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1. 发明公开

EP3017307A1 3-ARYL PROPIOLONITRILE COMPOUNDS FOR THIOL LABELING 审中-公开
标题翻译：用于硫醇标记的3-芳基丙酮化合物
公开(公告)号：EP3017307A1
公开(公告)日：2016-05-11
申请号：EP14739728.5
申请日：2014-07-04
申请人： Université de Strasbourg , Centre National de la Recherche Scientifique
发明人： WAGNER, Alain , KONIEV, Oleksandr
IPC分类号： G01N33/58 , G01N33/84 , C07K1/13 , C07C255/44 , C07C323/60 , C07D207/404 , C07C255/35 , C07C255/37 , C07C255/41 , C07C255/42 , C07F9/50
CPC分类号： C07C255/43 , C07B2200/05 , C07C255/34 , C07C255/35 , C07C255/37 , C07C255/41 , C07C255/42 , C07C255/44 , C07C271/16 , C07C271/22 , C07C271/28 , C07C275/42 , C07C309/42 , C07C319/02 , C07C323/42 , C07C323/60 , C07C331/28 , C07C335/22 , C07C2602/24 , C07D207/452 , C07D207/46 , C07D249/06 , C07D265/38 , C07D311/82 , C07D311/88 , C07D337/04 , C07D403/12 , C07D405/12 , C07D409/12 , C07D495/04 , C07F5/04 , C07F7/08 , C07F7/081 , C07F9/5442 , C07K1/13 , C07K14/70596 , C07K16/2863 , C07K16/30 , C07K16/32 , C07K19/00 , C07K2317/24 , C07K2317/76 , C12N9/2462 , C12Y302/01017 , G01N33/58 , G01N33/84
摘要： The present invention relates to a process for labeling compounds comprising thiol moieties with 3-arylpropiolonitrile compounds, to 3-arylpropiolonitrile compounds substituted with tag moieties and to specific 3-arylpropiolonitrile linkers.
摘要翻译：本发明涉及用3-芳基丙炔腈化合物标记包含硫醇部分的化合物，用标记部分取代的3-芳基丙炔腈化合物和特定的3-芳基丙炔腈接头的方法。

2. 发明授权

EP1536285B1 Photosensitive composition, compound for use in the photosensitive composition, and pattern forming method using the photosensitive composition 有权
标题翻译：感光性组合物，化合物在该组合物中使用，和使用这样的组合物的图像记录方法
公开(公告)号：EP1536285B1
公开(公告)日：2016-01-06
申请号：EP04027406.0
申请日：2004-11-18
申请人： FUJIFILM Corporation
发明人： Wada, Kenji , Kodama, Kunihiko
IPC分类号： G03F7/004 , G03F7/038 , G03F7/039 , G03F7/075 , G03F7/20 , C07C309/42 , C07C309/39 , C07C323/66 , C07C381/12
CPC分类号： C07C381/12 , C07C309/39 , C07C309/42 , C07C323/66 , G03F7/0045 , G03F7/0046 , G03F7/0382 , G03F7/0392 , G03F7/0395 , G03F7/0397 , G03F7/0758 , G03F7/2041 , Y10S430/106 , Y10S430/111 , Y10S430/122

3. 发明公开

EP2825523A1 NOVEL SULFONATE-BASED TRIMEBUTINE SALTS 审中-公开
标题翻译：基于磺酸盐新型TRIMEBUTINSALZE
公开(公告)号：EP2825523A1
公开(公告)日：2015-01-21
申请号：EP13761968.0
申请日：2013-03-11
申请人： Gicare Pharma Inc.
发明人： MEUNIER, Jean-François , LAU, Cheuk Kun , GUAY, Daniel , BYDLINSKI, Gregory , SPASSOVA, Nadejda , CANTIN, Louis-David , RANGER, Maxime
IPC分类号： C07C219/22 , A61K31/185 , A61K31/277 , A61K31/426 , A61K31/4402 , A61K31/4406 , A61P29/00 , C07C309/03 , C07C309/28 , C07C327/48 , C07D213/71 , C07D277/36
CPC分类号： C07C229/38 , A61K9/1652 , A61K9/2054 , C07C219/22 , C07C309/04 , C07C309/08 , C07C309/30 , C07C309/39 , C07C309/42 , C07C309/46 , C07C309/58 , C07C309/59 , C07C327/48 , C07D213/71 , C07D277/36
摘要： The present description relates to compounds of Formula I (A
+ X
- ), a diastereoisomer, an enantiomer, or a mixture thereof, pharmaceutical composition comprising same and uses thereof for gastrointestinal endoscopic and medical imaging applications, and for the treatment of visceral pain: Where R
1 and R
2 are as defined herein

4. 发明公开

EP2620145A3 2,5-dihydroxybenzene compounds for the treatment of of cancer of an organ 审中-公开
标题翻译： Verwendung von 2,5-Dihydroxybenzen-Verbindungen zur Behandlung von Krebs eines Organs
公开(公告)号：EP2620145A3
公开(公告)日：2014-01-08
申请号：EP12174180.5
申请日：2007-08-15
申请人： Action Medicines, S.L.
发明人： Cuevas Sánchez, Pedro , Giménez Gallego, Guillermo , Sáenz De Tejada Gorman, Iñigo , Angulo Frutos, Javier , Lozano Puerto, Rosa María , Romero Garrido, Antonio , Valverde López, Serafín
IPC分类号： A61K31/185 , A61K31/192 , A61K31/222 , A61K31/216 , A61K31/255 , A61P43/00 , A61K45/06
CPC分类号： A61K31/255 , A61K9/0014 , A61K31/095 , A61K31/10 , A61K31/185 , A61K31/192 , A61K31/216 , A61K31/222 , A61K31/225 , A61K31/235 , A61K45/06 , C07C57/44 , C07C59/68 , C07C65/03 , C07C65/19 , C07C69/017 , C07C69/84 , C07C309/24 , C07C309/42 , C07C309/68 , C07C309/75 , A61K2300/00
摘要： The present invention refers to the use of a compound of Formula (I") or pharmaceutically acceptable salt or solvate, isomer or prodrug thereof in the manufacturing of a medicament for the treatment and/or prophylaxis of cancer of an organ.
摘要翻译：本发明涉及式（I“）化合物或其药学上可接受的盐或溶剂合物，异构体或前药在制备用于治疗和/或预防器官癌症的药物中的用途。

5. 发明公开

EP1847563A2 Antistatic and antidust agents, compositions thereof, and methods of manufacture 审中-公开
标题翻译：抗静电和防污化合物，它们的组合物以及制备方法
公开(公告)号：EP1847563A2
公开(公告)日：2007-10-24
申请号：EP07112780.7
申请日：2003-06-24
申请人： General Electric Company
发明人： Chowdhury, Sanjoy Kumar , Wadgaonkar, Prakash Purushottam , Hoeks, Theodorus Lambertus , Scholten, Alex Bernard , Rajaraman, Suresh K. , Sarwade, Bhimrao D. , Avadhani, Chilukuri Ver
IPC分类号： C08K5/00
CPC分类号： C07C303/32 , C08K5/0075 , C08K5/42 , C08L69/00 , C07C309/42
摘要： A quaternary onium aromatic sulfonate represented by the formula:

wherein each R 1 independently comprises substituted or unsubstituted, aliphatic or aromatic, hydrocarbyl, carbocyclic or heterocyclic radicals, each X is selected from the group consisting of phosphorus and nitrogen; wherein "a" has a value of 0, 1 or 2, and "b" has a value of 0 or 1 with the proviso that (a + b) is equal to 1 or 2; G 1 is an aromatic group; E comprises a bis(carbonyloxyalkyl) polydiorganosiloxane, a bis(carbonyloxyaryl) polydiorganosiloxane, and an ether linkage; each Y 1 independently comprises hydrogen, a monovalent hydrocarbon group, alkenyl, allyl, halogen, bromine, chlorine; nitro; and OR, wherein R is a monovalent hydrocarbon group; "q" represents any integer from and including zero through the number of positions on G' available for substitution; "t" represents an integer equal to at least one; "s" represents an integer equal to either zero or one; and "u" represents any integer including zero; with the proviso that when E is an ether linkage, then X is phosphorus.
摘要翻译：由下式表示的季鎓芳族磺酸盐：worin每个R1unabhängig包括substituiertem奥德unsubstituiertem，脂肪族或芳香族，烃基，碳环或杂环基团，每个X选自磷和氮中选择的; worin “一” 具有0,1或2的值，和 “b” 具有的值为0或1，条件做了（A + B）是等于1或2; 克1-是芳族基团; E包括双（carbonyloxyalkyl）聚二有机硅氧烷，聚二有机硅氧烷二（carbonyloxyaryl），并在醚键; 每个Y 1独立地包括氢，一价烃基，烯基，烯丙基，卤素，溴，氯; 硝基; 和OR，worin R是单价烃基; “Q” darstellt从通过位置对G“可用于取代的数量的任何整数，并且包括零; “T” darstellt整数等于至少一个; “S” darstellt整数等于零或任一个; 和“u” darstellt任何整数包括零; 其条件做了当E是醚键，则X是磷。

6. 发明公开

EP1536285A3 Photosensitive composition, compound for use in the photosensitive composition, and pattern forming method using the photosensitive composition 有权
标题翻译：感光性组合物，化合物在该组合物中使用，和使用这样的组合物的图像记录方法
公开(公告)号：EP1536285A3
公开(公告)日：2007-07-25
申请号：EP04027406.0
申请日：2004-11-18
申请人： FUJIFILM Corporation
发明人： Wada, Kenji , Kodama, Kunihiko
IPC分类号： G03F7/004 , G03F7/039 , G03F7/038
CPC分类号： C07C381/12 , C07C309/39 , C07C309/42 , C07C323/66 , G03F7/0045 , G03F7/0046 , G03F7/0382 , G03F7/0392 , G03F7/0395 , G03F7/0397 , G03F7/0758 , G03F7/2041 , Y10S430/106 , Y10S430/111 , Y10S430/122
摘要： A photosensitive composition comprising a compound capable of generating a specific sulfonic acid upon irradiation with actinic rays or a radiation; a compound capable of generating a specific sulfonic acid upon irradiation with an actinic ray or a radiation; and a pattern forming method using a photosensitive composition comprising a compound capable of generating a specific sulfonic acid upon irradiation with an actinic ray or a radiation.

7. 发明公开

EP1736464A1 QUATERNARY AMMONIUM COMPOUND, PROCESS FOR PRODUCING THE SAME, THERAPEUTIC AGENT FOR CEREBROVASCULAR DISORDER, AND THERAPEUTIC AGENT FOR HEART DISEASE 审中-公开
标题翻译：季铵化合物; 方法进行生产，治疗剂AGAINST脑血管疾病和治疗剂预防心脏病
公开(公告)号：EP1736464A1
公开(公告)日：2006-12-27
申请号：EP05727867.3
申请日：2005-03-29
申请人： Dainippon Ink and Chemicals, Incorporated
发明人： TAKAGAKI, Hidetsugu , SANO, Yoshiyuki , KATAKAMI, Yasuyuki , MIYAMOTO, Masanori
IPC分类号： C07C217/18 , A61K31/205 , A61P9/10 , C07C213/00 , C07C309/42
CPC分类号： C07C217/22 , A61K31/205 , C07C309/42
摘要： A quaternary ammonium compound of the present invention is a quaternary ammonium compound represented by general formula (I) or (I')

(wherein, A represents a linear alkyl group having 1 to 4 carbon atoms, a branched alkyl group having 2 to 4 carbon atoms, a linear alkyl group having 1 to 4 carbon atoms and a hydroxyl group, or a branched alkyl group having 2 to 4 carbon atoms and a hydroxyl group, R 1 to R 3 may be the same or different and represent a linear or branched alkyl group having 1 to 12 carbon atoms, one of R 4 to R 8 represents CO 2 - or SO 3 - , while no more than three of the remaining R 4 to R 8 represent a group selected from the group consisting of a hydroxyl group and an alkoxy group having 1 to 4 carbon atoms, and other R 4 to R 8 represent a hydrogen atom, one of R' 4 to R' 8 represents CO 2 H or SO 3 H, no more than three of the remaining R' 4 to R' 8 represent a group selected from a protected hydroxyl group and an alkoxy group having 1 to 4 carbon atoms, while other R' 4 to R' 8 represent a hydrogen atom, and X - represents an anion capable of forming a salt with a quaternary ammonium group).
摘要翻译：本发明的季铵化合物为季铵化合物由通式（I）或（I“）表示（worin，A darstellt具有1至4个碳原子，具有2至4个碳的支链烷基的直链烷基原子，具有1至4个碳原子和羟基，或具有2-4个碳原子和羟基基团，R 1至R 3的支链状烷基的直链烷基可以是相同或不同，表示直链或支链的烷基具有1至12个碳原子，R 4中的一个至R 8 darstellt CO 2 - 或SO 3 - ，而不超过三个其余的R 4至R 8表示选自以下的基团选自羟基的并且在具有1至4个碳原子的烷氧基，和其它的R 4至R 8表示氢原子，不超过三个剩余的R的R“4至R” 8 darstellt CO 2 H或SO 3 H，其中一个“ 4至R“8表示从被保护的羟基基团和具有1至4个碳原子的烷氧基中的基团，而OT 前R“4至R” 8表示氢原子，X - darstellt阴离子的能够形成季铵基盐的）。

8. 发明公开

EP1587477A2 ODORLESS FORMULATION FOR TREATING MUCOSAL DISCONTINUITIES 有权
标题翻译：无嗅配方治疗粘膜不连续性
公开(公告)号：EP1587477A2
公开(公告)日：2005-10-26
申请号：EP04700231.6
申请日：2004-01-05
申请人： Epien Medical, Inc.
发明人： BASARA, Michael
IPC分类号： A61K6/00
CPC分类号： A61Q19/10 , A61K8/466 , A61K31/185 , A61K31/255 , A61K45/06 , A61K2800/28 , A61Q11/00 , A61Q19/00 , C07C303/06 , C07C303/32 , C07C309/42 , A61K2300/00
摘要： The present invention includes a method for making a formulation for treating mucosal discontinuities, comprising: providing phenolic compounds and treating the purified phenolic compounds with sulfuric acid to make sulfonic acids and sulfonate salts. The present invention also includes formulations prepared by the method.
摘要翻译：本发明包括制备用于治疗粘膜不连续性的制剂的方法，包括：提供酚类化合物并用硫酸处理纯化的酚类化合物以制备磺酸和磺酸盐。本发明还包括通过该方法制备的制剂。

9. 发明公开

EP1568788A2 Aromatische Sulfonsäuren, ihr Herstellungsverfahren, ihre Aldehydkondensate und ihre Verwendung im Leder-, Papier- und Textilbereich 审中-公开
标题翻译：芳香族磺酸，它们的制备方法，其醛缩合物以及它们在皮革，造纸和纺织行业的应用
公开(公告)号：EP1568788A2
公开(公告)日：2005-08-31
申请号：EP05003622.7
申请日：2005-02-19
申请人： LANXESS Deutschland GmbH
发明人： Brinkmann, Nils, Dr. , Kleban, Martin, Dr. , Markgraf, Kirsten, Dr.
IPC分类号： C14C3/22 , C07C309/34
CPC分类号： C07C309/43 , C07C309/42 , C07C2602/08 , C07D311/74 , C14C3/20
摘要： Aromatische Hydroxysulfonate der Formel I
ihr Herstellungsverfahren, ihre Aldehydkondensate und ihr Verwendung im Leder-, Papier- und Textilbereich.
摘要翻译：羟基芳族磺酸化合物是新的。式（I）的羟基芳族磺酸都是新的。 X和Y：式-R 3的基团>的R 5> C-CR 4>，R 5> - （Ia）的; ，R 3>，R 5> C = C-R 4>（IB）; 且R 1> - ，R 6>为H，烷基（特别是任选substituiertem 1-4C烷基）或芳基（特别是任意取代的苯基），其中R 2中的至少一个> - ，R 5> = OH取代的芳基任选地被磺基Ñsubstituiertem 基团，特别是爱所有羟基苯其任选磺化和R 5>和R 6>因此可以是OH; ，R 7>或H OPTIONALLY磺化对 - 羟基苯基; 米：0-3; n和p：0-4，其中m + N + P> = 1（特别是1.8-3.2）; 和q：0或1，独立权利要求中包含的，因此对（1）制备的羟基磺酸和/或羟基磺酸盐; （2）的4种不同的化合物（I）与磺化苯酚（0.5-20重量％），磺化4,4-异亚丙基（10-50重量％）和磺化邻 - [1-（4-羟基苯基混合物）-1-甲基乙基]苯酚（5-40重量％）。和（3）脂族醛（尤其是甲醛）基于上述羟基磺酸或它们的混合物的缩合物。 [图像]。

10. 发明授权

EP1286958B1 IMPROVED PURIFICATION OF PHENYL ESTER SALTS 有权
标题翻译：清洁苯基酯
公开(公告)号：EP1286958B1
公开(公告)日：2005-01-12
申请号：EP01944282.1
申请日：2001-06-04
申请人： EASTMAN CHEMICAL COMPANY , The Procter & Gamble Company
发明人： ARUMUGAM, Bhaskar, K. , BYMASTER, Dimmick, L. , EAGAN, Robert, L. c/o Eastman Chem. Company , ECKART, Edward, J. , FELTY, Jarvey, E. , FONTENOT, Kevin, J. c/o Eastman Chem. Company , GREEN, Jeffrey, W. , KIRK, Shane, K. , LUTZ, Gary P. , SANDER, Tony, L. c/o Eastman Chemical Company , WILLIAMS, Thomas, H. , ZIMA, George C. , DUPONT, Jeffrey, Scott , DYKSTRA, Robert, Richard , BURNS, Michael, Eugene
IPC分类号： C07C303/44 , C07C309/42
CPC分类号： C07C303/44 , C07C309/42
摘要： The invention relates to a process for purifying and decolorizing a phenyl ester salt. The process combines a phenyl ester salt with a solvent to form a mixture and then stirs the mixture to form a slurry. The phenyl ester salt is substantially insoluble in this solvent. The process then collects the phenyl ester salt from the slurry. The collected phenyl ester salt may then be optionally dried or recrystallized. The collected phenyl ester salt is dissolved in a solvent to form a solution. The solution is decolorized and then spray dried to form a powder of the phenyl ester salt. As a result of the process the phenyl ester salt powder has a higher purity and an improved color as compared to the starting phenyl ester salt.

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