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    • 1. 发明公开
    • 표면증강라만산란 기질용 은 나노 구조체의 제조방법 및 이에 따른 은 나노 구조체
    • 表面增强拉曼散射基板和银纳米结构的银纳米结构的制备方法
    • KR1020140027786A
    • 2014-03-07
    • KR1020120093815
    • 2012-08-27
    • 강원대학교산학협력단
    • 권찬호엄소영류세림김홍래
    • C01G5/00B01J19/18B82B1/00B82B3/00
    • C22C5/06B22F9/24B22F2301/255B22F2304/054B82Y40/00C22B11/04Y10S977/895Y10S977/954Y10T428/12014
    • The present invention relates to a method for manufacturing silver nanostructures for a surface enhanced raman scattering substrate, and silver nanostructures thereby. The method for manufacturing silver nanostructures for a surface enhanced raman scattering substrate specifies concentrations, mixing speed, one-time added amount, adding speed, and a total added amount etc. of silver nitrate and a reducing agent, which can not be inferred from the existing manufacturing methods. Thereby, the silver nanostructures manufactured have a uniform average size and provide a hot spot, which is an electromagnetic field having a remarkably strong shape of particles, such that the silver nanostructures can not only be manufactured to have reproducibility in a multimer shape, wherein SERS signals are enhanced, but also to be effective in mass-production of the silver nanostructures for a surface enhanced raman scattering substrate. [Reference numerals] (AA) Relative activity; (BB) Adding speed, 쨉L/s; (CC) Examples 2-1 to 2-10; (DD) Examples 1-1 to 1-10
    • 本发明涉及一种用于制造表面增强拉曼散射基板的银纳米结构的方法,以及银纳米结构。 用于表面增强拉曼散射基板的银纳米结构体的制造方法规定了硝酸银和还原剂的浓度,混合速度,一次添加量,添加速度和总添加量等,其不能从 现有制造方法。 由此,制造的银纳米结构体具有均匀的平均尺寸,并且提供了具有非常强烈的颗粒形状的电磁场的热点,使得银纳米结构不仅可以制造成具有多聚体形状的再现性,其中SERS 信号增强,而且对于表面增强的拉曼散射基板的银纳米结构的批量生产也是有效的。 (附图标记)(AA)相对活动; (BB)加速度쨉L / s; (CC)实施例2-1〜2-10; (DD)实施例1-1〜1-10
    • 9. 发明公开
    • 반응계 외에서 생성된 금속 나노입자를 통한 핵산의 금속피복방법
    • 通过生产国外金属纳米粒子的核酸的金属化
    • KR1020030011721A
    • 2003-02-11
    • KR1020020045829
    • 2002-08-02
    • 소니 뮤직 엔터테인먼트 인터내셔널 서비시즈 게엠베하
    • 포드윌리엄이.베쎌스유리나하르낙올리버야스다아키오
    • C23C18/54B82Y30/00
    • B82Y10/00H01B1/12H01L51/0093H01L51/0595Y10S977/895
    • PURPOSE: A process for the metallisation of nucleic acids via metal nanoparticles produced ex-situ is provided which may be used, e. g., in the formation of nanowires, for electronic networks and circuits allowing a high density arrangement. CONSTITUTION: The process for the metallisation of nucleic acids comprises providing tris(hydroxymethyl)phosphine-Au(THP-Au) particles or derivatives thereof, binding the THP-Au particles to a nucleic acid to produce a metal nanoparticle-nucleic acid composite, and treatment of the metal nanoparticle-nucleic acid composite with an electroless plating solution, wherein the binding of the THP-Au particles to the nucleic acid is performed in a solution attached by one or two of its ends, immobilized on a substrate or in a semisolid state, e.g. in a gel, wherein the nucleic acid is selected from the group comprising DNA, RNA, PNA, CNA, oligonucleotides, oligonucleotides of DNA, oligonucleotides of RNA, primers, A-DNA, B-DNA, Z-DNA, polynucleotides of DNA, polynucleotides of RNA, T-junctions of nucleic acids, triplexes of nucleic acids, quadruplexes of nucleic acids, domains of non-nucleic acid polymer-nucleic acid blockcopolymers and combinations thereof, wherein the nucleic acid is double-stranded or single-stranded, wherein the binding of the THP-Au particles to the DNA is performed in a solution of water or mixed water-organic solvents, wherein the primary particle size (core diameter) is 0.5-5 nm, preferably 1-3 nm, wherein the concentration of the THP-Au particles during binding to the nucleic acid is 1 μm - 1 mm, preferably 10 μm - 0.1 mm, wherein binding is performed at a temperature 0 - 80 deg.C, preferably 20 - 50 deg.C, wherein the pH of the reaction is 2 - 10, preferably 4 - 8, and wherein a water miscible organic solvent additive is used in a concentration (volume%) 0.1-95%, preferably 1-90%.
    • 目的:提供了可以使用非金属纳米颗粒金属化核酸的方法,可以使用,例如, 例如,在形成纳米线时,用于允许高密度布置的电子网络和电路。 构成:核酸金属化的方法包括提供三(羟甲基)膦 - 金(THP-Au)颗粒或其衍生物,将THP-Au颗粒与核酸结合以产生金属纳米颗粒 - 核酸复合物,以及 用化学镀溶液处理金属纳米颗粒 - 核酸复合物,其中THP-Au颗粒与核酸的结合在固定在底物或半固体上的一个或两个末端附着的溶液中进行 状态,例如 在凝胶中,其中所述核酸选自DNA,RNA,PNA,CNA,寡核苷酸,DNA寡核苷酸,RNA寡核苷酸,引物,A-DNA,B-DNA,Z-DNA,DNA多核苷酸, RNA的多核苷酸,核酸的T连接,核酸的三重复合物,核酸的四核苷酸,非核酸聚合物 - 核酸嵌段共聚物的结构域及其组合,其中所述核酸是双链或单链的,其中 THP-Au颗粒与DNA的结合在水或混合水 - 有机溶剂的溶液中进行,其中一次粒径(芯直径)为0.5-5nm,优选1-3nm,其中浓度 在与核酸结合期间的THP-Au颗粒是1μm-1mm,优选10μm-0.1mm,其中在0-80℃,优选20-50℃的温度下进行结合,其中pH 的反应是2-10,优选4-8,并且其中水可混溶的组分 c溶剂添加剂的使用浓度(体积%)为0.1-95%,优选为1-90%。