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1. 发明授权

US09638938B2 Polarizing lens and method of manufacturing the same 有权
公开(公告)号：US09638938B2
公开(公告)日：2017-05-02
申请号：US14355944
申请日：2013-08-02
申请人： Daisuke Ogaya , Toshihiko Shimizu , Kenichi Tonouchi , Akinori Yamamoto , Masaki Ihara
发明人： Daisuke Ogaya , Toshihiko Shimizu , Kenichi Tonouchi , Akinori Yamamoto , Masaki Ihara
IPC分类号： G02C3/00 , G02C7/12 , B29C39/10 , B29D11/00 , G02B5/30
CPC分类号： G02C7/12 , B29C39/10 , B29D11/00413 , B29D11/00528 , B29D11/00644 , B29D11/0073 , B29K2715/006 , G02B5/3033
摘要： The invention relates to a method of manufacturing a polarizing lens, including conducting curved surface processing to change a shape of a polarizing film into a shape of a curved surface, conducting heat treatment by heating polarizing film that has been processed into a curved surface to a heating temperature of equal to or higher than 105° C. but less than 150° C., assembling an upper mold, a lower mold, and a seal member to provide a casting mold having a cavity within which the polarizing film following heating treatment is positioned, upper and lower molds being positioned opposite each other to sandwich the polarizing film at a space therebetween, and seal member sealing space between the upper and lower molds, casting a curable composition into the cavity, curing curable composition to provide a polarizing lens within which a polarizing film is positioned, and separating polarizing lens thus provided from casting mold.

2. 发明申请

US20140293217A1 POLARIZING LENS AND METHOD OF MANUFACTURING THE SAME 有权
标题翻译：偏振透镜及其制造方法
公开(公告)号：US20140293217A1
公开(公告)日：2014-10-02
申请号：US14355944
申请日：2013-08-02
申请人： Daisuke Ogaya , Toshihiko Shimizu , Kenichi Tonouchi , Akinori Yamamoto , Masaki Ihara
发明人： Daisuke Ogaya , Toshihiko Shimizu , Kenichi Tonouchi , Akinori Yamamoto , Masaki Ihara
IPC分类号： G02C7/12
CPC分类号： G02C7/12 , B29C39/10 , B29D11/00413 , B29D11/00528 , B29D11/00644 , B29D11/0073 , B29K2715/006 , G02B5/3033
摘要： The invention relates to a method of manufacturing a polarizing lens, including conducting curved surface processing to change a shape of a polarizing film into a shape of a curved surface, conducting heat treatment by heating polarizing film that has been processed into a curved surface to a heating temperature of equal to or higher than 105° C. but less than 150° C., assembling an upper mold, a lower mold, and a seal member to provide a casting mold having a cavity within which the polarizing film following heating treatment is positioned, upper and lower molds being positioned opposite each other to sandwich the polarizing film at a space therebetween, and seal member sealing space between the upper and lower molds, casting a curable composition into the cavity, curing curable composition to provide a polarizing lens within which a polarizing film is positioned, and separating polarizing lens thus provided from casting mold.
摘要翻译：本发明涉及一种制造偏振透镜的方法，包括进行弯曲表面处理以将偏振膜的形状改变为曲面形状，通过将加工成弯曲表面的偏振膜加热至加热温度等于或高于105℃但小于150℃，组装上模具，下模具和密封构件，以提供具有空腔的铸模，其中加热处理后的偏振膜为定位的上模具和下模具彼此相对地定位以将偏振膜夹在它们之间的空间处，以及上模和下模之间的密封构件密封空间，将可固化组合物浇注到空腔中，固化可固化组合物以在其内提供偏振透镜偏光膜被定位，并且从铸模中分离出偏振透镜。

3. 发明申请

US20090155453A1 Manufacturing Method and Apparatus of Optical Goods 失效
标题翻译：光学制品的制造方法和装置
公开(公告)号：US20090155453A1
公开(公告)日：2009-06-18
申请号：US12336906
申请日：2008-12-17
申请人： Masaki Ihara , Toru Saito , Akinori Yamamoto
发明人： Masaki Ihara , Toru Saito , Akinori Yamamoto
IPC分类号： B05D5/06 , B05C11/00
CPC分类号： B29D11/00951 , B29C39/006 , B29C39/44 , B29K2105/0094 , B29L2011/0016 , Y10T137/2506
摘要： A manufacturing method of optical goods, including: injecting a material composition stored in a tank into a cavity provided inside a mold; and polymerizing and curing the injected material composition, in which a viscosity of the material composition stored in the tank is measured.
摘要翻译：一种光学制品的制造方法，包括：将储存在罐中的材料组合物注入设置在模具内的空腔中; 并且对其中测量储存在罐中的材料组合物的粘度的注入材料组合物进行聚合和固化。

4. 发明申请

US20090156781A1 Manufacturing Method and Apparatus of Optical Material 失效
标题翻译：光学材料的制造方法和装置
公开(公告)号：US20090156781A1
公开(公告)日：2009-06-18
申请号：US12336934
申请日：2008-12-17
申请人： Masaki Ihara , Toru Saito , Akinori Yamamoto
发明人： Masaki Ihara , Toru Saito , Akinori Yamamoto
IPC分类号： C08G75/04 , G01N11/00
CPC分类号： G02B1/04 , B29C39/006 , B29D11/00442 , B29L2011/0016 , C08G75/08 , C08K3/06 , C08K3/30 , C08L81/02 , C08L2666/54
摘要： A manufacturing method of an optical material, the method including: blending an inorganic compound (a) containing at least one of a sulfur atom and a selenium atom and a compound (b) represented by a following formula (1) in a tank, the compound (a) and the compound (b) being blended at a ratio of 1 mass % or more and 50 mass % or less of the compound (a) and 50 mass % or more and 99 mass % or less of the compound (b) relative to a total mass of a mixture of the compound (a) and the compound (b); mixing a compound (c) containing at least one thiol (SH) group; preliminarily polymerizing the compounds; cooling the compounds; and deaerating the compounds, in which a viscosity of the composition stored in the tank is controlled during at least one of the preliminarily polymerizing, the cooling and the deaerating. (m represents an integer of 0 to 4, and n represents an integer of 0 to 2)
摘要翻译：光学材料的制造方法，其特征在于，将含有硫原子和硒原子中的至少一种的无机化合物（a）和下述式（1）所示的化合物（b））混合在槽中，化合物（a）和化合物（b）以化合物（a）的1质量％以上且50质量％以下的比例和50质量％以上且99质量％以下的化合物（b ）相对于化合物（a）和化合物（b）的混合物的总质量; 混合含有至少一个硫醇（SH）基团的化合物（c）预先使化合物聚合; 冷却化合物; 并且在至少一个预聚合，冷却和脱气的过程中控制储存在罐中的组合物的粘度的化合物脱气。（m表示0〜4的整数，n表示0〜2的整数）

5. 发明授权

US08394300B2 Manufacturing method of optical goods 失效
标题翻译：光学制品的制造方法
公开(公告)号：US08394300B2
公开(公告)日：2013-03-12
申请号：US12336906
申请日：2008-12-17
申请人： Masaki Ihara , Toru Saito , Akinori Yamamoto
发明人： Masaki Ihara , Toru Saito , Akinori Yamamoto
IPC分类号： B29D11/00 , B29C45/00 , G05D24/00 , G05D11/12
CPC分类号： B29D11/00951 , B29C39/006 , B29C39/44 , B29K2105/0094 , B29L2011/0016 , Y10T137/2506
摘要： A manufacturing method of optical goods, including: injecting a material composition stored in a tank into a cavity provided inside a mold; and polymerizing and curing the injected material composition, in which a viscosity of the material composition stored in the tank is measured.
摘要翻译：一种光学制品的制造方法，包括：将储存在罐中的材料组合物注入设置在模具内的空腔中; 并且对其中测量储存在罐中的材料组合物的粘度的注入材料组合物进行聚合和固化。

6. 发明授权

US08013084B2 Manufacturing method and apparatus of optical material 失效
标题翻译：光学材料的制造方法和装置
公开(公告)号：US08013084B2
公开(公告)日：2011-09-06
申请号：US12336934
申请日：2008-12-17
申请人： Masaki Ihara , Toru Saito , Akinori Yamamoto
发明人： Masaki Ihara , Toru Saito , Akinori Yamamoto
IPC分类号： C08G75/04 , C08G75/08 , C08L81/02
CPC分类号： G02B1/04 , B29C39/006 , B29D11/00442 , B29L2011/0016 , C08G75/08 , C08K3/06 , C08K3/30 , C08L81/02 , C08L2666/54
摘要： A manufacturing method of an optical material, the method including: blending an inorganic compound (a) containing at least one of a sulfur atom and a selenium atom and a compound (b) represented by a following formula (1) in a tank, the compound (a) and the compound (b) being blended at a ratio of 1 mass % or more and 50 mass % or less of the compound (a) and 50 mass % or more and 99 mass % or less of the compound (b) relative to a total mass of a mixture of the compound (a) and the compound (b); mixing a compound (c) containing at least one thiol (SH) group; preliminarily polymerizing the compounds; cooling the compounds; and deaerating the compounds, in which a viscosity of the composition stored in the tank is controlled during at least one of the preliminarily polymerizing, the cooling and the deaerating (m represents an integer of 0 to 4, and n represents an integer of 0 to 2).
摘要翻译：光学材料的制造方法，其特征在于，将含有硫原子和硒原子中的至少一种的无机化合物（a）和下述式（1）所示的化合物（b））混合在槽中，化合物（a）和化合物（b）以化合物（a）的1质量％以上且50质量％以下的比例和50质量％以上且99质量％以下的化合物（b ）相对于化合物（a）和化合物（b）的混合物的总质量; 混合含有至少一个硫醇（SH）基团的化合物（c）预先使化合物聚合; 冷却化合物; 在预聚合，冷却和脱气中的至少一种（m表示0〜4的整数，n表示0〜0的整数）中控制储存在罐中的组合物的粘度的化合物脱气 2）。

7. 发明申请

US20120270338A1 FLUOROIMMUNOASSAY METHOD 审中-公开
标题翻译：荧光分光法
公开(公告)号：US20120270338A1
公开(公告)日：2012-10-25
申请号：US13510105
申请日：2010-11-19
申请人： Hiroshi Ueda , Ryoji Abe , Masaki Ihara , Hiroaki Takagi
发明人： Hiroshi Ueda , Ryoji Abe , Masaki Ihara , Hiroaki Takagi
IPC分类号： G01N21/76 , C07K17/02
CPC分类号： G01N33/582 , A61K49/0058 , C07K16/18 , C07K16/44 , C07K2317/56 , C07K2317/622 , C07K2317/92 , G01N21/6428 , G01N33/6857 , G01N2021/6439
摘要： An object is to provide an immunoassay method requiring neither a solid-phase immobilization step nor a washing step, enabling quick and simple quantitative measurement of a target substance in a liquid phase and capable of visualizing an antigen. Such an object is attained by measuring the concentration of a target antigen present in a test substance by sequentially performing a step (a) of bringing an antibody light-chain variable region polypeptide and an antibody heavy-chain variable region polypeptide labeled with a fluorescent dye into contact with an antigen in a test substance in a liquid phase; or bringing an antibody heavy-chain variable region polypeptide and an antibody light-chain variable region polypeptide labeled with a fluorescent dye into contact with an antigen in a test substance in a liquid phase; a step (b) of measuring the fluorescence intensity of the fluorescent dye; and a step (c) of computationally obtaining the level of the antigen contained in the test substance with reference to a positive correlation between the concentration of the antigen in a liquid phase and the fluorescence intensity of the fluorescent dye.
摘要翻译：本发明的目的是提供一种不需要固相固定步骤和洗涤步骤的免疫测定方法，能够快速和简单地定量测定液相中的目标物质并能够使抗原呈现。通过依次进行使荧光染料标记的抗体轻链可变区多肽和抗体重链可变区多肽的步骤（a），测定待测物质中存在的靶抗原的浓度，与液相中测试物质中的抗原接触; 或使用荧光染料标记的抗体重链可变区多肽和抗体轻链可变区多肽与液相中的测试物质中的抗原接触; 测量荧光染料的荧光强度的步骤（b）; 和（c）参考在液相中的抗原浓度与荧光染料的荧光强度之间的正相关性来计算获得测试物质中含有的抗原水平的步骤（c）。

8. 发明授权

US06638942B1 Spiro-indolines as Y5 receptor antagonists 失效
标题翻译：螺吲哚啉作为Y5受体拮抗剂
公开(公告)号：US06638942B1
公开(公告)日：2003-10-28
申请号：US10228250
申请日：2002-08-26
申请人： Ying-Duo Gao , Douglas J. MacNeil , Lihu Yang , Nancy R. Morin , Takehiro Fukami , Akio Kanatani , Takahiro Fukuroda , Yasuyuki Ishii , Masaki Ihara
发明人： Ying-Duo Gao , Douglas J. MacNeil , Lihu Yang , Nancy R. Morin , Takehiro Fukami , Akio Kanatani , Takahiro Fukuroda , Yasuyuki Ishii , Masaki Ihara
IPC分类号： C07D47110
CPC分类号： C07D221/20 , C07D471/10
摘要： Compounds of general structural formula I are selective NPY Y5 receptor antagonists, useful in the treatment of obesity and the complications associated therewith.
摘要翻译：通用结构式的化合物Iare选择性NPY Y5受体拮抗剂，可用于治疗肥胖及其相关并发症。

9. 发明授权

US5114918A Endothelin antagonistic cyclic pentapeptides 失效
标题翻译：内皮素拮抗剂环糊精
公开(公告)号：US5114918A
公开(公告)日：1992-05-19
申请号：US630505
申请日：1990-12-20
申请人： Kiyofumi Ishikawa , Takehiro Fukami , Takashi Hayama , Kenji Niiyama , Toshio Nagase , Toshiaki Mase , Kagari Fujita , Masaru Nishikibe , Masaki Ihara , Mitsuo Yano
发明人： Kiyofumi Ishikawa , Takehiro Fukami , Takashi Hayama , Kenji Niiyama , Toshio Nagase , Toshiaki Mase , Kagari Fujita , Masaru Nishikibe , Masaki Ihara , Mitsuo Yano
IPC分类号： A61K38/00 , C07K7/64 , C07K14/575
CPC分类号： C07K14/57536 , A61K38/00 , Y10S514/826 , Y10S514/921 , Y10S514/922 , Y10S514/929 , Y10S530/80 , Y10S930/27
摘要： Cyclic pentapeptides of the formula:cyclo (-X.sup.1 -X.sup.2 -X.sup.3 -X.sup.4 -X.sup.5 -) (I)wherein X.sup.n (n=1-5) represents amino acid residues. These compounds are useful as hypotensive drugs.

10. 发明申请

US20110237462A1 IMMOBILIZATION SUBSTRATE AND METHOD FOR PRODUCING THE SAME 审中-公开
标题翻译：固定基材及其制造方法
公开(公告)号：US20110237462A1
公开(公告)日：2011-09-29
申请号：US13132834
申请日：2009-12-04
申请人： Koichi Minami , Hirohiko Tsuzuki , Hiroshi Ueda , Masaki Ihara
发明人： Koichi Minami , Hirohiko Tsuzuki , Hiroshi Ueda , Masaki Ihara
IPC分类号： C40B40/10 , C40B50/14
CPC分类号： G01N33/54353
摘要： An antibody-fragment-immobilizing substrate includes a substrate and at least one set of antibody fragments, wherein antibody fragments of each set include at least two types of separate antibody fragments, the at least two types of separate antibody fragments include at least one type of labeled antibody fragment having a labeled site labeled with a luminescent substance and at least one type of acceptor antibody fragment having an acceptor site for accepting emission from the labeled antibody fragment, and the at least one type of labeled antibody fragment and the at least one type of acceptor antibody fragment are capable of cooperatively recognizing one type of antigen in combination and are independently immobilized on the substrate in a positional relationship that allows each of the antibody fragments in one set to bind to the same antigen.
摘要翻译：抗体片段固定的底物包括底物和至少一组抗体片段，其中每组的抗体片段包括至少两种类型的分离的抗体片段，所述至少两种类型的分离的抗体片段包括至少一种类型的具有用发光物质标记的标记位点的标记抗体片段和至少一种具有用于接受来自标记抗体片段的发射的受体位点的受体抗体片段，以及至少一种类型的标记抗体片段和至少一种类型的受体抗体片段能够组合地协同识别一种类型的抗原，并以允许一组中的每个抗体片段结合相同抗原的位置关系独立地固定在底物上。

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