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21. 发明申请

US20110110877A1 Hair Cosmetic 有权
标题翻译：头发化妆品
公开(公告)号：US20110110877A1
公开(公告)日：2011-05-12
申请号：US12999767
申请日：2009-06-19
申请人： Tomoko Watanabe , Tomoyuki Kawasoe , Takashi Teshigawara , Reiji Miyahara , Masatoshi Ochiai , Taizo Fujiyama
发明人： Tomoko Watanabe , Tomoyuki Kawasoe , Takashi Teshigawara , Reiji Miyahara , Masatoshi Ochiai , Taizo Fujiyama
IPC分类号： A61K8/49 , A61K8/86 , A61Q5/00 , A61Q5/02
CPC分类号： A61Q5/02 , A61K8/4966 , A61K8/86 , A61Q5/00 , A61Q5/06 , A61Q5/12 , A61Q17/04
摘要： An object of the present invention is to establish means for reliably incorporating a poorly soluble UV-absorbing agent into a hair cosmetic composition, to thereby provide a hair cosmetic composition which has excellent effect of preventing UV-hair damage and which exhibits favorable sensation in use thereof. Specifically, the object can be attained through provision of a hair cosmetic composition including the following ingredients (1) and (2): (1) a polyoxy(lower alkylene) addition compound represented by formula (I): wherein R represents a phytosterol residue or a phytostanol residue; m is a number from 0 to 100; and n is a number from 5 to 100, and (2) a UV-absorbing agent having a triazine group.
摘要翻译：本发明的目的在于建立将难溶性紫外线吸收剂可靠地引入到毛发化妆品中的手段，从而提供具有优异的防止紫外线毛发损伤的效果并且在使用中具有良好感觉的毛发化妆品其中。具体地，可以通过提供包含以下成分（1）和（2）的毛发化妆品组合物来实现：（1）由式（I）表示的聚氧化（低级亚烷基）加成化合物：其中R表示植物甾醇残基或植物甾醇残基; m是从0到100的数字; n为5〜100的数，（2）具有三嗪基的紫外线吸收剂。

22. 发明授权

US06344435B1 Detergent composition 失效
公开(公告)号：US06344435B1
公开(公告)日：2002-02-05
申请号：US09503159
申请日：2000-02-14
申请人： Reiji Miyahara , Koji Abe , Keiichi Uehara , Toshio Fukuda , Takahiro Akutsu
发明人： Reiji Miyahara , Koji Abe , Keiichi Uehara , Toshio Fukuda , Takahiro Akutsu
IPC分类号： C11D165
CPC分类号： C11D9/002 , C07C309/14 , C11D1/04 , C11D1/28
摘要： The present invention is a detergent composition which contains alkali metal N-methyltaurate, alkali metal taurate or alkali metal hypotaurate salt of a specific organic acid or organic alkali N-methyltaurate, organic alkali taurate or organic alkali hypotaurate salt of a specific organic acid. The detergent composition of the present invention is an excellent detergent composition which has better foaming and foam quality, less pH dependence of the foaming, creamy foam, no creaking feeling or stretched feeling and no offensive odor.

23. 发明授权

US5426210A Adduct of cinnamic acid and glycerin, ultraviolet absorbent and external preparation for skin 失效
标题翻译：肉桂酸和甘油的加合物，紫外线吸收剂和皮肤外用剂
公开(公告)号：US5426210A
公开(公告)日：1995-06-20
申请号：US982757
申请日：1993-03-05
申请人： Mikiko Kato , Reiji Miyahara , Keiichi Uehara , Sadaki Takata
发明人： Mikiko Kato , Reiji Miyahara , Keiichi Uehara , Sadaki Takata
IPC分类号： A61K8/37 , A61Q17/04 , C07C59/64 , C07C69/618 , C07C69/734 , C09K3/00 , C07C69/76 , A61K7/44
CPC分类号： A61Q17/04 , A61K8/37 , C07C59/64 , C07C69/734
摘要： An adduct of cinnamic acid and glycerin represented by the following general structural formula (1); ##STR1## (In the general structural formula (1) above, G represents 1 mole of glycerin and e represents average mole number of addition and at least 1. R represents hydrogen or fatty chain. n and k are identified by that (n+k) is 1 to 3, and n and k are 0 to 3 respectively. X represents hydrogen, ion, fatty chain or Gm, and the G represents 1 mole of glycerin, m represents average number of addition and at least 1.), an ultraviolet ray absorbent and an external preparation for skin containing the same.The adduct of cinnamic acid and glycerin according to the present invention have excellent capability to absorb ultraviolet rays as well as high water solubility.
摘要翻译： PCT No.PCT / JP92 / 00587 371日期1993年3月5日 102（e）1993年3月5日PCT PCT。出版物WO92 / 19592 日期：1992年11月12日。由以下通式（1）表示的肉桂酸和甘油的加合物。（1）（在上述通式（1）中，G表示1摩尔甘油，e表示平均加成摩尔数，并且至少为1.R表示氢或脂肪链，n和k由该（n + k）为1〜3，n和k分别为0〜3，X表示氢，离子，脂肪链或Gm，G表示1摩尔甘油，m表示平均加成数，），紫外线吸收剂和含有该紫外线吸收剂的皮肤外用剂。根据本发明的肉桂酸和甘油的加合物具有优异的吸收紫外线的能力以及高的水溶性。

24. 发明申请

US20130331468A1 Production Method Of O/W Emulsion Composition 审中-公开
标题翻译： O / W乳液组合物的生产方法
公开(公告)号：US20130331468A1
公开(公告)日：2013-12-12
申请号：US14001680
申请日：2012-02-22
申请人： Makoto Uyama , Reiji Miyahara , Hidefumi Araki
发明人： Makoto Uyama , Reiji Miyahara , Hidefumi Araki
IPC分类号： A61K8/06
CPC分类号： A61K8/062 , A61K8/042 , A61K8/342 , A61K8/361 , A61K8/37 , A61K8/375 , A61K8/39 , A61K8/442 , A61K8/8111 , A61K8/86 , A61K8/891 , A61K9/107 , A61K47/14 , A61Q19/00
摘要： The present invention provides a production method that can easily produce an O/W emulsion composition without using a special cooling apparatus and be economical. The production method of an O/W emulsion composition comprising the preparation of an emulsified part that is an O/W emulsion by emulsifying, at a temperature of 70° C. or higher, an oil phase comprising (A) a mono-branched fatty acid POE (0-60) glycerin ester, (B) a linear higher alcohol having 16 or more carbon atoms capable to form an α-gel in water with said (A), and (C) an oil component, and a part of an aqueous phase (a first aqueous phase) comprising (D) water; and the cooling of this emulsified part by mixing with stirring the remaining main aqueous phase (a second aqueous phase) at 10 to 35° C., wherein an aqueous solvent in the emulsified part is 15 mass % or less.
摘要翻译：本发明提供一种能够容易地生产O / W乳液组合物而不使用特殊冷却装置并且经济的制备方法。 O / W乳液组合物的制备方法，其包括通过在70℃或更高的温度下乳化含有（A）单支链脂肪酸的油相，制备作为O / W乳液的乳化部分酸性POE（0-60）甘油酯，（B）具有16个或更多碳原子的线性高级醇，其能够与所述（A）在水中形成α-凝胶，和（C）油组分，包含（D）水的水相（第一水相）和通过在10〜35℃下搅拌剩余的主要水相（第二水相）混合，将乳化部分冷却，其中乳化部分中的水性溶剂为15质量％以下。

25. 发明授权

US08580235B2 Hair cosmetic 有权
标题翻译：头发化妆品
公开(公告)号：US08580235B2
公开(公告)日：2013-11-12
申请号：US12999767
申请日：2009-06-19
申请人： Tomoko Watanabe , Tomoyuki Kawasoe , Takashi Teshigawara , Reiji Miyahara , Masatoshi Ochiai , Taizo Fujiyama
发明人： Tomoko Watanabe , Tomoyuki Kawasoe , Takashi Teshigawara , Reiji Miyahara , Masatoshi Ochiai , Taizo Fujiyama
IPC分类号： A61K8/49 , A61K8/86 , A61K31/704 , A61Q5/00 , A61Q5/02
CPC分类号： A61Q5/02 , A61K8/4966 , A61K8/86 , A61Q5/00 , A61Q5/06 , A61Q5/12 , A61Q17/04
摘要： An object of the present invention is to establish means for reliably incorporating a poorly soluble UV-absorbing agent into a hair cosmetic composition, to thereby provide a hair cosmetic composition which has excellent effect of preventing UV-hair damage and which exhibits favorable sensation in use thereof. Specifically, the object can be attained through provision of a hair cosmetic composition including the following ingredients (1) and (2): (1) a polyoxy(lower alkylene) addition compound represented by formula (I): wherein R represents a phytosterol residue or a phytostanol residue; m is a number from 0 to 100; and n is a number from 5 to 100, and (2) a UV-absorbing agent having a triazine group.
摘要翻译：本发明的目的在于建立将难溶性紫外线吸收剂可靠地引入到毛发化妆品中的手段，从而提供具有优异的防止紫外线毛发损伤的效果并且在使用中具有良好感觉的毛发化妆品其中。具体地，可以通过提供包含以下成分（1）和（2）的毛发化妆品组合物来实现：（1）由式（I）表示的聚氧化（低级亚烷基）加成化合物：其中R表示植物甾醇残基或植物甾醇残基; m是从0到100的数字; n为5〜100的数，（2）具有三嗪基的紫外线吸收剂。

26. 发明申请

US20090197948A1 Skin External Preparation 审中-公开
标题翻译：皮肤外用制剂
公开(公告)号：US20090197948A1
公开(公告)日：2009-08-06
申请号：US12301769
申请日：2007-05-22
申请人： Reiji Miyahara , Kouzou Hiwatari , Kei Watanabe , Takashi Oka , Kei-ichi Maruyama , Keiichi Yokozawa
发明人： Reiji Miyahara , Kouzou Hiwatari , Kei Watanabe , Takashi Oka , Kei-ichi Maruyama , Keiichi Yokozawa
IPC分类号： A61K31/375 , C07C43/13 , A61K47/10 , A61K31/05
CPC分类号： A61Q19/00 , A61K8/90 , A61K47/34
摘要： The present invention is to provide a skin external preparation with good moisture retention, a rough skin improving effect, and an improved feeling in use. A skin external preparation comprising a polyoxyalkylene glycol/polyethylene glycol copolymer alkyl ether derivative represented by the below-described general formula (I):(formula I) Y—{O(EO)a/(AO)b—R}k (I) (In the formula, Y is the residue given by removing hydroxyl groups from a polyhydric alcohol having 3 to 6 hydroxyl groups, and k is the number of hydroxyl groups of the polyhydric alcohol. EO is an oxyethylene group; AO is an oxyalkylene group having 3 to 4 carbon atoms, and 1≦a≦70, 1≦b≦70. The percentage of the oxyethylene groups with respect to the sum of the oxyalkylene groups having 3 to 4 carbon atoms and the oxyethylene groups is 20 to 100 mass %. The oxyalkylene group having 3 to 4 carbon atoms and the oxyethylene group are added randomly. Rs are either identical to or different from each other, and they are hydrocarbon groups having 1 to 4 carbon atoms.)
摘要翻译：本发明提供一种具有良好的保湿性，粗糙的皮肤改善效果和改善的使用感的皮肤外用剂。包含由下述通式（I）表示的聚氧化亚烷基二醇/聚乙二醇共聚物烷基醚衍生物的皮肤外用制剂：（式I）<？in-line-formula description =“In-line Formulas”end =“lead “？”Y- {O（EO）a /（AO）bR} k（I）<？in-line-formula description =“In-line Formulas”end =“tail”？>（在公式中，Y是通过从具有3〜6个羟基的多元醇除去羟基而得到的残基，k为多元醇的羟基数，EO为氧化乙烯基，AO为碳原子数3〜4的氧化烯基， 1 <= a <= 70，1 <= b <= 70，氧化乙烯基相对于具有3〜4个碳原子的氧化烯和氧化乙烯基的总和的比例为20〜100质量％，氧化烯随机添加3〜4个碳原子的基团和氧化乙烯基，Rs可以相同也可以不同，它们是具有1〜4个碳原子的烃基 n原子）

27. 发明申请

US20050261370A1 Process for producing of an aminoalkylsulfonic acid and a method of salt exchange for a salt thereof 失效
标题翻译：氨基烷基磺酸的制备方法及其盐的盐交换方法
公开(公告)号：US20050261370A1
公开(公告)日：2005-11-24
申请号：US10526438
申请日：2003-08-27
申请人： Takuhiro Kimura , Tsutomo Tani , Reiji Miyahara
发明人： Takuhiro Kimura , Tsutomo Tani , Reiji Miyahara
IPC分类号： C07C303/22 , C07C303/32 , C07C309/14 , A61K31/205 , C07C39/13
CPC分类号： C07C303/22 , C07C303/32 , C07C309/14
摘要： A process for producing an aminoalkylsulfonic acid of formula [2]: wherein R1 and R2 are each independently hydrogen, alkyl, aryl or aralkyl; and R3 and R4 are each independently hydrogen or alkyl, comprising reacting an aminoalkylsulfonate salt of formula [1]: wherein M is alkali metal, organic ammonium or ammonium ion; and R1 to R4 are as described above, an aqueous solution thereof, or a solution dissolving any one of them in a water-soluble organic solvent, selected from alcohols having 1 to 3 carbon, carboxylic acids having 2 to 12 carbon and dimethylformamide, with an organic acid; and a method of salt exchange for an aminoalkylsulfonate salt of formula [1′]: wherein M′ is alkali metal, organic ammonium or ammonium ion; and R1 and R4 are as described above, comprising reacting the aminoalkylsulfonate salt formula [2] with a hydroxide of formula [6]: M′OH [6]wherein M′ is as described above, in alcohol or water.
摘要翻译：制备式[2]的氨基烷基磺酸的方法：其中R 1和R 2各自独立地为氢，烷基，芳基或芳烷基; R 3和R 4各自独立地为氢或烷基，包括使式[1]的氨基烷基磺酸盐：其中M是碱金属，有机铵或铵离子; 和R 1至R 4如上所述，其水溶液或将它们中的任何一种溶解在水溶性有机溶剂中的溶液，所述溶液选自具有 1至3个碳，具有2至12个碳原子和二甲基甲酰胺的羧酸与有机酸; 和式[1']的氨基烷基磺酸盐的盐交换方法：其中M'是碱金属，有机铵或铵离子; R 1和R 4如上所述，包括使式[2]的氨基烷基磺酸盐与式[6]的氢氧化物反应：<β在线式 description =“In-line Formulas”end =“lead”？> M'OH [6] <？in-line-formula description =“In-line Formulas”end =“tail”？>其中M'如上所述，在酒精或水中。

28. 发明授权

US5977188A Humectant and an endermic liniment 失效
标题翻译：保湿剂和皮肤外用剂
公开(公告)号：US5977188A
公开(公告)日：1999-11-02
申请号：US201150
申请日：1998-11-30
申请人： Tohru Okamoto , Reiji Miyahara
发明人： Tohru Okamoto , Reiji Miyahara
IPC分类号： A61K8/30 , A61K8/00 , A61K8/34 , A61K31/045 , A61Q5/00 , A61Q19/00 , A61Q19/08
CPC分类号： A61Q19/00 , A61K8/345 , A61Q19/08 , A61Q5/00
摘要： A humectant characteristically comprises a diol represented by the following general formula (I):HO--CH.sub.2 --R--CH.sub.2 --OH (I)Wherein R denotes a straight chain or branched chain alkylene group represented by --(C.sub.n H.sub.2n)-- and n denotes an integer 1-3. This a humectant has superior moisture retaining properties and a long lasting skin moisturizing effect, as well as superior usability.
摘要翻译：保湿剂特征在于包含由以下通式（I）表示的二醇：HO-CH 2 -R-CH 2 -OH（I）其中R表示由 - （C n H 2n）表示的直链或支链亚烷基，n表示整数1-3。这种保湿剂具有优异的保湿性能和持久的皮肤保湿效果，以及优异的可用性。

29. 发明授权

US08216597B2 Oil-in-water emulsion composition and method for producing the same 有权
标题翻译：水包油乳液组合物及其制备方法
公开(公告)号：US08216597B2
公开(公告)日：2012-07-10
申请号：US12670895
申请日：2008-07-22
申请人： Takashi Oka , Reiji Miyahara , Takashi Teshigawara
发明人： Takashi Oka , Reiji Miyahara , Takashi Teshigawara
IPC分类号： A61K8/02 , A61K8/00 , A61K9/14 , A61K9/66 , A61Q19/02
CPC分类号： A61K8/0295 , A61K8/062 , A61K8/342 , A61K8/361 , A61K8/375 , A61K8/553 , A61K8/63 , A61K8/86 , A61K9/1075 , A61K47/10 , A61K47/12 , A61K47/14 , A61K2800/21 , A61Q19/00 , B01J13/046
摘要： The present invention provides: an oil-in-water emulsion composition, into which an oil-soluble drug is stably incorporated and which is excellent in feeling during use; and a method for producing the aforementioned composition, which does not require complicated operations. An oil-in-water emulsion composition comprising; (A) a polyoxyethylene phytosterol, (B) a glycerin fatty acid diester, (C) a polyoxyethylene-polyoxypropylene random copolymer dialkyl ether, (D) an oil-soluble drug, (E) oil, and (F) water; wherein a layered gel structure composed of the components (A) and (B) is present in an emulsion particle in the emulsion composition.
摘要翻译：本发明提供一种油包水乳液组合物，其中稳定地掺入油溶性药物，使用时的感觉优异; 以及不需要复杂操作的上述组合物的制造方法。一种水包油乳液组合物，其包含：（A）聚氧乙烯植物甾醇，（B）甘油脂肪酸二酯，（C）聚氧乙烯 - 聚氧丙烯无规共聚物二烷基醚，（D）油溶性药物，（E）油和（F）水; 其中由所述组分（A）和（B）组成的分层凝胶结构物存在于所述乳液组合物中的乳液颗粒中。

30. 发明申请

US20100284949A1 Water-Containing Composition Which Can Be Used As External Composition 审中-公开
标题翻译：含水组合物可作为外部成分使用
公开(公告)号：US20100284949A1
公开(公告)日：2010-11-11
申请号：US12810183
申请日：2008-12-25
申请人： Takashi Teshigawara , Reiji Miyahara , Takashi Oka
发明人： Takashi Teshigawara , Reiji Miyahara , Takashi Oka
IPC分类号： A61K8/33 , A61Q17/04
CPC分类号： A61K8/63 , A61K8/4966 , A61K8/86 , A61K9/0014 , A61K31/575 , A61K47/28 , A61K47/34 , A61Q17/04 , A61Q19/00
摘要： An object of the present invention is to provide means for enhancing ability to solubilize a low water-soluble substance or to disperse the substance in water. The present invention provides a water-containing composition containing water; at least one polyoxyethylene-polyoxypropylene-added phytosterol or phytostanol represented by the following formula (1): [wherein R represents a phytosterol residue or a phytostanol residue; m is a number from 5 to 100; and n is a number from 5 to 100]; and at least one low water-soluble substance which is in a dissolved state.
摘要翻译：本发明的目的是提供增强溶解低水溶性物质或将物质分散在水中的能力的方法。本发明提供含有水的含水组合物，由下式（1）表示的至少一种聚氧乙烯 - 聚氧丙烯添加的植物甾醇或植物甾醇：[其中R表示植物甾醇残基或植物甾醇残基; m是从5到100的数字; n为5〜100的数。和至少一种处于溶解状态的低水溶性物质。

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