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    • 3. 发明公开
    • Particle-optical apparatus for the irradiation of a sample
    • TeilchenoptischesGerätzur Bestrahlung einer Probe
    • EP1724809A1
    • 2006-11-22
    • EP05076151.9
    • 2005-05-18
    • FEI COMPANY
    • Knowles, Ralph W.
    • H01J37/28
    • H01J37/256H01J37/228H01J37/28H01J2237/16H01J2237/2608
    • Many particle-optical apparatus operate with a gas pressure near the sample (118) higher than in the particle-optical column. To avoid leakage into the column a pressure limiting aperture (PLA) with a small diameter is used through which the particle beam (160) leaves the column. Often there is also the need to combine the use of such a column with a path for electro-magnetic radiation, e.g. for the detection of X-rays or when a light-optical microscope is included for observation and/or navigation. Creating a path for this radiation (and optical elements thereof) typically results in an increased working distance for the column, resulting in several disadvantages. The invention offers a solution by placing a window (156) transparent to the electro-magnetic radiation but impervious to gas adjacent to the PLA (140), through which the beam of radiation (170) can enter and/or emerge from the column, to be guided and/or detected further.
    • 许多粒子光学装置在样品(118)附近的气体压力高于颗粒光学柱中操作。 为了避免泄漏到柱中,使用具有小直径的压力限制孔(PLA),粒子束(160)离开柱。 通常还需要将这种柱的使用与用于电磁辐射的路径相结合,例如, 用于检测X射线或当包含用于观察和/或导航的光学显微镜时。 为该辐射(及其光学元件)创建路径通常导致柱的工作距离增加,导致几个缺点。 本发明通过将窗口(156)放置为对电磁辐射透明但不透过与PLA(140)相邻的气体而提供了解决方案,辐射束(170)可以通过该窗口进入和/或从柱子出来, 被引导和/或进一步检测。
    • 5. 发明公开
    • LADESTATION ZUM UMLADEN VON GEFRORENEN PROBEN BEI TIEFEN TEMPERATUREN
    • LENESTATION ZUM UMLADEN VON GEFRORENEN PROBEN贝TIEFEN TEMPERATUREN
    • EP3175218A1
    • 2017-06-07
    • EP15738325.8
    • 2015-07-15
    • Leica Mikrosysteme GmbH
    • LIHL, ReinhardGAECHTER, Leander
    • G01N1/42G01N1/06G01N1/32
    • H01J37/20G01N1/06G01N1/32G01N1/42G02B21/00H01J37/18H01J37/26H01J2237/16H01J2237/20221H01J2237/262
    • The invention relates to a loading station (100, 200) for transferring a frozen sample for electron microscopy, comprising a chamber (104, 204), which is open in the upward direction and which can be at least partially filled with a coolant, wherein the chamber (104, 204) has, in a side wall thereof, at least two connections (101a, 102a, 103a) for different sample transfer devices (101, 102, 103), wherein the connections (101a, 102a, 103a) allow a frozen sample to be inserted into the chamber (104, 204) by means of a selected sample transfer device and allow a frozen sample to be removed from the chamber by means of a different sample transfer device, and wherein a receptacle (108, 208) for at least two differently designed sample holders (109, 110) is arranged in the chamber (104, 204), wherein the at least two sample holders (109, 110) can be detachably fastened to at least one of the sample transfer devices (101) in order to insert the frozen sample into the chamber (104, 204) and to remove the frozen sample from the chamber (104, 204).
    • 本发明涉及一种用于传送用于电子显微镜的冷冻样本的装载站(100,200),其包括腔室(104,204),所述腔室在向上方向上打开并且可以至少部分地填充有冷却剂,其中 腔室(104,204)在其侧壁中具有用于不同样本转移装置(101,102,103)的至少两个连接件(101a,102a,103a),其中连接件(101a,102a,103a)允许 利用选定的样本转移装置将冷冻样本插入腔室(104,204)中,并允许通过不同的样本转移装置将冷冻样本从腔室移除,并且其中容器(108,208 )至少两个不同设计的样本保持器(109,110)被布置在腔室(104,204)中,其中至少两个样本保持器(109,110)可以可拆卸地固定到至少一个样本传送装置 (101)以便将冷冻样本插入腔室(104,204)中并且t o从腔室(104,204)移除冷冻样本。
    • 7. 发明公开
    • CHARGED PARTICLE MICROSCOPE WITH BAROMETRIC PRESSURE CORRECTION
    • 带压力校正的带电粒子显微镜
    • EP3021348A1
    • 2016-05-18
    • EP15193785.1
    • 2015-11-10
    • FEI Company
    • Moers, MarcoVisscher, Albert
    • H01J37/02H01J37/26
    • H01J37/265H01J37/02H01J2237/0216H01J2237/16
    • A method of using a Charged Particle Microscope, comprising the following steps:
      - Providing a specimen on a specimen holder;
      - Directing a beam of charged particles from a source through an illuminator so as to irradiate the specimen;
      - Using a detector to detect a flux of radiation emanating from the specimen in response to said irradiation,

      particularly comprising the following steps:
      - Providing the microscope with a barometric pressure sensor;
      - Providing an automatic controller with a pressure measurement signal from said barometric pressure sensor;
      - Invoking said controller to use said signal as input to a control procedure, to compensate for a relative positional error of said beam and said specimen holder on the basis of said signal.
    • 一种使用带电粒子显微镜的方法,包括以下步骤: - 在样品架上提供样品; - 通过照明器将来自光源的带电粒子束引导以照射样品; - 使用检测器检测响应于所述照射从样本发出的辐射通量,具体包括以下步骤: - 为显微镜提供气压传感器; - 为自动控制器提供来自所述大气压力传感器的压力测量信号; - 调用所述控制器以使用所述信号作为控制过程的输入,以基于所述信号来补偿所述光束和所述样本保持器的相对位置误差。