专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

EP3296290B1 CYCLIC PROCESS FOR PRODUCING TAURINE 有权
公开(公告)号：EP3296290B1
公开(公告)日：2018-11-14
申请号：EP17187912.5
申请日：2017-08-25
申请人： Vitaworks IP, LLC
发明人： Hu, Songzhou
IPC分类号： C07C303/02 , C07C303/32 , C07C303/44 , C07C303/22 , C07C309/14 , C07C309/08
CPC分类号： C07C303/02 , C07C303/22 , C07C303/32 , C07C303/44 , C07C309/14 , C07C309/08
摘要： There is disclosed a process for producing taurine from ammonium isethionate by the ammonolysis of alkali isethionate in the presence of alkali ditaurinate or alkali tritaurinate, or their mixture, to inhibit the formation of byproducts and to continuously convert the byproducts of the ammonolysis reaction to alkali taurinate. Alkali taurinate is reacted with ammonium isethionate to obtain taurine and to regenerate alkali isethionate. The production yield is increased to from 90% to nearly quantitative. The ammonolysis reaction is catalyzed by alkali salts of hydroxide, sulfate, sulfite, phosphate, or carbonate.

2. 发明公开

EP3351529A1 PROCESS FOR PRODUCING ALKALI TAURINATE 审中-公开
公开(公告)号：EP3351529A1
公开(公告)日：2018-07-25
申请号：EP18154790.2
申请日：2015-04-03
申请人： Vitaworks IP, LLC
发明人： HU, Songzhou
IPC分类号： C07C309/14 , C07C303/02 , C07C303/32 , C07C303/44
CPC分类号： C07C303/32 , C07C303/02 , C07C303/44 , C07C309/14
摘要： There is disclosed a process for producing alkali taurinate from alkali isethionate by the ammonolysis of a solution of alkali isethionate, alkali ditaurinate, and alkali tritaurinate, or a solution of alkali ditaurinate and alkali tritaurinate. The overall yield of alkali taurinate from alkali isethionate is obtained to from 90% to nearly quantitative. The ammonolysis reaction is catalyzed by alkali salts of hydroxide, sulfate, sulfite, or carbonate.

3. 发明公开

EP3287439A1 METHOD FOR PREPARING TAURINE 审中-公开
标题翻译：牛磺酸的制备方法
公开(公告)号：EP3287439A1
公开(公告)日：2018-02-28
申请号：EP16820142.4
申请日：2016-07-01
申请人： QIANJIANG YONGAN PHARMACEUTICAL CO., LTD
发明人： CHEN, Yong , FANG, Xiquan , LI, Shaobo , JIANG, Xiaojun
IPC分类号： C07C303/02 , C07C309/14
CPC分类号： C07C303/44 , C07C303/22 , C07C303/32 , C07C309/08 , C07C309/14
摘要： The present application provides a process for producing taurine, comprising the steps as follows: (a) mixing isethionic acid with taurine salt solution until the system pH reaches a certain value in a range from 5.0 to 9.5; (b) separating liquid phase and solid phase of the system; wherein said solid phase is the crude product of taurine, and said liquid phase is isethionate solution; (c) reacting ammonia solution with said liquid phase obtained from step (b) to obtain taurine salt solution. It uses isethionic acid to adjust the pH of the taurine salt solution, avoiding the problem causing by using sulphate acid to adjust the pH in the traditional process. By the recycling use of the cations in taurine salts, a new raw material or reagent does not need to be added which is benefit to reducing the use of dangerous chemical materials, simplifying the production process greatly, improving the utilization rate of raw materials, increasing the yield of the product and decreasing production cost significantly.
摘要翻译：本发明提供了一种牛磺酸的生产方法，包括如下步骤：（a）将羟乙基磺酸与牛磺酸盐溶液混合，直至体系pH值达到5.0-9.5的一定值; （b）分离系统的液相和固相; 其中所述固相是牛磺酸的粗产物，并且所述液相是羟乙磺酸盐溶液; （c）使氨溶液与从步骤（b）获得的所述液相反应以获得牛磺酸盐溶液。它使用羟乙磺酸调节牛磺酸盐溶液的pH值，避免了在传统工艺中使用硫酸酸调节pH值造成的问题。通过牛磺酸盐中阳离子的循环使用，不需要添加新的原料或试剂，有利于减少危险化学物质的使用，大大简化了生产工艺，提高了原料的利用率，提高了产品的产量和生产成本显着降低。

4. 发明公开

EP3279186A1 PROCESS FOR PRODUCING TAURINE 审中-公开
标题翻译：生产牛磺酸的方法
公开(公告)号：EP3279186A1
公开(公告)日：2018-02-07
申请号：EP17157022.9
申请日：2017-02-20
申请人： Vitaworks IP, LLC
发明人： HU, Songzhou
IPC分类号： C07C303/22 , C07C303/44
CPC分类号： C07C303/22 , C07C303/44 , C07C309/14
摘要： There is disclosed a process for producing taurine by the ammonolysis of alkali isethionate in the presence of alkali ditaurinate or alkali tritaurinate, or their mixture, to inhibit the formation of byproducts and to continuously convert the byproducts of the ammonolysis reaction to alkali taurinate. The production yield is increased to from 90% to nearly quantitative. The ammonolysis reaction is catalyzed by alkali salts of hydroxide, sulfate, sulfite, phosphate, or carbonate.
摘要翻译：本发明公开了一种在碱金属二月桂酸盐或三碲酸碱金属盐或它们的混合物的存在下通过碱金属羟乙基磺酸盐的氨解生产牛磺酸以抑制副产物形成并连续将氨解反应的副产物转化为碱金属牛磺酸盐的方法。产量从90％增加到接近定量。氨解反应由氢氧化物，硫酸盐，亚硫酸盐，磷酸盐或碳酸盐的碱金属盐催化。

5. 发明公开

EP3235808A1 MODIFIED TAURINE, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING METABOLIC DISEASES CONTAINING SAME 审中-公开
标题翻译：改性牛磺酸和用于预防或治疗含有相同代谢疾病的药物组合物
公开(公告)号：EP3235808A1
公开(公告)日：2017-10-25
申请号：EP15870313.2
申请日：2015-12-16
申请人： Byun, Jonghyun
发明人： Byun, Jonghyun
IPC分类号： C07C309/14 , A61K31/18 , A61K31/7004 , A61P3/04 , A61P3/10
CPC分类号： A61K31/18 , A61K9/00 , A61K9/0019 , A61K9/08 , A61K31/145 , A61K31/185 , A61K31/195 , A61K31/70 , A61K31/7004 , A61K47/183 , A61K47/20 , A61K47/26 , C07B2200/13 , C07C309/14 , A61K2300/00
摘要： The present invention relates to a modified taurine, and a pharmaceutical composition for preventing or treating metabolic disease or a food composition, which contains the modified taurine as an active ingredient. More specifically, the modified taurine of the present invention has physical properties different from those of existing taurine, and has significant effects on the prevention and treatment of metabolic syndrome, including antithrombotic effects.
摘要翻译：本发明涉及改性牛磺酸和用于预防或治疗代谢疾病的药物组合物或含有改性牛磺酸作为活性成分的食品组合物。更具体地说，本发明的改性牛磺酸具有与现有牛磺酸不同的物理性质，并且对包括抗血栓形成作用在内的代谢综合症的预防和治疗具有显着效果。

6. 发明公开

EP3210970A1 PROCESS FOR PRODUCING TAURINE FROM ALKALI TAURINATES 审中-公开
标题翻译：从碱金属牛磺酸盐生产牛磺酸的方法
公开(公告)号：EP3210970A1
公开(公告)日：2017-08-30
申请号：EP17157026.0
申请日：2017-02-20
申请人： Vitaworks IP, LLC
发明人： HU, Songzhou
IPC分类号： C07C303/44 , C07C303/22 , C07C309/14
CPC分类号： C07C303/22 , B01J27/02 , B01J27/053 , B01J27/055 , B01J27/08 , B01J27/10 , B01J27/1806 , B01J27/232 , B01J27/25 , B01J31/04 , B01J2231/005 , B01J2531/002 , C07C303/44 , C07C309/14
摘要： The present invention discloses a process and catalysts for producing taurine by catalytic ammonolysis of alkali ditaurinate, alkali tritaurinate, and their mixture. Useful catalysts are the ammonium and alkali salts of sulfate, bisulfate, sulfite, bisulfite, carbonate, bicarbonate, nitrate, phosphate, and organic carboxylic acids.
摘要翻译：本发明公开了一种牛磺酸碱金属盐，三萜酸碱金属盐及其混合物的催化氨解生产牛磺酸的方法及催化剂。有用的催化剂是硫酸盐，硫酸氢盐，亚硫酸盐，亚硫酸氢盐，碳酸盐，碳酸氢盐，硝酸盐，磷酸盐和有机羧酸的铵盐和碱盐。

7. 发明公开

EP3207027A1 NOVEL IMAGING COMPOSITION AND USES THEREOF 有权
标题翻译：新的成像组合物及其用途
公开(公告)号：EP3207027A1
公开(公告)日：2017-08-23
申请号：EP15850792.1
申请日：2015-10-16
申请人： The University of Melbourne
发明人： DONNELLY, Paul Stephen , RUDD, Stacey Erin , WILLIAMS, Spencer John
IPC分类号： C07C235/80 , C07C247/14 , C07C261/02 , C07K17/06 , A61K51/10 , A61K103/20 , A61K103/30 , A61K103/00
CPC分类号： A61K31/18 , A61K51/1051 , C07C259/06 , C07C309/14 , C07C311/19 , C07C311/29 , C07C311/42 , C07C311/46 , C07C323/60 , C07C2601/04 , C07D207/48 , C07D211/60 , C07D211/96 , C07D213/42 , C07D213/74 , C07D213/89 , C07D215/36 , C07D223/06 , C07D277/06 , C07D277/80 , C07D279/12 , C07D295/13 , C07D309/06 , C07D401/12 , C07D405/12 , C07D413/12 , C07D453/06 , C07D471/08 , C07D487/08
摘要： The invention discussed in this application relates to hydroxamic acid-based compounds that are useful as imaging agents when bound to an appropriate metal centre, particularly for the imaging of tumours.
摘要翻译：本申请中讨论的本发明涉及基于异羟肟酸的化合物，其当与适当的金属中心结合时用作成像剂，特别是用于肿瘤成像。

8. 发明授权

EP2912012B1 VERFAHREN ZUR HERSTELLUNG VON ZWITTERIONISCHEN MONOMEREN SOWIE DIE VERWENDUNG DIESER MONOMERE 有权
标题翻译：用于生产两性离子单体和本单体的使用
公开(公告)号：EP2912012B1
公开(公告)日：2016-12-14
申请号：EP13791748.0
申请日：2013-10-23
申请人： Karlsruher Institut Für Technologie (KIT)
发明人： KRATZER, Domenic , FRIEDMANN, Christian , LAHANN, Jörg
IPC分类号： C07C303/32 , C07C309/14
CPC分类号： C08F120/38 , C07C303/32 , C07C309/14

9. 发明授权

EP2813854B1 HEMOLYSIS REAGENT COMPOSITION FOR HEMOGLOBIN A1C QUANTITATIVE ANALYSIS USING ENZYMATIC METHOD 有权
标题翻译： HÄMOLYSEREAGENZZUSAMMENSETZUNG血红蛋白A1C的定量分析手段酶促过程的
公开(公告)号：EP2813854B1
公开(公告)日：2016-09-07
申请号：EP12867965.1
申请日：2012-11-16
申请人： i-Sens, Inc.
发明人： SHEN, Dongxuan , CHO, Joo Young , PARK, Kap Soo , CHA, Geun Sig , NAM, Hakhyun
IPC分类号： G01N33/72 , C07C211/63 , C12Q1/37
CPC分类号： G01N33/5091 , C07C309/14 , C12Q1/26 , G01N33/721 , G01N2333/805

10. 发明公开

EP2978404A1 TAURINE COMPOSITIONS SUITABLE FOR INHALATION 审中-公开
标题翻译：适合吸入的牛磺酸组合物
公开(公告)号：EP2978404A1
公开(公告)日：2016-02-03
申请号：EP14712756.7
申请日：2014-03-26
申请人： Vectura Limited
发明人： FARROW, David , COGGINS, Katie
IPC分类号： A61K9/00 , A61K47/20 , A61K9/16 , A61K31/137 , A61K31/40 , A61K31/4045 , C07C309/14 , A61P11/00
CPC分类号： A61K9/1617 , A61K9/0075 , A61K9/008 , A61K9/1682 , A61K31/137 , A61K31/138 , A61K31/167 , A61K31/185 , A61K31/40 , A61K31/439 , A61K31/4704 , A61K31/58 , A61K45/06 , C07C303/42 , C07C309/14 , A61K2300/00
摘要： The invention discloses spray-dried compositions for inhalation and methods for preparing such powder compositions. The compositions of the invention are produced by spray-drying taurine under conditions that (i) retain the physical and chemical stability of the composition during spray drying and upon storage, (ii) protect the powder composition from aggregation and (iii) provide particles suitable for aerosolisation.
摘要翻译：本发明公开了用于吸入的喷雾干燥组合物和制备这种粉末组合物的方法。（i）在喷雾干燥和储存期间保持组合物的物理和化学稳定性，（ii）保护粉末组合物免于聚集，和（iii）提供适合于本发明组合物的颗粒用于雾化。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式