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1. 发明授权

US12121684B1 Method of treating normal pressure hydrocephalus 有权
公开(公告)号：US12121684B1
公开(公告)日：2024-10-22
申请号：US18227743
申请日：2023-07-28
申请人： Carlos A. Hakim
发明人： Carlos A. Hakim
IPC分类号： A61M27/00 , A61B5/00 , A61B5/03
CPC分类号： A61M27/006 , A61B5/0042 , A61B5/031 , A61B5/032
摘要： A ventricular shunt assembly, used in conjunction with a hyperbaric environment (e.g., having a pressure of about 250 to about 350 mm H2O above atmospheric pressure) can be used to correct a patient's intraparenchymal venous pressure from a sub-normally low value to a normal value. The shunt may comprise a valve, e.g., and adjustable valve, disposed between the ventricular catheter and the distal catheter. Optionally, the shunt comprises a reservoir on the ventricular side of the valve.

2. 发明授权

US12109379B2 System and method for draining cerebrospinal fluid in hydrocephalus patients 有权
公开(公告)号：US12109379B2
公开(公告)日：2024-10-08
申请号：US17889673
申请日：2022-08-17
申请人： Alan Richard Turtz
发明人： Alan Richard Turtz
IPC分类号： A61B5/03 , A61B5/00 , A61M25/00 , A61M27/00 , A61B5/021 , A61B5/024 , A61B5/083
CPC分类号： A61M27/006 , A61B5/0031 , A61B5/031 , A61M25/0068 , A61B5/021 , A61B5/024 , A61B5/0836 , A61B5/4561 , A61M2025/0073 , A61M2202/0464 , A61M2210/0693
摘要： A system and related method are provided for draining cerebrospinal fluid from a bodily cavity of a patient, such as a ventricle in the brain in one application. The system includes a reservoir which may be a collapsible container configured for fluidic connection to a shunt located in the bodily cavity. The collapsible container may be an elastically deformable bladder in one embodiment. A pump is fluidly connected to the collapsible container and draws cerebrospinal fluid therefrom. A programmable controller directs the pump to repeatedly activate and deactivate at a predetermined time interval. A plurality of sensors may be provided which are communicably coupled to the controller for monitoring pump motor current draw, tension in the resilient body of the container, pressure, and orientation of the patient. The controller is configurable to deactivate the pump when abnormal operating conditions are detected by the sensors.

3. 发明授权

US12064259B2 Method and apparatus for measuring flow through a lumen 有权
公开(公告)号：US12064259B2
公开(公告)日：2024-08-20
申请号：US17949103
申请日：2022-09-20
申请人： Alio, Inc.
发明人： David John Kuraguntla , Samit Kumar Gupta , Robert Lawrence Rushenberg
IPC分类号： A61B5/00 , A61B5/0205 , A61B5/0215 , A61B5/026 , A61F2/07 , A61F2/852 , A61B5/03 , A61B5/20 , A61F2/06 , A61F2/48
CPC分类号： A61B5/4851 , A61B5/002 , A61B5/0022 , A61B5/0031 , A61B5/02055 , A61B5/0215 , A61B5/026 , A61B5/6862 , A61B5/742 , A61F2/07 , A61F2/852 , A61B5/031 , A61B5/20 , A61B2560/0214 , A61F2/06 , A61F2002/075 , A61F2/482 , A61F2250/0002
摘要： A prosthesis for monitoring a characteristic of flow includes a first tubular prosthesis having a lumen and a sensor for detecting the characteristic of flow through the lumen. The sensor may be covered with another tubular prosthesis or by a layer of material in order to insulate the sensor from the fluid flow. A pocket may be formed between the tubular prosthesis and the adjacent layer of material or prosthesis and the sensor may be disposed in the pocket.

4. 发明授权

US12036401B2 Seizure detection algorithm adjustment 有权
公开(公告)号：US12036401B2
公开(公告)日：2024-07-16
申请号：US16773719
申请日：2020-01-27
申请人： Medtronic, Inc.
发明人： Jonathon E. Giftakis , Nathan A. Torgerson
IPC分类号： A61N1/05 , A61B5/00 , A61B5/03 , A61N1/36
CPC分类号： A61N1/0534 , A61B5/031 , A61B5/4094 , A61N1/36082
摘要： A medical system implements a seizure detection algorithm to detect a seizure based on a first patient parameter. The medical system monitors a second patient parameter to adjust the seizure detection algorithm. In some examples, the medical system determines whether a seizure for which therapy delivery is desirable occurred based on a second patient parameter. If a target seizure occurred, and the seizure detection algorithm did not detect the target seizure, the medical system adjusts the seizure detection algorithm to detect the target seizure. For example, the medical system may determine a first patient parameter characteristic indicative of the target seizure detected based on the second patient parameter and store the first patient parameter characteristic as part of the seizure detection algorithm. In some examples, the first patient parameter is an electrical brain signal and the second patient parameter is patient activity (e.g., patient motion or posture).

5. 发明公开

US20240172949A1 SYSTEMS AND METHODS FOR MEASURING INTRACRANIAL PRESSURE 审中-公开
公开(公告)号：US20240172949A1
公开(公告)日：2024-05-30
申请号：US18552024
申请日：2022-03-24
申请人： Nelson L. JUMBE , Andreas SCHUH , Michael MORIMOTO , Peter REXELIUS , Steve KRAWCZYK , Andrew URAZAKI
发明人： Nelson L. JUMBE , Andreas SCHUH , Michael MORIMOTO , Peter REXELIUS , Steve KRAWCZYK , Andrew URAZAKI
IPC分类号： A61B5/03 , A61B5/00 , A61B5/053 , A61B7/00
CPC分类号： A61B5/031 , A61B5/053 , A61B5/6803 , A61B7/001 , A61B2562/0204
摘要： There is disclosed a system for monitoring, non-invasively, intracranial pressure of a subject. The system includes a vibroacoustic sensor and an electric potential sensor. The vibroacoustic sensor is configured to detect vibroacoustic signals associated with intracranial pressure of the subject, within a bandwidth ranging from about 0.01 Hz to about 20 kHz. The electric potential sensor is configured to detect electric potential signals reflective of baseline time-based events in the subject for identifying baseline time-based intracranial pressure changes from the detected vibroacoustic signals. The vibroacoustic sensor is housed in a wearable device. The wearable device is configured to be non-invasively coupled to the subject's head.

6. 发明授权

US11992302B2 System and method for non-invasively determining an indication and/or an assessment of intracranial pressure 有权
公开(公告)号：US11992302B2
公开(公告)日：2024-05-28
申请号：US17396015
申请日：2021-08-06
申请人： Vivonics, Inc.
发明人： Michele Pierro
IPC分类号： A61B5/00 , A61B5/03 , A61B5/145
CPC分类号： A61B5/031 , A61B5/0059 , A61B5/14542 , A61B5/6814
摘要： A system for non-invasively determining an indication and/or an assessment of intracranial pressure (ICP) is featured. The system includes at least one intracranial light source adapted to be placed on skin above a cranium of a living subject configured to emit light which penetrates the cranium and targets intracranial space of a living subject. The system includes a least one extracranial light source adapted to be placed on skin above a predetermined area of the living subject configured to emit light which penetrates and targets extracranial space of the living subject. A detector subsystem including at least a first detector is configured to detect reflected light from the intracranial space and the extracranial space and is configured to output intracranial output signals associated with light detected from the intracranial space and/or output extracranial output signals associated with light detected from the extracranial space. A processing subsystem is coupled to the at least one intracranial light source, the at least one extracranial light source, and the detector subsystem. The processing subsystem is configured to determine intracranial oxygen saturation and extracranial oxygen saturation and non-invasively determine an indication and/or an assessment of ICP using a ratio of the intracranial oxygen saturation to the extracranial oxygen saturation.

7. 发明公开

US20240065626A1 DETECTION AND ANALYSIS OF SPATIALLY VARYING FLUID LEVELS USING MAGNETIC SIGNALS 审中-公开
公开(公告)号：US20240065626A1
公开(公告)日：2024-02-29
申请号：US18338496
申请日：2023-06-21
申请人： CEREBROTECH MEDICAL SYSTEMS, INC.
发明人： Richard Warren WYETH , Mitchell Elliott LEVINSON , Bryan Jon WEBER
IPC分类号： A61B5/00 , A61B5/03 , A61B5/05 , A61B5/0522 , A61B5/245 , A61B6/03 , G16H40/67 , G16H50/20
CPC分类号： A61B5/4875 , A61B5/0013 , A61B5/0022 , A61B5/0042 , A61B5/031 , A61B5/05 , A61B5/0522 , A61B5/245 , A61B5/4064 , A61B5/4839 , A61B5/4848 , A61B5/4878 , A61B5/6803 , A61B5/6814 , A61B5/721 , A61B5/7214 , A61B5/7225 , A61B5/7257 , A61B5/7275 , A61B5/7282 , A61B6/032 , G16H40/67 , G16H50/20 , A61B2560/0223 , A61B2562/0223 , A61B2562/166 , A61B2562/182 , A61B2562/222 , A61B2576/026
摘要： A device for detecting spatial differences in fluid level changes in a tissue of a patient may include a support structure for securing the device to a body part of the patient, a processing element operably connected to the support structure, a wireless networking interface operably connected to the support structure and in communication with the processing element and an external computing device via a network, a first transmission module operably connected to the support structure and in communication with the processing element, a second transmission module and a third transmission module operably connected to the support structure and in communication with the processing element. When activated, the first transmission module transmits a first time varying magnetic field through the tissue of the patient. The second and third transmission modules, which are spatially separated from one another, receive first and second versions, respectively, of the first time varying magnetic field.

8. 发明授权

US11883203B2 Skull-mounted drug and pressure sensor 有权
公开(公告)号：US11883203B2
公开(公告)日：2024-01-30
申请号：US16805308
申请日：2020-02-28
申请人： Cognos Therapeutics Inc.
发明人： Yehoshua Shachar , Thomas Chen , Thomas J. Lobl , Jeffrey A. Brydle , Juan R. Gonzalez , Virote Indravudh , Christian Merot , Allan R. Schwartz , Chad Srisathapat
IPC分类号： A61B5/00 , A61B5/1459 , A61B5/03 , A61M5/142 , A61M27/00 , A61M5/14 , A61B5/01 , A61M1/00 , A61B90/00
CPC分类号： A61B5/6868 , A61B5/0031 , A61B5/03 , A61B5/031 , A61B5/1459 , A61B5/4839 , A61M5/142 , A61B5/01 , A61B2090/064 , A61B2562/0233 , A61M1/60 , A61M5/14 , A61M27/006
摘要： A skull-mounted drug and pressure sensor (SOS), a smart pump (ISP) electrically coupled to the SOS and a drug delivery and communications catheter communicating the SOS with the ISP are combined for a first embodiment. A skull-mounted (SOS), a metronomic biofeedback pump (MBP) electrically coupled to the SOS and a drug delivery and communications catheter having a sending and receiving optical fiber communicating the SOS with the MBP are combined for a second embodiment. A third embodiment combines a (SOS), an implantable power and communication unit (PCU) electrically coupled to the SOS, and a drug delivery and communications catheter for communicating the SOS with the PCU and for communicating the exterior source of the drug to the SOS. A fourth embodiment combines a ventricular catheter with a CSF accessible chamber and drug delivery port; and an implantable stand-alone skull-mounted drug and pressure sensor (SPS).

9. 发明授权

US11826283B2 Apparatus for influencing an intraocular pressure 有权
公开(公告)号：US11826283B2
公开(公告)日：2023-11-28
申请号：US16780787
申请日：2020-02-03
申请人： Carl Zeiss Meditec AG
发明人： Bernd Borrmann , Martin Hacker
IPC分类号： A61F9/007 , A61F9/00 , A61B3/16 , A61B17/00 , A61B5/03
CPC分类号： A61F9/00781 , A61F9/0017 , A61B3/16 , A61B5/031 , A61B2017/00022 , A61F2250/0002 , A61F2250/0013 , A61F2250/0068 , A61M2205/332 , A61M2205/3317 , A61M2205/3331 , A61M2205/3344 , A61M2205/3375
摘要： An apparatus for influencing an intraocular pressure (IOP) of an eye with a controllable discharge device which is configured to discharge a liquid from at least one area of the eye. The apparatus includes a first sensor device which captures at least one first value that is characteristic for the IOP of the eye, and a second sensor device, which captures at least one second value that is characteristic for a pressure acting on the eye, and a control device which controls the discharge device at least at times taking account of the first characteristic value and the second characteristic value, wherein the second characteristic value is characteristic for an intracranial pressure and/or cerebrospinal pressure.

10. 发明公开

US20230355118A1 SYSTEM AND METHOD FOR MONITORING PHYSIOLOGICAL PARAMETERS BASED ON CEREBROSPINAL FLUID PRESSURES TAKEN AT TWO OR MORE LOCATIONS 审中-公开
公开(公告)号：US20230355118A1
公开(公告)日：2023-11-09
申请号：US18132174
申请日：2023-04-07
申请人： EnClear Therapies, Inc.
发明人： Rajan Patel , Gregory Martin , Mark Gurguis , Raiden Skodowski
IPC分类号： A61B5/024 , A61B5/00 , A61B5/02 , A61B5/08 , A61B5/03
CPC分类号： A61B5/024 , A61B5/7257 , A61B5/02007 , A61B5/7246 , A61B5/0816 , A61B5/031
摘要： Monitoring cardiopulmonary function of a patient based on cerebrospinal fluid (CSF) pressures involves fluidly communicating a first catheter with a first CSF access site of the patient; fluidly communicating a second catheter with a second CSF access site of the patient; providing, using a first pressure sensor in fluid communication with the first catheter, first pressure readings associated with the first CSF access site; providing, using a second pressure sensor in fluid communication with the second catheter, second pressure readings associated with the second CSF access site; and determining a cardiopulmonary function parameter associated with the patient based on first and second pressure signals derived from the first and second pressure readings. The first CSF access site may be associated with a brain ventricle of the patient and the second CSF access site may be associated with the patient's lumbar.

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