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1. 发明授权

US08131365B2 Event-based battery monitor for implantable devices 有权
标题翻译：基于事件的可植入式电池监视器
公开(公告)号：US08131365B2
公开(公告)日：2012-03-06
申请号：US12492416
申请日：2009-06-26
申请人： Cheng Zhang , Keith R. Maile
发明人： Cheng Zhang , Keith R. Maile
IPC分类号： A61N1/00
CPC分类号： A61N1/378 , A61N1/3708 , A61N1/37288 , G01R31/362 , G01R31/3648
摘要： A remaining charge capacity of a battery having an initial charge capacity is monitored. The battery powers a remote implantable medical device (IMD) that includes an active state, during which the remote IMD performs at least one function, and an inactive state, during which the remote IMD performs no functions. An active state charge consumption is computed based on stored parameters associated with an operational charge consumption for each function, and an inactive state charge consumption is computed based on a leakage current associated with the inactive state and a time the remote IMD is in the inactive state. The active state charge consumption and inactive state charge consumption are subtracted from the initial charge capacity to determine the remaining charge capacity.
摘要翻译：监视具有初始充电容量的电池的剩余充电容量。电池为远程可植入医疗设备（IMD）供电，该远程可植入医疗设备（IMD）包括活动状态，在该状态期间，远程IMD执行至少一个功能，以及非活动状态，在该状态期间，远程IMD不执行功能。基于与每个功能的操作电荷消耗相关联的存储参数来计算活动状态电荷消耗，并且基于与非活动状态相关联的泄漏电流和远程IMD处于非活动状态的时间来计算非活动状态电荷消耗。从初始充电容量中减去活动状态电荷消耗和无效状态电荷消耗，以确定剩余充电容量。

2. 发明授权

US07570998B2 Acoustic communication transducer in implantable medical device header 有权
标题翻译：可植入医疗器械头部的声学通讯传感器
公开(公告)号：US07570998B2
公开(公告)日：2009-08-04
申请号：US11780903
申请日：2007-07-20
申请人： Cheng Zhang , Thomas W. Piaget , Abhijeet V. Chavan , Keith R. Maile , Ron A. Balczewski
发明人： Cheng Zhang , Thomas W. Piaget , Abhijeet V. Chavan , Keith R. Maile , Ron A. Balczewski
IPC分类号： A61N1/00
CPC分类号： A61N1/37217 , A61B5/0028 , A61B5/0031 , A61B5/021 , A61B5/14532 , A61B8/4281
摘要： An implantable medical device is adapted for implantation into body tissue. The implantable medical device comprises a housing and a header coupled to the housing. A cavity is located in the header. An ultrasonic transducer adapted to transmit acoustic waves at a communication frequency is located in the cavity, and a coupling surface is interposed between the ultrasonic transducer and the body tissue and is acoustically coupled with the body tissue.
摘要翻译：可植入医疗装置适于植入人体组织。可植入医疗装置包括壳体和联接到壳体的头部。一个空腔位于头部。适于以通信频率传输声波的超声波换能器位于空腔中，并且耦合表面插入在超声换能器和身体组织之间并与身体组织进行声学耦合。

3. 发明授权

US08777863B2 Implantable medical device with internal piezoelectric energy harvesting 有权
标题翻译：具有内部压电能量收集的植入式医疗器械
公开(公告)号：US08777863B2
公开(公告)日：2014-07-15
申请号：US12774976
申请日：2010-05-06
申请人： Thomas W. Piaget , Bin Mi , Lance E. Juffer , Keith R. Maile , Abhijeet V. Chavan , Cheng Zhang
发明人： Thomas W. Piaget , Bin Mi , Lance E. Juffer , Keith R. Maile , Abhijeet V. Chavan , Cheng Zhang
IPC分类号： A61B5/02
CPC分类号： H01L41/1138 , A61B5/0031 , A61B5/0215 , H02N2/18
摘要： Methods, systems, and apparatus for powering and/or recharging medical devices implanted within the body are described. An illustrative power generation module disposable within the interior space of an implantable medical device includes a module body that defines an interior cavity as well as a flexible diaphragm that spans the interior cavity. The flexible diaphragm includes a first electrical conductor, a piezoelectric layer disposed adjacent to the first electrical conductor, and a second electrical conductor disposed adjacent to the piezoelectric layer. The piezoelectric layer is configured to displace within the interior cavity and generate a voltage differential between the first electrical conductor and the second electrical conductor.
摘要翻译：描述了植入体内的医疗装置的供电和/或再充电的方法，系统和装置。在可植入医疗装置的内部空间内可放置的说明性发电模块包括限定内腔的模块主体以及跨越内腔的柔性隔膜。柔性隔膜包括第一电导体，邻近第一电导体设置的压电层和邻近压电层设置的第二电导体。压电层被配置为在内腔内移位，并在第一电导体和第二电导体之间产生电压差。

4. 发明授权

US08060214B2 Implantable medical device with inductive coil configurable for mechanical fixation 有权
标题翻译：具有感应线圈的可植入医疗器械可配置用于机械固定
公开(公告)号：US08060214B2
公开(公告)日：2011-11-15
申请号：US11326802
申请日：2006-01-05
申请人： Dennis E. Larson , Cheng Zhang , Keith R. Maile , Abhi V. Chavan
发明人： Dennis E. Larson , Cheng Zhang , Keith R. Maile , Abhi V. Chavan
IPC分类号： A61N1/00 , A61N1/08
CPC分类号： A61N1/3787 , A61B5/0031 , A61N1/37223
摘要： An embodiment of a system for gathering physiologic data related to a human body includes a sensor device implanted in the human body, an inductive coil communicably coupled to the implanted sensor device; and a manager device in communication with the implanted sensor device via the inductive coil. The coil may be wrapped around the sensor device or attached to the sensor device fixation. An embodiment of a method for gathering physiologic data related to a physiologic parameter in a human body includes communicably coupling an inductive coil to communication circuitry of an implantable medical device (IMD), deploying the inductive coil and the IMD into a vessel of the human body, and inducing current in the inductive coil via the communication circuitry, the current representative of data associated with the IMD.
摘要翻译：用于收集与人体相关的生理数据的系统的实施例包括植入人体内的传感器装置，可感知地耦合到植入的传感器装置的感应线圈; 以及经由感应线圈与植入的传感器装置通信的管理器装置。线圈可以缠绕在传感器装置上或附接到传感器装置固定。用于收集与人体生理参数相关的生理数据的方法的实施例包括将感应线圈可通信地耦合到可植入医疗设备（IMD）的通信电路，将感应线圈和IMD部署到人体的容器中，并且经由通信电路感应电感线圈中的电流，表示与IMD相关联的数据的电流。

5. 发明申请

US20100317977A1 IMPLANTABLE MEDICAL DEVICE WITH INTERNAL PIEZOELECTRIC ENERGY HARVESTING 有权
标题翻译：具有内部压电能量收集的可植入医疗器械
公开(公告)号：US20100317977A1
公开(公告)日：2010-12-16
申请号：US12774976
申请日：2010-05-06
申请人： Thomas W. Piaget , Bin Mi , Lance E. Juffer , Keith R. Maile , Abhijeet V. Chavan , Cheng Zhang
发明人： Thomas W. Piaget , Bin Mi , Lance E. Juffer , Keith R. Maile , Abhijeet V. Chavan , Cheng Zhang
IPC分类号： A61B5/0215 , H02N2/18
CPC分类号： H01L41/1138 , A61B5/0031 , A61B5/0215 , H02N2/18
摘要： Methods, systems, and apparatus for powering and/or recharging medical devices implanted within the body are described. An illustrative power generation module disposable within the interior space of an implantable medical device includes a module body that defines an interior cavity as well as a flexible diaphragm that spans the interior cavity. The flexible diaphragm includes a first electrical conductor, a piezoelectric layer disposed adjacent to the first electrical conductor, and a second electrical conductor disposed adjacent to the piezoelectric layer. The piezoelectric layer is configured to displace within the interior cavity and generate a voltage differential between the first electrical conductor and the second electrical conductor.
摘要翻译：描述了植入体内的医疗装置的供电和/或再充电的方法，系统和装置。在可植入医疗装置的内部空间内可放置的说明性发电模块包括限定内腔的模块主体以及跨越内腔的柔性隔膜。柔性隔膜包括第一电导体，邻近第一电导体设置的压电层和邻近压电层设置的第二电导体。压电层被配置为在内腔内移位，并在第一电导体和第二电导体之间产生电压差。

6. 发明授权

US07813801B2 Implantable medical device powered by rechargeable battery 有权
标题翻译：由可充电电池供电的植入式医疗设备
公开(公告)号：US07813801B2
公开(公告)日：2010-10-12
申请号：US11610894
申请日：2006-12-14
申请人： Nick A. Youker , Robert S. Harguth , Keith R. Maile , Michael J. Root , Cheng Zhang , Abhi Chavan , Paul Huelskamp
发明人： Nick A. Youker , Robert S. Harguth , Keith R. Maile , Michael J. Root , Cheng Zhang , Abhi Chavan , Paul Huelskamp
IPC分类号： A61N1/00
CPC分类号： A61N1/3787
摘要： A battery management circuit provides an implantable medical device with power management that allows safe and efficient use of a rechargeable battery. Various ways of monitoring the energy level of the rechargeable battery and controlling the battery recharging process for user convenience and safety are provided.
摘要翻译：电池管理电路提供具有电源管理的可植入医疗设备，其允许安全且有效地使用可充电电池。提供了监视可再充电电池的能量水平和控制电池充电过程以便用户方便和安全的各种方式。

7. 发明授权

US07650185B2 System and method for walking an implantable medical device from a sleep state 有权
标题翻译：从植入式医疗装置从睡眠状态走路的系统和方法
公开(公告)号：US07650185B2
公开(公告)日：2010-01-19
申请号：US11380112
申请日：2006-04-25
申请人： Keith R. Maile , Abhijeet V. Chavan , Von Arx A. Jeffrey , Cheng Zhang
发明人： Keith R. Maile , Abhijeet V. Chavan , Von Arx A. Jeffrey , Cheng Zhang
IPC分类号： A61N1/362
CPC分类号： A61N1/37252 , A61B5/0031 , A61B2560/0209 , A61N1/3706 , A61N1/37217 , A61N1/37264 , A61N1/37288
摘要： A system and method for waking up an implantable medical device (“IMD”) from a sleep state in which power consumption by the IMD is essentially zero. The IMD may be adapted to perform one or more designated measurement and/or therapeutic functions. In one embodiment, the IMD includes a wake-up sensor that is adapted to sense the presence or absence of a wake-up field generated by another IMD or an external device. The wake-up field may, in some embodiments, be an electromagnetic field, a magnetic field, or a physiologically sub-threshold excitation current (i.e., E-field). Upon sensing by the wake-up sensor of the wake-up field, other components of the IMD, which may include a controller, a sensing and/or therapy module, and/or a communications module, are awakened to perform one or more designated functions.
摘要翻译：一种用于将可植入医疗装置（“IMD”）从睡眠状态唤醒的系统和方法，其中IMD的功率消耗基本为零。 IMD可以适于执行一个或多个指定的测量和/或治疗功能。在一个实施例中，IMD包括适于感测由另一IMD或外部设备产生的唤醒场的存在或不存在的唤醒传感器。在一些实施例中，唤醒场可以是电磁场，磁场或生理学亚阈值激励电流（即，电场）。唤醒传感器感应唤醒场后，可以包括控制器，感测和/或治疗模块和/或通信模块的IMD的其他部件被唤醒以执行一个或多个指定的功能。

8. 外观设计

USD1020017S1 Belt light 有权
公开(公告)号：USD1020017S1
公开(公告)日：2024-03-26
申请号：US29834373
申请日：2022-04-11
申请人： Cheng Zhang
设计人： Cheng Zhang
摘要： FIG. 1 is a perspective view of a belt light showing my new design;
FIG. 2 is a front elevational view thereof;
FIG. 3 is a rear elevational view thereof;
FIG. 4 is a left side elevational view thereof;
FIG. 5 is a right side elevational view thereof;
FIG. 6 is a top plan view thereof; and,
FIG. 7 is a bottom plan view thereof.
The broken lines throughout the drawing figures depict portions of the belt light that form no part of the claimed design.

9. 发明申请

US20140258496A1 DATA CENTRE SYSTEM AND METHOD FOR A DATA CENTRE TO PROVIDE SERVICE 有权
标题翻译：数据中心系统和数据中心提供服务的方法
公开(公告)号：US20140258496A1
公开(公告)日：2014-09-11
申请号：US14346653
申请日：2012-07-17
申请人： Jiaoren Wu , Tao Liu , Ning Liu , Cheng Zhang , Jiang Fu
发明人： Jiaoren Wu , Tao Liu , Ning Liu , Cheng Zhang , Jiang Fu
IPC分类号： H04L12/803
CPC分类号： H04L47/125 , H04L29/06 , H04L61/1511 , H04L61/251 , H04L61/2528 , H04L61/6086 , H04L67/1002 , H04L67/1023
摘要： A data center system and a method for a data center to provide service are provided. The data center system comprises at least one first load balancing device, a plurality of second load balancing devices, and a plurality of servers. The first load balancing device is configured to transmit the first type network request to one of the plurality of second load balancing devices with a first scheduling strategy. The second load balancing device is configured to convert the first type network request to a second type network request, and to transmit the second type network request after the source address and destination address translation to one of the plurality of servers with a second scheduling strategy. The server is configured to generate a second type network response according to the second type network request and to return the second type network response to a corresponding second load balancing device.
摘要翻译：提供数据中心系统和数据中心提供服务的方法。数据中心系统包括至少一个第一负载平衡装置，多个第二负载平衡装置和多个服务器。第一负载平衡装置被配置为以第一调度策略将第一类型网络请求发送到多个第二负载平衡装置之一。第二负载平衡装置被配置为将第一类型网络请求转换为第二类型网络请求，并且在源地址和目的地地址转换之后，以第二调度策略向多个服务器之一发送第二类型网络请求。服务器被配置为根据第二类型网络请求生成第二类型网络响应，并且将第二类型网络响应返回到对应的第二负载平衡设备。

10. 发明申请

US20130231369A1 1-[(4-hydroxypiperidin-4-yl)methyl]pyridin-2(1H)-one derivatives, preparation methods and uses thereof 有权
标题翻译： 1 - [（4-羟基哌啶-4-基）甲基]吡啶-2（1H） - 酮衍生物，其制备方法和用途
公开(公告)号：US20130231369A1
公开(公告)日：2013-09-05
申请号：US13697857
申请日：2011-04-08
申请人： Yunfeng Li , Rifang Yang , Youzhi Zhang , Yongzhen Li , Zengliang Jin , Peng Li , Li Yuan , Liuhong Yun , Nan Zhao , Cheng Zhang , Xiaodan Xu , Rusheng Zhao , Hongxia Chen , Rui Xue , Juanjuan Qin , Zhenzhen Wang , Jiazhi Yao
发明人： Yunfeng Li , Rifang Yang , Youzhi Zhang , Yongzhen Li , Zengliang Jin , Peng Li , Li Yuan , Liuhong Yun , Nan Zhao , Cheng Zhang , Xiaodan Xu , Rusheng Zhao , Hongxia Chen , Rui Xue , Juanjuan Qin , Zhenzhen Wang , Jiazhi Yao
IPC分类号： C07D401/06
CPC分类号： C07D401/06
摘要： Provided are N-[(4-hydroxypiperidin-4-yl)methyl]pyridin-2(1H)-one derivatives represented by formula I, stereoisomers, pharmaceutically acceptable salts or solvates thereof. The above compounds have the dual activities of 5-hydroxytryptamine 1A receptor ligand and selective serotonin reuptake inhibitor. The preparation methods of the above compounds, the uses of these compounds for the prevention or treatment of nervous system diseases related to 5-hydroxytryptamine system dysfunction and the pharmaceutical compositions containing these compounds are also provided.
摘要翻译：提供由式I表示的N - [（4-羟基哌啶-4-基）甲基]吡啶-2（1H） - 酮衍生物，其立体异构体，药学上可接受的盐或溶剂合物。上述化合物具有5-羟色胺1A受体配体和选择性5-羟色胺再摄取抑制剂的双重活性。还提供了上述化合物的制备方法，这些化合物用于预防或治疗与5-羟色胺系统功能障碍有关的神经系统疾病的用途和含有这些化合物的药物组合物。

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