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1. 发明公开

EP2678045A4 CONTACT LENS CLEANING SYSTEM WITH MONITOR 审中-公开
标题翻译：带显示器隐形眼镜清洁系统
公开(公告)号：EP2678045A4
公开(公告)日：2015-04-22
申请号：EP12749345
申请日：2012-02-23
申请人： NOVABAY PHARMACEUTICALS INC
发明人： FRANCAVILLA CHARLES , NAJAFI RAMIN , LOW EDDY , SHIAU TIMOTHY , TURTLE ERIC DOUGLAS , O'MAHONY DONOGH JOHN ROGER
IPC分类号： A61L12/08 , B08B3/08 , G01N7/18 , G01N25/44 , G01N27/06
CPC分类号： A61L12/128 , C11D3/0078 , C11D3/3947 , G01N7/18 , G02C13/008 , Y10S134/901

2. 发明授权

EP1896001B1 N-HALOGENATED AMINO ACIDS AND N, N-DIHALOGENATED AMINO ACIDS IN COMBINATION WITH HYPOHALOUS ACIDS 有权
标题翻译： N-卤代氨基酸和N，N-二卤代氨基酸结合次卤
公开(公告)号：EP1896001B1
公开(公告)日：2013-06-19
申请号：EP06733945.7
申请日：2006-01-25
申请人： NovaBay Pharmaceuticals, Inc.
发明人： NAJAFI, Ramin , BASSIRI, Mansour , WANG, Lu , KHOSROVI, Behzad
IPC分类号： A61K31/185 , A61K31/197 , A61K31/198 , A61K33/20 , A61P31/00
CPC分类号： A61K45/06 , A61K31/13 , A61K31/18 , A61K31/185 , A61K31/195 , A61K31/197 , A61K31/198 , A61K31/66 , A61K31/69 , A61K33/00 , A61K33/16 , A61K33/18 , A61K33/20 , C07C309/14 , Y02A50/473 , A61K2300/00
摘要： The present invention relates to active bactericidal, antibacterial, anti-infective, antimicrobial, sporicidal, disinfectant, antifungal and antiviral compounds and compositions and to new uses of these compositions in therapy. This specification also describes methods of use for the new compounds and compositions. The specification further describes methods for preparing these compounds. FIG. 1: A dual chamber apparatus for the preparation of NNDCT on site.

3. 发明公开

EP2341886A1 ANTIMICROBIAL N-CHLORINATED COMPOSITIONS 有权
标题翻译：抗微生物的N-氯化化合物
公开(公告)号：EP2341886A1
公开(公告)日：2011-07-13
申请号：EP09825526.8
申请日：2009-11-06
申请人： NovaBay Pharmaceuticals, Inc.
发明人： JAIN, Rakesh, K. , LOW, Eddy , FRANCAVILLA, Charles , SHIAU, Timothy, P. , NAIR, Satheesh, K.
IPC分类号： A61K8/00
CPC分类号： C07C229/12 , A61K31/14 , C07C229/34 , C07C271/54
摘要： The present application relates to N-chlorinated cationic compounds of Formula I or a salt thereof, and associated compositions and methods of use as antimicrobial agents.

4. 发明公开

EP2312939A1 ANTIMICROBIAL GEL FORMULATIONS 审中-公开
标题翻译：抗菌凝胶配方
公开(公告)号：EP2312939A1
公开(公告)日：2011-04-27
申请号：EP09807262.2
申请日：2009-08-12
申请人： NovaBay Pharmaceuticals, Inc.
发明人： WANG, Lu , NAJAFI, Azar , MEMARZADEH, Bahram , SHARMA, Kuldeepak , HO, Kim, Phuong
IPC分类号： A01K9/00
CPC分类号： A61K8/042 , A01N41/08 , A01N59/00 , A61K8/416 , A61K8/44 , A61K8/466 , A61K8/55 , A61K8/8147 , A61K8/86 , A61K9/0014 , A61K9/06 , A61K31/125 , A61K31/352 , A61K47/22 , A61Q5/02 , A61Q11/00 , A61Q17/005 , A61Q19/10 , A01N25/04 , A01N25/10
摘要： Disclosed herein are formulations comprising an
N -halogenated or
N,N - dihalogenated amine compound dispersed in a water-swellable polymer, wherein the compound is 90% stable for at least 30 days at about 25
0 C. Also disclosed are methods of treating or preventing infections caused by a bacterial, a microbial, a sporal, a fungal or a viral activity using such formulations.

5. 发明公开

EP3062829A1 CONTACT LENS CLEANING SYSTEM WITH INSULATION 审中-公开
标题翻译： KONTAKTLINSENREINIGUNGSSYSTEM MIT ISOLIERUNG
公开(公告)号：EP3062829A1
公开(公告)日：2016-09-07
申请号：EP14858437.8
申请日：2014-10-31
申请人： NovaBay Pharmaceuticals, Inc.
发明人： FRANCAVILLA, Charles , STROMAN, David, W.
IPC分类号： A61L12/00 , G02C13/00
CPC分类号： G02C13/008
摘要： The present invention relates generally to systems and methods for cleaning and disinfecting contact lenses. In various respects, the invention is directed to an insulated system that reduces heat loss from catalyzed neutralization of a disinfecting solution resulting in an increased temperature of the disinfection solution during the disinfection process and neutralization of the disinfection solution. The increased temperature increases the kill rate (
i.e., better reduction) of microorganisms present on the lenses, and increases the neutralization rate of the disinfection solution. Increase of the kill rate allows better reduction of microorganisms resistant to elimination using previous systems and methods, (
e.g., Acanthamoeha cysts ), and decreases the amount of time as compared to previous systems and methods necessary to reduce microorganisms to acceptable levels.
摘要翻译：本发明一般涉及用于清洁和消毒隐形眼镜的系统和方法。在各个方面，本发明涉及一种绝缘系统，其减少消毒溶液的催化中和导致的热损失，导致消毒过程中的消毒溶液的温度升高和消毒溶液的中和。增加的温度增加了存在于镜片上的微生物的杀死率（即更好的还原），并且增加了消毒溶液的中和速率。杀死率的提高允许使用先前的系统和方法（例如棘阿米巴孢囊）更好地降低抵抗消除的微生物，并且与以前将微生物降至可接受水平所必需的系统和方法相比，减少了时间量。

6. 发明授权

EP2120965B1 N-HALOGENATED AMINO COMPOUNDS AND DERIVATIVES 有权
标题翻译： N-卤代氨基债券和衍生
公开(公告)号：EP2120965B1
公开(公告)日：2014-11-05
申请号：EP07866112.1
申请日：2007-12-28
申请人： NovaBay Pharmaceuticals, Inc.
发明人： NAJAFI, Ramin , JAIN, Rakesh K. , SHIAU, Timothy P. , LOW, Eddy , NAIR, Satheesh K.
IPC分类号： A61K31/69 , A61K33/14 , C07D211/52 , C07D307/22 , C07C309/05 , C07C309/10 , C07C309/14 , C07C309/17 , C07C309/23 , C07C309/26 , C07C311/32 , A61P31/04
CPC分类号： A61K31/69 , A61K33/00 , C07C309/10 , C07C309/12 , C07C309/17 , C07C309/19 , C07C309/24 , C07C309/26 , C07C311/32 , C07C311/46 , C07C317/28 , C07C2601/14 , C07C2601/18 , C07D211/52 , C07D307/22 , A61K2300/00

7. 发明公开

EP2531026A4 POLYSACCHARIDE BASED ANTIMICROBIAL FORMULATIONS 审中-公开
标题翻译：基于多糖的抗微生物调配
公开(公告)号：EP2531026A4
公开(公告)日：2013-09-25
申请号：EP11740315
申请日：2011-02-02
申请人： NOVABAY PHARMACEUTICALS INC
发明人： NAJAFI AZAR , MEMARZADEH BAHRAM , IBRAHIM SARAH A , ANDERSON MARK BRIAN
IPC分类号： A01N41/06 , A61K31/145 , A61K47/36
CPC分类号： A61K31/185 , A01N41/08 , A01N59/00 , A61K8/416 , A61K8/46 , A61K8/466 , A61K8/49 , A61K8/4926 , A61K8/4946 , A61K8/55 , A61K9/0048 , A61K31/14 , A61K31/145 , A61K31/4166 , A61K31/421 , A61K31/4425 , A61K31/66 , A61K47/36 , A61K2800/74 , A61L2/16 , A61L2202/24 , A61Q19/00 , A01N25/04 , A01N2300/00

8. 发明公开

EP2312939A4 ANTIMICROBIAL GEL FORMULATIONS 审中-公开
标题翻译：抗菌凝胶配方
公开(公告)号：EP2312939A4
公开(公告)日：2012-10-31
申请号：EP09807262
申请日：2009-08-12
申请人： NOVABAY PHARMACEUTICALS INC
发明人： WANG LU , NAJAFI AZAR , MEMARZADEH BAHRAM , SHARMA KULDEEPAK , HO KIM PHUONG
IPC分类号： A01K9/00
CPC分类号： A61K8/042 , A01N41/08 , A01N59/00 , A61K8/416 , A61K8/44 , A61K8/466 , A61K8/55 , A61K8/8147 , A61K8/86 , A61K9/0014 , A61K9/06 , A61K31/125 , A61K31/352 , A61K47/22 , A61Q5/02 , A61Q11/00 , A61Q17/005 , A61Q19/10 , A01N25/04 , A01N25/10

9. 发明公开

EP2120965A4 N-HALOGENATED AMINO COMPOUNDS AND DERIVATIVES 有权
标题翻译： N-HALOGENIERTE AMINOVERBINDUNGEN UND DERIVATE
公开(公告)号：EP2120965A4
公开(公告)日：2011-05-18
申请号：EP07866112
申请日：2007-12-28
申请人： NOVABAY PHARMACEUTICALS INC
发明人： NAJAFI RAMIN , JAIN RAKESH K , SHIAU TIMOTHY P , LOW EDDY , NAIR SATHEESH K
IPC分类号： A61K31/69 , A61K33/14 , A61P31/04 , C07C309/05 , C07C309/10 , C07C309/14 , C07C309/17 , C07C309/23 , C07C309/26 , C07C311/32 , C07D211/52 , C07D307/22
CPC分类号： A61K31/69 , A61K33/00 , C07C309/10 , C07C309/12 , C07C309/17 , C07C309/19 , C07C309/24 , C07C309/26 , C07C311/32 , C07C311/46 , C07C317/28 , C07C2601/14 , C07C2601/18 , C07D211/52 , C07D307/22 , A61K2300/00

10. 发明公开

EP2678045A2 CONTACT LENS CLEANING SYSTEM WITH MONITOR 审中-公开
标题翻译：带显示器隐形眼镜清洁系统
公开(公告)号：EP2678045A2
公开(公告)日：2014-01-01
申请号：EP12749345.0
申请日：2012-02-23
申请人： NovaBay Pharmaceuticals, Inc.
发明人： FRANCAVILLA, Charles , NAJAFI, Ramin , LOW, Eddy , SHIAU, Timothy , TURTLE, Eric Douglas , O'MAHONY, Donogh John Roger
IPC分类号： A61L12/08 , B08B3/08
CPC分类号： A61L12/128 , C11D3/0078 , C11D3/3947 , G01N7/18 , G02C13/008 , Y10S134/901
摘要： The invention monitors the neutralization process involving hydrogen peroxide solution and a hydrogen peroxide neutralization catalyst and compares measured values with theoretical values. The system monitors the chemical reaction and notifies the user of the neutralization status. In an exemplary embodiment, the initial hydrogen peroxide solution concentration is neutralized with a palladium catalyst after a period of time. A microcontroller analyzes the measurements and displays the neutralization process results using colored LED lights and/or text or images on a LCD display. In one embodiment, an apparatus adapted for use with a cleaning solution used to clean a medical device may include a trigger, a processing device in communication with the trigger, and a display device. The processing device provides a trigger count and the display device communicates with the processing device and displays a message based on the count.

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