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1. 发明公开

EP2994453A4 NOVEL HIGH PENETRATION DRUGS AND THEIR COMPOSITIONS THEREOF FOR TREATMENT OF PARKINSON DISEASES 审中-实审转让
标题翻译：新的活性高渗透及其组合物治疗帕金森氏病的治疗
公开(公告)号：EP2994453A4
公开(公告)日：2017-04-12
申请号：EP13878173
申请日：2013-03-15
申请人： TECHFIELDS PHARMA CO LTD , YU CHONGXI
发明人： YU CHONGXI , XU LINA
IPC分类号： C07C229/36 , A61K31/137 , A61K31/223 , A61P25/16 , C07C211/03 , C07C223/02
CPC分类号： C07D471/04 , A61K31/137 , A61K31/195 , A61K31/197 , A61K31/198 , A61K31/24 , A61K31/277 , A61K31/40 , C07C217/60 , C07C219/06 , C07C219/10 , C07C219/14 , C07C219/28 , C07C219/32 , C07C229/12 , C07C229/36 , C07C229/58 , C07C237/06 , C07C237/08 , C07C237/20 , C07C271/16 , C07C271/22 , C07C317/44 , C07C327/30 , C07C327/36 , C07C2602/08 , C07D207/16 , C07D211/62 , C07D321/12 , C07D455/02 , C07K5/0806 , C07K5/0823 , A61K2300/00

2. 发明授权

EP2130817B1 Polymerizable Type II photoinitiators and curable compositions 有权
标题翻译：可聚合II型光敏引发剂和可固化组合物
公开(公告)号：EP2130817B1
公开(公告)日：2016-01-06
申请号：EP08104269.9
申请日：2008-06-05
申请人： AGFA Graphics NV
发明人： Loccufier, Johan , Van Luppen, Jaymes
IPC分类号： C07D335/16 , C07C217/22 , C07C219/08 , C09D11/322 , C09D11/101 , C07C219/14
CPC分类号： C07D335/16 , C07C217/22 , C07C219/08 , C07C219/14 , C09D11/101 , C09D11/322

3. 发明公开

EP1692093A1 BIPHENYL DERIVATIVES USEFUL AS LIGANDS THAT ACTIVATE THE RAR RECEPTORS, PROCESS FOR PREPARING THEM AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS 有权
标题翻译：联苯衍生本身AS RAR受体激活配体是有用的，用于生产及其用途在人类药物及化妆品
公开(公告)号：EP1692093A1
公开(公告)日：2006-08-23
申请号：EP04804397.0
申请日：2004-12-06
申请人： Galderma Research & Development, S.N.C.
发明人： BIADATTI, Thibaud , ROYE, Olivier
IPC分类号： C07C217/18 , C07C233/18 , C07D295/08 , C07C323/25 , C07C219/14 , C07D295/18 , C07D213/80 , C07D213/79 , C07D333/38 , C07D307/68 , C07H13/08
CPC分类号： C07D213/79 , C07C217/18 , C07C219/14 , C07C233/18 , C07C235/20 , C07C235/42 , C07C323/62 , C07C2602/10 , C07D213/80 , C07D295/088 , C07D295/192 , C07D307/68 , C07D333/38
摘要： The present invention relates to novel compounds corresponding to the general formula (I) below: to compositions containing them and to their use in pharmaceutical compositions intended for use in human or veterinary medicine, or alternatively in cosmetic compositions.
摘要翻译：具有结构式（I）的新的配体的化合物：其中：式餐饮Ar为从该基团的（a）所示至（c）中选择的基团：被配制成在人或兽医学适合于给药的药物组合物，或，可替代地，进化妆品组合物。

4. 发明公开

EP1100772A1 OPEN CHAIN ALKOXYAMINE COMPOUNDS AND THEIR USE AS POLYMERIZATION REGULATORS 有权
标题翻译：伊朗伊斯兰堡ALKOXYAMINVERBINDUNGEN公司ANWENDUNG ALS POLYMERISATIONSREGLER
公开(公告)号：EP1100772A1
公开(公告)日：2001-05-23
申请号：EP99939409.1
申请日：1999-07-27
申请人： Ciba Specialty Chemicals Holding Inc.
发明人： NESVADBA, Peter , KRAMER, Andreas , ZINK, Marie-Odile , LAZZARI, Dario
IPC分类号： C07C239/18 , C07C239/20 , C07C239/12 , C07C239/16 , C08F291/00
CPC分类号： C08L53/00 , C07C219/06 , C07C219/14 , C07C237/06 , C07C237/24 , C07C239/12 , C07C239/18 , C07C239/20 , C07C255/16 , C07C255/46 , C07C291/04 , C07C2601/08 , C07C2601/14 , C07D309/12 , C08F291/00 , C08F293/005 , C08L51/003 , C09J151/00 , C09J153/00
摘要： The invention relates to a compound of formula (Ia), (Ib) or (Ic). The open chain alkoxyamine compounds are useful for the polymerization of ethylenically unsaturated monomers. The compounds of the present invention provide polymeric resin products having low polydispersity. The polymerization process proceeds with enhanced monomer to polymer conversion efficiency. In particular, this invention relates to stable free radical-mediated polymerization processes which provide homopolymers, random copolymers, block copolymers, multiblock copolymers, graft copolymers and the like, at enhanced rates of polymerization and enhanced monomer to polymer conversions.
摘要翻译：本发明涉及式Ia，Ib或Ic的化合物。开链烷氧基胺化合物可用于烯属不饱和单体的聚合。本发明的化合物提供具有低多分散性的聚合物树脂产品。聚合过程由单体转化为聚合物转化效率提高。特别地，本发明涉及稳定的自由基介导的聚合方法，其提供均聚物，无规共聚物，嵌段共聚物，多嵌段共聚物，接枝共聚物等，以提高聚合速率和增强的单体与聚合物转化率。

5. 发明公开

EP0937030A4 3-AMINO-PROPOXYPHENYL DERIVATIVES (I) 失效
标题翻译： 3- AMINOPROPOXYPHENYL衍
公开(公告)号：EP0937030A4
公开(公告)日：2000-06-07
申请号：EP96932390
申请日：1996-10-10
申请人： UNIV MELBOURNE
发明人： LOUIS WILLIAM JOHN , JACKMAN GRAHAM PAUL , IAKOVIDIS DIMITRIOS , LOUIS SIMON NICHOLAS STEWART , DRUMMER OLAF HEINO
IPC分类号： A61P9/06 , A61K31/135 , A61K31/137 , A61K31/138 , A61K31/275 , A61K31/277 , A61P9/10 , A61P27/06 , C07C217/30 , C07C217/34 , C07C217/60 , C07C219/04 , C07C219/06 , C07C219/12 , C07C219/14 , C07C255/54
CPC分类号： A61K31/137 , A61K31/277 , C07C217/34 , C07C217/60 , C07C219/06 , C07C219/12 , C07C219/14 , C07C255/54 , C07C2601/02

6. 发明公开

EP0937030A1 3-AMINO-PROPOXYPHENYL DERIVATIVES (I) 失效
标题翻译： 3-氨基 - 丙氧基苯基衍生物（I）
公开(公告)号：EP0937030A1
公开(公告)日：1999-08-25
申请号：EP96932390.0
申请日：1996-10-10
申请人： THE UNIVERSITY OF MELBOURNE
发明人： LOUIS, William, John , JACKMAN, Graham, Paul , IAKOVIDIS, Dimitrios , LOUIS, Simon, Nicholas, Stewart , DRUMMER, Olaf, Heino
IPC分类号： A61P9 , A61K31 , A61P27 , C07C217 , C07C219 , C07C255
CPC分类号： A61K31/137 , A61K31/277 , C07C217/34 , C07C217/60 , C07C219/06 , C07C219/12 , C07C219/14 , C07C255/54 , C07C2601/02
摘要： Compounds of formula (Ia) as potent, β1-specific beta blockers with a short duration of action in the systemic circulation, wherein R is 3',4'-dimethoxyphenyl, R1 is hydrogen, and R2 is selected from methyl, ethyl, propyl, isobutyl and isopropyl; or R is 3',4'-dimethoxyphenyl, R1 is selected from fluorine, chlorine and bromine, and R2 is selected from methyl, ethyl, propyl, isopropyl, isobutyl and cyclopropylmethyl; or R is 4'-methoxyphenoxy, R1 is selected from hydrogen, fluorine, chlorine and bromine, and R2 is selected from methyl, ethyl, propyl, isopropyl, isobutyl and cyclopropylmethyl; or R is 3',4'-dimethoxyphenyl, R1 is cyano, and R2 is cyclopropylmethyl; or R is 4'-methoxyphenoxy, R1 is cyano, and R2 is isobutyl; and physiologically acceptable hydrolysable derivatives thereof having the hydroxy group in the 2-position of the 3-aminopropoxy side chain in esterified form, in their racemic and optically active forms, and their pharmaceutically acceptable acid addition salts.
摘要翻译：式（Ia）化合物作为在体循环中作用时间短的有效的β1特异性β阻滞剂，其中R是3'，4'-二甲氧基苯基，R1是氢，并且R2选自甲基，乙基，丙基，异丁基和异丙基; 或R是3'，4'-二甲氧基苯基，R1选自氟，氯和溴，R2选自甲基，乙基，丙基，异丙基，异丁基和环丙基甲基; 或R是4'-甲氧基苯氧基，R 1选自氢，氟，氯和溴，并且R 2选自甲基，乙基，丙基，异丙基，异丁基和环丙基甲基; 或R是3'，4'-二甲氧基苯基，R1是氰基，R2是环丙基甲基; 或者R是4'-甲氧基苯氧基，R1是氰基，R2是异丁基; 及其酯化形式的3-氨基丙氧基侧链的2-位羟基以其外消旋形式和旋光形式及其药学上可接受的酸加成盐的生理上可接受的可水解衍生物。

7. 发明公开

EP0664788A1 SUBSTITUIERTE ETHANOLAMINESTER 失效
标题翻译： SUBSTITUIERTE ETHANOLAMINESTER。
公开(公告)号：EP0664788A1
公开(公告)日：1995-08-02
申请号：EP93923482.0
申请日：1993-10-18
申请人： Byk Nederland BV
发明人： BRON, Jan , STERK, Geert, Jan , TIMMERMAN, Hendrik , VEERMAN, Meta, E., J. , VAN DER WERF, Jan, Fetze
IPC分类号： C07D213 , A61K31 , A61P11 , A61P25 , C07C219 , C07C229 , C07C255 , C07C317 , C07C327 , C07D209 , C07D319 , C07D333
CPC分类号： C07C229/14 , C07C219/06 , C07C219/10 , C07C219/14 , C07C219/18 , C07C255/50 , C07C317/44 , C07C327/30 , C07C2601/14 , C07C2602/08 , C07D209/18 , C07D213/55 , C07D319/20 , C07D333/16
摘要： The invention concerns compounds of the formula (I): Ar1-CH(OH)-CH2-NH-CH2-X-CH2-E-(CH2)n-Y-Ar2, in which the substituents and the symbols are as defined in the description. Such compounds are active substances with, in particular, a broncholytic action.
摘要翻译： PCT No.PCT / EP93 / 02862 Sec。 371日期1995年04月17日 102（e）日期1995年4月17日PCT 1993年10月18日PCT PCT。出版物WO94 / 08945 日期1994年4月28日式（I）化合物：Ar1-CH（OH）-CH2-NH-CH2-X-CH2-E-（CH2）nY-Ar2，其中取代基和符号具有描述是具有特别是支气管分解作用的新型活性化合物。

8. 发明公开

EP0426217A3 Bleach precursors 失效
标题翻译：漂白的前辈
公开(公告)号：EP0426217A3
公开(公告)日：1992-03-04
申请号：EP90202657.4
申请日：1990-10-05
申请人： UNILEVER N.V. , UNILEVER PLC
发明人： Madison, Stephen Alan , Lam, Pamela Chau
IPC分类号： C07C309/42 , C07C409/24 , C11D3/39
CPC分类号： C11D3/3907 , C07C219/06 , C07C219/14 , C07C309/42 , C07C409/24 , C07C409/30
摘要： A bleach precursor compound, its peroxygen derivative, and detergent compositions containing these materials are disclosed herein. The bleach precursors structurally comprise a pair of different diesters, one ester containing an electrically-charged functional group. Perhydrolysis of the precursor in the presence of hydrogen peroxide and a basic aqueous medium generates a peroxycarboxylic acid.

9. 发明公开

EP3124114A1 TRANSESTERIFICATION REACTION BY MEANS OF IRON CATALYST 审中-公开
标题翻译： UMESTERUNGSREAKIT MITTELS EISENKATALYSATOR
公开(公告)号：EP3124114A1
公开(公告)日：2017-02-01
申请号：EP15768790.6
申请日：2015-02-03
申请人： Kyushu University, National University Corporation
发明人： OHSHIMA Takashi , YAZAKI Ryo , FUJIMOTO Chika , HORIKAWA Rikiya
IPC分类号： B01J31/22 , C07C67/03 , C07C69/612 , C07C69/618 , C07C69/78 , C07B61/00
CPC分类号： C07C213/06 , B01J23/745 , B01J31/22 , C07B41/12 , C07B2200/07 , C07C67/03 , C07C67/08 , C07C231/02 , C07C269/06 , C07C2601/14 , C07C2603/74 , C07D211/22 , C07D211/46 , C07C69/78 , C07C69/612 , C07C69/618 , C07C69/34 , C07C233/65 , C07C233/75 , C07C233/11 , C07C271/22 , C07C219/14 , C07C219/24 , C07C219/34
摘要： Provided is a catalyst for transesterification reactions, which contains an iron salen complex. Also provided is a method for producing an ester compound, which is characterized by carrying out a transesterification reaction between a starting material ester and a starting material alcohol with use of the catalyst.
摘要翻译：提供了含有铁盐配合物的酯交换反应的催化剂。还提供了一种酯化合物的制造方法，其特征在于使用催化剂进行原料酯与起始原料醇的酯交换反应。

10. 发明公开

EP2041108A1 4-HYDROXYTHIOBENZAMIDE DERIVATIVES OF DRUGS 有权
标题翻译：药物4-羟基苯甲酰胺衍生物
公开(公告)号：EP2041108A1
公开(公告)日：2009-04-01
申请号：EP07763921.9
申请日：2007-07-18
申请人： Antibe Therapeutics Inc.
发明人： WALLACE, John L. , CIRINO, Giuseppe , SANTAGADA, Vincenzo , CALIENDO, Giuseppe
IPC分类号： C07D309/30 , C07C327/48
CPC分类号： C07C327/48 , C07C219/14 , C07D209/18 , C07D209/32 , C07D309/30 , C07D339/04 , C07D409/12
摘要： Derivatives of drugs are provided, said derivatives comprising the H2S-releasing moiety 4-hydroxythiobenzamide that is either covalently linked to the drug or forms a salt with the drug. The compounds of the present invention exhibit enhanced activity or reduced side effects or both.
摘要翻译：提供了药物衍生物，所述衍生物包含H2S释放部分4-羟基硫代苯甲酰胺，其与药物共价连接或与药物形成盐。本发明的化合物表现出增强的活性或降低的副作用或两者。

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