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1. 发明授权

US07650185B2 System and method for walking an implantable medical device from a sleep state 有权
标题翻译：从植入式医疗装置从睡眠状态走路的系统和方法
公开(公告)号：US07650185B2
公开(公告)日：2010-01-19
申请号：US11380112
申请日：2006-04-25
申请人： Keith R. Maile , Abhijeet V. Chavan , Von Arx A. Jeffrey , Cheng Zhang
发明人： Keith R. Maile , Abhijeet V. Chavan , Von Arx A. Jeffrey , Cheng Zhang
IPC分类号： A61N1/362
CPC分类号： A61N1/37252 , A61B5/0031 , A61B2560/0209 , A61N1/3706 , A61N1/37217 , A61N1/37264 , A61N1/37288
摘要： A system and method for waking up an implantable medical device (“IMD”) from a sleep state in which power consumption by the IMD is essentially zero. The IMD may be adapted to perform one or more designated measurement and/or therapeutic functions. In one embodiment, the IMD includes a wake-up sensor that is adapted to sense the presence or absence of a wake-up field generated by another IMD or an external device. The wake-up field may, in some embodiments, be an electromagnetic field, a magnetic field, or a physiologically sub-threshold excitation current (i.e., E-field). Upon sensing by the wake-up sensor of the wake-up field, other components of the IMD, which may include a controller, a sensing and/or therapy module, and/or a communications module, are awakened to perform one or more designated functions.
摘要翻译：一种用于将可植入医疗装置（“IMD”）从睡眠状态唤醒的系统和方法，其中IMD的功率消耗基本为零。 IMD可以适于执行一个或多个指定的测量和/或治疗功能。在一个实施例中，IMD包括适于感测由另一IMD或外部设备产生的唤醒场的存在或不存在的唤醒传感器。在一些实施例中，唤醒场可以是电磁场，磁场或生理学亚阈值激励电流（即，电场）。唤醒传感器感应唤醒场后，可以包括控制器，感测和/或治疗模块和/或通信模块的IMD的其他部件被唤醒以执行一个或多个指定的功能。

2. 发明授权

US08777863B2 Implantable medical device with internal piezoelectric energy harvesting 有权
标题翻译：具有内部压电能量收集的植入式医疗器械
公开(公告)号：US08777863B2
公开(公告)日：2014-07-15
申请号：US12774976
申请日：2010-05-06
申请人： Thomas W. Piaget , Bin Mi , Lance E. Juffer , Keith R. Maile , Abhijeet V. Chavan , Cheng Zhang
发明人： Thomas W. Piaget , Bin Mi , Lance E. Juffer , Keith R. Maile , Abhijeet V. Chavan , Cheng Zhang
IPC分类号： A61B5/02
CPC分类号： H01L41/1138 , A61B5/0031 , A61B5/0215 , H02N2/18
摘要： Methods, systems, and apparatus for powering and/or recharging medical devices implanted within the body are described. An illustrative power generation module disposable within the interior space of an implantable medical device includes a module body that defines an interior cavity as well as a flexible diaphragm that spans the interior cavity. The flexible diaphragm includes a first electrical conductor, a piezoelectric layer disposed adjacent to the first electrical conductor, and a second electrical conductor disposed adjacent to the piezoelectric layer. The piezoelectric layer is configured to displace within the interior cavity and generate a voltage differential between the first electrical conductor and the second electrical conductor.
摘要翻译：描述了植入体内的医疗装置的供电和/或再充电的方法，系统和装置。在可植入医疗装置的内部空间内可放置的说明性发电模块包括限定内腔的模块主体以及跨越内腔的柔性隔膜。柔性隔膜包括第一电导体，邻近第一电导体设置的压电层和邻近压电层设置的第二电导体。压电层被配置为在内腔内移位，并在第一电导体和第二电导体之间产生电压差。

3. 发明授权

US07570998B2 Acoustic communication transducer in implantable medical device header 有权
标题翻译：可植入医疗器械头部的声学通讯传感器
公开(公告)号：US07570998B2
公开(公告)日：2009-08-04
申请号：US11780903
申请日：2007-07-20
申请人： Cheng Zhang , Thomas W. Piaget , Abhijeet V. Chavan , Keith R. Maile , Ron A. Balczewski
发明人： Cheng Zhang , Thomas W. Piaget , Abhijeet V. Chavan , Keith R. Maile , Ron A. Balczewski
IPC分类号： A61N1/00
CPC分类号： A61N1/37217 , A61B5/0028 , A61B5/0031 , A61B5/021 , A61B5/14532 , A61B8/4281
摘要： An implantable medical device is adapted for implantation into body tissue. The implantable medical device comprises a housing and a header coupled to the housing. A cavity is located in the header. An ultrasonic transducer adapted to transmit acoustic waves at a communication frequency is located in the cavity, and a coupling surface is interposed between the ultrasonic transducer and the body tissue and is acoustically coupled with the body tissue.
摘要翻译：可植入医疗装置适于植入人体组织。可植入医疗装置包括壳体和联接到壳体的头部。一个空腔位于头部。适于以通信频率传输声波的超声波换能器位于空腔中，并且耦合表面插入在超声换能器和身体组织之间并与身体组织进行声学耦合。

4. 发明申请

US20100317977A1 IMPLANTABLE MEDICAL DEVICE WITH INTERNAL PIEZOELECTRIC ENERGY HARVESTING 有权
标题翻译：具有内部压电能量收集的可植入医疗器械
公开(公告)号：US20100317977A1
公开(公告)日：2010-12-16
申请号：US12774976
申请日：2010-05-06
申请人： Thomas W. Piaget , Bin Mi , Lance E. Juffer , Keith R. Maile , Abhijeet V. Chavan , Cheng Zhang
发明人： Thomas W. Piaget , Bin Mi , Lance E. Juffer , Keith R. Maile , Abhijeet V. Chavan , Cheng Zhang
IPC分类号： A61B5/0215 , H02N2/18
CPC分类号： H01L41/1138 , A61B5/0031 , A61B5/0215 , H02N2/18
摘要： Methods, systems, and apparatus for powering and/or recharging medical devices implanted within the body are described. An illustrative power generation module disposable within the interior space of an implantable medical device includes a module body that defines an interior cavity as well as a flexible diaphragm that spans the interior cavity. The flexible diaphragm includes a first electrical conductor, a piezoelectric layer disposed adjacent to the first electrical conductor, and a second electrical conductor disposed adjacent to the piezoelectric layer. The piezoelectric layer is configured to displace within the interior cavity and generate a voltage differential between the first electrical conductor and the second electrical conductor.
摘要翻译：描述了植入体内的医疗装置的供电和/或再充电的方法，系统和装置。在可植入医疗装置的内部空间内可放置的说明性发电模块包括限定内腔的模块主体以及跨越内腔的柔性隔膜。柔性隔膜包括第一电导体，邻近第一电导体设置的压电层和邻近压电层设置的第二电导体。压电层被配置为在内腔内移位，并在第一电导体和第二电导体之间产生电压差。

5. 发明授权

US08506495B2 Implantable medical devices with piezoelectric anchoring member 有权
标题翻译：具有压电锚固构件的植入式医疗器械
公开(公告)号：US08506495B2
公开(公告)日：2013-08-13
申请号：US12774983
申请日：2010-05-06
申请人： Bin Mi , Lance E. Juffer , Keith R. Maile , Abhijeet V. Chavan , Thomas W. Piaget
发明人： Bin Mi , Lance E. Juffer , Keith R. Maile , Abhijeet V. Chavan , Thomas W. Piaget
IPC分类号： A61B5/02
CPC分类号： A61N1/36564 , A61B5/0031 , A61B5/0215 , A61N1/37205 , A61N1/37217 , A61N1/37288 , A61N1/375
摘要： Methods, systems, and apparatus for powering and/or recharging medical devices implanted within the body are described. An illustrative implantable medical device includes a housing having an internal cavity and a flexible anchor assembly that is coupled to the housing. The flexible anchor assembly includes a first electrical conductor, a second electrical conductor, and a piezoelectric layer that is disposed between the first and second electrical conductors and that is configured to displace in response to a physiologic force applied to the flexible anchor assembly and generate a voltage differential between the first and second electrical conductors. The implantable medical device includes power circuitry that converts the voltage differential between the first and second electrical conductors into an operating current for powering one or more components within the implantable medical device and/or for recharging a rechargeable power supply within the device.
摘要翻译：描述了植入体内的医疗装置的供电和/或再充电的方法，系统和装置。示例性可植入医疗装置包括具有内腔的壳体和联接到壳体的柔性锚固组件。柔性锚固组件包括第一电导体，第二电导体和压电层，其被设置在第一和第二电导体之间，并被配置为响应于施加到柔性锚固组件的生理力而移位并产生第一和第二电导体之间的电压差。可植入医疗装置包括电力电路，其将第一和第二电导体之间的电压差转换成用于为可植入医疗装置内的一个或多个部件供电的动作电流和/或用于为装置内的可再充电电源再充电。

6. 发明授权

US07949396B2 Ultrasonic transducer for a metallic cavity implated medical device 有权
标题翻译：用于金属腔的超声换能器涉及医疗装置
公开(公告)号：US07949396B2
公开(公告)日：2011-05-24
申请号：US11780992
申请日：2007-07-20
申请人： Bin Mi , Abhijeet V. Chavan , Keith R. Maile
发明人： Bin Mi , Abhijeet V. Chavan , Keith R. Maile
IPC分类号： A61N1/375
CPC分类号： A61N1/37288 , A61B5/0028 , A61N1/37217
摘要： An implantable medical device comprising a housing and an ultrasonic transducer having a communication frequency coupled to a portion of the housing. The housing resonates at the communication frequency, and a casing is coupled to the housing and disposed over the ultrasonic transducer. The casing is adapted to amplify the deformation of the ultrasonic transducer in a bending mode and transfer the bending moment to the housing. An implantable medical device comprising a housing having an upper portion and a lower portion. A first ultrasonic transducer is coupled to a first connection rod and is coaxial with the first connection rod. The first ultrasonic transducer and first connection rod are interposed between the upper and lower portions such that the first ultrasonic transducer is adapted to vibrate the upper and lower portions simultaneously. A method of optimizing an ultrasonic transducer and a housing of an implantable medical device.
摘要翻译：一种可植入医疗装置，包括壳体和具有耦合到壳体的一部分的通信频率的超声换能器。壳体以通信频率谐振，并且壳体耦合到壳体并且设置在超声换能器上。壳体适于在弯曲模式下放大超声波换能器的变形，并将弯矩转移到壳体。一种可植入医疗装置，包括具有上部和下部的壳体。第一超声换能器联接到第一连接杆并且与第一连接杆同轴。第一超声波换能器和第一连接杆插入在上部和下部之间，使得第一超声波换能器适于同时振动上部和下部。一种优化超声换能器和可植入医疗装置的壳体的方法。

7. 发明申请

US20100317929A1 IMPLANTABLE MEDICAL DEVICES WITH PIEZOELECTRIC ANCHORING MEMBER 有权
标题翻译：具有压电锚固构件的可植入医疗装置
公开(公告)号：US20100317929A1
公开(公告)日：2010-12-16
申请号：US12774983
申请日：2010-05-06
申请人： Bin Mi , Lance E. Juffer , Keith R. Maile , Abhijeet V. Chavan , Thomas W. Piaget
发明人： Bin Mi , Lance E. Juffer , Keith R. Maile , Abhijeet V. Chavan , Thomas W. Piaget
IPC分类号： A61B5/00 , A61N1/365
CPC分类号： A61N1/36564 , A61B5/0031 , A61B5/0215 , A61N1/37205 , A61N1/37217 , A61N1/37288 , A61N1/375
摘要： Methods, systems, and apparatus for powering and/or recharging medical devices implanted within the body are described. An illustrative implantable medical device includes a housing having an internal cavity and a flexible anchor assembly that is coupled to the housing. The flexible anchor assembly includes a first electrical conductor, a second electrical conductor, and a piezoelectric layer that is disposed between the first and second electrical conductors and that is configured to displace in response to a physiologic force applied to the flexible anchor assembly and generate a voltage differential between the first and second electrical conductors. The implantable medical device includes power circuitry that converts the voltage differential between the first and second electrical conductors into an operating current for powering one or more components within the implantable medical device and/or for recharging a rechargeable power supply within the device.
摘要翻译：描述了植入体内的医疗装置的供电和/或再充电的方法，系统和装置。示例性可植入医疗装置包括具有内腔的壳体和联接到壳体的柔性锚固组件。柔性锚固组件包括第一电导体，第二电导体和压电层，其被设置在第一和第二电导体之间，并被配置为响应于施加到柔性锚固组件的生理力而移位并产生第一和第二电导体之间的电压差。可植入医疗装置包括电力电路，其将第一和第二电导体之间的电压差转换成用于为可植入医疗装置内的一个或多个部件供电的动作电流和/或用于为装置内的可再充电电源再充电。

8. 发明授权

US08548592B2 Ultrasonic transducer for a metallic cavity implanted medical device 有权
标题翻译：用于金属腔植入医疗器械的超声换能器
公开(公告)号：US08548592B2
公开(公告)日：2013-10-01
申请号：US13082954
申请日：2011-04-08
申请人： Bin Mi , Abhijeet V. Chavan , Keith R. Maile
发明人： Bin Mi , Abhijeet V. Chavan , Keith R. Maile
IPC分类号： A61N1/375
CPC分类号： A61N1/37288 , A61B5/0028 , A61N1/37217
摘要： Implantable medical devices including an ultrasonic transducer and methods of optimizing an ultrasonic transducer of an implantable medical device are disclosed. The implantable medical device can include a housing, an ultrasonic transducer disposed within an interior of the housing, and a limiting structure configured to constrain deformation of the ultrasonic transducer. The limiting structure can include a separate structure coupled to the housing, or can comprise a resonant portion of the housing itself. During operation, the ultrasonic transducer is configured to communicate at a frequency at or near a resonant frequency of the housing.
摘要翻译：公开了包括超声换能器和优化可植入医疗装置的超声换能器的方法的可植入医疗装置。可植入医疗装置可以包括壳体，设置在壳体内部的超声波换能器以及限制超声换能器变形的限制结构。限制结构可以包括耦合到壳体的单独结构，或者可以包括壳体本身的谐振部分。在操作期间，超声波换能器被配置为在壳体的谐振频率处或接近谐振频率处的频率进行通信。

9. 发明申请

US20090312650A1 IMPLANTABLE PRESSURE SENSOR WITH AUTOMATIC MEASUREMENT AND STORAGE CAPABILITIES 审中-公开
标题翻译：具有自动测量和存储能力的可植入压力传感器
公开(公告)号：US20090312650A1
公开(公告)日：2009-12-17
申请号：US12464508
申请日：2009-05-12
申请人： Keith R. Maile , Abhijeet V. Chavan , Paul J. Huelskamp
发明人： Keith R. Maile , Abhijeet V. Chavan , Paul J. Huelskamp
IPC分类号： A61B5/02
CPC分类号： A61B5/0215 , A61B5/0002 , A61B5/02108 , A61B5/076 , A61B5/7285 , A61B2560/0209
摘要： Methods for activating implantable medical devices within a patient's body are disclosed. An illustrative method includes activating an implantable medical device from a low-power state to an awake state in response to a scheduled time event, sensing one or more pressure measurements within the body, computing an average pressure measurement based on the sensed pressure measurements, storing the average pressure measurement within a memory of the implantable medical device, and then returning the device to the low-power state. A triggering event such as the detection of patient activity or motion can also be used to activate the implantable medical device between the low-power state and an active state.
摘要翻译：公开了用于激活患者体内植入式医疗装置的方法。一种说明性方法包括响应于预定的时间事件将可植入医疗装置从低功率状态激活到唤醒状态，感测身体内的一个或多个压力测量值，基于感测到的压力测量计算平均压力测量值，存储在可植入医疗装置的存储器内的平均压力测量值，然后将装置返回到低功率状态。也可以使用诸如检测患者活动或运动的触发事件来在低功率状态和活动状态之间激活可植入医疗装置。

10. 发明申请

US20090198307A1 DIRECT INDUCTIVE/ACOUSTIC CONVERTER FOR IMPLANTABLE MEDICAL DEVICE 有权
标题翻译：用于可植入医疗器械的直接电感/呼吸转换器
公开(公告)号：US20090198307A1
公开(公告)日：2009-08-06
申请号：US12357460
申请日：2009-01-22
申请人： Bin Mi , Abhijeet V. Chavan , Keith R. Maile
发明人： Bin Mi , Abhijeet V. Chavan , Keith R. Maile
IPC分类号： A61N1/08 , A61B5/07
CPC分类号： A61N1/37211 , A61B5/0031 , A61B5/01 , A61B5/0215 , A61B5/026 , A61N1/08 , A61N1/37217
摘要： Systems and methods for communicating with or powering implantable medical devices using a direct inductive/acoustic telemetry link are disclosed. An illustrative system includes an interrogator device located outside of the patient's body, an implantable medical device including an energy translator circuit adapted to convert inductive or RF signals received from the interrogator device into an acoustic signal for driving an acoustic transducer, and a remote device adapted to sense one or more parameters within the body.
摘要翻译：公开了使用直接感应/声学遥测链路与可植入医疗装置通信或供电的系统和方法。说明性系统包括位于患者身体外部的询问器装置，可植入医疗装置，其包括能量转换器电路，其适于将从询问器装置接收的感应或RF信号转换成用于驱动声换能器的声信号，以及适配器感测身体内的一个或多个参数。

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