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1. 发明授权

US5601711A Selective separation filter device 失效
标题翻译：选择性分离过滤装置
公开(公告)号：US5601711A
公开(公告)日：1997-02-11
申请号：US331974
申请日：1994-10-31
申请人： Eric Sklar , Peter L. Graham , Jane Larson
发明人： Eric Sklar , Peter L. Graham , Jane Larson
IPC分类号： B01D21/26 , B01D25/02 , B01D29/05 , B01D27/00
CPC分类号： B01D61/18 , B01D21/262 , B01D25/02 , B01D29/05 , B01D2221/10
摘要： A filter device or apparatus is provided for the separation of materials, especially biomaterials from a fluid sample, under a force such as centrifugation, positive pressure, vacuum, or gravity. The device comprises two or more in-line tubular elements, one or more of which is a module that houses a filter media. The elements have complementary connection structures (e.g., elastomeric seal, O-ring, threads, Luer fittings, compression fittings, bayonet fittings, snap fittings, and the like) such that they can be assembled or reassembled in a train to form a conduit structure for leak-proof passage of a fluid sample volume. The assembly can be disassembled for collection and processing of retentate and filtrate material resulting from the filtration.
摘要翻译：提供了一种过滤装置或装置，用于在诸如离心，正压，真空或重力的作用下，从流体样品中分离材料，特别是生物材料。该装置包括两个或更多个在线管状元件，其中一个或多个是容纳过滤介质的模块。这些元件具有互补的连接结构（例如，弹性体密封件，O形环，螺纹，Luer配件，压缩配件，卡口配件，卡扣配件等），使得它们可以在列车中组装或重新组装以形成导管结构用于流体样品体积的泄漏通过。可以拆卸组件以收集和处理由过滤产生的渗余物和滤液。

2. 外观设计

USD327318S Locking cannula 失效
公开(公告)号：USD327318S
公开(公告)日：1992-06-23
申请号：US419851
申请日：1989-10-10
申请人： Thomas E. Dudar , Michael J. Finley , Peter L. Graham
设计人： Thomas E. Dudar , Michael J. Finley , Peter L. Graham

3. 发明授权

US5100394A Pre-slit injection site 失效
标题翻译：预狭缝注射部位
公开(公告)号：US5100394A
公开(公告)日：1992-03-31
申请号：US425790
申请日：1989-10-23
申请人： Thomas E. Dudar , Steven C. Jepson , Robert P. Dobbie , Peter L. Graham , Michael J. Finley , Richard A. Rollins
发明人： Thomas E. Dudar , Steven C. Jepson , Robert P. Dobbie , Peter L. Graham , Michael J. Finley , Richard A. Rollins
IPC分类号： A61M39/02 , A61J1/00 , A61J1/05 , A61J1/10 , A61J1/14 , A61J1/20 , A61M5/00 , A61M5/162 , A61M25/00 , A61M25/02 , A61M37/00 , A61M39/00 , A61M39/04 , A61M39/14
CPC分类号： A61M5/162 , A61J1/2089 , A61J1/2096 , A61M39/045 , A61M39/14 , A61J1/10 , A61J1/1406 , A61J1/1475 , A61J1/201 , A61J1/2037 , A61J1/2044 , A61J1/2055 , A61J2200/10 , A61M2039/1027 , A61M2039/1033 , A61M2039/1066 , A61M2039/1072 , A61M2039/1077 , A61M2205/195 , A61M2205/197
摘要： A pre-slit injection site includes a housing with a flow path therethrough. A first end of the housing carries a pre-slit septum. A second end of the housing carries a coupling component to adapt the site to standard vials. The coupling component, a vial adapter, includes an adapter spike with openings allowing for the drainage of fluid in the vial through the spike and into the injection site. The vial adapter is provided with a skirt housing unit which protects the adapter spike in manufacturing and use. The skirt housing unit also provides features to lockingly engage the adapter with injection site to standard vials, despite dimensional variations in vial closures. Another embodiment of the coupling component is a spike having a barb feature capable of insertion into a standard vial or port and resisting disengagement.A blunt cannula is usable with the injection site combined with the coupling components.
摘要翻译：预狭缝注射部位包括具有穿过其中的流动通道的壳体。外壳的第一端装有预狭缝隔膜。外壳的第二端带有耦合部件，以使现场符合标准样品瓶。耦合部件，小瓶适配器，包括具有开口的适配器尖端，允许小瓶中的流体通过尖峰排出并进入注射部位。小瓶适配器设置有裙部壳体单元，其在制造和使用中保护适配器尖峰。裙部外壳单元还提供将适配器与注射部位锁定接合到标准小瓶的特征，尽管瓶盖关闭时尺寸变化。耦合部件的另一实施例是具有能够插入到标准小瓶或端口中并具有抵抗分离的倒钩特征的钉。钝头套管可用于与联接部件组合的注射部位。

4. 发明授权

US5776125A Needleless vial access device 失效
标题翻译：无针管进样装置
公开(公告)号：US5776125A
公开(公告)日：1998-07-07
申请号：US427063
申请日：1995-04-24
申请人： Thomas E. Dudar , Peter L. Graham , Steven C. Jepson
发明人： Thomas E. Dudar , Peter L. Graham , Steven C. Jepson
IPC分类号： A61J3/00 , A61J1/00 , A61J1/14 , A61J1/20 , A61M5/162 , A61M5/32 , A61M5/34 , A61M39/04 , A61M39/14 , A61M37/00
CPC分类号： A61J1/2089 , A61J1/2096 , A61M39/045 , A61M39/14 , A61M5/162 , A61J1/1406 , A61J1/201 , A61J2200/10 , A61M2005/3201 , A61M2039/1072 , A61M2205/195 , A61M2205/197
摘要： The present invention provides a piercing member adapted for use with a flow channel. The piercing member has a penetrating member for piercing a solid closure, and is retained to the flow channel, but still allows fluid to flow through the flow channel while retained to the flow channel.
摘要翻译：本发明提供一种适于与流动通道一起使用的穿孔构件。刺穿构件具有用于刺穿固体闭合件的穿透构件，并且保持在流动通道中，但是仍然允许流体在保持流动通道的同时流过流动通道。

5. 发明授权

US5211638A Pre-slit injection site 失效
标题翻译：预狭缝注射部位
公开(公告)号：US5211638A
公开(公告)日：1993-05-18
申请号：US823498
申请日：1992-01-21
申请人： Thomas E. Dudar , Steven C. Jepson , Robert P. Dobbie , Peter L. Graham , Michael J. Finley , Richard A. Rollins
发明人： Thomas E. Dudar , Steven C. Jepson , Robert P. Dobbie , Peter L. Graham , Michael J. Finley , Richard A. Rollins
IPC分类号： A61M39/02 , A61J1/00 , A61J1/05 , A61J1/10 , A61J1/14 , A61J1/20 , A61M5/00 , A61M5/162 , A61M25/00 , A61M25/02 , A61M37/00 , A61M39/00 , A61M39/04 , A61M39/14
CPC分类号： A61M5/162 , A61J1/2089 , A61J1/2096 , A61M39/045 , A61M39/14 , A61J1/10 , A61J1/1406 , A61J1/1475 , A61J1/201 , A61J1/2037 , A61J1/2044 , A61J1/2055 , A61J2200/10 , A61M2039/1072 , A61M2039/1077 , A61M2205/195 , A61M2205/197
摘要： A pre-slit injection site includes a housing with a flow path therethrough. A first end of the housing carries a pre-slit septum. A second end of the housing carries a coupling component to adapt the site to standard vials. The coupling component, a vial adapter, includes an adapter spike with openings allowing for the drainage of fluid in the vial through the spike and into the injection site. The vial adapter is provided with a skirt housing unit which protects the adapter spike in manufacturing and use. The skirt housing unit also provides features to lockingly engage the adapter with injection site to standard vials, despite dimensional variations in vial closures. Another embodiment of the coupling component is a spike having a barb feature capable of insertion into a standard vial or port and resisting disengagement.A blunt cannula is usable with the injection site combined with the coupling components.
摘要翻译：预狭缝注射部位包括具有穿过其中的流动通道的壳体。外壳的第一端装有预狭缝隔膜。外壳的第二端带有耦合部件，以使现场符合标准样品瓶。耦合部件，小瓶适配器，包括具有开口的适配器尖端，允许小瓶中的流体通过尖峰排出并进入注射部位。小瓶适配器设置有裙部壳体单元，其在制造和使用中保护适配器尖峰。裙部外壳单元还提供将适配器与注射部位锁定接合到标准小瓶的特征，尽管瓶盖关闭时尺寸变化。耦合部件的另一实施例是具有能够插入到标准小瓶或端口中并具有抵抗分离的倒钩特征的钉。钝头套管可用于与联接部件组合的注射部位。

6. 发明授权

US5411499A Needleless vial access device 失效
标题翻译：无针管进样装置
公开(公告)号：US5411499A
公开(公告)日：1995-05-02
申请号：US737735
申请日：1991-07-30
申请人： Thomas E. Dudar , Peter L. Graham , Steven C. Jepson
发明人： Thomas E. Dudar , Peter L. Graham , Steven C. Jepson
IPC分类号： A61J3/00 , A61J1/00 , A61J1/14 , A61J1/20 , A61M5/162 , A61M5/32 , A61M5/34 , A61M39/04 , A61M39/14 , A61M37/00
CPC分类号： A61J1/2089 , A61J1/2096 , A61M39/045 , A61M39/14 , A61M5/162 , A61J1/1406 , A61J1/201 , A61J2200/10 , A61M2005/3201 , A61M2039/1072 , A61M2205/195 , A61M2205/197
摘要： A cannula assembly adapted to pierce a solid or unslit closure is disclosed and includes a blunt cannula and a piercing member held in cooperation with or contained within the flow channel of the cannula. Generally, the piercing member includes a tip capable of piercing an unslit stopper or closure and a means to temporarily retain the piercing member from the cannula and prevent inadvertent disengagement of the piercing member from the blunt cannula.
摘要翻译：公开了一种适于穿透固体或未照明的封闭物的插管组件，其包括与套管的流动通道配合或包含在套管的流动通道内的钝性插管和刺穿构件。通常，刺穿构件包括能够刺穿未点燃的止动器或闭合件的尖端以及临时将穿刺构件从套管保持的装置，并且防止刺穿构件与钝头插管无意中脱离接触。

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