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1. 发明专利

CZ5190U1 Antimicrobial therapeutic composition 未知
公开(公告)号：CZ5190U1
公开(公告)日：1996-11-13
申请号：CZ556296
申请日：1996-07-15
申请人： SUROVEC JAN , JALOVCIAR VLADIMIR ING , VUTCH CHEMITEX
发明人： SUROVEC JAN ING , JALOVCIAR VLADIMIR ING , SLAVIK JURAJ ING , KABATOVA VIERA ING
IPC分类号： A61K33/38 , A61K47/02 , A61K033/38 , A61K047/02

2. 发明申请

US20040213760A1 Composition and method for delivery of biologically-active factors 失效
标题翻译：用于递送生物活性因子的组合物和方法
公开(公告)号：US20040213760A1
公开(公告)日：2004-10-28
申请号：US10672144
申请日：2003-09-26
发明人： Lawrence Tamarkin , Giulio F. Paciotti
IPC分类号： A61K038/16 , A61K038/19 , A61K038/20 , A61K033/38 , A61K038/21
CPC分类号： A61K39/39 , A61K2039/55505 , A61K2039/55516 , A61K2039/55522 , C07K16/241 , C07K2317/77
摘要： In accordance with the present invention, a composition and method is provided that allows for the administration of a biologically-active factors to a human or animal. The present invention can be used to treat a disease with a biologically-active factor or combination of biologically-active factors, or can be used to safely vaccinate a human or animal against a biologically-active factor. It can also be used as a method for the delivery of biologically-active factors for the treatment of disease. Additionally, the present invention also includes a method of targeted drug delivery for the treatment of disease through the administration of custom complexes containing of one or more biologically active factors bound to a colloidal metal where at least one of the biologically-active factors is capable of binding a high affinity receptor on a cell surface.
摘要翻译：根据本发明，提供了允许向人或动物施用生物活性因子的组合物和方法。本发明可用于治疗具有生物活性因子或生物活性因子组合的疾病，或可用于安全地针对生物活性因子对人或动物进行疫苗接种。它也可以用作递送用于治疗疾病的生物活性因子的方法。此外，本发明还包括通过施用含有结合到胶体金属的一种或多种生物活性因子的定制复合物来治疗疾病的靶向药物递送的方法，其中至少一种生物活性因子能够在细胞表面上结合高亲和力受体。

3. 发明申请

US20040180098A1 Anti-microbial powder coatings 审中-公开
标题翻译：抗微生物粉末涂料
公开(公告)号：US20040180098A1
公开(公告)日：2004-09-16
申请号：US10807726
申请日：2004-03-24
发明人： Owen H. Decker , Michael A. Sparks , Jeffrey R. Hagerlin , Frederick L. Cummings , Peter Gottschling
IPC分类号： A61K033/42 , A61K033/38
CPC分类号： C09D5/14 , A01N25/10 , A01N25/34 , A01N35/02 , A01N37/34 , A01N37/40 , A01N41/10 , A01N43/80 , A01N47/04 , C09D5/033 , A01N2300/00
摘要： Improved powder coatings exhibit enhanced resistance to bacterial and fungal attack, while possessing excellent toughness, appearance, corrosion resistance, durability, processability, and ease of application. The coating is comprised of anti-microbial agents that are homogeneously dispersed within the powder or impact fused to powder particles or both. An article may be coated with a thermoset thermoplastic, or radiation curable powder, which may be applied by electrostatic spray or fluidized bed or by thermal or flame spray.
摘要翻译：改进的粉末涂料具有增强的对细菌和真菌侵袭的抗性，同时具有优异的韧性，外观，耐腐蚀性，耐久性，可加工性和易于使用。涂层由抗微生物剂组成，其均匀分散在粉末中或与粉末颗粒或两者融合。制品可以用热固性热塑性塑料或可辐射固化粉末涂覆，其可以通过静电喷雾或流化床或通过热或火焰喷涂施用。

4. 发明申请

US20040126433A1 Light stabilized antimicrobial materials 有权
标题翻译：光稳定的抗菌材料
公开(公告)号：US20040126433A1
公开(公告)日：2004-07-01
申请号：US10734784
申请日：2003-12-12
发明人： David Parsons , Elizabeth Jacques , Philip Bowler
IPC分类号： A61K033/38 , A61L015/00
CPC分类号： A61L31/16 , A61K31/28 , A61K31/74 , A61K33/38 , A61L15/44 , A61L26/0066 , A61L27/54 , A61L29/16 , A61L2300/102 , A61L2300/104 , A61L2300/404 , A61L2300/45 , A61K2300/00
摘要： Methods of enhancing the photostabilizing of silver in medical materials are described. More particularly, the methods increase the photostabilization of silver in certain materials comprising hydrophilic, amphoteric and anionic polymers by subjecting the polymers to solutions containing an organic solvent and silver, during or after which one or more agents are added which facilitate the photostablization of the material.
摘要翻译：描述了增强医疗材料中银的光稳定性的方法。更具体地说，这种方法通过使聚合物经受有机溶剂和银的溶液使某些包含亲水性，两性和阴离子聚合物的材料的光稳定化增加，在此期间或之后，加入一种或多种促进材料光稳定化的试剂。

5. 发明申请

US20040101572A1 Microbial control system 审中-公开
标题翻译：微生物控制系统
公开(公告)号：US20040101572A1
公开(公告)日：2004-05-27
申请号：US10383168
申请日：2003-03-05
发明人： Bryan E. Kepner , Sherman M. Ponder
IPC分类号： A61K033/24 , A61K033/38 , A61K033/34
CPC分类号： C02F1/505 , A01N59/16 , A01N59/20 , C02F2201/006 , A01N25/10 , A01N25/12 , A01N2300/00
摘要： Te invention relates to a microbial control system for treating influent water and sump water for control of microbial material in machines which process water such as ice making machines, humidifiers such as cool mist humidifiers and cooling towers. The microbial control system includes antimicrobial treatment media housed in a containment vessel. The treatment media can include any one or more of transition metals and transition metal oxides. The transition metal may be any of Sc, Ti, V, Cr, Mn, Fe, Co, Ni, Cu, Zn, Y, Zr, Nb, Mo, Tc, Ru, Rh, Pd, Ag, Cd, Hf, Ta, W, Re, Os, Ir, Pt, Au, Hg, Rf, Db, Sg, Bh, Hs, Mt, Uun, Uuu and Uub.
摘要翻译：本发明涉及一种微生物控制系统，用于处理流入水和水槽，用于控制加工水的机器中的微生物物质，如制冰机，加湿器如冷雾加湿器和冷却塔。微生物控制系统包括容纳在容纳容器中的抗微生物处理介质。处理介质可以包括任何一种或多种过渡金属和过渡金属氧化物。过渡金属可以是Sc，Ti，V，Cr，Mn，Fe，Co，Ni，Cu，Zn，Y，Zr，Nb，Mo，Tc，Ru，Rh，Pd，Ag，Cd，Hf，Ta ，W，Re，Os，Ir，Pt，Au，Hg，Rf，Db，Sg，Bh，Hs，Mt，Uun，Uuu和Uub。

6. 发明申请

US20040081706A1 Alginate containing antimicrobial composition 审中-公开
标题翻译：含有海藻酸盐的抗微生物组合物
公开(公告)号：US20040081706A1
公开(公告)日：2004-04-29
申请号：US10425411
申请日：2003-04-29
发明人： Eilidh Trainer , Thomas Gilchrist
IPC分类号： A61K033/38 , A61K033/06 , A61K031/729
CPC分类号： A61L26/0095 , A61L26/0023 , C08L5/04
摘要： There is provided a composition comprising an admixture of a finely divided alginate (or a salt or derivative thereof) together with a finely divided carrier material. The composition overcomes the problems associated with applying gel-forming alginates to a body surface without formation of a clumpy paste that leads to local irritation. An admixture of sodium alginate and a water-soluble glass carrier material is preferred. Optionally, the alginate and carrier material each have a particle size of less than 150 nullm diameter and are present in a weight ration of 20:30 to 80:20. The presence of the carrier aids even gel formation and also promotes wound healing.
摘要翻译：提供了一种组合物，其包含细分散的藻酸盐（或其盐或衍生物）与细分散的载体材料的混合物。该组合物克服了将凝胶形成藻酸盐施用于身体表面而不形成导致局部刺激的团块状糊剂的问题。优选藻酸钠和水溶性玻璃载体材料的混合物。任选地，藻酸盐和载体材料各自具有小于150μm直径的粒度，并且以20:30至80:20的重量比进行存在。载体的存在有助于甚至形成凝胶并且还促进伤口愈合。

7. 发明申请

US20040043048A1 Cosmetic containing anti-bacterial agent and process for production thereof 审中-公开
标题翻译：含有抗菌剂的化妆品及其生产方法
公开(公告)号：US20040043048A1
公开(公告)日：2004-03-04
申请号：US10653897
申请日：2003-09-04
申请人： Ishizuka Garasu Kabushiki Kaisha , SHIN-EI CHEMICAL CO., LTD. , Cosmo Trends Corporation
发明人： Makio Nomura , Reiko Nojima , Togo Murata
IPC分类号： A61K033/38 , A61K007/00
CPC分类号： A61Q1/12 , A61K8/0241 , A61K8/19 , A61K8/25 , A61K33/38 , A61K45/06 , A61K2800/651 , Y02A50/473
摘要： Disclosed herein are (1) cosmetic made with silver type anti-microbial water soluble glass in oily cosmetic composition of the cosmetic, and (2) a process for producing the cosmetic that is highly effective against bacteria and fungi, and that is safer to the skin. The cosmetic is characterized by letting silver type anti-microbial water soluble glass in oily cosmetic composition release slowly from oil phase of the cosmetic to the water phase of the cosmetic only when anti-bacterial agent contact with water in the cosmetic.
摘要翻译：本文公开了（1）化妆品的油性化妆品组合物中用银型抗微生物水溶性玻璃制成的化妆品，和（2）对细菌和真菌高度有效的化妆品的制备方法，并且对于皮肤。化妆品的特征在于，当化妆品中的抗菌剂与水接触时，将油性化妆品组合物中的银型抗微生物水溶性玻璃缓慢地从化妆品的油相释放到化妆品的水相。

8. 发明申请

US20040009964A1 Compositions and methods for the treatment of matrix metalloproteinase-related diseases 审中-公开
标题翻译：用于治疗基质金属蛋白酶相关疾病的组合物和方法
公开(公告)号：US20040009964A1
公开(公告)日：2004-01-15
申请号：US10391054
申请日：2003-03-18
申请人： BioInterface Technologies, Inc.
发明人： Christopher J. Capelli
IPC分类号： A61K031/555 , A61K031/28 , A61K033/38
CPC分类号： A61K33/38
摘要： The present invention relates to the use of water-soluble photo-stable silver thiosulfate ion complexes that are antimicrobially active and inhibit the activity of metalloproteinases. The present invention describes incorporation of these complexes into medical devices and/or wound dressings to prevent or treat symptomology related to microbial infections and/or conditions of excessive tissue destruction. In particular, these complexes may be useful in the treatment of rheumatoid arthritis and/or osteoarthritis in the prevention and treatment of articular bone joint degradation and subsequent reductions in joint swelling and pain.
摘要翻译：本发明涉及抗微生物活性并抑制金属蛋白酶活性的水溶性光稳定性硫代硫酸银离子络合物的用途。本发明描述了将这些复合物掺入到医疗装置和/或伤口敷料中以预防或治疗与微生物感染和/或过度组织破坏的条件相关的症状。特别地，这些复合物可用于治疗类风湿性关节炎和/或骨关节炎，以预防和治疗关节骨关节退化，随后减少关节肿胀和疼痛。

9. 发明申请

US20040009227A1 Thermoplastic particles which comprise an antiviral or antimicrobial agent 审中-公开
标题翻译：包含抗病毒剂或抗微生物剂的热塑性颗粒
公开(公告)号：US20040009227A1
公开(公告)日：2004-01-15
申请号：US10408095
申请日：2003-04-08
申请人： Porex Corporation
发明人： Li Yao
IPC分类号： A61K033/38 , A61K009/14 , A61K031/17 , A61K031/075 , A61K031/155
CPC分类号： A61L9/042 , A01N25/10 , A01N25/34 , A01N31/16 , A61L2/23 , A01N2300/00
摘要： This invention relates to novel porous materials that possess antiviral and/or antimicrobial properties. The invention encompasses a porous material having antiviral or antimicrobial properties-which is comprised of a porous substrate and an antiviral or antimicrobial agent. The invention also encompasses a process for making porous materials that possess antiviral and/or antimicrobial properties and the products of the process.
摘要翻译：本发明涉及具有抗病毒和/或抗微生物特性的新型多孔材料。本发明包括具有抗病毒或抗微生物性质的多孔材料，其由多孔底物和抗病毒或抗微生物剂组成。本发明还包括一种制备具有抗病毒和/或抗微生物特性的多孔材料和该方法的产物的方法。

10. 发明申请

US20040005364A1 Antimicrobial and immunostimulating composition 审中-公开
标题翻译：抗微生物和免疫刺激组合物
公开(公告)号：US20040005364A1
公开(公告)日：2004-01-08
申请号：US10460760
申请日：2003-06-12
发明人： Barbara K. Klein , Leo D. Katzner
IPC分类号： A61K033/38 , A61K031/715
CPC分类号： A61K31/716 , A61K33/38 , A61L15/44 , A61L15/46 , A61L31/16 , A61L2300/104 , A61L2300/232 , A61L2300/404 , A61L2300/426 , A61L2300/45 , Y02A50/473
摘要： A medical composition comprising an antimicrobially effective and immunostimulating amount of a combination of a null-glucan component and a silver-containing component is disclosed. The medical composition may be adapted for use topically or incorporated with a mesh material which may be further adapted for use as a wound dressing or as a surgical mesh. Methods for manufacturing the medical compositions described herein are also provided. The invention further provides methods for treating tissue damaged by wound or burn, and methods for treating or repairing tissue at a surgical site.
摘要翻译：公开了包含抗微生物和免疫刺激量的β-葡聚糖组分和含银组分的组合的药物组合物。该医疗组合物可以适用于局部使用或与网状材料结合，所述网状材料可以进一步适合用作伤口敷料或外科手术网。还提供了用于制造本文所述医药组合物的方法。本发明还提供了用于治疗由伤口或烧伤损伤的组织的方法，以及在手术部位处理或修复组织的方法。

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