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1. 发明申请

US20100160889A1 VIAL ACCESS SPIKE ASSEMBLY 审中-公开
标题翻译： VIAL ACCESS SPIKE总成
公开(公告)号：US20100160889A1
公开(公告)日：2010-06-24
申请号：US12341473
申请日：2008-12-22
申请人： Donald A. Smith , Steven C. Jepson , Thomas E. Dudar
发明人： Donald A. Smith , Steven C. Jepson , Thomas E. Dudar
IPC分类号： A61J1/14
CPC分类号： A61J1/2096 , A61J1/201 , A61J1/2055
摘要： A spike assembly having an elongate spike defining a hollow cannula that is in fluid communication with the interior of a luer connection portion. The spike assembly provides needleless access to a stopper of a vial to facilitate injection and withdrawal of fluids via a syringe barrel selectively secured to the luer connection portion. The syringe can safely be removed from the spike assembly and then be directly attached to a luer compatible connector. The elongate spike may include a frangible tip portion that can break away from the spike assembly within a vial. The spike assembly may have a neck with a pair of gripping wing members. The spike assembly may have a feature that prevents rotation of the spike in the vial stopper, thereby allowing the syringe to be easily and safely disconnected from the spike assembly without having to grasp the spike assembly.
摘要翻译：尖钉组件，其具有限定中空插管的细长尖端，其与鲁尔连接部分的内部流体连通。尖钉组件提供对瓶的塞子的无针入口，以便于通过选择性地固定到鲁尔连接部分的注射器筒的注射和抽出流体。注射器可以安全地从尖钉组件移除，然后直接连接到鲁尔兼容连接器。细长的尖钉可以包括易碎的尖端部分，其可以在小瓶内脱离尖钉组件。尖钉组件可以具有带有一对夹持翼构件的颈部。尖钉组件可以具有防止瓶塞中的尖头旋转的特征，从而允许注射器容易且安全地从尖钉组件断开，而不必抓住尖钉组件。

2. 发明授权

US06669681B2 Needleless connector 有权
公开(公告)号：US06669681B2
公开(公告)日：2003-12-30
申请号：US09903134
申请日：2001-07-11
申请人： Steven C. Jepson , Thomas E. Dudar , Rodrigo A. Montanez , Algirdas J. Bindokas , Michael J. Finley , Jason J. White , Camille Summers
发明人： Steven C. Jepson , Thomas E. Dudar , Rodrigo A. Montanez , Algirdas J. Bindokas , Michael J. Finley , Jason J. White , Camille Summers
IPC分类号： A61M500
CPC分类号： A61M39/045 , A61M2039/0036 , Y10S128/912
摘要： A needless connector is provided which utilizes a resealable preslit septum valve. The valve is resiliently restrained relative to a housing with the valve and housing configured to accept a standard male luer lock having a luer tip which penetrates the valve through the opening to extend within the housing and a luer locking flange of the luer lock extending about the housing. The valve includes a disk shaped upper portion covering the opening, a lower portion spaced from the housing and extending downward from the disk shaped portion into a passageway defined by the housing, and an annular skirt to attach the septum to the housing. The connector exhibits satisfactory leak pressure after multiple connections and disconnects to the luer lock fitting and long periods of indwell of the luer tip.

3. 发明授权

US06569125B2 Pre-slit injection site and tapered cannula 失效
标题翻译：预切口注射部位和锥形插管
公开(公告)号：US06569125B2
公开(公告)日：2003-05-27
申请号：US09907234
申请日：2001-07-17
申请人： Steven C. Jepson , Thomas E. Dudar , Michael J. Finley , Vincent C. Desecki
发明人： Steven C. Jepson , Thomas E. Dudar , Michael J. Finley , Vincent C. Desecki
IPC分类号： A61M528
CPC分类号： A61J1/2089 , A61J1/10 , A61J1/1406 , A61J1/1475 , A61J1/201 , A61J1/2055 , A61J1/2096 , A61M5/162 , A61M39/045 , A61M39/1011 , A61M39/14 , A61M2039/1033 , A61M2039/1066 , A61M2039/1072 , A61M2205/195 , A61M2205/197 , Y10S604/905
摘要： A pre-slit injection site (34) includes a housing (40) with a flow path therethrough. A first end (42) of the housing (40) carries a pre-slit septum (52). One form of a blunt cannula (98), usable with the injection site (34), carries a locking member (100). When the pre-slit injection site (34) slidably receives the blunt cannula (98), the locking member (100) latches to the injection site (34) and creates a mechanically coupled unit. Another form of the cannula (280) includes a tube having a tapered distal end region (298) and having elongate discharge slots (294) for reducing contact surface area and for directing the flow laterally out of the cannula. The cannula may also include a rounded lead post (330), an annular barb (394), and axially oriented grooves (268).
摘要翻译：预狭缝注射部位（34）包括具有穿过其中的流动通道的壳体（40）。壳体（40）的第一端（42）承载预切口隔膜（52）。可与注射部位（34）一起使用的钝性插管（98）的一种形式承载锁定构件（100）。当预狭缝注射部位（34）可滑动地接收钝头套管（98）时，锁定构件（100）锁定到注射部位（34）并产生机械耦合单元。套管（280）的另一种形式包括具有锥形远端区域（298）并且具有细长的排出槽（294）的管子，用于减少接触表面积并将流体横向导引出套管。插管还可以包括圆形引导柱（330），环形倒钩（394）和轴向定向的凹槽（268）。

4. 发明授权

US5957898A Needleless connector 失效
公开(公告)号：US5957898A
公开(公告)日：1999-09-28
申请号：US81728
申请日：1998-05-20
申请人： Steven C. Jepson , Thomas E. Dudar , Rodrigo A. Montanez , Algirdas J. Bindokas , Michael J. Finley , Jason J. White , Camille Summer , Samuel Ding , Lewis E. Daniels
发明人： Steven C. Jepson , Thomas E. Dudar , Rodrigo A. Montanez , Algirdas J. Bindokas , Michael J. Finley , Jason J. White , Camille Summer , Samuel Ding , Lewis E. Daniels
IPC分类号： A61M39/02 , A61M5/14 , A61M39/04 , A61M5/00
CPC分类号： A61M39/045 , A61M2005/1404 , A61M2039/0036 , A61M2039/263 , Y10S128/912
摘要： A needless connector is provided which utilizes a resealable preslit septum valve. The valve is resiliently restrained relative to a housing with the valve and housing configured to accept a standard male luer lock having a luer tip which penetrates the valve through the opening to extend within the housing and a luer locking flange of the luer lock extending about the housing. The valve includes a disk shaped upper portion covering the opening, a lower portion spaced from the housing and extending downward from the disk shaped portion into a passageway defined by the housing, and an annular skirt to attach the septum to the housing. The connector exhibits satisfactory leak pressure after multiple connections and disconnects to the luer lock fitting and long periods of indwell of the luer tip.

5. 发明授权

US5411499A Needleless vial access device 失效
标题翻译：无针管进样装置
公开(公告)号：US5411499A
公开(公告)日：1995-05-02
申请号：US737735
申请日：1991-07-30
申请人： Thomas E. Dudar , Peter L. Graham , Steven C. Jepson
发明人： Thomas E. Dudar , Peter L. Graham , Steven C. Jepson
IPC分类号： A61J3/00 , A61J1/00 , A61J1/14 , A61J1/20 , A61M5/162 , A61M5/32 , A61M5/34 , A61M39/04 , A61M39/14 , A61M37/00
CPC分类号： A61J1/2089 , A61J1/2096 , A61M39/045 , A61M39/14 , A61M5/162 , A61J1/1406 , A61J1/201 , A61J2200/10 , A61M2005/3201 , A61M2039/1072 , A61M2205/195 , A61M2205/197
摘要： A cannula assembly adapted to pierce a solid or unslit closure is disclosed and includes a blunt cannula and a piercing member held in cooperation with or contained within the flow channel of the cannula. Generally, the piercing member includes a tip capable of piercing an unslit stopper or closure and a means to temporarily retain the piercing member from the cannula and prevent inadvertent disengagement of the piercing member from the blunt cannula.
摘要翻译：公开了一种适于穿透固体或未照明的封闭物的插管组件，其包括与套管的流动通道配合或包含在套管的流动通道内的钝性插管和刺穿构件。通常，刺穿构件包括能够刺穿未点燃的止动器或闭合件的尖端以及临时将穿刺构件从套管保持的装置，并且防止刺穿构件与钝头插管无意中脱离接触。

6. 发明授权

US06605076B1 Pre-slit injection site and tapered cannula 失效
公开(公告)号：US06605076B1
公开(公告)日：2003-08-12
申请号：US08699083
申请日：1996-08-09
申请人： Steven C. Jepson , Thomas E. Dudar , Brian D. Zdeb , Vince C. Desecki
发明人： Steven C. Jepson , Thomas E. Dudar , Brian D. Zdeb , Vince C. Desecki
IPC分类号： A61M2516
CPC分类号： A61M39/1011 , A61J1/10 , A61J1/1406 , A61J1/1475 , A61J1/201 , A61J1/2037 , A61J1/2044 , A61J1/2055 , A61J1/2089 , A61J1/2096 , A61J2200/10 , A61M5/162 , A61M39/045 , A61M39/14 , A61M2039/1033 , A61M2039/1072 , A61M2039/1077 , A61M2205/195 , A61M2205/197
摘要： A pre-slit injection site includes a housing with a flow path therethrough. A first end of the housing carries a pre-slit septum. One form of a blunt cannula, usable with the injection site, carries a locking member. When the pre-slit injection site slidably receives the blunt cannula, the locking member latches to the injection site and creates a mechanically coupled unit. Another form of the cannula includes a tube having a tapered distal end region and having elongate discharge slots for reducing contact surface area and for directing the flow laterally out of the cannula. The cannula may also include a rounded lead post, an annular barb, and axially oriented grooves.

7. 发明授权

US06447498B1 Pre-slit injection site and tapered cannula 失效
标题翻译：预切口注射部位和锥形插管
公开(公告)号：US06447498B1
公开(公告)日：2002-09-10
申请号：US09182571
申请日：1998-10-29
申请人： Steven C. Jepson , Thomas E. Dudar , Brian D. Zdeb , Vince C. Desecki
发明人： Steven C. Jepson , Thomas E. Dudar , Brian D. Zdeb , Vince C. Desecki
IPC分类号： A61M532
CPC分类号： A61M39/1011 , A61J1/10 , A61J1/1406 , A61J1/1475 , A61J1/201 , A61J1/2037 , A61J1/2044 , A61J1/2055 , A61J1/2089 , A61J1/2096 , A61J2200/10 , A61M5/162 , A61M39/045 , A61M39/14 , A61M2039/1033 , A61M2039/1072 , A61M2039/1077 , A61M2205/195 , A61M2205/197
摘要： A pre-slit injection site includes a housing with a flow path therethrough. A first end of the housing carries a pre-slit septum. One form of a blunt cannula, usable with the injection site, carries a locking member. When the pre-slit injection site slidably receives the blunt cannula, the locking member latches to the injection site and creates a mechanically coupled unit. Another form of the cannula includes a tube having a tapered distal end region and having elongate discharge slots for reducing contact surface area and for directing the flow laterally out of the cannula. The cannula may also include a rounded lead post, an annular barb, and axially oriented grooves.
摘要翻译：预狭缝注射部位包括具有穿过其中的流动通道的壳体。外壳的第一端装有预狭缝隔膜。与注射部位一起使用的钝性插管的一种形式携带锁定构件。当预狭缝注射部位可滑动地接收钝头套管时，锁定构件锁定到注射部位并产生机械耦合单元。套管的另一种形式包括具有锥形远端区域并且具有用于减少接触表面积并用于将流体横向导出套管的细长排出槽的管。套管还可以包括圆形引导柱，环形倒钩和轴向定向的凹槽。

8. 发明授权

US5776125A Needleless vial access device 失效
标题翻译：无针管进样装置
公开(公告)号：US5776125A
公开(公告)日：1998-07-07
申请号：US427063
申请日：1995-04-24
申请人： Thomas E. Dudar , Peter L. Graham , Steven C. Jepson
发明人： Thomas E. Dudar , Peter L. Graham , Steven C. Jepson
IPC分类号： A61J3/00 , A61J1/00 , A61J1/14 , A61J1/20 , A61M5/162 , A61M5/32 , A61M5/34 , A61M39/04 , A61M39/14 , A61M37/00
CPC分类号： A61J1/2089 , A61J1/2096 , A61M39/045 , A61M39/14 , A61M5/162 , A61J1/1406 , A61J1/201 , A61J2200/10 , A61M2005/3201 , A61M2039/1072 , A61M2205/195 , A61M2205/197
摘要： The present invention provides a piercing member adapted for use with a flow channel. The piercing member has a penetrating member for piercing a solid closure, and is retained to the flow channel, but still allows fluid to flow through the flow channel while retained to the flow channel.
摘要翻译：本发明提供一种适于与流动通道一起使用的穿孔构件。刺穿构件具有用于刺穿固体闭合件的穿透构件，并且保持在流动通道中，但是仍然允许流体在保持流动通道的同时流过流动通道。

9. 发明授权

US06213996B1 Pre-slit injection site and tapered cannula 失效
公开(公告)号：US06213996B1
公开(公告)日：2001-04-10
申请号：US09182260
申请日：1998-10-29
申请人： Steven C. Jepson , Thomas E. Dudar , Michael J. Finley , Vincent C. Desecki
发明人： Steven C. Jepson , Thomas E. Dudar , Michael J. Finley , Vincent C. Desecki
IPC分类号： A61M2500
CPC分类号： A61J1/2089 , A61J1/10 , A61J1/1406 , A61J1/1475 , A61J1/201 , A61J1/2055 , A61J1/2096 , A61M5/162 , A61M39/045 , A61M39/1011 , A61M39/14 , A61M2039/1033 , A61M2039/1066 , A61M2039/1072 , A61M2205/195 , A61M2205/197 , Y10S604/905
摘要： A pre-slit injection site (34) includes a housing (40) with a flow path therethrough. A first end (42) of the housing (40) carries a pre-slit septum (52). One form of a blunt cannula (98), usable with the injection site (34), carries a locking member (100). When the pre-slit injection site (34) slidably receives the blunt cannula (98), the locking member (100) latches to the injection site (34) and creates a mechanically coupled unit. Another form of the cannula (280) includes a tube having a tapered distal end region (298) and having elongate discharge slots (294) for reducing contact surface area and for directing the flow laterally out of the cannula. The cannula may also include a rounded lead post (330), an annular barb (394), and axially oriented grooves (268).

10. 发明授权

US5433330A Needleless access stopper 失效
标题翻译：无针门禁
公开(公告)号：US5433330A
公开(公告)日：1995-07-18
申请号：US312004
申请日：1994-09-23
申请人： Thomas Yatsko , Jerome D. Olivas , Edward F. Vander Bush , William A. Conard , Steven C. Jepson , Thomas E. Dudar
发明人： Thomas Yatsko , Jerome D. Olivas , Edward F. Vander Bush , William A. Conard , Steven C. Jepson , Thomas E. Dudar
IPC分类号： B65D51/18 , A61J1/00 , A61J1/05 , A61J1/14 , A61J1/20 , B65D51/00 , B65D51/22 , B65D39/00 , B65D41/20
CPC分类号： B65D51/222 , A61J1/1406 , A61J1/2096 , B65D51/002 , A61J1/201 , B65D2251/0015 , B65D2251/0056 , B65D2251/009 , Y10S215/03
摘要： Disclosed is a stopper for use with containers to provide needleless access to the container with a cannula having a blunt penetrating tip. Also disclosed is a system comprising the stopper, container and cannula. The stopper includes a disc having an upper face and a lower face, and a plug extending from the disc into the container. Also included is a diaphragm, defined by a target region in the upper face and a cross channel in the disc for controlling the force needed to penetrate the stopper with the cannula. The plug includes a first inward surface for guiding the cannula and a second inward surface for engaging the cannula to minimize wetting of the outside of the cannula. In a preferred embodiment, the first surface extends down from the cross channel on the lower side of the disc, radially outwardly to a maximum diameter and the second inwardly facing surface extends down from the first surface radially inwardly to a minimum diameter to form the cannula seal. Also shown is a centrally located piercing point positioned to pre-slit the diaphragm. An overcap may be provided to alternatively have an axially aligned boss and bore positioned to pre-slit the diaphragm. In another embodiment, the invention includes an annular pre-slit disc formed of self sealing material and positioned to reduce spray back when inserting or removing the cannula.
摘要翻译：公开了一种用于与容器一起使用具有钝的穿透尖端的套管来无菌地进入容器的塞子。还公开了一种包括塞子，容器和套管的系统。止动器包括具有上表面和下表面的盘，以及从盘延伸到容器中的塞子。还包括由上表面中的目标区域和盘中的横向通道限定的隔膜，用于控制用套管穿透塞子所需的力。塞子包括用于引导套管的第一向内表面和用于接合套管的第二向内表面以最小化插管外部的润湿。在优选实施例中，第一表面从盘的下侧的交叉通道向下延伸，径向向外延伸到最大直径，并且第二向内表面从第一表面径向向内延伸至最小直径以形成插管密封。还示出了定位成预先切割隔膜的位于中心的穿刺点。可以提供顶盖以备选地具有轴向对齐的凸台和孔，以便预先切割隔膜。在另一个实施例中，本发明包括由自密封材料形成并定位成在插入或移除插管时减少喷雾的环形预切割盘。

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