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21. 发明申请

US20070166478A1 Thermal spray powder and process for producing the same as well as method for spraying the same 审中-公开
标题翻译：热喷粉及其制造方法以及其喷涂方法
公开(公告)号：US20070166478A1
公开(公告)日：2007-07-19
申请号：US11717369
申请日：2007-03-13
申请人： Tsuyoshi Itsukaichi , Satoru Osawa , Isao Aoki
发明人： Tsuyoshi Itsukaichi , Satoru Osawa , Isao Aoki
IPC分类号： B05D1/08
CPC分类号： C23C4/06 , Y10T428/2982
摘要： A thermal spray powder of the present invention includes particles composed of molybdenum disulfide, and a coating layer provided on the surface of each of the particles. The coating layer is composed of a metal that is softened or melted at a temperature lower than the heat decomposition temperature of the molybdenum disulfide. The coating layer is preferably composed of copper. The thermal spray powder suppresses heat decomposition of the molybdenum disulfide contained in the thermal spray powder during thermal spraying.
摘要翻译：本发明的热喷涂粉末包括由二硫化钼组成的颗粒和设置在每个颗粒的表面上的涂层。涂层由在比二硫化钼的分解温度低的温度下软化或熔融的金属构成。涂层优选由铜组成。热喷涂粉末在热喷涂期间抑制热喷涂粉末中所含的二硫化钼的热分解。

22. 发明授权

US07067527B2 Thienopyridine derivatives, their production and use 失效
标题翻译：噻吩并吡啶衍生物，其生产和使用
公开(公告)号：US07067527B2
公开(公告)日：2006-06-27
申请号：US10662165
申请日：2003-09-03
申请人： Tsuneo Yasuma , Atsuo Baba , Haruhiko Makino , Isao Aoki , Toshiaki Nagata
发明人： Tsuneo Yasuma , Atsuo Baba , Haruhiko Makino , Isao Aoki , Toshiaki Nagata
IPC分类号： C07D495/14 , A61K31/38
CPC分类号： C07D495/04 , C07D495/14
摘要： The present invention provides thienopyridine derivatives, which are useful as anti-inflammatory drugs, particularly as remedies for arthritis; processes for producing them, and pharmaceutical compositions containing them. The thienopyridine derivatives are represented by the formula (I): wherein G is a halogen atom, hydroxyl group, an optionally substituted amino group, etc.; alk is an optionally substituted lower alkylene group; X is O, S, —(CH2)q—, etc.; R is an optionally substituted amino group, etc.; ring B is an optionally substituted Y-containing 5- to 8-membered ring whose ring constituent atoms contain no nitrogen atom; Y is O, S, a group of (wherein Ra, Rb and Rc are the same or different and, each is H, a halogen atom, an optionally substituted hydrocarbon group, etc.), etc.; and ring A may be substituted.
摘要翻译：本发明提供可用作抗炎药物的噻吩并吡啶衍生物，特别是作为关节炎的补救剂; 制备它们的方法和含有它们的药物组合物。噻吩并吡啶衍生物由式（I）表示：其中G是卤素原子，羟基，任选取代的氨基等; 烷基是任选取代的低级亚烷基; X是O，S， - （CH 2 CH 2）q - 等; R是任选取代的氨基等; 环B是任选取代的含有Y的5至8元环，其环组成原子不含氮原子; Y是O，S，（其中Ra，Rb和Rc相同或不同，并且各自为H，卤素原子，任选取代的烃基等）等; 并且环A可以被取代。

23. 发明申请

US20050228026A1 Benzimidazole compound crystal 有权
标题翻译：苯并咪唑化合物晶体
公开(公告)号：US20050228026A1
公开(公告)日：2005-10-13
申请号：US11149903
申请日：2005-06-10
申请人： Akira Fujishima , Isao Aoki , Keiji Kamiyama
发明人： Akira Fujishima , Isao Aoki , Keiji Kamiyama
IPC分类号： A61K31/4439 , A61P1/04 , A61P31/04 , C07D401/12 , C07D43/02
CPC分类号： C07D401/12 , A61K31/4439 , C07B2200/13
摘要： A novel crystal of (R)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole or a salt thereof of the present invention is useful for an excellent antiulcer agent.
摘要翻译：（R）-2 - [[3-甲基-4-（2,2,2-三氟乙氧基）-2-吡啶基]甲基]亚磺酰基] -1H-苯并咪唑或其盐的新晶体对于优良的抗溃疡剂是有用的。

24. 发明授权

US06939971B2 Benzimidazole compound crystal 有权
标题翻译：苯并咪唑化合物晶体
公开(公告)号：US06939971B2
公开(公告)日：2005-09-06
申请号：US10655114
申请日：2003-09-04
申请人： Akira Fujishima , Isao Aoki , Keiji Kamiyama
发明人： Akira Fujishima , Isao Aoki , Keiji Kamiyama
IPC分类号： A61K31/4439 , A61P1/04 , A61P31/04 , C07D401/12 , A61K31/44 , C07D401/04
CPC分类号： C07D401/12 , A61K31/4439 , C07B2200/13
摘要： A novel crystal of (R)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole or a salt thereof of the present invention is useful for an excellent antiulcer agent.
摘要翻译：（R）-2 - [[3-甲基-4-（2,2,2-三氟乙氧基）-2-吡啶基]甲基]亚磺酰基] -1H-苯并咪唑或其盐的新结晶为适用于优秀的抗溃疡剂。

25. 发明授权

US5994355A 1, 2, 4-Triazin-3-one derivatives, production and use thereof 失效
标题翻译： 1,2,4-三嗪-3-酮衍生物，的制备和用途
公开(公告)号：US5994355A
公开(公告)日：1999-11-30
申请号：US810499
申请日：1997-02-28
申请人： Hideki Miki , Koichi Iwanaga , Toshimi Matsuno , Isao Aoki
发明人： Hideki Miki , Koichi Iwanaga , Toshimi Matsuno , Isao Aoki
IPC分类号： A01N43/707 , C07C281/10 , C07C281/14 , C07C323/48 , C07D213/61 , C07D253/06 , C07D253/07 , C07D253/075 , C07D271/06 , C07D277/32 , C07D333/28 , C07D401/04 , C07D401/10 , C07D403/12 , C07D409/10 , C07D413/10 , C07D417/10 , A61K31/53
CPC分类号： C07D253/06 , A01N43/707 , C07C281/10 , C07C281/14 , C07C323/48 , C07D213/61 , C07D253/07 , C07D253/075 , C07D271/06 , C07D277/32 , C07D333/28 , C07D401/04 , C07D401/10 , C07D403/12 , C07D409/10 , C07D413/10 , C07D417/10
摘要： The present invention provides a novel triazine derivative of the formula ##STR1## wherein ring A is an optionally substituted aromatic group; X is an oxygen or sulfur atom;R.sup.1 and R.sup.6 are each a hydrogen atom or an optionally substituted hydrocarbon residue or heterocyclic group which may bound through a hetero-atom;R.sup.2 and R.sup.3 are each independently a hydrogen atom, a halogen atom, or a group bound through a carbon, oxygen or sulfur atom, or taken together, represent .dbd.S;R.sup.4 and R.sup.5 are each independently a hydrogen atom, a halogen-atom, or a group bound through a carbon, oxygen, nitrogen or sulfur atom;R.sup.1 and R.sup.2, and R.sup.5 and R.sup.6 may each bind together to form a chemical bond; provided that where ring A is a phenyl group having at least a halogen atom in position -2 or 4 and X is an oxygen atom, R.sup.4 and R.sup.5 do not conjoin to form a chemical bond, or a salt thereof. The invention also encompasses an antiprotozoan composition comprising the novel triazine derivative or a salt thereof.
摘要翻译：本发明提供下式的新型三嗪衍生物，其中环A为任选取代的芳族基团; X是氧或硫原子; R 1和R 6各自是氢原子或可以通过杂原子结合的任选取代的烃残基或杂环基; R2和R3各自独立地为氢原子，卤素原子或通过碳，氧或硫原子结合的基团，或者一起表示= S; R4和R5各自独立地为氢原子，卤素原子或通过碳，氧，氮或硫原子键合的基团; R 1和R 2以及R 5和R 6可以各自结合在一起形成化学键; 其中环A为至少具有-2或4位的卤素原子且X为氧原子的苯基，R4和R5不结合形成化学键或其盐。本发明还包括含有新颖的三嗪衍生物或其盐的抗原生动物组合物。

26. 发明授权

US5364989A 1,1,1-trichloro-2-nitroethane production 失效
标题翻译： 1,1,1-三氯-2-硝基乙烷生产
公开(公告)号：US5364989A
公开(公告)日：1994-11-15
申请号：US908725
申请日：1992-07-06
申请人： Isao Aoki , Takanori Tabuchi , Isao Minamida
发明人： Isao Aoki , Takanori Tabuchi , Isao Minamida
IPC分类号： A01N35/08 , A01N37/52 , A01N43/40 , A01N43/42 , A01N43/78 , C07C205/08 , C07C205/09 , C07C211/27 , C07D213/38 , C07D213/61 , C07D213/64 , C07D213/70 , C07D213/74 , C07D215/12 , C07D239/26 , C07D277/28 , C07D277/32 , C07D277/42 , C07C205/02 , C07C201/06
CPC分类号： C07D213/64 , A01N35/08 , A01N37/52 , A01N43/40 , A01N43/42 , A01N43/78 , C07C201/12 , C07C201/14 , C07C211/27 , C07D213/38 , C07D213/61 , C07D213/70 , C07D213/74 , C07D215/12 , C07D239/26 , C07D277/28 , C07D277/32 , C07D277/42
摘要： Methods for the production of 1,1,1-trihalogeno-2-nitroethanes from 1,1-dihalogenoethylene by using nitric acid or its salt and hydrogen chloride or hydrogen bromide or its salt, and for the production of .alpha.-unsaturated amines from the 1,1,1-trihalogeno-2-nitroethanes which are useful as insecticides.
摘要翻译：通过使用硝酸或其盐和氯化氢或溴化氢或其盐从1,1-二卤代乙烯生产1,1,1-三卤代-2-硝基乙烷的方法，以及用于从可用作杀虫剂的1,1,1-三卤代-2-硝基乙基铵。

27. 发明授权

US08552198B2 Benzimidazole compound crystal 有权
公开(公告)号：US08552198B2
公开(公告)日：2013-10-08
申请号：US13591992
申请日：2012-08-22
申请人： Akira Fujishima , Isao Aoki , Keiji Kamiyama
发明人： Akira Fujishima , Isao Aoki , Keiji Kamiyama
IPC分类号： C07D215/38
CPC分类号： C07D401/12 , A61K31/4439 , C07B2200/13
摘要： A novel crystal of (R)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole or a salt thereof of the present invention is useful for an excellent antiulcer agent.

28. 发明申请

US20120172599A1 SECOND-ORDER NONLINEAR OPTICAL COMPOUND AND NONLINEAR OPTICAL ELEMENT COMPRISING THE SAME 有权
标题翻译：二阶非线性光学化合物和包含其的非线性光学元件
公开(公告)号：US20120172599A1
公开(公告)日：2012-07-05
申请号：US13391948
申请日：2010-08-24
申请人： Akira Otomo , Isao Aoki , Hideki Miki , Hidehisa Tazawa , Shiyoshi Yokoyama
发明人： Akira Otomo , Isao Aoki , Hideki Miki , Hidehisa Tazawa , Shiyoshi Yokoyama
IPC分类号： C07D307/68 , C07D333/22 , C07D471/06 , C07D409/06 , C07F7/18
CPC分类号： G02B1/045 , C07C223/06 , C07D307/30 , C07D307/68 , C07D333/22 , C07D409/06 , C07D409/12 , C07D409/14 , C07D471/06 , C07F7/1804 , C09B23/0066 , C09B23/0075 , C09B69/008 , C09B69/107 , G02B1/046 , G02B6/105 , G02F1/0063 , G02F1/3611 , G02F1/3612 , G02F1/3614 , G02F1/3615
摘要： Problem to Be Solved: to provide a chromophore having a far superior nonlinear optical activity to conventional chromophores and to provide a nonlinear optical element comprising said chromophore.Solution: a chromophore comprising a donor structure D, a π-conjugated bridge structure B, and an acceptor structure A, the donor structure D comprising an aryl group substituted with a substituted oxy group; and a nonlinear optical element comprising said chromophore.
摘要翻译：要解决的问题：提供对常规发色团具有非常优异的非线性光学活性的发色团，并提供包含所述发色团的非线性光学元件。溶液：包含供体结构D，共轭桥结构B和受体结构A的发色团，包含被取代氧基取代的芳基的供体结构D; 和包含所述发色团的非线性光学元件。

29. 发明授权

US07776450B2 Thermal spraying powder comprising chromium carbide and alloy containing cobalt or nickel, thermal spray coating, and hearth roll 有权
标题翻译：包括碳化铬和含有钴或镍的合金的热喷涂粉末，热喷涂和炉底辊
公开(公告)号：US07776450B2
公开(公告)日：2010-08-17
申请号：US12056370
申请日：2008-03-27
申请人： Hiroaki Mizuno , Satoshi Tawada , Isao Aoki , Noriyuki Yasuo , Tatsuo Suidzu , Sho Hashimoto
发明人： Hiroaki Mizuno , Satoshi Tawada , Isao Aoki , Noriyuki Yasuo , Tatsuo Suidzu , Sho Hashimoto
IPC分类号： B32B5/16
CPC分类号： C23C4/06 , B22F1/0096 , B22F3/115 , C22C1/0433 , C22C1/051 , C22C1/1084 , Y10T428/12014 , Y10T428/12181 , Y10T428/12493 , Y10T428/12847 , Y10T428/26 , Y10T428/264 , Y10T428/2982 , Y10T428/31678
摘要： A thermal spraying powder contains 30 to 50% by mass of chromium carbide with the remainder being an alloy containing chromium, aluminum, yttrium, and at least one of cobalt and nickel. The thermal spraying powder has an average particle size of 20 to 60 μm. The thermal spraying powder may contain 20% by mass or less of yttrium oxide in place of a part of the alloy. A thermal spray coating obtained by thermal spraying of the thermal spraying powder, particularly, a thermal spray coating obtained by high-velocity flame spraying of the thermal spraying powder is suitable for the purpose of a hearth roll.
摘要翻译：热喷涂粉末含有30〜50质量％的碳化铬，余量为含有铬，铝，钇，钴和镍中的至少一种的合金。热喷涂粉末的平均粒径为20〜60μm。热喷涂粉末可以含有20质量％以下的氧化钇代替合金的一部分。通过热喷涂粉末，特别是通过热喷涂粉末的高速火焰喷涂获得的热喷涂得到的热喷涂，适用于炉底辊的目的。

30. 发明授权

US07569697B2 Benzimidazole compound crystal 有权
标题翻译：苯并咪唑化合物晶体
公开(公告)号：US07569697B2
公开(公告)日：2009-08-04
申请号：US12006845
申请日：2008-01-07
申请人： Akira Fujishima , Isao Aoki , Keiji Kamiyama
发明人： Akira Fujishima , Isao Aoki , Keiji Kamiyama
IPC分类号： C07D401/04 , A61K31/44
CPC分类号： C07D401/12 , A61K31/4439 , C07B2200/13
摘要： A novel crystal of (R)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl],sulfinyl]-1H-benzimidazole or a salt thereof of the present invention is useful for an excellent antiulcer agent.
摘要翻译：本发明的（R）-2 - [[[3-甲基-4-（2,2,2-三氟乙氧基）-2-吡啶基]甲基]亚磺酰基] -1H-苯并咪唑或其盐的新晶体对于优良的抗溃疡剂是有用的。

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