may include an interface for communicating with a recorder or computer, e.g., to transfer data from the implant and/or to receive instructions for controlling the implant. The device is secured to the patient's skin for controlling, monitoring, or otherwise communicating with the implant, while allowing the patient to remain mobile.
摘要翻译：使用声学遥测与患者体内的植入物进行通信的系统和方法包括可附接到患者皮肤的外部通信装置。该装置包括用于将声信号传送到患者体内和/或用于从植入物接收声信号的声换能器。该装置包括用于提供电能以操作装置的电池，用于从从植入物接收的声信号中提取数据的处理器，以及用于存储数据的存储器。该装置可以包括用于与记录器或计算机通信的接口，例如从植入物传送数据和/或接收用于控制植入物的指令。该装置被固定到患者的皮肤上，用于控制，监测或以其他方式与植入物通信，同时允许患者保持移动。

5. 发明授权

US06699186B1 Methods and apparatus for deploying and implantable biosensor 有权
标题翻译：用于部署和植入生物传感器的方法和装置
公开(公告)号：US06699186B1
公开(公告)日：2004-03-02
申请号：US09523414
申请日：2000-03-10
申请人： Lone Wolinsky , Avi Penner
发明人： Lone Wolinsky , Avi Penner
IPC分类号： A61B500
CPC分类号： A61B5/6876 , A61B1/00147 , A61B5/02014 , A61B5/0215 , A61B5/026 , A61B5/076 , A61B5/11 , A61B5/14546 , A61B5/6862
摘要： An implantation device for delivering a biosensor to an implantation site in a patient's body comprises an elongate catheter equipped with a distally located cavity sized to house a biosensor. Once the distal end of the catheter is positioned adjacent the implantation site, the biosensor is released through an opening from the cavity into the site. A removable cover, such as a thin adhesive film, may be used to retain the biosensor in the cavity, while the catheter is guided through the body to the implantation site. The implantation device may include an actuator for displacing the biosensor from the cavity into the implantation site. By way of one example, the actuator may be a piston inserted through a lumen of the catheter.
摘要翻译：用于将生物传感器递送到患者体内的植入部位的植入装置包括：细长导管，其具有设置成容纳生物传感器的位于远侧的腔。一旦导管的远端位于植入位置附近，生物传感器通过从空腔的开口释放到现场。可以使用诸如薄的粘合剂膜的可移除的盖子将生物传感器保持在空腔中，同时导管被引导穿过身体到植入部位。植入装置可以包括用于将生物传感器从腔体移位到植入部位的致动器。作为一个示例，致动器可以是穿过导管的内腔插入的活塞。

6. 发明授权

US06628989B1 Acoustic switch and apparatus and methods for using acoustic switches within a body 有权
标题翻译：声学开关以及在体内使用声学开关的装置和方法
公开(公告)号：US06628989B1
公开(公告)日：2003-09-30
申请号：US09690615
申请日：2000-10-16
申请人： Avi Penner , Eyal Doron
发明人： Avi Penner , Eyal Doron
IPC分类号： A61N1372
CPC分类号： A61N1/3787 , A61B5/0028 , A61B5/0031 , A61B5/01 , A61B5/0215 , A61B5/031 , A61B5/053 , A61B5/076 , A61B5/14539 , A61B2560/0219 , A61B2562/0247 , A61B2562/028 , A61N1/37217 , A61N5/0601 , A61N5/062 , A61N2005/0651
摘要： An implant for insertion or implantation within a body includes an electrical circuit for performing one or more commands when the implant is activated, an energy storage device, and a switch coupled to the electrical circuit and the energy storage device. An acoustic transducer is coupled to the switch, the acoustic transducer being activatable upon acoustic excitation by an external acoustic energy source for closing the switch to allow current flow from the energy storage device to the electrical circuit. The one or more commands includes measuring a physiological parameter with a biosensor coupled to the electrical circuit, or controlling a therapeutic device coupled to the electrical circuit. The therapeutic device or biosensor may be activated for a predetermined time or until the switch is opened in response to another acoustic excitation of the acoustic transducer.
摘要翻译：用于在体内插入或植入的植入物包括用于在植入物被激活时执行一个或多个命令的电路，能量存储装置和耦合到电路和能量存储装置的开关。声换能器耦合到开关，声换能器可在通过用于闭合开关的外部声能源进行声激励时激活，以允许电流从能量存储装置流向电路。一个或多个命令包括使用耦合到电路的生物传感器测量生理参数，或者控制耦合到电路的治疗装置。治疗装置或生物传感器可以被激活预定时间，或者直到响应于声换能器的另一声激发而打开开关。

7. 发明授权

US08540631B2 Apparatus and methods using acoustic telemetry for intrabody communications 有权
标题翻译：使用声学遥测进行体内通讯的装置和方法
公开(公告)号：US08540631B2
公开(公告)日：2013-09-24
申请号：US11680529
申请日：2007-02-28
申请人： Avi Penner , Eyal Doron
发明人： Avi Penner , Eyal Doron
IPC分类号： A61B5/07 , A61B5/02
CPC分类号： A61N1/37217 , A61B5/0008 , A61B5/0028 , A61B5/0031 , A61B5/0215 , A61B5/026 , A61B5/031 , A61B5/14532 , A61B5/14539 , A61B5/4839 , A61B2017/00026 , A61B2560/0214 , A61B2560/0257 , A61M5/14276 , A61M5/1723 , A61M2205/3507 , A61N1/37288 , A61N1/378 , G06F19/00
摘要： Systems and methods provide intrabody communication using acoustic telemetry. The system includes a first or control implant including a first acoustic transducer, and a second implant including a switch and a second acoustic transducer coupled to the switch. The second acoustic transducer receives acoustic signals from the first acoustic transducer for closing the switch to activate the second implant. The second implant may include a sensor for measuring a physiological parameter that is transmitted using acoustic signals including the physiological data to the first implant. For example, the second implant may measure pressure in the patient's heart that may be used by the first implant to control a pacemaker. Alternatively, the second implant may blood sugar concentration that may be used by the first implant to control an insulin pump. Alternatively, the first implant may store and transfer the data to an external device for monitoring the patient.
摘要翻译：系统和方法使用声学遥测提供体内通信。该系统包括包括第一声换能器的第一或控制植入物，以及包括开关和耦合到开关的第二声换能器的第二植入物。第二声换能器接收来自第一声换能器的声信号，用于闭合开关以激活第二植入。第二植入物可以包括用于测量使用包括生理数据的声学信号发送到第一植入物的生理参数的传感器。例如，第二植入物可以测量患者心脏中可能被第一植入物用于控制起搏器的压力。或者，第二植入物可以由第一植入物使用以控制胰岛素泵的血糖浓度。或者，第一植入物可以将数据存储并传送到用于监测患者的外部设备。

8. 发明授权

US07930031B2 Acoustically powered implantable stimulating device 有权
标题翻译：声学动力植入式刺激装置
公开(公告)号：US07930031B2
公开(公告)日：2011-04-19
申请号：US11871017
申请日：2007-10-11
申请人： Avi Penner
发明人： Avi Penner
IPC分类号： A61N1/362
CPC分类号： A61N1/08 , A61B5/0031 , A61B2017/00026 , A61B2560/0219 , A61B2562/028 , A61N1/362 , A61N1/3718 , A61N1/37217 , A61N1/3787 , A61N7/00
摘要： An implantable stimulation system comprises an implantable stimulator and a control device. The control device is configured to transmit acoustic waves to the implantable stimulator, and the implantable stimulator is configured to transform the acoustic waves into electrical current, and generate stimulation energy based on the electrical current. For example, the electrical current can be transformed into electrical energy that can be used to generate the stimulation energy. Or the electrical current can contain signals used to directly or indirectly control the generation of the stimulation energy.
摘要翻译：可植入刺激系统包括可植入刺激器和控制装置。控制装置被配置为将声波传播到可植入刺激器，并且可植入刺激器被配置为将声波转换成电流，并且基于电流产生刺激能量。例如，电流可以转换成可用于产生刺激能量的电能。或者电流可以包含用于直接或间接地控制产生刺激能量的信号。

9. 发明申请

US20070142728A1 APPARATUS AND METHODS USING ACOUSTIC TELEMETRY FOR INTRABODY COMMUNICATIONS 有权
标题翻译：装置和方法使用声学电视进行内部通信
公开(公告)号：US20070142728A1
公开(公告)日：2007-06-21
申请号：US11680529
申请日：2007-02-28
申请人： Avi Penner , Eyal Doron
发明人： Avi Penner , Eyal Doron
IPC分类号： A61B5/02 , A61B5/00
CPC分类号： A61N1/37217 , A61B5/0008 , A61B5/0028 , A61B5/0031 , A61B5/0215 , A61B5/026 , A61B5/031 , A61B5/14532 , A61B5/14539 , A61B5/4839 , A61B2017/00026 , A61B2560/0214 , A61B2560/0257 , A61M5/14276 , A61M5/1723 , A61M2205/3507 , A61N1/37288 , A61N1/378 , G06F19/00
摘要： Systems and methods provide intrabody communication using acoustic telemetry. The system includes a first or control implant including a first acoustic transducer, and a second implant including a switch and a second acoustic transducer coupled to the switch. The second acoustic transducer receives acoustic signals from the first acoustic transducer for closing the switch to activate the second implant. The second implant may include a sensor for measuring a physiological parameter that is transmitted using acoustic signals including the physiological data to the first implant. For example, the second implant may measure pressure in the patient's heart that may be used by the first implant to control a pacemaker. Alternatively, the second implant may blood sugar concentration that may be used by the first implant to control an insulin pump. Alternatively, the first implant may store and transfer the data to an external device for monitoring the patient.
摘要翻译：系统和方法使用声学遥测提供体内通信。该系统包括包括第一声换能器的第一或控制植入物，以及包括开关和耦合到开关的第二声换能器的第二植入物。第二声换能器接收来自第一声换能器的声信号，用于闭合开关以激活第二植入。第二植入物可以包括用于测量使用包括生理数据的声学信号发送到第一植入物的生理参数的传感器。例如，第二植入物可以测量患者心脏中可能被第一植入物用于控制起搏器的压力。或者，第二植入物可以由第一植入物使用以控制胰岛素泵的血糖浓度。或者，第一植入物可以将数据存储并传送到用于监测患者的外部设备。

10. 发明授权

US07198603B2 Apparatus and methods using acoustic telemetry for intrabody communications 有权
标题翻译：使用声学遥测进行体内通讯的装置和方法
公开(公告)号：US07198603B2
公开(公告)日：2007-04-03
申请号：US10413428
申请日：2003-04-14
申请人： Avi Penner , Eyal Doron
发明人： Avi Penner , Eyal Doron
IPC分类号： A61B5/02 , A61N1/00
CPC分类号： A61N1/37217 , A61B5/0008 , A61B5/0028 , A61B5/0031 , A61B5/0215 , A61B5/026 , A61B5/031 , A61B5/14532 , A61B5/14539 , A61B5/4839 , A61B2017/00026 , A61B2560/0214 , A61B2560/0257 , A61M5/14276 , A61M5/1723 , A61M2205/3507 , A61N1/37288 , A61N1/378 , G06F19/00
摘要： Systems and methods provide intrabody communication using acoustic telemetry. The system includes a first or control implant including a first acoustic transducer, and a second implant including a switch and a second acoustic transducer coupled to the switch. The second acoustic transducer receives acoustic signals from the first acoustic transducer for closing the switch to activate the second implant. The second implant may include a sensor for measuring a physiological parameter that is transmitted using acoustic signals including the physiological data to the first implant. For example, the second implant may measure pressure in the patient's heart that may be used by the first implant to control a pacemaker. Alternatively, the second implant may blood sugar concentration that may be used by the first implant to control an insulin pump. Alternatively, the first implant may store and transfer the data to an external device for monitoring the patient.
摘要翻译：系统和方法使用声学遥测提供体内通信。该系统包括包括第一声换能器的第一或控制植入物，以及包括开关和耦合到开关的第二声换能器的第二植入物。第二声换能器接收来自第一声换能器的声信号，用于闭合开关以激活第二植入。第二植入物可以包括用于测量使用包括生理数据的声学信号发送到第一植入物的生理参数的传感器。例如，第二植入物可以测量患者心脏中可能被第一植入物用于控制起搏器的压力。或者，第二植入物可以由第一植入物使用以控制胰岛素泵的血糖浓度。或者，第一植入物可以将数据存储并传送到用于监测患者的外部设备。

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