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    • 4. 发明公开
    • 오르토-니트로벤질 에스테르 화합물 및 이를 포함하는 포지티브형 감광성 수지 조성물
    • 邻氨基苯甲酸酯化合物和包含其的阳性类型的感光性树脂组合物
    • KR1020110069467A
    • 2011-06-23
    • KR1020090126211
    • 2009-12-17
    • 제일모직주식회사
    • 정민국유용식조현용이정우정지영이종화정두영전환승
    • C07C205/42C08G73/22C08K5/32G03F7/004
    • C07C205/42C08G73/22C08K5/32G03F7/004G03F7/0045G03F7/039G03F7/0392
    • PURPOSE: A positive type photosensitive resin composition including an ortho-nitrobenzyl ester compound is provided to ensure excellent sensitivity, resolution, pattern formation capablity and residue removal proeprty. CONSTITUTION: An ortho-nitrobenzyl ester compound includes a compound represented by chemical formula 1, a compound represented by chemical formula 2, or combination thereof. In chemical formulas 1 and 2, R1, R2, R5 and R6 are the same and different and represent substituted or unsubstituted aliphatic organic group or substituted or unsubstituted alicyclic organic group; R3 and R7 are the same and different and represent a single bond, or substituted or unsubstituted divalent organic group; R4, R8 and R9 are the same and different and represent substituted or unsubstituted aliphatic organic group or substituted or unsubstituted alicyclic organic group; n1 is an integer of 1-5; n2 is an integer of 0-3; n3 is an integer of 0-4; and n2+n3 is an integer of 1 or greater.
    • 目的:提供包含邻硝基苄基酯化合物的正型感光性树脂组合物,以确保优异的灵敏度,分辨率,图案形成能力和残留物去除率。 构成:邻硝基苄基酯化合物包括由化学式1表示的化合物,由化学式2表示的化合物或其组合。 在化学式1和2中,R 1,R 2,R 5和R 6相同且不同,表示取代或未取代的脂族有机基团或取代或未取代的脂环族有机基团; R3和R7相同且不同,表示单键或取代或未取代的二价有机基团; R4,R8和R9相同且不同,表示取代或未取代的脂族有机基团或取代或未取代的脂环族有机基团; n1为1-5的整数; n2是0-3的整数; n3是0-4的整数; n2 + n3为1以上的整数。
    • 9. 发明授权
    • PROCESS FOR PREPARING CHIRAL INTERMEDIATES USEFUL IN SYNTHESIS OF ATORVASTATIN
    • 制备合成ATORVASTATIN的手术中间体的方法
    • KR100763770B1
    • 2007-10-08
    • KR20060048194
    • 2006-05-29
    • CHO DONG OCK
    • CHO DONG OCKKIM YEONG SOOKHA HYUNG HO
    • C07C205/42C07C205/14
    • A method for preparing t-butyl (R)-7-nitro-5-hydroxy-3-oxo-heptanoates is provided to produce chiral intermediates useful in a synthesis of atorvastatin in an economical and efficient manner. A method for preparing t-butyl (R)-7-nitro-5-hydroxy-3-oxo-heptanoates comprises the steps of: (i) subjecting (S)-3-hydroxy-butylactone represented by the formula 2 to a decyclization reaction in the presence of an iodine catalyst, acetic acid, ethanol, and hydrogen bromide, followed by reacting the resultant with nitromethane(CH3NO2) to prepare ethyl (R)-5-nitro-3-hydroxypentanoates represented by the formula 3; and (ii) subjecting the ethyl (R)-5-nitro-3-hydroxypentanoates represented by the formula 3 and t-butyl bromoacetate(BrCH2COOt-Bu) to a Grignard reaction using zinc or magnesium to prepare t-butyl (R)-7-nitro-5-hydroxy-3-oxo-heptanoates represented by the following formula 1.
    • 提供了制备(R)-7-硝基-5-羟基-3-氧代庚酸叔丁酯的方法,以便以经济和有效的方式制备可用于合成阿托伐他汀的手性中间体。 制备(R)-7-硝基-5-羟基-3-氧代 - 庚酸叔丁酯的方法包括以下步骤:(i)使由式2表示的(S)-3-羟基丁基内酯进行二环化 在碘催化剂,乙酸,乙醇和溴化氢的存在下进行反应,然后使所得物与硝基甲烷(CH 3 NO 2)反应,制备由式3表示的(R)-5-硝基-3-羟基戊酸乙酯; 和(ii)使用锌或镁处理由式3表示的(R)-5-硝基-3-羟基戊酸乙酯和溴乙酸叔丁酯(BrCH 2 COOt-Bu)进行格氏反应,制备(R) - 由下式1表示的7-硝基-5-羟基-3-氧代 - 庚酸酯。