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    • 3. 发明公开
    • ENDOVASCULAR TREATMENT AID
    • EP3141213A4
    • 2018-01-10
    • EP15789105
    • 2015-05-08
    • TORAY INDUSTRIESINOUE KANJI
    • INOUE KANJIYAGI TAKAHIROFUJITA MASAKIKADOWAKI KOJITANAHASHI KAZUHIRO
    • A61F2/01
    • A61F2/013A61F2/01A61F2002/011A61F2002/016A61F2230/0067A61F2250/0098
    • An endovascular treatment aiding device with which adhesion of the endovascular treatment aiding device to a blood vessel can be confirmed, and which can prevent leakage of a captured substance, is disclosed. The endovascular treatment aiding device is an endovascular treatment aiding device comprising: a flexible shaft; a filter fixed to the shaft such that an opening section is formed in the proximal side, wherein a ring having elastic restoring force is fixed to the opening section, which filter is capable of being opened and closed in an umbrella-like manner, and is in a conical shape having a bottom formed by the ring when the filter is open; and a linear supporting member fixed to the ring and a part of the shaft such that these are connected to each other, which linear supporting member enables to close the filter by application of an external force to the proximal side; wherein coils formed with a radio-opaque material is/are wound around the ring; when the filter is closed, a plurality of mountains pointing toward the distal side and a plurality of valleys pointing toward the proximal side are alternately formed in the ring to form a shape in which the mountains are positioned close to each other, and the valleys are positioned close to each other; and the coils are arranged on the ring such that the coils contain the positions fixed by the supporting member on the ring, but do/does not contain the positions of the peaks of the mountains and the peaks of the valleys.
    • 9. 发明公开
    • ANTITHROMBOTIC MATERIAL
    • 抗血小板药物
    • EP3078389A4
    • 2017-08-09
    • EP14866413
    • 2014-11-27
    • TORAY INDUSTRIES
    • KADOWAKI KOJIFUJITA MASAKISAKAGUCHI YUKATANAHASHI KAZUHIRO
    • A61L33/10
    • A61L33/0041A61L33/0076
    • The present invention aims to provide an antithrombogenic material which is highly safe with its low hemolytic toxicity, and capable of maintaining high antithrombogenicity for a long period. The present invention provides an antithrombogenic material comprising: a coating material containing a polymer containing, as a constituent monomer, a compound selected from the group consisting of alkyleneimines, vinylamines, allylamines, lysine, protamine, and diallyldimethylammonium chloride, and an anionic compound containing a sulfur atom and having anticoagulant activity; and a base material whose surface is coated with the coating material; wherein the polymer is covalently bound to the base material, and the abundance ratio of nitrogen atoms to the abundance of total atoms as measured by X-ray photoelectron spectroscopy on the surface is 6.0 to 12.0 atomic percent.
    • 本发明的目的在于提供一种溶血性毒性低,安全性高,能长期维持高抗血栓性的抗血栓形成物质。 本发明提供一种抗血栓形成性材料,其包含:包含含有选自由亚烷基亚胺,乙烯基胺,烯丙基胺,赖氨酸,鱼精蛋白和二烯丙基二甲基氯化铵组成的组中的化合物作为构成单体的聚合物的涂布材料和含有 硫原子并具有抗凝血活性; 以及其表面涂覆有涂层材料的基材; 其中所述聚合物共价结合于所述基材,并且通过所述表面上的X射线光电子能谱法测量的氮原子与全部原子的丰度的存在比率为6.0至12.0原子百分比。