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11. 发明授权

EP2744125B1 SIGNAL TRANSMITTING METHOD, SIGNAL RECEIVING METHOD, PASSIVE OPTICAL NETWORK DEVICE AND SYSTEM 有权
标题翻译： SIGNALÜBERTRAGUNGSVERFAHREN，SIGNALEMPFANGSVERFAHREN，被动OPTISCHE NETZWERKVORRICHTUNG系统DAFÜR
公开(公告)号：EP2744125B1
公开(公告)日：2017-06-21
申请号：EP11864796.5
申请日：2011-09-15
申请人： Huawei Technologies Co., Ltd. , The Hong Kong Polytechnic University
发明人： ZHOU, Lei , WEI, Guo , LV, Chao , WANG, Dawei , LIU, Botao
IPC分类号： H04B10/00 , H04B10/2587 , H04B10/63 , H04B10/61 , H04B10/27 , H04B10/532 , H04J14/02
CPC分类号： H04B10/27 , H04B10/532 , H04B10/614 , H04B10/6151 , H04J14/02

12. 发明授权

EP2188259B1 QUINOLINE DERIVATIVES AS ANTI-CANCER AGENTS 有权
标题翻译： ALS CHINOLINDERIVATE ANTIKREBSMITTEL
公开(公告)号：EP2188259B1
公开(公告)日：2013-11-06
申请号：EP08784083.1
申请日：2008-08-21
申请人： The Hong Kong Polytechnic University
发明人： CHAN, Albert Sun-chi , TANG, Johnny Cheuk-on , LAM, Kim-hung , CHUI, Chung-hin , KOK, Stanton Hon-lung , CHAN, Sau Hing , CHEUNG, Filly , FERRARA, Roberto Gambari , CHENG, Chor Hing
IPC分类号： C07D215/26 , A61K31/438 , A61P35/00
CPC分类号： C07D215/06 , A61K31/438 , A61K31/47 , A61K31/4709 , C07D215/14 , C07D215/18 , C07D215/20 , C07D215/26

13. 发明公开

EP2436358A1 RECOVERING SYSTEM FOR TRAINING USER TO MOVE HANDS 有权
标题翻译： GENESUNGSSYSTEM ZUM手工制作EINES BENUTZERS
公开(公告)号：EP2436358A1
公开(公告)日：2012-04-04
申请号：EP10780074.0
申请日：2010-05-26
申请人： The Hong Kong Polytechnic University
发明人： TONG, Kai Yu , HO, Sie Kit , CHAN, Tai Wai David , CHEN, Mo , ZHOU, Hongfu , PANG, Man Kit Peter
IPC分类号： A61H1/02 , A63B23/16
CPC分类号： B25J9/0006 , A61H1/0285 , A61H1/0288 , A61H2201/0157 , A61H2201/0192 , A61H2201/123 , A61H2201/1261 , A61H2201/1638 , A61H2201/165 , A61H2201/1676 , A61H2201/5007 , A61H2201/5025 , A61H2201/5061 , A61H2201/5064 , A61H2230/605 , A63B21/00181 , A63B21/4019 , A63B21/4021 , A63B21/4035 , A63B21/4047 , A63B23/14 , A63B23/16 , A63B24/0006 , A63B71/0622 , A63B2071/0627 , A63B2071/0647 , A63B2220/10 , A63B2220/51 , A63B2230/605
摘要： A recovering system (10) for training a user to move hands includes a platform (24) connected to the hands and multiple finger components (71) operatively connected to the platform (24). Each finger component (71) includes a motor (12), a proximal follow-up component (13) which is applied to a metacarpophalangeal joint and includes a proximal guide rail (14) operatively connected to the motor (12), and a middle follow-up component (16) which is applied to a near knuckle and includes a middle guide rail (17) operatively connected to the proximal follow-up component (13). The knuckle indicator (22) of the proximal guide rail (14) corresponds to the first virtual center (30). The knuckle indicator (25) of the middle guide rail (17) corresponds to the second virtual center (31). The knuckles (22, 25) are aligned to the virtual centers (30, 31) so that when the proximal follow-up component (13) and the middle follow-up component (16) are activated by the motor (12), the movement of the fingers can be controlled, and the rotation axis of the fingers can be kept being around each virtual center (30, 31).
摘要翻译：用于训练用户移动手的恢复系统（10）包括连接到手的平台（24）和可操作地连接到平台（24）的多个手指部件（71）。每个指状部件（71）包括马达（12），近端随动部件（13），其被施加到掌指关节并且包括可操作地连接到马达（12）的近侧导轨（14）跟随部件（16），其被施加到近关节并且包括可操作地连接到近侧跟随部件（13）的中间导轨（17）。近侧导轨（14）的关节指示器（22）对应于第一虚拟中心（30）。中间导轨（17）的转向节指示器（25）对应于第二虚拟中心（31）。指关节（22,25）与虚拟中心（30,31）对准，使得当近侧跟踪部件（13）和中间随动部件（16）被马达（12）激活时，可以控制手指的移动，并且可以将手指的旋转轴保持在每个虚拟中心（30,31）周围。

14. 发明公开

EP2411040A1 Site-directed pegylation of arginases and the use thereof as anti-cancer and anti-viral agents 有权
标题翻译：精氨酸酶的定点聚乙二醇化及其作为抗癌剂和抗病毒剂的用途
公开(公告)号：EP2411040A1
公开(公告)日：2012-02-01
申请号：EP10769236.0
申请日：2010-03-26
申请人： The Hong Kong Polytechnic University
发明人： LEUNG, Thomas, Yun-Chung , LO, Thomas, Wai-Hung
IPC分类号： A61K38/43 , A61P35/00 , A61P31/00
CPC分类号： C12N9/78 , A61K38/00 , A61K47/60 , C12Y305/03001
摘要： Mono-pegylated arginase conjugate and method producing thereof. The mono-pegylated arginase is homogeneous in molecular weight and shows therapeutic effect for treating cancers and viral infections. The method of producing such arginase conjugate has a main step of genetically modifying the gene encoding an arginase so that the PEG moiety can attach to the enzyme at a predetermined, specific intended site. This is achieved by removing the PEG attaching amino acid residues at undesirable sites while keeping (or adding, if necessary) the one at the desirable site of the enzyme. Two exemplary mono-pegylated arginase conjugates so produced are human arginase I (HAI) where a polyethylene glycol (PEG) moiety is site-specific covalently bonded to Cys
45 of the enzyme and
Bacillus caldovelox arginase (BCA) where a polyethylene glycol (PEG) moiety is site-specific covalently bonded to Cys
161 of the enzyme.
摘要翻译：单聚乙二醇化精氨酸酶缀合物及其生产方法。单聚乙二醇化精氨酸酶在分子量上是均匀的，并显示出治疗癌症和病毒感染的治疗效果。生产这种精氨酸酶缀合物的方法具有对编码精氨酸酶的基因进行遗传修饰的主要步骤，使得PEG部分可以在预定的特定预定位点附着于酶。这是通过除去不希望的位点上的PEG连接氨基酸残基，同时保持（或者如果需要，添加）在期望的酶位点处的氨基酸残基。如此产生的两种示例性单聚乙二醇化精氨酸酶缀合物是其中聚乙二醇（PEG）部分是位点特异性共价结合至酶和Caldovelox精氨酸酶（BCA）的Cys45的人精氨酸酶I（HAI），其中聚乙二醇（PEG）部分是位点特异性共价键合到酶的Cys161。

15. 发明公开

EP2321327A1 ZWITTERIONIC PHOSPHONIUM SALTS 审中-公开
标题翻译：两性离子鏻
公开(公告)号：EP2321327A1
公开(公告)日：2011-05-18
申请号：EP09802322.9
申请日：2009-07-29
申请人： The Royal Institution for the Advancement of Learning / McGill University , The Hong Kong Polytechnic University
发明人： CHAN, Tak-Hang , HUO, Congde , HE, Xun
IPC分类号： C07F9/54 , C07C1/207 , C07C41/56
CPC分类号： C07F9/5325 , C07C1/324 , C07C41/30 , C07C41/56 , C07F9/5022 , C07F9/5442 , C07F9/5456 , C07C11/02 , C07C43/215 , C07C43/313 , C07C43/307 , C07C43/315
摘要： A zwitterionic phosphonium salt of Formula I: wherein n is 0 or 1; R is H or SO
3
- ; R' is selected from the group consisting of C
1 -C
10 alkyl, C
2 -C
10 alkenyl, C
2 -C
10 alkynyl, C
3 -C
10 cycloalkyl, phenyl, substituted phenyl, benzyl and C
1 -C
10 alkoxycarbonyl; R' is CX
3 when n is O; and X is selected from the group consisting of F, Cl, Br and I. The zwitterionic phosphonium salts are useful reagents for the preparation of alkenes and acetals from the corresponding aldehyde.

16. 发明公开

EP2261001A1 VERTICAL MICROINJECTION MACHINE 有权
标题翻译： VERTIKALMIKROINJEKTIONSMASCHINE
公开(公告)号：EP2261001A1
公开(公告)日：2010-12-15
申请号：EP09716266.3
申请日：2009-03-03
申请人： The Hong Kong Polytechnic University
发明人： YUNG, Kai-leung
IPC分类号： B29C45/64 , B29C45/03 , B29C45/74 , B29C45/77 , B29C45/76
CPC分类号： B29C45/66 , B29C45/1761 , B29C45/53 , B29C45/76 , B29C2045/0094 , B29C2945/76006 , B29C2945/76013 , B29C2945/762 , B29C2945/7621 , B29C2945/76381
摘要： A vertical microinjection machine comprises a base (1) and a driving unit, a plasticizing unit, an injection unit, a mould closing system which are arranged on the base (1), wherein the mould closing system comprises a lower mould plate (2) which is fixed on the base (1) by a bracket arranged on the base (1), an upper mould plate (3) which is movable upward and downward relative to the lower mould plate (2), and two independent mould closing drive units which are symmetrically arranged on the base. Each mould closing drive unit comprises two thrust rods (5), a transmission part, a screw rod, a servo motor (4), a square "□" shaped support frame and a linear guide. The servo motor (4) drives the screw rod, and then brings the transmission part to move up and down. Driven by the transmission mechanism, the thrust rods (5) open and close the upper and lower clamping plates (3, 2) so as to achieve the opening and closing operation.
摘要翻译：一种垂直显微注射机，包括一个设置在基座（1）上的基座（1）和一个驱动单元，一个塑化单元，一个注射单元，一个闭合系统，其中该闭模系统包括下模板（2）其通过布置在基座（1）上的支架固定在基座（1）上，相对于下模板（2）上下移动的上模板（3）和两个独立的闭模驱动单元它们对称地布置在基座上。每个闭模驱动单元包括两个推杆（5），传动部分，螺杆，伺服马达（4），正方形“形支撑框架和直线导轨。伺服电机（4）驱动螺杆，然后使传动部件上下移动。由传动机构驱动，推杆（5）打开和关闭上下夹板（3,2），以实现打开和关闭操作。

17. 发明公开

EP2028703A3 Fabrication of piezoelectric single crystalline thin layer on silicon wafer 审中-公开
标题翻译：在硅晶片上制造压电单晶薄膜
公开(公告)号：EP2028703A3
公开(公告)日：2010-09-01
申请号：EP08162225.0
申请日：2008-08-12
申请人： The Hong Kong Polytechnic University
发明人： Peng, Jue , Chao, Chen , Dai, Jiyan , Chan, Helen L.W.
IPC分类号： H01L41/22 , B81C1/00 , B06B1/06
CPC分类号： H01L41/1875 , H01L41/29 , H01L41/312 , H01L41/332 , H01L41/337
摘要： The present invention relates a method of fabricating a piezoelectric device through micromachining piezoelectric-on-silicon wafer. The wafers are constructed so that piezoelectric layer is a single wafer having a thin layer from 5 to 50 µm.

18. 发明公开

EP2142244A1 MEDICAL DEVICE FOR DELIVERING DRUG AND/OR PERFORMING PHYSICAL THERAPY 审中-公开
标题翻译：医疗设备使其在药物和/或到物理疗法的实施
公开(公告)号：EP2142244A1
公开(公告)日：2010-01-13
申请号：EP08734166.5
申请日：2008-04-25
申请人： The Hong Kong Polytechnic University
发明人： LEUNG, Woon-Fong, Wallace , LO, Chun-Lap, Samuel
IPC分类号： A61M37/00 , A61M5/172 , A61B5/00 , A61H23/00
CPC分类号： A61B5/4839 , A61B5/01 , A61B5/14539 , A61B5/4266 , A61B5/441 , A61B5/4878 , G06F19/00
摘要： Current methods of delivering drug usually require a certain degree of human intervention. For example, a doctor, a paramedic or a patient is required to inject insulin manually when the blood sugar level becomes low. This invention provides a medical device for use with a patient for performing at least one of the functions of delivering drug and performing physical therapy to the patient. The device of this invention includes a sensor for measuring at least one parameter from the patient, an analyzer for analyzing the parameter to determine appropriate function to be carried out on the patient by said medical device, and at least one actuator to perform at least one of the functions of delivering drug and performing physical therapy.

19. 发明公开

EP2028703A2 Fabrication of piezoelectric single crystalline thin layer on silicon wafer 审中-公开
标题翻译：在硅晶片上制造压电单晶薄膜
公开(公告)号：EP2028703A2
公开(公告)日：2009-02-25
申请号：EP08162225.0
申请日：2008-08-12
申请人： The Hong Kong Polytechnic University
发明人： Peng, Jue , Chao, Chen , Dai, Jiyan , Chan, Helen L.W.
IPC分类号： H01L41/22 , B81C1/00
CPC分类号： H01L41/1875 , H01L41/29 , H01L41/312 , H01L41/332 , H01L41/337
摘要： The present invention relates a method of fabricating a piezoelectric device through micromachining piezoelectric-on-silicon wafer. The wafers are constructed so that piezoelectric layer is a single wafer having a thin layer from 5 to 50 µm.
摘要翻译：本发明涉及微加工通过压电上的硅晶片制造压电器件的方法。晶片被构造成没有压电体层是具有从5至50微米的薄的层的单晶片。

20. 发明公开

EP1582430A1 System and process for monitoring railway tracks 审中-公开
标题翻译：系统和方法监控铁路
公开(公告)号：EP1582430A1
公开(公告)日：2005-10-05
申请号：EP04251840.7
申请日：2004-03-29
申请人： The Hong Kong Polytechnic University
发明人： Tam, Hwayaw The Hong Kong Polytechnic University , Ho, Siu Lau The Hong Kong Polytechnic University , Liu, Michael Shun Yee
IPC分类号： B61L23/04 , B61L1/16
CPC分类号： B61L1/166 , B61L23/041
摘要： A railway monitoring system firstly includes an optical fiber. A first part of the fiber is attachable to one of a pair of tracks of a rail, and a characteristic of the first part of the fiber is variable in correspondence to variance of a characteristic of said one track where the first part of fiber is attached. The system also includes an optical signal emitter connected to the fiber for emitting an optical signal into the fiber, and the fiber generates at least a first altered optical signal, which contains information relating to the variance of the characteristic of the part of the fiber. The system further includes an optical signal analyzer connected to the fiber for receiving and analyzing the first altered optical signal so as to ascertain the variance of said characteristic of said one track based upon the information contained in the first altered optical signal.

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