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1. 发明授权

US09097631B2 Apparatus and method for processing biological material 有权
公开(公告)号：US09097631B2
公开(公告)日：2015-08-04
申请号：US13616269
申请日：2012-09-14
申请人： Kyungyoon Min , Thomas E. Dudar , James C. Laird
发明人： Kyungyoon Min , Thomas E. Dudar , James C. Laird
IPC分类号： B01D21/00 , B01D21/26 , G01N1/40 , C12N5/07 , C12M1/00 , G01N15/04 , B01L3/00 , G01N21/07 , A61M39/04 , A61M39/26
CPC分类号： G01N1/4077 , A61M39/045 , A61M39/26 , B01D21/26 , B01D21/262 , B01L1/00 , B01L3/502 , B01L3/5021 , B01L3/5027 , B01L3/50273 , B01L3/502738 , B01L3/502753 , B01L3/50825 , B01L3/5635 , B01L2200/025 , B01L2200/026 , B01L2200/027 , B01L2200/0621 , B01L2200/0647 , B01L2200/10 , B01L2300/044 , B01L2300/046 , B01L2300/049 , B01L2400/0409 , B01L2400/0478 , B01L2400/0481 , B01L2400/0633 , C12M47/02 , G01N1/40 , G01N15/042 , G01N21/03 , G01N21/07 , G01N33/491 , G01N2001/4083 , G01N2015/149 , G01N2035/00495 , G01N2035/1058
摘要： The application discloses an apparatus and method for processing biological material, including a suspension of cells.

2. 发明授权

US06605076B1 Pre-slit injection site and tapered cannula 失效
公开(公告)号：US06605076B1
公开(公告)日：2003-08-12
申请号：US08699083
申请日：1996-08-09
申请人： Steven C. Jepson , Thomas E. Dudar , Brian D. Zdeb , Vince C. Desecki
发明人： Steven C. Jepson , Thomas E. Dudar , Brian D. Zdeb , Vince C. Desecki
IPC分类号： A61M2516
CPC分类号： A61M39/1011 , A61J1/10 , A61J1/1406 , A61J1/1475 , A61J1/201 , A61J1/2037 , A61J1/2044 , A61J1/2055 , A61J1/2089 , A61J1/2096 , A61J2200/10 , A61M5/162 , A61M39/045 , A61M39/14 , A61M2039/1033 , A61M2039/1072 , A61M2039/1077 , A61M2205/195 , A61M2205/197
摘要： A pre-slit injection site includes a housing with a flow path therethrough. A first end of the housing carries a pre-slit septum. One form of a blunt cannula, usable with the injection site, carries a locking member. When the pre-slit injection site slidably receives the blunt cannula, the locking member latches to the injection site and creates a mechanically coupled unit. Another form of the cannula includes a tube having a tapered distal end region and having elongate discharge slots for reducing contact surface area and for directing the flow laterally out of the cannula. The cannula may also include a rounded lead post, an annular barb, and axially oriented grooves.

3. 发明授权

US06447498B1 Pre-slit injection site and tapered cannula 失效
标题翻译：预切口注射部位和锥形插管
公开(公告)号：US06447498B1
公开(公告)日：2002-09-10
申请号：US09182571
申请日：1998-10-29
申请人： Steven C. Jepson , Thomas E. Dudar , Brian D. Zdeb , Vince C. Desecki
发明人： Steven C. Jepson , Thomas E. Dudar , Brian D. Zdeb , Vince C. Desecki
IPC分类号： A61M532
CPC分类号： A61M39/1011 , A61J1/10 , A61J1/1406 , A61J1/1475 , A61J1/201 , A61J1/2037 , A61J1/2044 , A61J1/2055 , A61J1/2089 , A61J1/2096 , A61J2200/10 , A61M5/162 , A61M39/045 , A61M39/14 , A61M2039/1033 , A61M2039/1072 , A61M2039/1077 , A61M2205/195 , A61M2205/197
摘要： A pre-slit injection site includes a housing with a flow path therethrough. A first end of the housing carries a pre-slit septum. One form of a blunt cannula, usable with the injection site, carries a locking member. When the pre-slit injection site slidably receives the blunt cannula, the locking member latches to the injection site and creates a mechanically coupled unit. Another form of the cannula includes a tube having a tapered distal end region and having elongate discharge slots for reducing contact surface area and for directing the flow laterally out of the cannula. The cannula may also include a rounded lead post, an annular barb, and axially oriented grooves.
摘要翻译：预狭缝注射部位包括具有穿过其中的流动通道的壳体。外壳的第一端装有预狭缝隔膜。与注射部位一起使用的钝性插管的一种形式携带锁定构件。当预狭缝注射部位可滑动地接收钝头套管时，锁定构件锁定到注射部位并产生机械耦合单元。套管的另一种形式包括具有锥形远端区域并且具有用于减少接触表面积并用于将流体横向导出套管的细长排出槽的管。套管还可以包括圆形引导柱，环形倒钩和轴向定向的凹槽。

4. 发明授权

US5964785A Bayonet look cannula for pre-slit y-site 失效
标题翻译：用于预切口y位点的卡口套管
公开(公告)号：US5964785A
公开(公告)日：1999-10-12
申请号：US486119
申请日：1995-06-07
申请人： Vincent C. Desecki , Thomas E. Dudar , Michael J. Finley
发明人： Vincent C. Desecki , Thomas E. Dudar , Michael J. Finley
IPC分类号： A61M39/02 , A61J1/00 , A61J1/05 , A61J1/10 , A61J1/14 , A61J1/20 , A61M5/00 , A61M5/162 , A61M25/00 , A61M25/02 , A61M37/00 , A61M39/00 , A61M39/04 , A61M39/14 , A61M29/00
CPC分类号： A61M5/162 , A61J1/2089 , A61J1/2096 , A61M39/045 , A61M39/14 , A61J1/10 , A61J1/1406 , A61J1/1475 , A61J1/201 , A61J1/2058 , A61M2039/1033 , A61M2039/1066 , A61M2039/1072 , A61M2205/195 , A61M2205/197 , Y10S604/905
摘要： A cannula and injection site coupling system comprising a cannula or piercing member assembly having a blunt cannula partially surrounded by a protective shield. The protective shield is spaced apart from the blunt cannula and includes a bayonet arm, a bayonet barb, a bayonet lock and an opening or gap. The injection site has a septum with a opening and an arm. When the cannula assembly and injection site are coupled, the injection site arm is lodged within the cannula assembly lock opening.
摘要翻译：插管和注射部位联接系统，其包括套管或刺穿构件组件，其具有由保护罩部分地围绕的钝头套管。防护罩与钝头插管间隔开，包括卡口臂，卡口倒钩，卡口锁和开口或间隙。注射部位有一个开口和一个手臂的隔膜。当套管组件和注射部位联接时，注射部位臂被放置在套管组件锁定开口内。

5. 发明授权

US5776125A Needleless vial access device 失效
标题翻译：无针管进样装置
公开(公告)号：US5776125A
公开(公告)日：1998-07-07
申请号：US427063
申请日：1995-04-24
申请人： Thomas E. Dudar , Peter L. Graham , Steven C. Jepson
发明人： Thomas E. Dudar , Peter L. Graham , Steven C. Jepson
IPC分类号： A61J3/00 , A61J1/00 , A61J1/14 , A61J1/20 , A61M5/162 , A61M5/32 , A61M5/34 , A61M39/04 , A61M39/14 , A61M37/00
CPC分类号： A61J1/2089 , A61J1/2096 , A61M39/045 , A61M39/14 , A61M5/162 , A61J1/1406 , A61J1/201 , A61J2200/10 , A61M2005/3201 , A61M2039/1072 , A61M2205/195 , A61M2205/197
摘要： The present invention provides a piercing member adapted for use with a flow channel. The piercing member has a penetrating member for piercing a solid closure, and is retained to the flow channel, but still allows fluid to flow through the flow channel while retained to the flow channel.
摘要翻译：本发明提供一种适于与流动通道一起使用的穿孔构件。刺穿构件具有用于刺穿固体闭合件的穿透构件，并且保持在流动通道中，但是仍然允许流体在保持流动通道的同时流过流动通道。

6. 发明授权

US5531711A Safety cannula 失效
公开(公告)号：US5531711A
公开(公告)日：1996-07-02
申请号：US376727
申请日：1995-01-23
申请人： Kurt Attermeier , Thomas E. Dudar , Mark A. Stiehl , Joseph M. Tartaglia
发明人： Kurt Attermeier , Thomas E. Dudar , Mark A. Stiehl , Joseph M. Tartaglia
IPC分类号： A61J1/05 , A61M5/24 , A61M37/00 , A61M39/00 , A61M39/04 , A61M39/14 , A61M5/00
CPC分类号： A61M5/24 , A61M39/045 , A61M2005/2414 , A61M2005/247 , Y10S604/905
摘要： A coupling system for transferring fluids from a medicament-containing cartridge to an injection site comprises a fluid flow channel, a blunt cannula defining the distal end of the fluid flow channel, a needle cannula defining the proximal end of the fluid flow channel, and means for fixedly connecting the needle cannula to the blunt cannula.

7. 发明授权

US5188620A Pre-slit injection site and associated cannula 失效
标题翻译：预切口注射部位和相关插管
公开(公告)号：US5188620A
公开(公告)日：1993-02-23
申请号：US539278
申请日：1990-06-14
申请人： Steve C. Jepson , Thomas E. Dudar
发明人： Steve C. Jepson , Thomas E. Dudar
IPC分类号： A61M39/02 , A61J1/00 , A61J1/05 , A61J1/10 , A61J1/14 , A61J1/20 , A61M5/00 , A61M5/162 , A61M25/00 , A61M25/02 , A61M37/00 , A61M39/00 , A61M39/04 , A61M39/14
CPC分类号： A61J1/2089 , A61J1/2096 , A61M39/045 , A61M39/14 , A61M5/162 , A61J1/10 , A61J1/1406 , A61J1/1475 , A61J1/201 , A61J1/2037 , A61J1/2044 , A61J1/2055 , A61J2200/10 , A61M2039/1072 , A61M2039/1077 , A61M2205/195 , A61M2205/197 , Y10S604/905
摘要： A pre-slit injection site includes a housing with a flow path therethrough. A first end of the housing carries a pre-slit septum. A blunt cannula, usable with the injection site, carries a locking member. When the pre-slit injection site slidably receives the blunt cannula the locking member latches to the injection site forming a mechanically coupled unit.
摘要翻译：预狭缝注射部位包括具有穿过其中的流动通道的壳体。外壳的第一端装有预狭缝隔膜。可与注射部位一起使用的钝插管承载锁定构件。当预狭缝注射部位可滑动地接收钝头套管时，锁定构件闩锁到注射部位，形成机械耦合单元。

8. 发明授权

US09176038B2 Apparatus and method for processing biological material 有权
标题翻译：用于处理生物材料的装置和方法
公开(公告)号：US09176038B2
公开(公告)日：2015-11-03
申请号：US13611211
申请日：2012-09-12
申请人： Kyungyoon Min , Thomas E. Dudar , James C. Laird
发明人： Kyungyoon Min , Thomas E. Dudar , James C. Laird
IPC分类号： B01L3/00 , B01D21/00 , B01D21/26 , C12M1/00 , G01N1/40 , G01N15/04 , G01N21/07 , B01L1/00 , G01N15/14 , G01N21/03 , G01N35/10 , A61M39/04 , A61M39/26
CPC分类号： G01N1/4077 , A61M39/045 , A61M39/26 , B01D21/26 , B01D21/262 , B01L1/00 , B01L3/502 , B01L3/5021 , B01L3/5027 , B01L3/50273 , B01L3/502738 , B01L3/502753 , B01L3/50825 , B01L3/5635 , B01L2200/025 , B01L2200/026 , B01L2200/027 , B01L2200/0621 , B01L2200/0647 , B01L2200/10 , B01L2300/044 , B01L2300/046 , B01L2300/049 , B01L2400/0409 , B01L2400/0478 , B01L2400/0481 , B01L2400/0633 , C12M47/02 , G01N1/40 , G01N15/042 , G01N21/03 , G01N21/07 , G01N33/491 , G01N2001/4083 , G01N2015/149 , G01N2035/00495 , G01N2035/1058
摘要： The application discloses an apparatus and method for processing biological material, including a suspension of cells.
摘要翻译：本申请公开了一种用于处理生物材料的装置和方法，包括细胞悬浮液。

9. 发明申请

US20100160889A1 VIAL ACCESS SPIKE ASSEMBLY 审中-公开
标题翻译： VIAL ACCESS SPIKE总成
公开(公告)号：US20100160889A1
公开(公告)日：2010-06-24
申请号：US12341473
申请日：2008-12-22
申请人： Donald A. Smith , Steven C. Jepson , Thomas E. Dudar
发明人： Donald A. Smith , Steven C. Jepson , Thomas E. Dudar
IPC分类号： A61J1/14
CPC分类号： A61J1/2096 , A61J1/201 , A61J1/2055
摘要： A spike assembly having an elongate spike defining a hollow cannula that is in fluid communication with the interior of a luer connection portion. The spike assembly provides needleless access to a stopper of a vial to facilitate injection and withdrawal of fluids via a syringe barrel selectively secured to the luer connection portion. The syringe can safely be removed from the spike assembly and then be directly attached to a luer compatible connector. The elongate spike may include a frangible tip portion that can break away from the spike assembly within a vial. The spike assembly may have a neck with a pair of gripping wing members. The spike assembly may have a feature that prevents rotation of the spike in the vial stopper, thereby allowing the syringe to be easily and safely disconnected from the spike assembly without having to grasp the spike assembly.
摘要翻译：尖钉组件，其具有限定中空插管的细长尖端，其与鲁尔连接部分的内部流体连通。尖钉组件提供对瓶的塞子的无针入口，以便于通过选择性地固定到鲁尔连接部分的注射器筒的注射和抽出流体。注射器可以安全地从尖钉组件移除，然后直接连接到鲁尔兼容连接器。细长的尖钉可以包括易碎的尖端部分，其可以在小瓶内脱离尖钉组件。尖钉组件可以具有带有一对夹持翼构件的颈部。尖钉组件可以具有防止瓶塞中的尖头旋转的特征，从而允许注射器容易且安全地从尖钉组件断开，而不必抓住尖钉组件。

10. 发明授权

US06213996B1 Pre-slit injection site and tapered cannula 失效
公开(公告)号：US06213996B1
公开(公告)日：2001-04-10
申请号：US09182260
申请日：1998-10-29
申请人： Steven C. Jepson , Thomas E. Dudar , Michael J. Finley , Vincent C. Desecki
发明人： Steven C. Jepson , Thomas E. Dudar , Michael J. Finley , Vincent C. Desecki
IPC分类号： A61M2500
CPC分类号： A61J1/2089 , A61J1/10 , A61J1/1406 , A61J1/1475 , A61J1/201 , A61J1/2055 , A61J1/2096 , A61M5/162 , A61M39/045 , A61M39/1011 , A61M39/14 , A61M2039/1033 , A61M2039/1066 , A61M2039/1072 , A61M2205/195 , A61M2205/197 , Y10S604/905
摘要： A pre-slit injection site (34) includes a housing (40) with a flow path therethrough. A first end (42) of the housing (40) carries a pre-slit septum (52). One form of a blunt cannula (98), usable with the injection site (34), carries a locking member (100). When the pre-slit injection site (34) slidably receives the blunt cannula (98), the locking member (100) latches to the injection site (34) and creates a mechanically coupled unit. Another form of the cannula (280) includes a tube having a tapered distal end region (298) and having elongate discharge slots (294) for reducing contact surface area and for directing the flow laterally out of the cannula. The cannula may also include a rounded lead post (330), an annular barb (394), and axially oriented grooves (268).

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