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81. 发明授权

US6086825A Microfabricated structures for facilitating fluid introduction into microfluidic devices 有权
公开(公告)号：US6086825A
公开(公告)日：2000-07-11
申请号：US274811
申请日：1999-03-23
申请人： Steven A. Sundberg , J. Wallace Parce , Calvin Y. H. Chow
发明人： Steven A. Sundberg , J. Wallace Parce , Calvin Y. H. Chow
IPC分类号： B01J19/00 , B01L3/00 , B01L3/02 , G01N27/447 , G01N35/00 , G01N35/10
CPC分类号： G01N27/44791 , B01J19/0093 , B01L3/0244 , B01L3/0262 , B01L3/5025 , B01L3/50255 , B01L3/5027 , B01L3/502715 , B01L3/50273 , G01N27/44743 , B01J2219/00783 , B01J2219/00826 , B01J2219/00831 , B01J2219/00833 , B01J2219/00853 , B01J2219/00891 , B01J2219/00909 , B01L2200/027 , B01L2300/0681 , B01L2300/0816 , B01L2300/0819 , B01L2300/0864 , B01L2400/0406 , B01L2400/0418 , B01L2400/0421 , B01L2400/0487 , B01L2400/0688 , B01L3/502723 , B01L3/502753 , G01N2035/00237 , G01N2035/1037 , Y10T436/25125 , Y10T436/25375 , Y10T436/2575
摘要： Fluid introduction is facilitated through the use of a port which extends entirely through a microfluidic substrate. Capillary forces can be used to retain the fluid within the port, and a series of samples or other fluids may be introduced through a single port by sequentially blowing the fluid out through the substrate and replacing the removed fluid with an alternate fluid, or by displacing the fluid in part with additional fluid. In another aspect, microfluidic substrates have channels which varying in cross-sectional dimension so that capillary action spreads a fluid only within a limited portion of the channel network. In yet another aspect, the introduction ports may include a multiplicity of very small channels leading from the port to a fluid channel, so as to filter out particles or other contaminants which might otherwise block the channel at the junction between the channel and the introduction port.

82. 发明授权

US6080295A Electropipettor and compensation means for electrophoretic bias 失效
公开(公告)号：US6080295A
公开(公告)日：2000-06-27
申请号：US45339
申请日：1998-03-20
申请人： J. Wallace Parce , Michael R. Knapp
发明人： J. Wallace Parce , Michael R. Knapp
IPC分类号： G01N31/20 , B01F13/00 , B01J19/00 , B01L3/00 , B01L3/02 , F04B17/00 , F04B19/00 , G01N27/26 , G01N27/447 , G01N37/00 , H02N11/00
CPC分类号： B01F13/0071 , B01J19/0093 , B01L3/502715 , B01L3/50273 , B01L3/502784 , F04B17/00 , F04B19/006 , G01N27/44704 , G01N27/44743 , G01N27/44791 , H02N11/006 , B01F13/0084 , B01F13/0086 , B01J2219/00891 , B01L2200/027 , B01L2400/0415 , B01L2400/0418 , B01L2400/0421 , B01L3/021 , Y10S366/02 , Y10T436/113332 , Y10T436/2575
摘要： The present invention provides for techniques for transporting materials using electrokinetic forces through the channels of a microfluidic system. The subject materials are transported in regions of high ionic concentration, next to spacer material regions of high ionic concentration, which are separated by spacer material regions of low ionic concentration. Such arrangements allow the materials to remain localized for the transport transit time to avoid mixing of the materials. Using these techniques, an electropipettor which is compatible with the microfluidic system is created so that materials can be easily introduced into the microfluidic system. The present invention also compensates for electrophoretic bias as materials are transported through the channels of the microfluidic system by splitting a channel into portions with positive and negative surface charges and a third electrode between the two portions, or by diffusion of the electrophoresing materials after transport along a channel.

83. 发明授权

US5965001A Variable control of electroosmotic and/or electrophoretic forces within a fluid-containing structure via electrical forces 失效
公开(公告)号：US5965001A
公开(公告)日：1999-10-12
申请号：US888064
申请日：1997-07-03
申请人： Calvin Y. H. Chow , J. Wallace Parce
发明人： Calvin Y. H. Chow , J. Wallace Parce
IPC分类号： G01N27/26 , G01N27/447 , G01N37/00
CPC分类号： G01N27/44791 , G01N27/44713 , G01N27/44752 , G01N27/44773 , Y10S366/02 , Y10T29/49002
摘要： In a microfluidic system using electrokinetic forces, the present invention uses electrical current or electrical parameters, other than voltage, to control the movement of fluids through the channels of the system. Time-multiplexed power supplies also provide further control over fluid movement by varying the voltage on an electrode connected to a fluid reservoir of the microfluidic system, by varying the duty cycle during which the voltage is applied to the electrode, or by a combination of both. A time-multiplexed power supply can also be connected to more than one electrode for a savings in cost.

84. 发明授权

US5699157A Fourier detection of species migrating in a microchannel 失效
标题翻译：傅立叶检测在微通道中迁移的物种
公开(公告)号：US5699157A
公开(公告)日：1997-12-16
申请号：US683080
申请日：1996-07-16
申请人： J. Wallace Parce
发明人： J. Wallace Parce
IPC分类号： G01N27/447 , G01N21/00
CPC分类号： G01N27/44791 , G01N27/44721 , Y10S366/02
摘要： The present invention provides a microfluidic system for fast, accurate and low cost electrophoretic analysis of materials in the fields of chemistry, biochemistry, biotechnology, molecular biology and numerous other fields. Light from periodically spaced regions along a channel in the microfluidic system are received by a photodetector. The intensity of light received by the photodetector is modulated by the movement of species bands through the channel under electrophoretic forces. By Fourier analysis, the velocity of each species band is determined and the identification of the species is made by its electrophoretic mobility in the channel.
摘要翻译：本发明提供了一种用于在化学，生物化学，生物技术，分子生物学等许多领域中快速，准确和低成本电泳分析材料的微流体系统。沿着微流体系统中的通道的周期性间隔的区域的光由光电检测器接收。由光电探测器接收的光的强度通过电泳力通过通道的物种带的移动来调制。通过傅立叶分析，确定每个物种带的速度，并通过其在通道中的电泳迁移率来确定物种的鉴定。

85. 发明授权

US08980644B2 Control of operation conditions within fluidic systems 有权
标题翻译：控制流体系统内的运行条件
公开(公告)号：US08980644B2
公开(公告)日：2015-03-17
申请号：US13453829
申请日：2012-04-23
申请人： J. Wallace Parce , Yung-mae M. Yao , Donald J. Morrissey, Jr.
发明人： J. Wallace Parce , Yung-mae M. Yao , Donald J. Morrissey, Jr.
IPC分类号： G01N1/10 , B01L3/00 , G01N27/447 , G01N35/08 , B01L3/02 , G01N35/00 , G01N35/10
CPC分类号： B01L3/502784 , B01L3/5027 , B01L3/502746 , B01L2200/0673 , B01L2200/0684 , B01L2200/141 , B01L2300/0816 , B01L2300/105 , B01L2300/14 , B01L2400/0415 , B01L2400/0487 , B01L2400/049 , B01L2400/084 , G01N27/44791 , G01N35/08 , G01N2035/00237 , G01N2035/1034 , Y10T137/0324 , Y10T137/0391 , Y10T436/2575
摘要： The invention provides methods of controlling environmental conditions within a fluidic system, where such environmental conditions can affect the operation of the system in its desired function, and fluidic channels, devices, and systems that are used in practicing these methods. Such methods are generally directed to environmental control fluids, the movement of such fluids through these systems, and the interaction of these fluids with other components of the system, e.g., other fluids or solid components of the system.
摘要翻译：本发明提供了控制流体系统内的环境条件的方法，其中这种环境条件可以影响系统在其期望功能中的操作，以及用于实施这些方法的流体通道，装置和系统。这种方法通常涉及环境控制流体，这些流体通过这些系统的运动，以及这些流体与系统的其它部件（例如系统的其它流体或固体组分）的相互作用。

86. 发明授权

US08592037B2 Nanocrystal doped matrixes 有权
标题翻译：纳米晶体掺杂基质
公开(公告)号：US08592037B2
公开(公告)日：2013-11-26
申请号：US13277361
申请日：2011-10-20
申请人： J. Wallace Parce , Paul Bernatis , Robert Dubrow , William P Freeman , Joel Gamoras , Shihai Kan , Andreas Meisel , Baixin Qian , Jeffery A Whiteford , Jonathan Ziebarth
发明人： J. Wallace Parce , Paul Bernatis , Robert Dubrow , William P Freeman , Joel Gamoras , Shihai Kan , Andreas Meisel , Baixin Qian , Jeffery A Whiteford , Jonathan Ziebarth
IPC分类号： B32B9/04
CPC分类号： C09K11/02 , B82Y20/00 , B82Y30/00 , C01B19/007 , C01G9/08 , C01P2002/72 , C01P2002/84 , C01P2004/04 , C01P2004/64 , C01P2004/80 , C01P2004/84 , C09K11/565 , C09K11/70 , C09K11/883 , G02B1/11 , G02B3/0087 , G02B2207/101 , H01L33/502 , Y10S977/783
摘要： Compositions containing a nanostructure, preferably a nanocrystal, are provided. The nanostructures have ligands bound to the surface. Such ligands are preferably siloxane containing ligands having at least one —COON group, although ligands having various ═P═O groups are also contemplated. The nanostructures can be embedded into a polymer such as a silicone polymer.
摘要翻译：提供了包含纳米结构，优选纳米晶体的组合物。纳米结构具有与表面结合的配体。这样的配体优选是具有至少一个-COON基团的含硅氧烷的配位体，尽管也考虑了具有各种= P = O基团的配位体。纳米结构可以嵌入到聚合物如硅氧烷聚合物中。

87. 发明授权

US08558304B2 Methods and devices for forming nanostructure monolayers and devices including such monolayers 有权
标题翻译：用于形成纳米结构单层的方法和装置以及包括这种单层的装置
公开(公告)号：US08558304B2
公开(公告)日：2013-10-15
申请号：US13098082
申请日：2011-04-29
申请人： Jian Chen , Xiangfeng Duan , Chao Liu , Madhuri Nallabolu , J. Wallace Parce , Srikanth Ranganathan
发明人： Jian Chen , Xiangfeng Duan , Chao Liu , Madhuri Nallabolu , J. Wallace Parce , Srikanth Ranganathan
IPC分类号： H01L29/792
CPC分类号： H01L29/66477 , B82Y10/00 , B82Y30/00 , G03F7/0754 , G03F7/165 , G03F7/168 , H01L21/28273 , H01L21/823437 , H01L21/823828 , H01L29/42332 , H01L29/78
摘要： Methods for forming or patterning nanostructure arrays are provided. The methods involve formation of arrays on coatings comprising nanostructure association groups, formation of arrays in spin-on-dielectrics, solvent annealing after nanostructure deposition, patterning using resist, and/or use of devices that facilitate array formation. Related devices for forming nanostructure arrays are also provided, as are devices including nanostructure arrays (e.g., memory devices). Methods for protecting nanostructures from fusion during high temperature processing are also provided.
摘要翻译：提供了形成或构图纳米结构阵列的方法。所述方法包括在包含纳米结构缔合基团，自旋电介质中阵列形成，纳米结构沉积后的溶剂退火，使用抗蚀剂图案化和/或使用促进阵列形成的器件的涂层上形成阵列。还提供了用于形成纳米结构阵列的相关器件，以及包括纳米结构阵列（例如，存储器件）的器件。还提供了在高温处理过程中保护纳米结构不熔化的方法。

88. 发明授权

US08030161B2 Gate electrode for a nonvolatile memory cell 有权
标题翻译：用于非易失性存储单元的栅电极
公开(公告)号：US08030161B2
公开(公告)日：2011-10-04
申请号：US12121591
申请日：2008-05-15
申请人： Xiangfeng Duan , Jian Chen , J. Wallace Parce , Francisco A. Leon
发明人： Xiangfeng Duan , Jian Chen , J. Wallace Parce , Francisco A. Leon
IPC分类号： H01L21/336 , H01L29/788
CPC分类号： H01L29/792 , H01L21/28273 , H01L21/28282 , H01L29/42324 , H01L29/42332 , H01L29/7883 , H01L29/7885
摘要： A nonvolatile memory cell includes a substrate comprising a source, drain, and channel between the source and the drain. A tunnel dielectric layer overlies the channel, and a localized charge storage layer is disposed between the tunnel dielectric layer and a control dielectric layer. A gate electrode has a first surface adjacent to the control dielectric layer, and the first surface includes a midsection and two edge portions. According to one embodiment, the midsection defines a plane, and at least one edge portion extends away from the plane. Preferably, the edge portion extending away from the plane converges toward an opposing second surface of the gate electrode. According to another embodiment, the gate electrode of the nonvolatile memory cell includes a first sublayer and a second sublayer of a different width on the first sublayer.
摘要翻译：非易失性存储单元包括在源极和漏极之间包括源极，漏极和沟道的衬底。隧道介电层覆盖在沟道上，并且局部电荷存储层设置在隧道介电层和控制电介质层之间。栅电极具有与控制电介质层相邻的第一表面，并且第一表面包括中部和两个边缘部分。根据一个实施例，中段限定一个平面，并且至少一个边缘部分远离平面延伸。优选地，远离平面延伸的边缘部分朝向栅电极的相对的第二表面会聚。根据另一实施例，非易失性存储单元的栅极包括第一子层和第一子层上具有不同宽度的第二子层。

89. 发明申请

US20110229795A1 Nanowire-Based Membrane Electrode Assemblies for Fuel Cells 有权
标题翻译：用于燃料电池的基于纳米线的膜电极组件
公开(公告)号：US20110229795A1
公开(公告)日：2011-09-22
申请号：US13149527
申请日：2011-05-31
申请人： Chunming Niu , Calvin Y.H. Chow , Stephen A. Empedocles , J. Wallace Parce
发明人： Chunming Niu , Calvin Y.H. Chow , Stephen A. Empedocles , J. Wallace Parce
IPC分类号： H01M8/10 , B82Y30/00
CPC分类号： H01M4/8605 , B82Y30/00 , H01M4/881 , H01M4/8846 , H01M4/8853 , H01M4/8867 , H01M4/90 , H01M4/9075 , H01M4/921 , H01M4/925 , H01M4/926 , H01M8/023 , H01M8/0232 , H01M8/0234 , H01M8/0236 , H01M8/0241 , H01M8/1004 , H01M8/1007 , H01M8/1011 , H01M8/1086 , Y02E60/523 , Y02P70/56 , Y10S977/762 , Y10S977/948
摘要： The present invention discloses nanowires for use in a fuel cell comprising a metal catalyst deposited on a surface of the nanowires. A membrane electrode assembly for a fuel cell is disclosed which generally comprises a proton exchange membrane, an anode electrode, and a cathode electrode, wherein at least one or more of the anode electrode and cathode electrode comprise an interconnected network of the catalyst supported nanowires. Methods are also disclosed for preparing a membrane electrode assembly and fuel cell based upon an interconnected network of nanowires.
摘要翻译：本发明公开了一种用于燃料电池的纳米线，其包括沉积在纳米线表面上的金属催化剂。公开了一种用于燃料电池的膜电极组件，其通常包括质子交换膜，阳极电极和阴极电极，其中阳极电极和阴极电极中的至少一个或多个包括催化剂负载的纳米线的互连网络。还公开了基于互连的纳米线网络来制备膜电极组件和燃料电池的方法。

90. 发明授权

US07750235B2 Nanostructure and nanocomposite based compositions and photovoltaic devices 失效
标题翻译：纳米结构和纳米复合材料组合物和光伏器件
公开(公告)号：US07750235B2
公开(公告)日：2010-07-06
申请号：US11499599
申请日：2006-08-04
申请人： Erik C. Scher , Mihai Buretea , Calvin Y. H. Chow , Stephen A. Empedocles , Andreas P. Meisel , J. Wallace Parce
发明人： Erik C. Scher , Mihai Buretea , Calvin Y. H. Chow , Stephen A. Empedocles , Andreas P. Meisel , J. Wallace Parce
IPC分类号： H01L31/00 , H01L31/0272 , H01L31/0352 , H01L31/036 , H01L31/04
CPC分类号： H01L31/04 , B82Y10/00 , B82Y20/00 , B82Y30/00 , H01L31/0384 , H01L51/0036 , H01L51/0037 , H01L51/4213 , H01L51/4226 , H01L51/426 , Y02E10/549 , Y02P70/521
摘要： Nanocomposite photovoltaic devices are provided that generally include semiconductor nanocrystals as at least a portion of a photoactive layer. Photovoltaic devices and other layered devices that comprise core-shell nanostructures and/or two populations of nanostructures, where the nanostructures are not necessarily part of a nanocomposite, are also features of the invention. Varied architectures for such devices are also provided including flexible and rigid architectures, planar and non-planar architectures and the like, as are systems incorporating such devices, and methods and systems for fabricating such devices. Compositions comprising two populations of nanostructures of different materials are also a feature of the invention.
摘要翻译：提供纳米复合光伏器件，其通常包括作为光活性层的至少一部分的半导体纳米晶体。包含核 - 壳纳米结构和/或两组纳米结构的光伏器件和其它分层器件，其中纳米结构不一定是纳米复合材料的一部分，也是本发明的特征。还提供了用于这种装置的各种架构，包括柔性和刚性架构，平面和非平面架构等，以及结合这种装置的系统，以及用于制造这种装置的方法和系统。包含两种不同材料的纳米结构群的组合物也是本发明的特征。

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