专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

21. 发明授权

US5410082A Process for preparing amines 失效
标题翻译：制备胺的方法
公开(公告)号：US5410082A
公开(公告)日：1995-04-25
申请号：US239279
申请日：1994-05-09
申请人： Ralf Pfirmann
发明人： Ralf Pfirmann
IPC分类号： C07B43/04 , C07C209/58 , C07C211/52 , C07C213/00 , C07C215/76 , C07C217/86 , C07C209/50
CPC分类号： C07C209/58
摘要： Process for preparing amines by reacting amides in aqueous-alkaline solutions and/or suspensions with halogens or hypohalites in the presence of alcohols, and converting the reaction products into the amines by hydrolysis, hydrogenation or reductive methods.
摘要翻译：在醇的存在下，通过使酰胺在含水碱性溶液和/或悬浮液中与卤素或次卤酸盐反应制备胺的方法，并通过水解，氢化或还原方法将反应产物转化成胺。

22. 发明授权

US5200556A Process for the preparation of 3,4,6-trifluorophthalic acid and the anhydride thereof 失效
标题翻译：制备3,4,6-三氟乙酸及其无水物的方法
公开(公告)号：US5200556A
公开(公告)日：1993-04-06
申请号：US887182
申请日：1992-05-21
申请人： Theodor Papenfuhs , Ralf Pfirmann
发明人： Theodor Papenfuhs , Ralf Pfirmann
IPC分类号： C07C51/083 , C07C51/377 , C07C51/567 , C07C63/68 , C07D307/89
CPC分类号： C07C51/377 , C07C51/567
摘要： Process for the preparation of 3,4,6-tetrafluorophthalic acid of the formula (1) ##STR1## or the anhydride thereof in good yields and in an advantageous manner, by dehalogenating tetrafluorophthalic anhydride of the formula (2) ##STR2## or tetrafluorophthalic acid in aqueous-alkaline medium using zinc at temperatures of approximately 20.degree. C. to approximately 160.degree. C. and, if appropriate, converting the resulting 3,4,6-trifluorophthalic acid into the anhydride in a known manner by dehydrating it.
摘要翻译：通过使式（2）的四氟邻苯二甲酸脱卤，以良好的产率和有利的方式制备式（1）的3,4,6-四氟邻苯二甲酸（1）或其酸酐的方法

23. 发明授权

US06645904B2 Aminophosphonium compounds 有权
标题翻译：氨基鏻化合物
公开(公告)号：US06645904B2
公开(公告)日：2003-11-11
申请号：US10135252
申请日：2002-04-30
申请人： Berthold Schiemenz , Thomas Wessel , Ralf Pfirmann
发明人： Berthold Schiemenz , Thomas Wessel , Ralf Pfirmann
IPC分类号： C07D26530
CPC分类号： B01J31/0268 , B01J31/0237 , B01J2531/985 , C07B39/00 , C07C45/63 , C07F9/06 , C07F9/572 , C07F9/59 , C07F9/650952 , C07F9/6533 , C07C47/55
摘要： The present invention relates to compounds of the formula in which one, two or three of the radicals R1, R2, R3 and R4 are where m and n are an integer from 1 to 10, R5, R6, R7 and R8 are, independently of one another, identical or different and are a straight-chain or branched alkyl radical having 1 to 10 carbon atoms, and the remaining radical(s) R1 to R4 are or —NR9R10, where R9 and R10 are identical or different and are a straight-chain or branched alkyl radical having 1 to 10 carbon atoms, and X− is an inorganic or organic anion or an equivalent of a multiply charged inorganic or organic anion. The invention further relates to mixtures of substances comprising compounds of the formula (1), to a process for preparing the compounds of the formula (1) and to the use thereof.
摘要翻译：本发明涉及式（1）中的一个，两个或三个基团R 1，R 2，R 3和R 4的化合物，其中m和n是1-10的整数，R R 5，R 7和R 8彼此独立地相同或不同，为具有1-10个碳原子的直链或支链烷基，剩余的基团（ s）R 1至R 4为-NR 9 R 10，其中R 9和R 10相同或不同，为具有1至10个碳原子的直链或支链烷基碳原子，X 1是无机或有机阴离子或等效的多电荷无机或有机阴离子。本发明还涉及包含式（1）化合物的物质的混合物，与制备式（1）化合物的方法及其用途。

24. 发明授权

US06465643B1 Aminophosphonium compounds 有权
标题翻译：氨基鏻化合物
公开(公告)号：US06465643B1
公开(公告)日：2002-10-15
申请号：US09617471
申请日：2000-07-17
申请人： Berthold Schiemenz , Thomas Wessel , Ralf Pfirmann
发明人： Berthold Schiemenz , Thomas Wessel , Ralf Pfirmann
IPC分类号： C07D26530
CPC分类号： B01J31/0268 , B01J31/0237 , B01J2531/985 , C07B39/00 , C07C45/63 , C07F9/06 , C07F9/572 , C07F9/59 , C07F9/650952 , C07F9/6533 , C07C47/55
摘要： The present invention relates to compounds of the formula in which one, two or three of the radicals R1, R2, R3 and R4 are where m and n are an integer from 1 to 10, R5, R6, R7 and R8 are, independently of one another, identical or different and are a straight-chain or branched alkyl radical having 1 to 10 carbon atoms, and the remaining radical(s) R1 to R4 are or —NR9R10, where R9 and R10 are identical or different and are a straight-chain or branched alkyl radical having 1 to 10 carbon atoms, and X− is an inorganic or organic anion or an equivalent of a multiply charged inorganic or organic anion. The invention further relates to mixtures of substances comprising compounds of the formula (1), to a process for preparing the compounds of the formula (1) and to the use thereof.
摘要翻译：本发明涉及式中的一个，两个或三个基团R 1，R 2，R 3和R 4的化合物，其中m和n是1至10的整数，R 5，R 6，R 7和R 8彼此独立地是相同或不同，为具有1至10个碳原子的直链或支链烷基，其余的R 1至R 4基团为-NR 9 R 10，其中R 9和R 10相同或不同，为直链或具有1-10个碳原子的支链烷基，X-是无机或有机阴离子或当量的多电荷无机或有机阴离子。本发明还涉及包含式（1）化合物的物质的混合物，与制备式（1）化合物的方法及其用途。

25. 发明授权

US06348603B1 Process for the preparation of isochroman-3-ones 失效
标题翻译：异苯并二氢吡喃-3-酮的制备方法
公开(公告)号：US06348603B1
公开(公告)日：2002-02-19
申请号：US09668915
申请日：2000-09-25
申请人： Holger Geissler , Ralf Pfirmann
发明人： Holger Geissler , Ralf Pfirmann
IPC分类号： C07D40700
CPC分类号： C07D311/76
摘要： The present invention relates to a process for the preparation of an isochroman-3-one of the formula (I) by reaction of a 1,2-bishalomethylbenzene of the formula (II) in which X is chlorine, bromine or iodine, with carbon monoxide and a compound of the formula (III) R5R6R7C—OH (III) at a CO pressure of 0.1 to 50 MPa and a temperature of 20 to 200° C. in the presence or absence of an ionic halide, in the presence of a palladium catalyst and of a dipolar aprotic solvent, with addition of water or without addition of water, where in the formulae (I) and (II) the radicals R1, R2, R3 and R4 independently of one another are: a hydrogen or fluorine atom; an NC or F3C group; an alkyl, alkoxy or acyloxy radical, in each case having 1 to 18 carbon atoms; or a C6-C18-aryloxy, aryl or heteroaryl radical, where 1 to 3 atoms from the group consisting of O, N and/or S are present as heteroatoms; or in which at least two of the radicals R1, R2, R3 and R4 are linked to one another and form at least one aliphatic or aromatic ring having 5 to 18 carbon atoms, and in formula (III) the radicals R5, R6 and R7 are identical or different and are a C1-C18-alkyl, an HOC(═O)—, H3CC(═O)CH2— or (C6-C18-aryl)-CH2— radical or at least two of the radicals R5, R6 and R7 are linked to one another and form at least one aliphatic or aromatic ring having 5 to 18 carbon atoms.
摘要翻译：本发明涉及一种制备式（I）的异苯并二氢吡喃-3-酮的方法，其中X为氯，溴或碘的式（Ⅱ）的1,2-二沙甲基苯与碳一氧化碳和式（III）化合物在CO 2压力为0.1〜50MPa，温度为20〜200℃的条件下，在钯催化剂存在或不存在下，在钯催化剂和偶极非质子溶剂，加入水或不加入水，其中在式（I）和（II）中，基团R 1，R 2，R 3和R 4彼此独立地为：氢或氟原子; NC或F3C组; 烷基，烷氧基或酰氧基，每种情况具有1至18个碳原子; 或C 6 -C 18芳氧基，芳基或杂芳基，其中以O，N和/或S为基的1至3个原子作为杂原子存在;或其中至少两个基团R 1，R 2，R 3和 R4彼此连接并形成至少一个具有5至18个碳原子的脂族或芳族环，并且在式（III）中，基团R 5，R 6和R 7相同或不同，为C 1 -C 18烷基，HOC （= O） - ，H 3 C（= O）CH 2 - 或（C 6 -C 18 - 芳基）-CH 2 - 基或基团R 5，R 6和R 7中的至少两个彼此连接并形成至少一个脂族或芳族具有5至18个碳原子的环。

26. 发明授权

US5516932A Halogenated cinnamic acids and esters thereof, processes for the preparation thereof and halogenated aryldiazonium salts 失效
标题翻译：卤化肉桂酸及其酯，其制备方法和卤代芳基重氮盐
公开(公告)号：US5516932A
公开(公告)日：1996-05-14
申请号：US178089
申请日：1994-01-06
申请人： Matthias Beller , Hartmut Fischer , Laurent Weisse , Klaus Forstinger , Ralf Pfirmann , Heinz Strutz
发明人： Matthias Beller , Hartmut Fischer , Laurent Weisse , Klaus Forstinger , Ralf Pfirmann , Heinz Strutz
IPC分类号： B01J23/44 , C07B61/00 , C07C57/60 , C07C67/333 , C07C67/343 , C07C69/65 , C07C245/20 , C07C69/76
CPC分类号： C07C245/20 , C07C57/60 , C07C67/343 , C07C69/65
摘要： The present invention relates to compounds of the formula ##STR1## in which R.sup.1 and R.sup.2 are identical or different and are hydrogen or an alkyl radical having 1 to 18 carbon atoms and optionally containing oxygen, nitrogen or halogen, the radicals X, Y and Z are identical and are a fluorine, bromine or iodine atom or if two of the radicals X, Y or Z are identical or all of the radicals X, Y, Z are different from each other, X, Y and Z are a fluorine, chlorine, bromine or iodine atom. The invention further relates to a process for the preparation of the compounds, by reacting an aryldiazonium salt of the formula ##STR2## in which the radicals X, Y and Z are identical and are a fluorine, bromine or iodine atom or, if two of the radicals X, Y and Z are identical or all of the radicals X, Y, Z are different from each other, X, Y and Z are a fluorine, chlorine, bromine or iodine atom and A.sup.(-) is an anion of an acid having a pK.sub.a
摘要翻译：本发明涉及式（I）的化合物，其中R 1和R 2相同或不同并且是氢或具有1至18个碳原子并且任选地含有氧，氮或卤素的烷基，基团X， Y和Z相同并且是氟，溴或碘原子，或者如果基团X，Y或Z中的两个相同或基团X，Y，Z的全部彼此不同，则X，Y和Z是氟，氯，溴或碘原子。本发明还涉及通过使基团X，Y和Z相同且为氟，溴或碘原子的式（II）的芳基重氮盐与式如果基团X，Y和Z中的两个相同或全部基团X，Y，Z彼此不同，X，Y和Z是氟，氯，溴或碘原子，并且A（ - ）是具有pKa <7的酸的阴离子与式（III）的化合物反应，其中R 1和R 2相同或不同，并且是氢或具有1至18个碳原子的烷基，并且任选地含有氧，氮或卤素，在含钯催化剂的存在下，如果合适，加入碱，和式（II）的芳基重氮盐。

27. 发明授权

US5478963A 2,3-difluoro-6-nitrobenzonitrile and 2-chloro-5,6-difluorobenzonitrile-(2,3-difluoro-6-chlorobenzonitrile), process for their preparation and their use for the preparation of 2,3,6-trifluorobenzoic acid 失效
标题翻译： 2,3-二氟-6-硝基苄腈和2-氯-5,6-二氟苄腈 - （2,3-二氟-6-氯苄腈）的制备方法及其用于制备2,3,6-三氟苯甲腈酸
公开(公告)号：US5478963A
公开(公告)日：1995-12-26
申请号：US184039
申请日：1994-01-21
申请人： Ralf Pfirmann , Theodor Papenfuhs
发明人： Ralf Pfirmann , Theodor Papenfuhs
IPC分类号： C07C51/08 , C07C63/70 , C07C253/14 , C07C253/30 , C07C255/50
CPC分类号： C07C255/50
摘要： The present invention describes the novel intermediates 2,3-difluoro-6-nitrobenzonitrile and 2-chloro-5,6-difluorobenzonitrile, a process for their preparation and their advantageous use for the preparation of 2,3,6-trifluorobenzoic acid, which in turn is a valuable intermediate for the preparation of insecticides and antibacterial agents. The intermediates according to the invention are prepared from 2,3,4-trifluoronitrobenzene by fluorine/cyanide exchange and subsequent denitrating chlorination. 2,3,6-Trifluorobenzoic acid can be prepared from the novel intermediates, in a manner known per se in the literature, by simple chlorine/fluorine exchange and subsequent hydrolysis in a process which overall is industrially advantageous and economically favorable.
摘要翻译：本发明描述了新的中间体2,3-二氟-6-硝基苄腈和2-氯-5,6-二氟苯甲腈，其制备方法及其有利于制备2,3,6-三氟苯甲酸，其中这又是制备杀虫剂和抗菌剂的有价值的中间体。根据本发明的中间体通过氟/氰化物交换和随后的脱硝氯化从2,3,4-三氟硝基苯制备。 2,3,6-三氟苯甲酸可以通过简单的氯/氟交换和随后在整体上在工业上有利和经济上有利的方法中的水解，以本文已知的方式从新型中间体制备。

28. 发明授权

US5473095A Process for the preparation of chlorinated 4,5-difluorobenzoic acids, -benzoic acid derivatives and -benzaldehydes 失效
标题翻译：氯代4,5-二氟苯甲酸，苯甲酸衍生物和苯甲醛的制备方法
公开(公告)号：US5473095A
公开(公告)日：1995-12-05
申请号：US187622
申请日：1994-01-27
申请人： Ralf Pfirmann , Theodor Papenfuhs , Georg Weichselbaumer
发明人： Ralf Pfirmann , Theodor Papenfuhs , Georg Weichselbaumer
IPC分类号： C07B61/00 , C07C45/63 , C07C47/55 , C07C51/363 , C07C63/70 , C07C67/307 , C07C69/78 , C07C231/12 , C07C233/65 , C07C253/30 , C07C255/50 , C07C51/60
CPC分类号： C07C51/363 , C07C45/63 , C07C51/567 , C07C67/307
摘要： The present invention relates to a process for the preparation of compounds of the formula ##STR1## in which R.sup.1 is --CN, --COOH, --COOR', R' being an organic radical having 1 to 6 carbon atoms, --CONH.sub.2, --COCl or --CHO and R.sup.2 is H or Cl, which comprises reacting a compound of the formula ##STR2## in which R.sup.1 is as defined above and R.sup.3 is H or Cl, with a chlorinating agent in the presence of a chlorination catalyst at -10.degree. to 200.degree. C.
摘要翻译：本发明涉及制备式（I）化合物的方法，其中R 1是-CN，-COOH，-COOR'，R'是具有1至6个碳原子的有机基团，-CONH 2 ，-COCl或-CHO，并且R 2是H或Cl，其包括使其中R 1如上定义并且R 3是H或Cl的通式为其的化合物（II）与氯化剂在氯化催化剂在-10〜200℃

29. 发明授权

US5274115A N'-substituted N-amino-3,4,5,6-tetrafluorophthalimides 失效
标题翻译： N-取代的N-氨基-3,4,5,6-四氟邻苯二酰亚胺
公开(公告)号：US5274115A
公开(公告)日：1993-12-28
申请号：US872058
申请日：1992-04-23
申请人： Theodor Papenfuhs , Ralf Pfirmann
发明人： Theodor Papenfuhs , Ralf Pfirmann
IPC分类号： C07D209/48 , C07D403/04 , C07D209/34
CPC分类号： C07D209/48
摘要： Compounds of the formula ##STR1## in which X is the radical ##STR2## where R.sub.1 and R.sub.2 are in each case a hydrogen atom, an alkyl-(C.sub.1 -C.sub.10) group, aryl group, alkyl(C.sub.1 -C.sub.6)-CO group or aryl-CO group, where the aryl or aryl-CO group in the case of R.sub.1 and R.sub.2 can be substituted on the aromatic ring by fluorine and/or chlorine atoms and/or alkyl(C.sub.1 -C.sub.4) groups, or R.sub.1 and R.sub.2 together are a phthaloyl radical which can be substituted on the aromatic ring by 4 chlorine atoms or 4 fluorine atoms, or where X is the radical ##STR3## which can be substituted on the aromatic ring by fluorine and/or chlorine atoms and/or alkyl(C.sub.1 -C.sub.4) groups, and processes for their preparation.
摘要翻译：式（1）的化合物，其中X是基团，其中R 1和R 2各自为氢原子，烷基 - （C 1 -C 10）基团，芳基，烷基（C 1 -C 6） -CO基或芳基-CO基，其中在R1和R2的情况下的芳基或芳基-CO基可以在芳环上被氟和/或氯原子和/或烷基（C1-C4）基团取代，或 R1和R2一起是可以在芳环上被4个氯原子或4个氟原子取代的邻苯二甲酰基，或其中X是可以在芳环上被氟和/或氯原子取代的基团， /或烷基（C 1 -C 4）基团，及其制备方法。

30. 发明授权

US5179230A Process for the preparation of 2,3,4,5-tetrafluorobenzoic acid 失效
标题翻译：制备2,3,4,5-四氢叶酸的方法
公开(公告)号：US5179230A
公开(公告)日：1993-01-12
申请号：US872059
申请日：1992-04-23
申请人： Theodor Papenfuhs , Ralf Pfirmann
发明人： Theodor Papenfuhs , Ralf Pfirmann
IPC分类号： C07C51/00 , C07C51/06 , C07C63/70
CPC分类号： C07C51/44 , C07C51/38
摘要： A process for the preparation of 2,3,4,5,-tetrafluorobenzoic acid of the formula (1) ##STR1## by heating N'-substituted N-aminotetrafluorophthalimides of the formula (2) ##STR2## in which X is the radical ##STR3## where R.sub.1, R.sub.2 are a hydrogen atom, an alkyl-(C.sub.1 -C.sub.10)- group, aryl group, alkyl-(C.sub.1 -C.sub.6)-Co- group or aryl-CO- group, it being possible for the aryl or aryl-CO- group in the case of R.sub.1 and R.sub.2 to be substituted on the aromatic ring by fluorine and/or chlorine atoms and/or alkyl-(C.sub.1 -C.sub.4)-groups, or R.sub.1 and R.sub.2 together are a phthaloyl radical which can be substituted on the aromatic ring by 4 chlorine atoms or 4 fluorine atoms, or where X is the radical ##STR4## which can be substituted on the aromatic ring by fluorine and/or chlorine atoms and/or alkyl-(C.sub.1 -C.sub.4)- groups, in an aqueous medium at pH values of approximately -1 to approximately +1 at temperatures of approximately 160 to approximately 220.degree. C.
摘要翻译：通过加热式（2）的N-取代的N-氨基四氟邻苯二甲酰亚胺（2）制备式（1）的2,3,4,5-四氟苯甲酸的方法（1）其中X是基团，其中R 1，R 2是氢原子，烷基 - （C 1 -C 10） - 基，芳基，烷基 - （C 1 -C 6） - 基或芳基-CO-基团， R 1和R 2在芳环上被氟和/或氯原子和/或烷基 - （C 1 -C 4） - 基团取代时，芳基或芳基-CO-基团是有可能的，或者R1和R2 一起是可以在芳环上被4个氯原子或4个氟原子取代的邻苯二甲酰基，或其中X是可以在芳环上被氟和/或氯原子和/或烷基取代的基团 - （C1-C4） - 基团，在约160至约220℃的温度下，pH值约为-1至约+ 1的水性介质中。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式