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41. 发明申请

US20170121271A1 MULTIPHASE REACTOR SYSTEM 有权
公开(公告)号：US20170121271A1
公开(公告)日：2017-05-04
申请号：US15342686
申请日：2016-11-03
申请人： National University of Singapore
发明人： Saif A. Khan , Swee Kun Yap
IPC分类号： C07C209/36 , B01J8/04 , B01J19/24 , B01J8/06
CPC分类号： C07C209/36 , B01J8/0492 , B01J8/065 , B01J19/0046 , B01J19/0093 , B01J19/2425 , B01J2208/06 , B01J2219/00286 , B01J2219/00306 , B01J2219/00353 , B01J2219/00418 , B01J2219/00587 , B01J2219/0072 , B01J2219/00747 , B01J2219/00783 , B01J2219/00792 , B01J2219/00813 , B01J2219/00833 , B01J2219/00835 , B01J2219/0086 , B01J2219/00869 , B01J2219/00871 , B01J2219/00891 , B01J2219/009 , B01J2219/00997 , B01J2219/0254 , B01J2219/0277 , B01J2219/0295 , C07C211/46
摘要： A one-to-many parallelized millireactor system capable of high throughput production in millireactors. Also disclosed is a method for carrying out multi-phase reactions.

42. 发明授权

US09534722B2 Flow passage structure and flow passage structure manufacturing method 有权
标题翻译：流道结构和流道结构制造方法
公开(公告)号：US09534722B2
公开(公告)日：2017-01-03
申请号：US14235311
申请日：2012-08-20
申请人： Koji Noishiki , Tomohiro Suzuki , Yasutake Miwa
发明人： Koji Noishiki , Tomohiro Suzuki , Yasutake Miwa
IPC分类号： B01J19/00 , F16L41/02 , F28D9/00
CPC分类号： F16L41/02 , B01J19/00 , B01J19/0093 , B01J2219/00783 , B01J2219/00786 , B01J2219/00808 , B01J2219/00813 , B01J2219/00822 , B01J2219/00873 , B01J2219/00889 , B01J2219/00891 , B01J2219/0099 , F28D9/00 , F28F2260/02 , Y10T137/0402 , Y10T137/87571 , Y10T137/87652
摘要： A flow passage structure is provided with a fluid flow passage that includes a plurality of straight flow passages, a first return bend that connects the downstream end of the straight flow passage through which a fluid flows from a second end surface toward a first end surface among the plurality of straight flow passages to the upstream end of the straight flow passage which is disposed at the downstream side of the straight flow passage and is adjacent to the straight flow passage, and a second return bend that connects the downstream end of the straight flow passage through which the fluid flows from the first end surface toward the second end surface among the plurality of straight flow passages to the upstream end of the straight flow passage which is disposed at the downstream side of the straight flow passage and is adjacent to the straight flow passage.
摘要翻译：流路结构设置有包括多个直流通道的流体流动通道，第一返回弯曲部，其连接流体从第二端面朝向第一端面流动的直流路的下游端，第一返回弯曲部所述多条直流通道设置在所述直流通道的下游侧并且与所述直流通道相邻的所述直流通道的上游端;以及第二回流弯管，其连接所述直流通道的下游端多个直流通道中的流体从第一端面朝向第二端面流动的直通流路的上游端，该直流通道的上游端设置在直流通道的下游侧并与直线流通道

43. 发明申请

US20160280734A1 AN AUTOMATED, MULTI-POT HIGH-PRESSURE RADIO-SYNTHESIZER FOR PRODUCTION OF PET TRACERS 审中-公开
标题翻译：用于生产PET拖拉机的自动多压高压无线电合成器
公开(公告)号：US20160280734A1
公开(公告)日：2016-09-29
申请号：US14777973
申请日：2014-03-26
申请人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
发明人： Melissa Moore , R. Michael Van Dam , Kevin Quinn , Shane Claggett , Henry Herman , Mark Lazari
IPC分类号： C07H17/02 , B01J14/00
CPC分类号： C07H17/02 , B01J14/00 , B01J19/004 , B01J19/0093 , B01J2219/00799 , B01J2219/00801 , B01J2219/00813 , B01J2219/00815 , B01J2219/00817 , B01J2219/00831 , B01J2219/00873 , B01J2219/00889 , B01J2219/00909 , B01J2219/00918 , B01J2219/0097 , B01J2219/00986
摘要： An automated radiosynthesizer device includes a plurality of reactor assemblies, each reactor assembly being operatively connected to a horizontal actuator for moving the reactor assembly in the horizontal direction and a vertical actuator for moving the reactor assembly in the vertical direction. A plurality of disposable cassettes are disposed above each of the plurality of reactor assemblies, each cassette comprising a lower surface comprising a plurality of sealed and un-sealed gaskets, wherein the un-sealed gaskets are connected to internal fluid paths within the cassette. The device includes a three-axis reagent and gas handling robot disposed above the plurality of cassettes and terminates in a vial gripper and a gas manifold having an inert gas port and a vacuum port. The device includes a control system configured to control the horizontal actuator and vertical actuator of each reactor assembly and the three-axis reagent and gas handling robot.
摘要翻译：一种自动放射合成装置包括多个反应器组件，每个反应器组件可操作地连接到水平致动器，用于在水平方向上移动反应器组件;以及垂直致动器，用于沿垂直方向移动反应堆组件。多个一次性盒被设置在多个反应器组件的每一个上方，每个盒包括下表面，该下表面包括多个密封和未密封的垫圈，其中未密封的垫片连接到盒内的内部流体路径。该装置包括三轴试剂和气体处理机器人，其设置在多个盒的上方并且终止于小瓶夹持器和具有惰性气体端口和真空端口的气体歧管。该装置包括控制系统，其配置成控制每个反应器组件和三轴试剂和气体处理机器人的水平致动器和垂直致动器。

44. 发明申请

US20160001251A1 RUPTURABLE RELIABILITY DEVICES FOR CONTINUOUS FLOW REACTOR ASSEMBLIES 审中-公开
标题翻译：用于连续流动反应器组件的可破坏的可靠性装置
公开(公告)号：US20160001251A1
公开(公告)日：2016-01-07
申请号：US14768639
申请日：2014-02-20
申请人： CORNING INCORPORATED
发明人： Khaled Layouni
IPC分类号： B01J19/00 , G05D7/06 , G05B15/02
CPC分类号： B01J19/0093 , B01J19/0006 , B01J2219/0079 , B01J2219/00813 , B01J2219/00824 , B01J2219/00831 , B01J2219/00867 , B01J2219/00869 , B01J2219/0095 , B01J2219/00988 , G05B15/02 , G05D7/0629
摘要： A flow reactor assembly (10) includes a fluidic module (12,14,16) which include a module body (18) having an internal flow path (20) in communication with an inlet (22) and an outlet (28) and a module burst pressure. A pressure relief valve (36,38,40) relieve pressure within the fluidic module (12,14,16). The pressure relief valves (36,38,40) have a relief pressure value that is less than the module burst pressure. Rupturable reliability devices (50,52,54,56) have a fluid passageway extending therethough through which fluid is received from or directed to the fluidic module (12,14,16). The rupturable reliability device (50,52,54,56) includes a tubular body having a device burst pressure that is greater than the relief valve pressure value (36,38,40) and less than the module burst pressure (12,14,16).
摘要翻译：流动反应器组件（10）包括流体模块（12,14,16），其包括具有与入口（22）和出口（28）连通的内部流动路径（20）的模块主体（18）和模块爆破压力。减压阀（36,38,40）释放流体模块（12,14,16）内的压力。减压阀（36,38,40）具有小于模块爆破压力的溢流压力值。可破坏的可靠性装置（50,52,54,56）具有一个流体通道，从而从流体模块（12,14,16）接收或引导流体。可破坏的可靠性装置（50,52,54,56）包括具有大于溢流阀压力值（36,38,40）且小于模块爆破压力（12,14， 16）。

45. 发明申请

US20150259812A1 SCALABLE CHEMICAL REACTOR AND METHOD OF OPERATION THEREOF 审中-公开
标题翻译：可扩展的化学反应器及其操作方法
公开(公告)号：US20150259812A1
公开(公告)日：2015-09-17
申请号：US14431977
申请日：2013-08-29
申请人： International Business Machines Corporation
发明人： Werner Escher , Patrick Ruch
IPC分类号： C25B15/08 , C25B1/00 , C25B9/18
CPC分类号： C25B15/08 , B01J19/0093 , B01J2219/00783 , B01J2219/00813 , B01J2219/00815 , B01J2219/00822 , B01J2219/00824 , B01J2219/00828 , B01J2219/00833 , B01J2219/00853 , B01J2219/00867 , B01J2219/00869 , B01J2219/00894 , B01J2219/00898 , B01J2219/0093 , B01J2219/00943 , C25B1/003 , C25B9/18 , H01M14/005
摘要： A chemical reactor and method for operation. The reactor enables N pairwise fluid contacts among k chemical fluids, with k≧2 and N≧4 and comprises: a reaction layer extending in a plane subtended by two directions; N chemical cells, each including two circuit portions, designed for enabling circulation of two of the k chemical fluids, respectively, the two circuit portions intersecting each other, thereby enabling one pairwise fluid contact for the two of the k chemical fluids; and a fluid distribution circuit comprising: k sets of inlet orifices sequentially alternating along lines parallel to one of the two directions, for respectively dispensing k chemical fluids to the reaction layer; and k sets of outlet orifices sequentially alternating along lines parallel to the inlet orifices, for respectively collecting k chemical fluids from the reaction layer, and wherein, each circuit portion connects an inlet orifice to an outlet orifice.
摘要翻译：化学反应器及其操作方法。所述反应器使k个化学流体中的N个成对流体接触，其中k≥2和N≥4，并且包括：反应层在沿着两个方向对向的平面中延伸; N个化学电池，每个包括两个电路部分，分别设计用于使k个化学流体中的两个能够循环，两个电路部分彼此相交，从而使两个k个化学流体能够成对流体接触; 以及流体分配电路，包括：k组入口孔，其沿着与所述两个方向中的一个方向平行的线顺序交替，用于分别将k个化学流体分配到所述反应层; 和k组出口孔沿着与入口孔平行的线顺序交替，用于分别从反应层收集k种化学流体，并且其中每个回路部分将入口孔连接到出口孔。

46. 发明申请

US20140366967A1 COMPLEX STRUCTURES IN REFRACTORY BODIES AND METHODS OF FORMING 有权
标题翻译：在炼钢厂的复杂结构和形成方法
公开(公告)号：US20140366967A1
公开(公告)日：2014-12-18
申请号：US14361829
申请日：2012-11-29
申请人： Coming Incorporated
发明人： Paulo Gaspar Jorge Marques
IPC分类号： F16L15/00 , B01J6/00
CPC分类号： F16L15/00 , B01J6/00 , B01J19/0093 , B01J2219/00813 , B01J2219/00824 , B01J2219/00831 , Y10T137/8593
摘要： A method of forming complex structures in a ceramic-, glass- or glass-ceramic-body microfluidic module is disclosed including the steps of providing at green-state refractory- material structure (140) comprising least a portion of a body of a microfluidic module, providing a removeable insert (120) formed of a carbon or of a carbonaceous material having an external surface comprising a negative surface (122) of a desired surface to be formed in the microfluidic module, machining an opening (132) in the green-state structure (140), positioning the insert (120) in the opening (132), firing the green-state structure (140) and the insert (120) together, and after firing is complete, removing the insert (120). The insert (120) is desirably a screw or screw shape, such that interior threads are formed thereby. The insert (120) desirably comprises graphite, and the structure desirably comprises ceramic, desirably silicon carbide.
摘要翻译：公开了一种在陶瓷，玻璃或玻璃 - 陶瓷体微流体模块中形成复杂结构的方法，包括以下步骤：提供在绿色状态的耐火材料结构（140），其包括微流体模块的主体的至少一部分提供由碳或碳质材料形成的可移除插入物（120），所述可移除插入物（120）具有外表面，所述外表面包括要形成在所述微流体模块中的期望表面的负表面（122）状态结构（140），将所述插入件（120）定位在所述开口（132）中，将所述生态结构（140）和所述插入件（120）烧结在一起，并且在点火完成之后，移除所述插入件（120）。插入件（120）理想地是螺钉或螺钉形状，使得内螺纹由此形成。插入件（120）期望地包括石墨，并且该结构理想地包括陶瓷，期望地是碳化硅。

47. 发明申请

US20140264175A1 PROCESS AND APPARATUS FOR CONDUCTING SIMULTANEOUS ENDOTHERMIC AND EXOTHERMIC REACTIONS 有权
标题翻译：用于诱导同时内皮细胞和多发性反应的方法和装置
公开(公告)号：US20140264175A1
公开(公告)日：2014-09-18
申请号：US13802879
申请日：2013-03-14
申请人： VELOCYS, INC.
发明人： Steven T. Perry , Ravi Arora , Martyn Twigg , Bin Yang , Thomas Yuschak , Kai Tod Paul Jarosch , Eric Hans Drescher , Franck Letellier , Anders Gabrielsson
IPC分类号： C01B3/38 , B01J7/00
CPC分类号： C01B3/384 , B01J19/0093 , B01J2219/00783 , B01J2219/00813 , B01J2219/00817 , B01J2219/00822 , B01J2219/00835 , B01J2219/00842 , B01J2219/0086 , B01J2219/00869 , B01J2219/00871 , B01J2219/00873 , B01J2219/00891 , B01J2219/00959 , B01J2219/00961 , B01J2219/00963 , B01J2219/00984 , C01B2203/0233 , C01B2203/0405 , C01B2203/062 , C01B2203/0811 , C01B2203/0822 , C01B2203/0827 , C01B2203/1241 , C01B2203/142 , C01B2203/148 , C01B2203/1604 , Y02P20/128
摘要： This invention relates to a process and an apparatus for conducting simultaneous endothermic and exothermic reactions in a microchannel reactor. A start-up procedure for the microchannel reactor is disclosed.
摘要翻译：本发明涉及在微通道反应器中进行同时吸热和放热反应的方法和装置。公开了一种用于微通道反应器的启动程序。

48. 发明申请

US20140182687A1 HYBRID MICROFLUIDIC ASSEMBLIES 有权
标题翻译：混合微流体装置
公开(公告)号：US20140182687A1
公开(公告)日：2014-07-03
申请号：US14126116
申请日：2012-06-12
申请人： Roland Guidat , Olivier Lobet , Paulo Gasper Jorge Marques , Pierre Woehl
发明人： Roland Guidat , Olivier Lobet , Paulo Gasper Jorge Marques , Pierre Woehl
IPC分类号： B01L3/00
CPC分类号： B01L3/527 , B01J19/0093 , B01J2219/00813 , B01J2219/00824 , B01J2219/00831 , B01J2219/00871 , B01J2219/00873 , B01J2219/00889 , B01L3/5027 , B01L3/502707 , B01L2200/025 , B01L2200/027 , B01L2200/028 , B01L2200/0689 , B01L2300/0867 , B01L2300/0874 , B01L2300/168 , B81B2201/058 , B81C99/0095 , B81C2201/019 , Y10T137/0318 , Y10T137/8359
摘要： Embodiments of hybrid microfluidic assemblies comprise at least one microstructure that is formed of transparent material and is substantially free of non-transparent material and further comprise at least one microstructure that is formed of non-transparent material and is substantially free of transparent material.
摘要翻译：混合微流体组件的实施例包括由透明材料形成并且基本上不含不透明材料的至少一个微结构，并且还包括由不透明材料形成并且基本上不含透明材料的至少一个微观结构。

49. 发明申请

US20140166137A1 FLOW PASSAGE STRUCTURE AND FLOW PASSAGE STRUCTURE MANUFACTURING METHOD 有权
标题翻译：流动通道结构和流动通道结构制造方法
公开(公告)号：US20140166137A1
公开(公告)日：2014-06-19
申请号：US14235311
申请日：2012-08-20
申请人： Koji Noishiki , Tomohiro Suzuki , Yasutake Miwa
发明人： Koji Noishiki , Tomohiro Suzuki , Yasutake Miwa
IPC分类号： F16L41/02
CPC分类号： F16L41/02 , B01J19/00 , B01J19/0093 , B01J2219/00783 , B01J2219/00786 , B01J2219/00808 , B01J2219/00813 , B01J2219/00822 , B01J2219/00873 , B01J2219/00889 , B01J2219/00891 , B01J2219/0099 , F28D9/00 , F28F2260/02 , Y10T137/0402 , Y10T137/87571 , Y10T137/87652
摘要： A flow passage structure is provided with a fluid flow passage that includes a plurality of straight flow passages, a first return bend that connects the downstream end of the straight flow passage through which a fluid flows from a second end surface toward a first end surface among the plurality of straight flow passages to the upstream end of the straight flow passage which is disposed at the downstream side of the straight flow passage and is adjacent to the straight flow passage, and a second return bend that connects the downstream end of the straight flow passage through which the fluid flows from the first end surface toward the second end surface among the plurality of straight flow passages to the upstream end of the straight flow passage which is disposed at the downstream side of the straight flow passage and is adjacent to the straight flow passage.
摘要翻译：流路结构设置有包括多个直流通道的流体流动通道，第一返回弯曲部，其连接流体从第二端面朝向第一端面流动的直流路的下游端，第一返回弯曲部所述多条直流通道设置在所述直流通道的下游侧并且与所述直流通道相邻的所述直流通道的上游端;以及第二回流弯管，其连接所述直流通道的下游端多个直流通道中的流体从第一端面朝向第二端面流动的直通流路的上游端，该直流通道的上游端设置在直流通道的下游侧并与直线流通道

50. 发明申请

US20140072482A1 AUTOMATED SYNTHESIS SYSTEM FOR IODINE-123-IBZM NUCLEAR MEDICINE 审中-公开
标题翻译：自动合成系统，用于碘-123-IBZM核医学
公开(公告)号：US20140072482A1
公开(公告)日：2014-03-13
申请号：US13611710
申请日：2012-09-12
申请人： Chia-Jung Chang , Wei-Kang Chou , An-Shoei Yang , Mei-Hsiu Liao , Lie-Hang Shen
发明人： Chia-Jung Chang , Wei-Kang Chou , An-Shoei Yang , Mei-Hsiu Liao , Lie-Hang Shen
IPC分类号： B01J19/24
CPC分类号： B01J19/004 , B01J19/0093 , B01J2219/00799 , B01J2219/00813 , B01J2219/00817 , B01J2219/00831 , B01J2219/00867 , B01J2219/00889 , B01J2219/00894 , B01J2219/00918 , B01J2219/00927
摘要： An automated synthesis system for iodine-123-IBZM nuclear medicine includes a control/display means, a reactant supply means connecting to the control/display means; an adsorption means connecting to the control/display means and to the reactant supply means, an oxidation means connecting the control/display means, the reactant supply means and the adsorption means, a product collection means connecting to the control/display means, the reactant supply means, the adsorption means and the oxidation means; a waste liquid collection means connecting to the control/display means, the adsorption means and the product collection means, and a gas filtration means connecting the control/display means, the oxidation means and the product collection means. This system can automate the processing steps needed for marking, such as oxidation, reduction, neutralization, adsorption, washing and elution etc, and reduce hand operating time, radiation exposure dose, and mistakes and deviations, while stabilizing the product quality, increasing the product yield, and improving the purity.
摘要翻译：碘-123-IBZM核药物的自动合成系统包括控制/显示装置，连接到控制/显示装置的反应物供应装置; 连接到控制/显示装置和反应物供应装置的吸附装置，连接控制/显示装置，反应物供应装置和吸附装置的氧化装置，连接到控制/显示装置的产品收集装置，反应物供给装置，吸附装置和氧化装置; 连接到控制/显示装置，吸附装置和产品收集装置的废液收集装置，以及连接控制/显示装置，氧化装置和产品收集装置的气体过滤装置。该系统可以自动化氧化，还原，中和，吸附，洗涤和洗脱等标记所需的加工步骤，减少手工操作时间，辐射暴露剂量，错误和偏差，同时稳定产品质量，增加产品产率，提高纯度。

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