专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明公开

EP2990010A4 ARTIFICIAL BLOOD VESSEL 有权
标题翻译：人造血血管
公开(公告)号：EP2990010A4
公开(公告)日：2016-11-30
申请号：EP14788777
申请日：2014-04-23
申请人： TORAY INDUSTRIES
发明人： YAMADA SATOSHI , TSUCHIKURA HIROSHI , TANAKA NOBUAKI , TANAHASHI KAZUHIRO , SAKAGUCHI YUKA , FUJITA MASAKI , KADOWAKI KOJI
IPC分类号： A61F2/06 , A61L27/18 , A61L33/06 , D04B21/02
CPC分类号： A61F2/89 , A61F2/06 , A61F2210/0076 , A61F2250/0017 , A61F2250/0067 , A61L27/18 , A61L33/068 , D04B21/02 , D10B2509/06 , C08L79/02
摘要： The present invention addresses the problem of providing an artificial blood vessel which is able to retain mechanical properties required for an artificial blood vessel, rarely undergoes the formation of thrombi when grafted into a blood vessel having a small or medium diameter, and has such an excellent cell colonization property that endothelial cells can be colonized rapidly to form an endothelial tissue. Thus, the present invention provides an artificial blood vessel comprising a tubular woven fabric which is composed of at least two types of polyester fibers, i.e., a multifilament yarn A and a multifilament yarn B, and has an inner diameter of 8 mm or less and a layer thickness of 50 µm or more and 250 µm or less, wherein the multifilament yarn A has a single fiber fineness of 1.0 dtex or more and a total fineness of 33 dtex or less, the multifilament yarn B has a single fiber fineness of 0.08 dtex or less and a total fineness of 66 dtex or less, and the multifilament yarn B forms loops on the inner wall surface of the composite tubular woven fabric.

2. 发明公开

EP3181093A4 ARTIFICIAL BLOOD VESSEL 审中-公开
公开(公告)号：EP3181093A4
公开(公告)日：2018-07-18
申请号：EP15831273
申请日：2015-06-17
申请人： TORAY INDUSTRIES
发明人： TSUCHIKURA HIROSHI , YAMADA SATOSHI , KANEKO TAKAYUKI , KUWABARA ATSUSHI , SAKAGUCHI YUKA , KADOWAKI KOJI , TAKAOKA MOTOKI
IPC分类号： A61F2/06 , D03D3/02 , D03D11/00
CPC分类号： A61F2/06 , A61F2210/0076 , A61L27/18 , A61L27/507 , D03D3/02 , D03D11/00 , D10B2331/04 , D10B2509/06 , C08L67/02 , C08L75/04
摘要： Provided is a textile vascular prosthesis having various properties required of it and having a repair function that is similar to that of blood vessels in a living body and relies on spontaneous healing ability of a human body. The inner layer-covering rate C (%) is defined by the formula: C = W 1 × D 1 + W 2 × D 2 × 25.4 ˆ’ W 1 × W 2 × D 1 × D 2 / 25.4 × 25.4 × 100 , where D1 is the warp density (ends/25.4 mm) of an outer layer, D2 is the weft density (picks/25.4 mm) of the outer layer, W1 is the apparent width (mm) of a warp yarn of the outer layer, and W2 is the apparent width (mm) of a weft yarn of the outer layer. The inner layer-covering rate C (%), representing the coverage of an inner layer formed of warp yarn 3 and weft yarn 4 by the outer layer formed of warp yarn 1 and weft yarn 2, is 15% ‰¤ C ‰¤ 75%.

3. 发明公开

EP3141191A4 ENDOVASCULAR TREATMENT ASSISTANCE TOOL 审中-公开
公开(公告)号：EP3141191A4
公开(公告)日：2018-04-04
申请号：EP15788802
申请日：2015-05-08
申请人： TORAY INDUSTRIES , INOUE KANJI
发明人： INOUE KANJI , YAGI TAKAHIRO , FUJITA MASAKI , KADOWAKI KOJI , TANAHASHI KAZUHIRO
IPC分类号： A61F2/01 , A61L33/00
CPC分类号： A61F2/013 , A61B17/00 , A61F2002/011 , A61F2002/015 , A61F2002/016 , A61F2230/0067 , A61F2230/0069 , A61F2230/0093 , A61L33/0035
摘要： An endovascular treatment aiding device whose filter is not caught by a treatment device during retrieval of the endovascular treatment aiding device is disclosed. The treatment aiding device comprises: a flexible shaft; a filter fixed to the shaft, which can be opened and closed in an umbrella-like manner; linear supporting members each of which connects the end portion in the opening-section side of the filter to a part of the shaft such that the filter can be closed by applying an external force to the proximal side; an elastomer member composed of an elastomer in which a penetrating hole (A) is formed, which elastomer member is arranged in the proximal side relative to the opening section of the filter such that the shaft penetrates the penetrating hole (A), wherein the outer diameter of the end face in which the penetrating hole (A) is formed is larger than the outer diameter of the opening-section side of the filter when the filter is closed; and an outer tube in which a penetrating hole (B) is formed, which outer tube is arranged in the proximal side relative to the opening section of the filter such that the shaft penetrates the penetrating hole (B) in a state which allows movement of the shaft in the longitudinal direction; wherein the elastomer member is fixed in the distal side of the outer tube.

4. 发明公开

EP3075351A4 VASCULAR PROSTHESIS 审中-公开
标题翻译： GEFÄSSPROTHESE
公开(公告)号：EP3075351A4
公开(公告)日：2017-07-12
申请号：EP14865061
申请日：2014-11-26
申请人： TORAY INDUSTRIES
发明人： TSUCHIKURA HIROSHI , YAMADA SATOSHI , KADOWAKI KOJI , KUWABARA ATSUSHI
IPC分类号： A61F2/06 , A61F2/07 , A61L27/00
CPC分类号： A61F2/06 , A61F2/0077 , A61F2/07 , A61F2002/0086 , A61F2210/0076 , A61F2230/0069 , A61F2240/001 , A61L27/507
摘要： Provided is a vascular prosthesis that has various properties required of it and is highly effective in promoting the settlement of adherent vascular endothelial cells. In particular, provided is a vascular prosthesis with tubular woven structure, the prosthesis comprising an inner layer to be in contact with a blood flow, the inner layer being formed of warp and weft yarns and having a cover factor of 1800 or more, each of the warp and weft yarns comprising a microfiber multifilament yarn with a monofilament fineness of 0.50 dtex or less, the multifilament yarn comprising microfiber monofilaments having an average intersecting angle S of the monofilaments of less than 25°.
摘要翻译：本发明提供一种血管修复剂，其具有所需的各种特性，并且对于促进附着的血管内皮细胞的沉降非常有效。特别地，提供了一种具有管状织造结构的人造血管，所述假体包括与血流接触的内层，所述内层由经纱和纬纱形成并且具有1800或更大的覆盖系数，每个所述经纱和纬纱包含具有0.50dtex或更小的单丝细度的微纤维复丝纱线，所述复丝纱线包括具有小于25°的单丝平均交叉角度S的微纤维单丝。

5. 发明公开

EP3214165A4 FIBER STRUCTURE FOR USE AS CELL SCAFFOLD MATERIAL 审中-公开
公开(公告)号：EP3214165A4
公开(公告)日：2018-07-04
申请号：EP15855508
申请日：2015-10-30
申请人： TORAY INDUSTRIES
发明人： KADOWAKI KOJI , KUGA CHISA , FUJITA MASAKI , TANAHASHI KAZUHIRO , YAMADA SATOSHI , KANEKO TAKAYUKI , TSUCHIKURA HIROSHI
IPC分类号： C12M3/00 , A61L17/10 , A61L17/12 , A61L27/00 , D01F6/62 , D03D1/00
CPC分类号： C12N5/0068 , A61L17/105 , A61L17/12 , A61L27/00 , A61L27/18 , A61L27/50 , C12M3/00 , C12N2533/30 , D01F6/62 , D03D1/00 , D03D15/0088
摘要： The present invention aims to provide a fiber structure which can be used as a cell scaffold material showing improvement in both the cellular adhesiveness and the cell growth capacity, which improvement was achieved by controlling the fiber orientation in the multifilament and the average fiber diameter, which are physical properties. The present invention provides a fiber structure which can be used as a cell scaffold material, which fiber structure comprises a multifilament formed by bundling monofilaments having an average fiber diameter of 1 to 15 µm, wherein each of the monofilaments satisfies the condition of the following Formula 1: (Y/X)×100‰¥50 ... Formula 1 [wherein in Formula 1, X represents the number of monofilaments for which the average crossing angle is investigated, and Y represents the number of monofilaments having an average crossing angle of not more than 25° in X].

6. 发明公开

EP3078389A4 ANTITHROMBOTIC MATERIAL 有权
标题翻译：抗血小板药物
公开(公告)号：EP3078389A4
公开(公告)日：2017-08-09
申请号：EP14866413
申请日：2014-11-27
申请人： TORAY INDUSTRIES
发明人： KADOWAKI KOJI , FUJITA MASAKI , SAKAGUCHI YUKA , TANAHASHI KAZUHIRO
IPC分类号： A61L33/10
CPC分类号： A61L33/0041 , A61L33/0076
摘要： The present invention aims to provide an antithrombogenic material which is highly safe with its low hemolytic toxicity, and capable of maintaining high antithrombogenicity for a long period. The present invention provides an antithrombogenic material comprising: a coating material containing a polymer containing, as a constituent monomer, a compound selected from the group consisting of alkyleneimines, vinylamines, allylamines, lysine, protamine, and diallyldimethylammonium chloride, and an anionic compound containing a sulfur atom and having anticoagulant activity; and a base material whose surface is coated with the coating material; wherein the polymer is covalently bound to the base material, and the abundance ratio of nitrogen atoms to the abundance of total atoms as measured by X-ray photoelectron spectroscopy on the surface is 6.0 to 12.0 atomic percent.
摘要翻译：本发明的目的在于提供一种溶血性毒性低，安全性高，能长期维持高抗血栓性的抗血栓形成物质。本发明提供一种抗血栓形成性材料，其包含：包含含有选自由亚烷基亚胺，乙烯基胺，烯丙基胺，赖氨酸，鱼精蛋白和二烯丙基二甲基氯化铵组成的组中的化合物作为构成单体的聚合物的涂布材料和含有硫原子并具有抗凝血活性; 以及其表面涂覆有涂层材料的基材; 其中所述聚合物共价结合于所述基材，并且通过所述表面上的X射线光电子能谱法测量的氮原子与全部原子的丰度的存在比率为6.0至12.0原子百分比。

7. 发明公开

EP3085335A4 ARTIFICIAL BLOOD VESSEL 审中-公开
标题翻译： KÜNSTLICHESBLUTGEFÄSS
公开(公告)号：EP3085335A4
公开(公告)日：2017-07-19
申请号：EP14871178
申请日：2014-12-16
申请人： TORAY INDUSTRIES
发明人： TSUCHIKURA HIROSHI , YAMADA SATOSHI , KUWABARA ATSUSHI , TOKUDA AKIHIRO , TANAHASHI KAZUHIRO , FUJITA MASAKI , KADOWAKI KOJI
IPC分类号： A61F2/06 , A61L27/00
CPC分类号： A61F2/0063 , A61F2/06 , A61F2002/0068 , A61L27/18 , A61L27/507 , D03D3/02 , D03D13/008 , D03D15/00 , D10B2509/06 , C08L67/02

8. 发明公开

EP2985041A4 ANTITHROMBOTIC ARTIFICIAL BLOOD VESSEL 有权
标题翻译：抗生素治疗
公开(公告)号：EP2985041A4
公开(公告)日：2016-10-19
申请号：EP14782317
申请日：2014-04-10
申请人： TORAY INDUSTRIES
发明人： TANAHASHI KAZUHIRO , SAKAGUCHI YUKA , FUJITA MASAKI , KADOWAKI KOJI , TSUCHIKURA HIROSHI , YAMADA SATOSHI
IPC分类号： A61L27/00 , A61F2/06
CPC分类号： A61F2/86 , A61F2210/0076 , A61F2250/0067 , A61L27/18 , A61L27/507 , A61L27/54 , A61L33/0041 , A61L2300/42 , C08L67/02
摘要： The present invention aims to provide an artificial blood vessel which promotes intimal formation after indwelling, and is capable of maintaining antithrombogenicity during the intimal formation, and of maintaining its patency for a long time. The present invention provides an artificial blood vessel which is a tubular fabric comprising, a fiber layer containing an ultrafine fiber(s) and an ultrafine fiber layer in the inside of the fiber layer, the ultrafine fiber layer being composed of an ultrafine fiber(s) having a fiber diameter(s) of 10 nm to 3 µm, wherein an antithrombin agent having a polymer chain other than heparin is covalently bound to the ultrafine fiber via the polymer chain, and the thrombin activity inhibition rate on the fiber surface at 37°C is not less than 60%.
摘要翻译：本发明的目的在于提供一种人造血管，其能够在留置后促进内膜形成，并且能够在内膜形成期间保持抗血栓形成，并且能够长时间保持其通畅。本发明提供一种人造血管，其是管状织物，其包含在纤维层内部含有超细纤维的纤维层和超细纤维层，超细纤维层由超细纤维），其中具有除肝素以外的聚合物链的抗凝血酶试剂通过聚合物链与超细纤维共价结合，并且纤维表面的凝血酶活性抑制率为37 ℃不小于60％。

9. 发明公开

EP3141213A4 ENDOVASCULAR TREATMENT AID 失效
公开(公告)号：EP3141213A4
公开(公告)日：2018-01-10
申请号：EP15789105
申请日：2015-05-08
申请人： TORAY INDUSTRIES , INOUE KANJI
发明人： INOUE KANJI , YAGI TAKAHIRO , FUJITA MASAKI , KADOWAKI KOJI , TANAHASHI KAZUHIRO
IPC分类号： A61F2/01
CPC分类号： A61F2/013 , A61F2/01 , A61F2002/011 , A61F2002/016 , A61F2230/0067 , A61F2250/0098
摘要： An endovascular treatment aiding device with which adhesion of the endovascular treatment aiding device to a blood vessel can be confirmed, and which can prevent leakage of a captured substance, is disclosed. The endovascular treatment aiding device is an endovascular treatment aiding device comprising: a flexible shaft; a filter fixed to the shaft such that an opening section is formed in the proximal side, wherein a ring having elastic restoring force is fixed to the opening section, which filter is capable of being opened and closed in an umbrella-like manner, and is in a conical shape having a bottom formed by the ring when the filter is open; and a linear supporting member fixed to the ring and a part of the shaft such that these are connected to each other, which linear supporting member enables to close the filter by application of an external force to the proximal side; wherein coils formed with a radio-opaque material is/are wound around the ring; when the filter is closed, a plurality of mountains pointing toward the distal side and a plurality of valleys pointing toward the proximal side are alternately formed in the ring to form a shape in which the mountains are positioned close to each other, and the valleys are positioned close to each other; and the coils are arranged on the ring such that the coils contain the positions fixed by the supporting member on the ring, but do/does not contain the positions of the peaks of the mountains and the peaks of the valleys.

10. 发明公开

EP3106128A4 ARTIFICIAL BLOOD VESSEL 有权
公开(公告)号：EP3106128A4
公开(公告)日：2017-10-18
申请号：EP15749638
申请日：2015-02-12
申请人： TORAY INDUSTRIES
发明人： FUJITA MASAKI , KADOWAKI KOJI , SAKAGUCHI YUKA , TANAHASHI KAZUHIRO , TSUCHIKURA HIROSHI , YAMADA SATOSHI
IPC分类号： A61F2/06 , A61L27/00 , A61L27/18 , A61L27/50 , A61L33/06 , D03D15/00
CPC分类号： A61F2/06 , A61F2210/0076 , A61F2230/0069 , A61L27/18 , A61L27/507 , A61L33/0076 , A61L33/068 , A61L2300/42 , D03D3/02 , D03D15/0061 , D10B2509/06
摘要： The present invention aims to provide an artificial blood vessel composed of a cylindrical multiple-woven fabric structure, which allows only a small amount of blood leakage and can achieve both antithrombogenicity and cellular affinity. The present invention provides an artificial blood vessel comprising a cylindrical fabric structure in which a cylindrical fabric whose inside contacts blood is arranged, wherein the cylindrical fabric is a fabric prepared by interlacing a plurality of warp yarns and a plurality of weft yarns with each other into a cylindrical shape; the warp yarns and the weft yarns constituting the cylindrical fabric comprise a multifilament yarn having a single yarn fineness of not more than 0.50 dtex, and are bound to an antithrombogenic material; the antithrombogenic material forms an antithrombogenic material layer having a thickness of 1 to 600 nm inside the cylindrical fabric; and the water permeability under conditions where a pressure of 16 kPa is applied to the inner surface is less than 300 mL/cm 2 /min.

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式