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1. 发明授权

US5871500A Pre-slit injection site and tapered cannula 失效
公开(公告)号：US5871500A
公开(公告)日：1999-02-16
申请号：US583457
申请日：1996-01-05
申请人： Steven C. Jepson , Thomas E. Dudar , Brian D. Zdeb , Vince C. Desecki
发明人： Steven C. Jepson , Thomas E. Dudar , Brian D. Zdeb , Vince C. Desecki
IPC分类号： A61M39/02 , A61J1/00 , A61J1/05 , A61J1/10 , A61J1/14 , A61J1/20 , A61M5/00 , A61M5/162 , A61M25/00 , A61M25/02 , A61M37/00 , A61M39/00 , A61M39/04 , A61M39/14 , A61M29/00
CPC分类号： A61M39/1011 , A61J1/2089 , A61J1/2096 , A61M39/045 , A61M39/14 , A61M5/162 , A61J1/10 , A61J1/1406 , A61J1/1475 , A61J1/201 , A61J1/2037 , A61J1/2044 , A61J1/2055 , A61J2200/10 , A61M2039/1033 , A61M2039/1072 , A61M2039/1077 , A61M2205/195 , A61M2205/197
摘要： A pre-slit injection site includes a housing with a flow path therethrough. A first end of the housing carries a pre-slit septum. One form of a blunt cannula, usable with the injection site, carries a locking member. When the pre-slit injection site slidably receives the blunt cannula, the locking member latches to the injection site and creates a mechanically coupled unit. Another form of the cannula includes a tube having a tapered distal end region and having elongate discharge slots for reducing contact surface area and for directing the flow laterally out of the cannula. The cannula may also include a rounded lead post, an annular barb, and axially oriented grooves.

2. 发明授权

US06605076B1 Pre-slit injection site and tapered cannula 失效
公开(公告)号：US06605076B1
公开(公告)日：2003-08-12
申请号：US08699083
申请日：1996-08-09
申请人： Steven C. Jepson , Thomas E. Dudar , Brian D. Zdeb , Vince C. Desecki
发明人： Steven C. Jepson , Thomas E. Dudar , Brian D. Zdeb , Vince C. Desecki
IPC分类号： A61M2516
CPC分类号： A61M39/1011 , A61J1/10 , A61J1/1406 , A61J1/1475 , A61J1/201 , A61J1/2037 , A61J1/2044 , A61J1/2055 , A61J1/2089 , A61J1/2096 , A61J2200/10 , A61M5/162 , A61M39/045 , A61M39/14 , A61M2039/1033 , A61M2039/1072 , A61M2039/1077 , A61M2205/195 , A61M2205/197
摘要： A pre-slit injection site includes a housing with a flow path therethrough. A first end of the housing carries a pre-slit septum. One form of a blunt cannula, usable with the injection site, carries a locking member. When the pre-slit injection site slidably receives the blunt cannula, the locking member latches to the injection site and creates a mechanically coupled unit. Another form of the cannula includes a tube having a tapered distal end region and having elongate discharge slots for reducing contact surface area and for directing the flow laterally out of the cannula. The cannula may also include a rounded lead post, an annular barb, and axially oriented grooves.

3. 发明授权

US06447498B1 Pre-slit injection site and tapered cannula 失效
标题翻译：预切口注射部位和锥形插管
公开(公告)号：US06447498B1
公开(公告)日：2002-09-10
申请号：US09182571
申请日：1998-10-29
申请人： Steven C. Jepson , Thomas E. Dudar , Brian D. Zdeb , Vince C. Desecki
发明人： Steven C. Jepson , Thomas E. Dudar , Brian D. Zdeb , Vince C. Desecki
IPC分类号： A61M532
CPC分类号： A61M39/1011 , A61J1/10 , A61J1/1406 , A61J1/1475 , A61J1/201 , A61J1/2037 , A61J1/2044 , A61J1/2055 , A61J1/2089 , A61J1/2096 , A61J2200/10 , A61M5/162 , A61M39/045 , A61M39/14 , A61M2039/1033 , A61M2039/1072 , A61M2039/1077 , A61M2205/195 , A61M2205/197
摘要： A pre-slit injection site includes a housing with a flow path therethrough. A first end of the housing carries a pre-slit septum. One form of a blunt cannula, usable with the injection site, carries a locking member. When the pre-slit injection site slidably receives the blunt cannula, the locking member latches to the injection site and creates a mechanically coupled unit. Another form of the cannula includes a tube having a tapered distal end region and having elongate discharge slots for reducing contact surface area and for directing the flow laterally out of the cannula. The cannula may also include a rounded lead post, an annular barb, and axially oriented grooves.
摘要翻译：预狭缝注射部位包括具有穿过其中的流动通道的壳体。外壳的第一端装有预狭缝隔膜。与注射部位一起使用的钝性插管的一种形式携带锁定构件。当预狭缝注射部位可滑动地接收钝头套管时，锁定构件锁定到注射部位并产生机械耦合单元。套管的另一种形式包括具有锥形远端区域并且具有用于减少接触表面积并用于将流体横向导出套管的细长排出槽的管。套管还可以包括圆形引导柱，环形倒钩和轴向定向的凹槽。

4. 发明授权

US5797897A Pre-slit injection site and tapered cannula 失效
公开(公告)号：US5797897A
公开(公告)日：1998-08-25
申请号：US470380
申请日：1995-06-06
申请人： Steven C. Jepson , Thomas E. Dudar , Brian D. Zdeb , Vince C. Desecki
发明人： Steven C. Jepson , Thomas E. Dudar , Brian D. Zdeb , Vince C. Desecki
IPC分类号： A61M39/02 , A61J1/00 , A61J1/05 , A61J1/10 , A61J1/14 , A61J1/20 , A61M5/00 , A61M5/162 , A61M25/00 , A61M25/02 , A61M37/00 , A61M39/00 , A61M39/04 , A61M39/14 , A61M29/00
CPC分类号： A61M39/1011 , A61J1/2089 , A61J1/2096 , A61M39/045 , A61M39/14 , A61M5/162 , A61J1/10 , A61J1/1406 , A61J1/1475 , A61J1/201 , A61J1/2037 , A61J1/2044 , A61J1/2055 , A61J2200/10 , A61M2039/1033 , A61M2039/1072 , A61M2039/1077 , A61M2205/195 , A61M2205/197
摘要： A pre-slit injection site includes a housing with a flow path therethrough. A first end of the housing carries a pre-slit septum. One form of a blunt cannula, usable with the injection site, carries a locking member. When the pre-slit injection site slidably receives the blunt cannula, the locking member latches to the injection site and creates a mechanically coupled unit. Another form of the cannula includes a tube having a tapered distal end region and having elongate discharge slots for reducing contact surface area and for directing the flow laterally out of the cannula. The cannula may also include a rounded lead post, an annular barb, and axially oriented grooves.

5. 发明授权

US4850978A Drug delivery cartridge with protective cover 失效
标题翻译：带防护罩的药物输送筒
公开(公告)号：US4850978A
公开(公告)日：1989-07-25
申请号：US114814
申请日：1987-10-29
申请人： Thomas E. Dudar , Brian D. Zdeb
发明人： Thomas E. Dudar , Brian D. Zdeb
IPC分类号： A61M5/14 , A61M37/00 , A61M39/00
CPC分类号： A61M5/1409
摘要： A cartridge 444, 644, 744 is adapted for mounting upon a receptacle 442, 642 in a parenterial fluid administration set 420 for delivering a drug or other beneficial agent to a patient. The cartridge 444, 644, 744 includes a beneficial agent-containing chamber 606 slidable from a first, pre-use position to a second, post-use position. The cartridge includes a hollow tube 496 in which the chamber 606 is at least partially mounted. At least one cannula 500 is mounted to the hollow tube and extends opposite the chamber. A protective cover or cap 530 maintains a chamber protective position that prevents inadvertent movement of the chamber that would accidentally engage the cartridge chamber with a flow path member, such as the cannula. The cover is removed in order to engage the chamber. After delivery of the agent to the patient, the cartridge is removed from the receptacle 442,642 and the cover 530 is selectively moved to a cannula protective position in which the cover 530 is securely mounted about the second, opposite end of the hollow tube, covering the cannula 500.
摘要翻译：药筒444,644,744适于安装在肠胃外流体给药组420中的容器442,642上，用于将药物或其它有益药物递送给患者。盒444,644,744包括可从第一使用前位置向第二使用后位置滑动的有益剂容纳室606。盒包括中空管496，其中室606至少部分地安装在其中。至少一个插管500安装到中空管并且与腔相对延伸。保护盖或盖530保持室保护位置，防止腔室意外地与诸如插管的流路构件接合盒室的意外移动。盖子被移除以便接合室。在将药剂递送到患者之后，将药筒从容器442,642中取出，并且将盖530选择性地移动到插管保护位置，在套管保护位置中，盖530围绕中空管的第二相对端牢固地安装，套管500。

6. 发明授权

US4804366A Cartridge and adapter for introducing a beneficial agent into an intravenous delivery system 失效
标题翻译：用于将有益剂引入静脉内输送系统的药筒和适配器
公开(公告)号：US4804366A
公开(公告)日：1989-02-14
申请号：US114817
申请日：1987-10-29
申请人： Brian D. Zdeb , Steven C. Jepson
发明人： Brian D. Zdeb , Steven C. Jepson
IPC分类号： A61M5/168 , A61M5/14 , A61M37/00 , A61M39/00
CPC分类号： A61M5/1409
摘要： A cartridge 444, 644, 744 having a drug or other beneficial agent 608 therein and including an adapter 477 is positioned on a receptacle 442, 642 within a parenteral fluid administration set 420. Also disclosed is an adapter 477' for connecting the receptacle 442, 642 to a chamber 606 having a beneficial agent therein. The cartridge and adapter permit a single opening through the injection site at the receptacle and at the chamber at opposite ends of the flow path means while still permitting simultaneous flow both into and out of the chamber and the receptacle.
摘要翻译：在其中具有药物或其它有益剂608并且包括适配器477的药筒444,644,744位于肠胃外流体给药组420内的容器442,642上。还公开了用于连接容器442的适配器477' 642到其中具有有益剂的室606。墨盒和适配器允许在插座处的注射部位和在流动路径装置的相对端处的腔室处的单个开口，同时允许同时流入和流出腔室和容器。

7. 发明授权

US5049129A Adapter for passive drug delivery system 失效
标题翻译：被动药物输送系统适配器
公开(公告)号：US5049129A
公开(公告)日：1991-09-17
申请号：US514382
申请日：1990-06-04
申请人： Brian D. Zdeb , Glenn L. Slater , Baxter International, Inc.
发明人： Brian D. Zdeb , Glenn L. Slater , Baxter International, Inc.
IPC分类号： A61M5/14
CPC分类号： A61M5/1409
摘要： A medical fluid administration set is disclosed which may be used for the passive reconstitution and delivery of a drug or other beneficial agent with liquid flowing through the administration set. A receptacle mounted in the administration set is adapted for receiving a cartridge containing the beneficial agent. Also disclosed is an adapter for connecting the cartridge and the receptacle and an air flask within the administration set.
摘要翻译：公开了一种药物流体给药装置，其可用于药物或其它有益药剂的被动重建和递送，其中流动通过给药组的液体。安装在管理组件中的插座适于容纳含有有益剂的药筒。还公开了一种用于连接盒和容器的适配器以及管理组内的空气瓶。

8. 发明授权

US4412573A Injection site 失效
标题翻译：注射部位
公开(公告)号：US4412573A
公开(公告)日：1983-11-01
申请号：US335133
申请日：1981-12-28
申请人： Brian D. Zdeb
发明人： Brian D. Zdeb
IPC分类号： B65D33/38 , A61J1/00 , A61J1/05 , A61J1/10 , A61J1/14 , B23P11/02 , B23P19/02 , B29C65/58 , B65D41/50
CPC分类号： A61J1/1406 , B23P11/02 , B23P19/02 , B29C65/58 , B29C66/5344 , B29C66/8322 , A61J1/10 , A61J1/1475 , B29C66/71 , B29K2021/00 , B29L2031/565
摘要： An improved injection site (18) for a medical fluid container (10) is provided, along with a procedure facilitating the automated assembly of the injection site (18). An oversized, compressible situs (22) is retained in compressive relation to a generally tubular port (20) in a manner which makes inadvertent removal of the situs (22) virtually impossible.
摘要翻译：提供了一种用于医疗流体容器（10）的改进的注射部位（18），以及促进注射部位（18）的自动组装的过程。过大的，可压缩的地点（22）以一种使得地形（22）的无意移除实质上不可能的方式与大致管状端口（20）压缩关系保持。

9. 发明授权

US5135500A Self-driven pump device 失效
标题翻译：自驱动泵装置
公开(公告)号：US5135500A
公开(公告)日：1992-08-04
申请号：US429412
申请日：1989-10-31
申请人： Brian D. Zdeb
发明人： Brian D. Zdeb
IPC分类号： A61M5/145
CPC分类号： A61M5/14526 , A61M2005/14513
摘要： An apparatus for delivering fluid with a relatively constant, controlled rate of flow comprises a vacuum power means, a fluid storage means in axial alignment with the vacuum power means and a plunger means carried by the vacuum power means and in axial communication with the fluid storage means. The plunger means is driven by a vacuum which collapses under atmospheric pressure, and as it is driven it effects delivery of the fluid from the fluid storage means.
摘要翻译：用于以相对恒定的受控流速输送流体的装置包括真空动力装置，与真空动力装置轴向对准的流体存储装置和由真空动力装置承载并与流体储存器轴向连通的柱塞装置手段。柱塞装置由在大气压下塌缩的真空驱动，并且当其被驱动时，其实现来自流体存储装置的流体的输送。

10. 发明授权

US5820605A Retractable syringe 失效
标题翻译：伸缩式注射器
公开(公告)号：US5820605A
公开(公告)日：1998-10-13
申请号：US395551
申请日：1995-02-28
申请人： Brian D. Zdeb , Jerry Goldberg
发明人： Brian D. Zdeb , Jerry Goldberg
IPC分类号： A61M5/31 , A61M5/315 , A61M5/32 , A61M5/34 , A61M5/50 , A61M5/00
CPC分类号： A61M5/322 , A61M5/3202 , A61M2005/3104 , A61M2005/31516 , A61M2005/3206 , A61M5/3213 , A61M5/347 , A61M5/502
摘要： A retractable syringe includes a barrel, one end of which comprises a mounting collar. A needle carrier is releasably mounted within the collar and releaseably supports a needle cartridge. A hypodermic needle is mounted within the cartridge. A sheath attaches at one end of the cartridge and at the other end of the collar. A plunger is telescoped into the barrel and includes a piston sealingly engaging the barrel. The piston includes a latch for engaging the carrier and releasing it from the collar. The piston and carrier also include an anti-remount mechanism preventing the carrier from being reengaged into the collar. To preform this, a separate tool is used to insert the carrier into the collar. The plunger further includes surfaces to displace fluid as the piston is forced toward the proximal end of the barrel to displace fluid to reduce squirt. A cap is also provided to initially seal off the proximal end of the barrel and after usage to form a seal by engaging teeth within the proximal end of the barrel.
摘要翻译：可伸缩注射器包括一个筒体，其一端包括安装套环。针托架可释放地安装在套环内并可释放地支撑针筒。皮下注射针安装在药筒内。护套连接在药筒的一端并且在套环的另一端。柱塞可伸缩到筒体中并且包括密封地接合桶的活塞。活塞包括用于接合载体并将其从轴环释放的闩锁。活塞和托架还包括防止托架重新接合到套环中的防重新安装机构。为了预成型，使用单独的工具将载体插入到轴环中。柱塞还包括当活塞被迫朝向筒的近端移动流体以减少喷射时移动流体的表面。还提供盖以最初密封筒的近端并且在使用之后通过接合在筒的近端内的齿形成密封。

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